FYN (FYN proto-oncogene, Src family tyrosine kinase) - Rat Genome Database
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Gene: FYN (FYN proto-oncogene, Src family tyrosine kinase) Homo sapiens
Analyze
Symbol: FYN
Name: FYN proto-oncogene, Src family tyrosine kinase
RGD ID: 731929
HGNC Page HGNC
Description: Exhibits several functions, including disordered domain specific binding activity; identical protein binding activity; and signaling receptor binding activity. Involved in several processes, including T cell receptor signaling pathway; cellular response to amyloid-beta; and peptidyl-tyrosine phosphorylation. Localizes to cytosol; endosome; and plasma membrane. Colocalizes with membrane raft. Implicated in Alzheimer's disease and schizophrenia. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c-syn protooncogene; FYN oncogene related to SRC, FGR, YES; MGC45350; OKT3-induced calcium influx regulator; p59-FYN; protein-tyrosine kinase fyn; proto-oncogene c-Fyn; proto-oncogene Syn; proto-oncogene tyrosine-protein kinase fyn; SLK; src-like kinase; src/yes-related novel; SYN; tyrosine kinase p59fyn(T); tyrosine-protein kinase Fyn
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6111,660,332 - 111,873,452 (-)EnsemblGRCh38hg38GRCh38
GRCh386111,660,332 - 111,873,452 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376111,981,535 - 112,194,655 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366112,089,178 - 112,301,320 (-)NCBINCBI36hg18NCBI36
Build 346112,089,179 - 112,186,978NCBI
Celera6112,729,071 - 112,941,209 (-)NCBI
Cytogenetic Map6q21NCBI
HuRef6109,554,123 - 109,767,060 (-)NCBIHuRef
CHM1_16112,244,349 - 112,457,405 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (EXP)
(-)-epigallocatechin 3-gallate  (EXP)
(S)-nicotine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-arachidonoylglycerol  (ISO)
2-methylcholine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-azacytidine  (EXP)
5-fluorouracil  (EXP)
acetamide  (ISO)
aflatoxin B1  (EXP,ISO)
alachlor  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
antigen  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP,ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
butanal  (EXP)
Butylparaben  (ISO)
caffeine  (ISO)
calcium dichloride  (EXP)
captan  (ISO)
carmustine  (EXP)
chromium(6+)  (EXP)
cisplatin  (EXP)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (EXP)
cyclophosphamide  (EXP)
cyclosporin A  (EXP,ISO)
cytarabine  (EXP)
D-gluconic acid  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diazinon  (EXP,ISO)
dibutyl phthalate  (ISO)
dieldrin  (ISO)
diuron  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
enzacamene  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
etoposide  (EXP,ISO)
folpet  (ISO)
gentamycin  (ISO)
glutathione  (EXP)
haloperidol  (ISO)
L-ascorbic acid  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
linuron  (ISO)
lithium chloride  (ISO)
LY294002  (ISO)
methamphetamine  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
methylparaben  (EXP)
methylseleninic acid  (EXP)
mitomycin C  (EXP)
mitoxantrone  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (EXP)
nickel atom  (EXP)
nickel sulfate  (EXP)
nicotine  (EXP)
O-methyleugenol  (EXP)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentanal  (EXP)
phenobarbital  (ISO)
phenylarsine oxide  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
piroxicam  (EXP)
ponatinib  (EXP)
potassium chromate  (EXP)
potassium dichromate  (EXP)
prochloraz  (ISO)
procymidone  (ISO)
propanal  (EXP)
resveratrol  (EXP)
Salinomycin  (EXP)
SB 431542  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
succimer  (EXP)
sunitinib  (EXP)
tamibarotene  (EXP)
titanium dioxide  (ISO)
topotecan  (ISO)
tremolite asbestos  (ISO)
trichostatin A  (EXP)
Triptolide  (ISO)
urethane  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin E  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activated T cell proliferation  (IEA,ISO)
adaptive immune response  (IEA)
axon guidance  (TAS)
blood coagulation  (TAS)
calcium ion transport  (NAS)
cell differentiation  (IBA)
cell surface receptor signaling pathway  (ISO)
cellular response to amyloid-beta  (IMP)
cellular response to glycine  (ISO,ISS)
cellular response to growth factor stimulus  (ISO)
cellular response to L-glutamate  (ISO,ISS)
cellular response to peptide hormone stimulus  (IEA,ISO)
cellular response to platelet-derived growth factor stimulus  (IEA,ISO)
cellular response to transforming growth factor beta stimulus  (IEA,ISO)
cytokine-mediated signaling pathway  (TAS)
dendrite morphogenesis  (IEA,ISO)
dendritic spine maintenance  (TAS)
detection of mechanical stimulus involved in sensory perception of pain  (IEA,ISO)
ephrin receptor signaling pathway  (TAS)
Fc-gamma receptor signaling pathway involved in phagocytosis  (TAS)
feeding behavior  (TAS)
forebrain development  (IEA,ISO)
heart process  (IGI,ISO)
innate immune response  (IBA)
intracellular signal transduction  (TAS)
learning  (TAS)
leukocyte migration  (TAS)
MAPK cascade  (TAS)
modulation of chemical synaptic transmission  (IEA,ISO)
negative regulation of dendritic spine maintenance  (ISO,ISS)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IEA,ISO)
negative regulation of gene expression  (IEA,ISO)
negative regulation of hydrogen peroxide biosynthetic process  (ISO,ISS)
negative regulation of inflammatory response to antigenic stimulus  (TAS)
negative regulation of neuron apoptotic process  (IEA,ISO)
negative regulation of oxidative stress-induced cell death  (ISO,ISS)
negative regulation of protein catabolic process  (IEA,ISO)
negative regulation of protein ubiquitination  (IEA,ISO)
neuron migration  (IEA,ISO)
peptidyl-tyrosine phosphorylation  (IMP,ISO,ISS,TAS)
platelet activation  (TAS)
positive regulation of cysteine-type endopeptidase activity  (ISO,ISS)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (IEA,ISO)
positive regulation of neuron death  (ISO,ISS)
positive regulation of neuron projection development  (IEA,ISO)
positive regulation of non-membrane spanning protein tyrosine kinase activity  (TAS)
positive regulation of phosphatidylinositol 3-kinase signaling  (IEA,ISO)
positive regulation of protein kinase B signaling  (TAS)
positive regulation of protein localization to membrane  (TAS)
positive regulation of protein localization to nucleus  (IEA,ISO)
positive regulation of protein targeting to membrane  (ISO,ISS)
positive regulation of tyrosine phosphorylation of STAT protein  (IEA,ISO)
protein autophosphorylation  (IEA,ISO)
protein phosphorylation  (ISO,NAS,TAS)
regulation of calcium ion import across plasma membrane  (ISO,ISS)
regulation of cell shape  (ISO,ISS)
regulation of defense response to virus by virus  (TAS)
regulation of glutamate receptor signaling pathway  (ISO,ISS)
regulation of peptidyl-tyrosine phosphorylation  (ISO,ISS)
response to amyloid-beta  (ISO,ISS)
response to drug  (IEA,ISO)
response to ethanol  (IEA,ISO)
response to hydrogen peroxide  (ISO,ISS)
response to singlet oxygen  (ISO,ISS)
stimulatory C-type lectin receptor signaling pathway  (TAS)
T cell costimulation  (TAS)
T cell receptor signaling pathway  (IBA,IDA)
transmembrane receptor protein tyrosine kinase signaling pathway  (IBA)
vascular endothelial growth factor receptor signaling pathway  (TAS)

References

Additional References at PubMed
PMID:82   PMID:119942   PMID:1334406   PMID:1351058   PMID:1361685   PMID:1381360   PMID:1384720   PMID:1385527   PMID:1387715   PMID:1446976   PMID:1454062   PMID:1530920  
PMID:1544885   PMID:1661130   PMID:1696179   PMID:1699196   PMID:1715582   PMID:1717997   PMID:1985196   PMID:3099169   PMID:3330788   PMID:3526330   PMID:7504057   PMID:7515933  
PMID:7516469   PMID:7517401   PMID:7520528   PMID:7521304   PMID:7525550   PMID:7537495   PMID:7545683   PMID:7565724   PMID:7588629   PMID:7589084   PMID:7589101   PMID:7589480  
PMID:7595520   PMID:7642581   PMID:7664083   PMID:7681396   PMID:7682059   PMID:7685273   PMID:7687536   PMID:7687537   PMID:7722293   PMID:7760813   PMID:7782294   PMID:7822789  
PMID:7859737   PMID:7929439   PMID:8058772   PMID:8104794   PMID:8183901   PMID:8262983   PMID:8264796   PMID:8294442   PMID:8394019   PMID:8395016   PMID:8483935   PMID:8493579  
PMID:8566014   PMID:8621384   PMID:8621719   PMID:8626376   PMID:8626543   PMID:8631859   PMID:8647168   PMID:8655574   PMID:8662998   PMID:8671590   PMID:8681387   PMID:8756631  
PMID:8760790   PMID:8798684   PMID:8805332   PMID:8805554   PMID:8810341   PMID:8883579   PMID:8900205   PMID:8910336   PMID:8961927   PMID:8980254   PMID:8995358   PMID:8995379  
PMID:9028946   PMID:9032261   PMID:9038134   PMID:9043947   PMID:9045636   PMID:9047237   PMID:9060467   PMID:9079653   PMID:9091579   PMID:9104812   PMID:9118959   PMID:9121430  
PMID:9169421   PMID:9185665   PMID:9188452   PMID:9195899   PMID:9195918   PMID:9196040   PMID:9207119   PMID:9230816   PMID:9252391   PMID:9269777   PMID:9295288   PMID:9311917  
PMID:9344703   PMID:9344857   PMID:9351806   PMID:9351809   PMID:9360983   PMID:9366405   PMID:9368621   PMID:9417082   PMID:9425276   PMID:9446569   PMID:9507006   PMID:9531288  
PMID:9535845   PMID:9535867   PMID:9553134   PMID:9573028   PMID:9576921   PMID:9603925   PMID:9632142   PMID:9648856   PMID:9670010   PMID:9674711   PMID:9677430   PMID:9687533  
PMID:9710204   PMID:9712716   PMID:9741627   PMID:9748251   PMID:9750131   PMID:9756930   PMID:9763511   PMID:9778343   PMID:9799234   PMID:9804857   PMID:9819391   PMID:9822663  
PMID:9837776   PMID:9837978   PMID:9846481   PMID:9856337   PMID:9890970   PMID:9892651   PMID:9973379   PMID:10022833   PMID:10089404   PMID:10092522   PMID:10196263   PMID:10209036  
PMID:10212213   PMID:10224664   PMID:10229084   PMID:10339567   PMID:10383400   PMID:10409671   PMID:10435619   PMID:10447714   PMID:10458595   PMID:10482988   PMID:10498895   PMID:10532312  
PMID:10544125   PMID:10551884   PMID:10564280   PMID:10570256   PMID:10571044   PMID:10571082   PMID:10586033   PMID:10591186   PMID:10629042   PMID:10636929   PMID:10642173   PMID:10708762  
PMID:10733577   PMID:10739664   PMID:10744724   PMID:10764799   PMID:10790433   PMID:10799548   PMID:10804218   PMID:10816433   PMID:10829062   PMID:10858437   PMID:10861086   PMID:10867021  
PMID:10871840   PMID:10872802   PMID:10896916   PMID:10921922   PMID:10945997   PMID:11005864   PMID:11024032   PMID:11075717   PMID:11078745   PMID:11087735   PMID:11110698   PMID:11121167  
PMID:11149959   PMID:11157475   PMID:11158295   PMID:11162638   PMID:11204284   PMID:11239464   PMID:11262396   PMID:11278378   PMID:11278857   PMID:11298344   PMID:11353545   PMID:11356869  
PMID:11423543   PMID:11448999   PMID:11466305   PMID:11483358   PMID:11483655   PMID:11526103   PMID:11536198   PMID:11546790   PMID:11594778   PMID:11598189   PMID:11604131   PMID:11677266  
PMID:11684709   PMID:11711534   PMID:11724572   PMID:11739737   PMID:11741599   PMID:11741929   PMID:11744621   PMID:11777936   PMID:11806999   PMID:11820784   PMID:11826099   PMID:11839780  
PMID:11943772   PMID:11943848   PMID:11960376   PMID:11983687   PMID:11994282   PMID:12084815   PMID:12089510   PMID:12096713   PMID:12138090   PMID:12150984   PMID:12171928   PMID:12181444  
PMID:12218089   PMID:12231245   PMID:12237775   PMID:12244095   PMID:12244174   PMID:12368035   PMID:12370810   PMID:12372285   PMID:12374739   PMID:12408980   PMID:12419528   PMID:12426371  
PMID:12431372   PMID:12450793   PMID:12458214   PMID:12471123   PMID:12477932   PMID:12496362   PMID:12509223   PMID:12524444   PMID:12526739   PMID:12529448   PMID:12538589   PMID:12545174  
PMID:12558988   PMID:12589038   PMID:12640114   PMID:12660731   PMID:12668668   PMID:12695509   PMID:12697812   PMID:12721299   PMID:12730241   PMID:12753742   PMID:12788081   PMID:12835311  
PMID:12846735   PMID:12857875   PMID:12893833   PMID:12917446   PMID:12923167   PMID:12932824   PMID:12941616   PMID:14506255   PMID:14517306   PMID:14530346   PMID:14574404   PMID:14625311  
PMID:14647465   PMID:14662334   PMID:14675807   PMID:14684825   PMID:14702039   PMID:14707117   PMID:14757743   PMID:14761954   PMID:14761972   PMID:14965316   PMID:14980517   PMID:14993658  
PMID:15033366   PMID:15078178   PMID:15082191   PMID:15098360   PMID:15144186   PMID:15169881   PMID:15173175   PMID:15175272   PMID:15190072   PMID:15206927   PMID:15208330   PMID:15345594  
PMID:15345598   PMID:15356202   PMID:15489334   PMID:15491611   PMID:15494732   PMID:15514010   PMID:15536091   PMID:15537652   PMID:15556646   PMID:15557120   PMID:15588985   PMID:15611048  
PMID:15638726   PMID:15707590   PMID:15713745   PMID:15784897   PMID:15831486   PMID:15872086   PMID:15925565   PMID:16014719   PMID:16115884   PMID:16145685   PMID:16237174   PMID:16316995  
PMID:16344560   PMID:16374509   PMID:16387660   PMID:16400523   PMID:16454711   PMID:16479011   PMID:16503409   PMID:16537602   PMID:16597701   PMID:16636290   PMID:16640565   PMID:16713569  
PMID:16777849   PMID:16782058   PMID:16818765   PMID:16831868   PMID:16860569   PMID:16882656   PMID:16888650   PMID:16891393   PMID:16899217   PMID:16921024   PMID:16938345   PMID:16964398  
PMID:16966330   PMID:16979591   PMID:16983070   PMID:17094785   PMID:17129785   PMID:17130124   PMID:17164290   PMID:17189269   PMID:17192257   PMID:17334644   PMID:17417065   PMID:17460065  
PMID:17462920   PMID:17474147   PMID:17526495   PMID:17599905   PMID:17701175   PMID:17703099   PMID:17785434   PMID:17925405   PMID:17943724   PMID:18056706   PMID:18067320   PMID:18089558  
PMID:18156174   PMID:18174230   PMID:18180382   PMID:18267011   PMID:18337055   PMID:18467332   PMID:18564062   PMID:18628988   PMID:18697750   PMID:18710921   PMID:18714047   PMID:18842137  
PMID:18849153   PMID:18922801   PMID:18978678   PMID:18991950   PMID:19131339   PMID:19151721   PMID:19258392   PMID:19258394   PMID:19290918   PMID:19330793   PMID:19432816   PMID:19468241  
PMID:19501919   PMID:19542604   PMID:19567819   PMID:19690143   PMID:19711372   PMID:19728795   PMID:19733625   PMID:19805512   PMID:19807924   PMID:19816407   PMID:19913121   PMID:19917775  
PMID:19940238   PMID:19953087   PMID:19955046   PMID:19958149   PMID:19968749   PMID:20012528   PMID:20056178   PMID:20056645   PMID:20100835   PMID:20151426   PMID:20181947   PMID:20182632  
PMID:20360068   PMID:20506281   PMID:20534535   PMID:20628086   PMID:20658524   PMID:20682987   PMID:20855525   PMID:21098700   PMID:21269457   PMID:21298565   PMID:21364031   PMID:21371426  
PMID:21480388   PMID:21483438   PMID:21513984   PMID:21592972   PMID:21642356   PMID:21692989   PMID:21738584   PMID:21749309   PMID:21757751   PMID:21799250   PMID:21873635   PMID:21881001  
PMID:21900206   PMID:21952639   PMID:21988832   PMID:22161863   PMID:22189847   PMID:22354875   PMID:22403409   PMID:22422068   PMID:22442244   PMID:22447928   PMID:22474169   PMID:22641034  
PMID:22653218   PMID:22689581   PMID:22709448   PMID:22715382   PMID:22745667   PMID:22833681   PMID:22843238   PMID:22868769   PMID:22939624   PMID:22987042   PMID:23055554   PMID:23077515  
PMID:23128233   PMID:23131831   PMID:23175838   PMID:23188823   PMID:23250004   PMID:23300847   PMID:23386614   PMID:23405030   PMID:23438599   PMID:23455924   PMID:23497302   PMID:23535298  
PMID:23559827   PMID:23606749   PMID:23805846   PMID:23836527   PMID:23851594   PMID:23866081   PMID:23915951   PMID:23918783   PMID:24012003   PMID:24413734   PMID:24489884   PMID:24711643  
PMID:24815698   PMID:24852829   PMID:24882577   PMID:24886930   PMID:24976598   PMID:25036101   PMID:25036637   PMID:25130779   PMID:25156556   PMID:25241761   PMID:25416956   PMID:25503120  
PMID:25659154   PMID:25707991   PMID:25814554   PMID:25967238   PMID:26001218   PMID:26125726   PMID:26186194   PMID:26365631   PMID:26382759   PMID:26384592   PMID:26407913   PMID:26496610  
PMID:26561212   PMID:26624980   PMID:26646899   PMID:26786295   PMID:26848862   PMID:26888964   PMID:26892111   PMID:27001024   PMID:27040756   PMID:27193083   PMID:27335501   PMID:27342126  
PMID:27349276   PMID:27466485   PMID:27520374   PMID:27525436   PMID:27616741   PMID:27684187   PMID:27692963   PMID:27694211   PMID:28033507   PMID:28086240   PMID:28368000   PMID:28386764  
PMID:28393199   PMID:28514442   PMID:28560430   PMID:28811476   PMID:28923922   PMID:28948209   PMID:29091353   PMID:29140740   PMID:29269414   PMID:29348460   PMID:29486132   PMID:29555370  
PMID:29568061   PMID:29568343   PMID:29734505   PMID:29742433   PMID:29790812   PMID:29845934   PMID:29991678   PMID:30251698   PMID:30266665   PMID:30341149   PMID:30482845   PMID:30655611  
PMID:30978441   PMID:31036561   PMID:31091453   PMID:31189776   PMID:31201283   PMID:31391242   PMID:31413325   PMID:31515488   PMID:31586073   PMID:31957823   PMID:31980649   PMID:32291412  
PMID:32296183   PMID:32814053   PMID:32929078   PMID:33144569  


Genomics

Comparative Map Data
FYN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6111,660,332 - 111,873,452 (-)EnsemblGRCh38hg38GRCh38
GRCh386111,660,332 - 111,873,452 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376111,981,535 - 112,194,655 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366112,089,178 - 112,301,320 (-)NCBINCBI36hg18NCBI36
Build 346112,089,179 - 112,186,978NCBI
Celera6112,729,071 - 112,941,209 (-)NCBI
Cytogenetic Map6q21NCBI
HuRef6109,554,123 - 109,767,060 (-)NCBIHuRef
CHM1_16112,244,349 - 112,457,405 (-)NCBICHM1_1
Fyn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391039,245,735 - 39,441,377 (+)NCBIGRCm39mm39
GRCm381039,369,743 - 39,565,381 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1039,368,855 - 39,565,381 (+)EnsemblGRCm38mm10GRCm38
MGSCv371039,089,605 - 39,285,187 (+)NCBIGRCm37mm9NCBIm37
MGSCv361039,059,502 - 39,254,797 (+)NCBImm8
Celera1040,254,667 - 40,450,960 (+)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1020.51NCBI
Fyn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22042,767,733 - 42,960,903 (+)NCBI
Rnor_6.0 Ensembl2044,436,403 - 44,630,317 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02044,436,354 - 44,630,316 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02046,160,734 - 46,353,456 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42043,501,853 - 43,695,567 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12043,524,863 - 43,718,578 (+)NCBI
Celera2043,482,980 - 43,675,123 (+)NCBICelera
Cytogenetic Map20q12NCBI
Fyn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541136,401,842 - 36,512,054 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541136,403,156 - 36,597,660 (-)NCBIChiLan1.0ChiLan1.0
FYN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16113,545,944 - 113,732,893 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6113,545,944 - 113,604,451 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06109,469,750 - 109,684,086 (-)NCBIMhudiblu_PPA_v0panPan3
FYN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1268,075,184 - 68,316,541 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11268,105,060 - 68,316,630 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Fyn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936679388,500 - 588,518 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FYN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl177,585,439 - 77,810,581 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1177,584,675 - 77,810,605 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,249,062 - 87,253,260 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2187,146,809 - 87,191,215 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1p13NCBI
FYN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11361,988,265 - 62,218,756 (+)NCBI
ChlSab1.1 Ensembl1362,159,874 - 62,219,672 (+)Ensembl
Fyn
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624933248,298 - 456,933 (+)NCBI

Position Markers
D6S302  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376111,999,276 - 111,999,466UniSTSGRCh37
Build 366112,105,969 - 112,106,159RGDNCBI36
Celera6112,745,867 - 112,746,053RGD
Cytogenetic Map6q21UniSTS
Cytogenetic Map6q21-q22UniSTS
HuRef6109,571,879 - 109,572,063UniSTS
Marshfield Genetic Map6118.64UniSTS
Marshfield Genetic Map6118.64RGD
Genethon Genetic Map6118.7UniSTS
GeneMap99-GB4 RH Map6469.86UniSTS
Whitehead-YAC Contig Map6 UniSTS
NCBI RH Map61426.3UniSTS
RH48180  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,021,202 - 112,021,323UniSTSGRCh37
Build 366112,127,895 - 112,128,016RGDNCBI36
Celera6112,767,790 - 112,767,911RGD
Cytogenetic Map6q21UniSTS
HuRef6109,593,798 - 109,593,919UniSTS
GeneMap99-GB4 RH Map6478.13UniSTS
STS-N35086  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376111,982,045 - 111,982,177UniSTSGRCh37
Build 366112,088,738 - 112,088,870RGDNCBI36
Celera6112,728,631 - 112,728,763RGD
Cytogenetic Map6q21UniSTS
HuRef6109,554,633 - 109,554,765UniSTS
GeneMap99-GB4 RH Map6469.86UniSTS
NCBI RH Map61427.3UniSTS
AL023485  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,097,229 - 112,097,369UniSTSGRCh37
Build 366112,203,922 - 112,204,062RGDNCBI36
Celera6112,843,822 - 112,843,962RGD
Cytogenetic Map6q21UniSTS
HuRef6109,669,561 - 109,669,701UniSTS
RH46682  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,074,624 - 112,074,794UniSTSGRCh37
Build 366112,181,317 - 112,181,487RGDNCBI36
Celera6112,821,216 - 112,821,386RGD
Cytogenetic Map6q21UniSTS
HuRef6109,647,224 - 109,647,394UniSTS
GeneMap99-GB4 RH Map6478.13UniSTS
SHGC-31232  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,074,654 - 112,074,794UniSTSGRCh37
Build 366112,181,347 - 112,181,487RGDNCBI36
Celera6112,821,246 - 112,821,386RGD
Cytogenetic Map6q21UniSTS
HuRef6109,647,254 - 109,647,394UniSTS
Stanford-G3 RH Map64663.0UniSTS
GeneMap99-GB4 RH Map6473.11UniSTS
Whitehead-RH Map6690.0UniSTS
GeneMap99-G3 RH Map64966.0UniSTS
D6S2035  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,038,315 - 112,038,404UniSTSGRCh37
GRCh372161,128,755 - 161,128,844UniSTSGRCh37
Build 362160,837,001 - 160,837,090RGDNCBI36
Celera6112,784,903 - 112,784,992UniSTS
Celera2154,740,241 - 154,740,330RGD
Cytogenetic Map6q21UniSTS
Cytogenetic Map2q24.2UniSTS
HuRef6109,610,911 - 109,611,000UniSTS
HuRef2153,011,971 - 153,012,060UniSTS
RH76192  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376111,982,728 - 111,982,954UniSTSGRCh37
Build 366112,089,421 - 112,089,647RGDNCBI36
Celera6112,729,314 - 112,729,540RGD
Cytogenetic Map6q21UniSTS
HuRef6109,555,316 - 109,555,542UniSTS
SHGC-78694  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,031,888 - 112,032,189UniSTSGRCh37
Build 366112,138,581 - 112,138,882RGDNCBI36
Celera6112,778,476 - 112,778,777RGD
Cytogenetic Map6q21UniSTS
HuRef6109,604,484 - 109,604,785UniSTS
TNG Radiation Hybrid Map653525.0UniSTS
GDB:187104  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376111,982,730 - 111,982,881UniSTSGRCh37
Build 366112,089,423 - 112,089,574RGDNCBI36
Celera6112,729,316 - 112,729,467RGD
Cytogenetic Map6q21UniSTS
HuRef6109,555,318 - 109,555,469UniSTS
G20422  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,027,558 - 112,027,698UniSTSGRCh37
Build 366112,134,251 - 112,134,391RGDNCBI36
Celera6112,774,146 - 112,774,286RGD
Cytogenetic Map6q21UniSTS
HuRef6109,600,154 - 109,600,294UniSTS
A005Q39  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,027,558 - 112,027,698UniSTSGRCh37
Build 366112,134,251 - 112,134,391RGDNCBI36
Celera6112,774,146 - 112,774,286RGD
Cytogenetic Map6q21UniSTS
HuRef6109,600,154 - 109,600,294UniSTS
GeneMap99-GB4 RH Map6469.96UniSTS
NCBI RH Map61428.3UniSTS
RH46768  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,179,766 - 112,179,953UniSTSGRCh37
Build 366112,286,459 - 112,286,646RGDNCBI36
Celera6112,926,348 - 112,926,535RGD
Cytogenetic Map6q21UniSTS
HuRef6109,752,099 - 109,752,286UniSTS
GeneMap99-GB4 RH Map6486.58UniSTS
FYN_1578  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376111,982,462 - 111,983,118UniSTSGRCh37
Build 366112,089,155 - 112,089,811RGDNCBI36
Celera6112,729,048 - 112,729,704RGD
HuRef6109,555,050 - 109,555,706UniSTS
SHGC-960  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376111,999,278 - 111,999,486UniSTSGRCh37
Build 366112,105,971 - 112,106,179RGDNCBI36
Celera6112,745,869 - 112,746,073RGD
Cytogenetic Map6q21UniSTS
HuRef6109,571,881 - 109,572,083UniSTS
TNG Radiation Hybrid Map653545.0UniSTS
GeneMap99-G3 RH Map64975.0UniSTS
AL022469  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,057,986 - 112,058,173UniSTSGRCh37
Build 366112,164,679 - 112,164,866RGDNCBI36
Celera6112,804,574 - 112,804,761RGD
Cytogenetic Map6q21UniSTS
HuRef6109,630,583 - 109,630,770UniSTS
SHGC-30883  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376112,179,878 - 112,180,027UniSTSGRCh37
Build 366112,286,571 - 112,286,720RGDNCBI36
Celera6112,926,460 - 112,926,609RGD
Cytogenetic Map6q21UniSTS
HuRef6109,752,211 - 109,752,360UniSTS
Stanford-G3 RH Map64686.0UniSTS
GeneMap99-GB4 RH Map6473.22UniSTS
Whitehead-RH Map6690.0UniSTS
NCBI RH Map61429.4UniSTS
GeneMap99-G3 RH Map64989.0UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:6575
Count of miRNA genes:1224
Interacting mature miRNAs:1576
Transcripts:ENST00000229470, ENST00000229471, ENST00000354650, ENST00000356013, ENST00000368667, ENST00000368678, ENST00000368682, ENST00000462598, ENST00000462856, ENST00000467899, ENST00000467921, ENST00000471959, ENST00000476769, ENST00000484067, ENST00000487824, ENST00000491885, ENST00000495927, ENST00000495935, ENST00000496864, ENST00000517419, ENST00000518295, ENST00000518630, ENST00000520518, ENST00000521062, ENST00000521361, ENST00000523238, ENST00000523322, ENST00000523570, ENST00000523574, ENST00000524310, ENST00000538466
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2076 2404 1067 111 1517 62 3512 1045 3693 229 1226 1483 54 1204 1971 1
Low 348 581 652 508 421 399 842 1150 16 181 218 108 115 817 3 1
Below cutoff 10 4 4 10 4 1 4 9 9 16 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001370529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_153047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_153048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005266892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB451293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB451426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI187118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK056699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL109916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL158035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI552534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP391373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX781584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX872011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA570412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA815564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA922886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA931034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT584337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M20284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M20285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S74774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z97989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000229471   ⟹   ENSP00000229471
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,661,282 - 111,759,131 (-)Ensembl
RefSeq Acc Id: ENST00000354650   ⟹   ENSP00000346671
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,660,332 - 111,873,452 (-)Ensembl
RefSeq Acc Id: ENST00000368667   ⟹   ENSP00000357656
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,661,282 - 111,793,886 (-)Ensembl
RefSeq Acc Id: ENST00000368678   ⟹   ENSP00000357667
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,661,286 - 111,873,430 (-)Ensembl
RefSeq Acc Id: ENST00000368682   ⟹   ENSP00000357671
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,660,332 - 111,873,067 (-)Ensembl
RefSeq Acc Id: ENST00000462598   ⟹   ENSP00000429590
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,714,430 - 111,793,912 (-)Ensembl
RefSeq Acc Id: ENST00000462856   ⟹   ENSP00000427993
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,702,885 - 111,759,114 (-)Ensembl
RefSeq Acc Id: ENST00000467899
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,700,187 - 111,708,227 (-)Ensembl
RefSeq Acc Id: ENST00000467921
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,661,760 - 111,696,524 (-)Ensembl
RefSeq Acc Id: ENST00000471959
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,674,465 - 111,696,815 (-)Ensembl
RefSeq Acc Id: ENST00000476769
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,696,300 - 111,709,064 (-)Ensembl
RefSeq Acc Id: ENST00000484067   ⟹   ENSP00000428983
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,714,371 - 111,873,301 (-)Ensembl
RefSeq Acc Id: ENST00000487824   ⟹   ENSP00000430455
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,719,858 - 111,846,615 (-)Ensembl
RefSeq Acc Id: ENST00000491885
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,661,557 - 111,676,544 (-)Ensembl
RefSeq Acc Id: ENST00000495927
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,702,416 - 111,707,953 (-)Ensembl
RefSeq Acc Id: ENST00000495935
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,699,935 - 111,702,986 (-)Ensembl
RefSeq Acc Id: ENST00000496864
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,696,282 - 111,714,492 (-)Ensembl
RefSeq Acc Id: ENST00000517419   ⟹   ENSP00000429866
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,704,020 - 111,759,917 (-)Ensembl
RefSeq Acc Id: ENST00000518295   ⟹   ENSP00000428695
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,704,087 - 111,873,281 (-)Ensembl
RefSeq Acc Id: ENST00000518630   ⟹   ENSP00000429813
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,708,011 - 111,858,383 (-)Ensembl
RefSeq Acc Id: ENST00000520518   ⟹   ENSP00000429294
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,703,023 - 111,873,037 (-)Ensembl
RefSeq Acc Id: ENST00000521062   ⟹   ENSP00000428042
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,714,382 - 111,820,078 (-)Ensembl
RefSeq Acc Id: ENST00000521361
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,719,657 - 111,819,980 (-)Ensembl
RefSeq Acc Id: ENST00000523238   ⟹   ENSP00000430364
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,704,088 - 111,873,440 (-)Ensembl
RefSeq Acc Id: ENST00000523322
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,702,878 - 111,759,925 (-)Ensembl
RefSeq Acc Id: ENST00000523570   ⟹   ENSP00000428045
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,708,017 - 111,844,944 (-)Ensembl
RefSeq Acc Id: ENST00000523574   ⟹   ENSP00000429992
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,707,946 - 111,798,423 (-)Ensembl
RefSeq Acc Id: ENST00000524310   ⟹   ENSP00000428493
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,707,930 - 111,781,080 (-)Ensembl
RefSeq Acc Id: ENST00000538466   ⟹   ENSP00000440646
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,660,332 - 111,720,062 (-)Ensembl
RefSeq Acc Id: NM_001370529   ⟹   NP_001357458
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,660,332 - 111,759,917 (-)NCBI
RefSeq Acc Id: NM_002037   ⟹   NP_002028
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,660,332 - 111,873,452 (-)NCBI
GRCh376111,981,535 - 112,194,655 (-)NCBI
Build 366112,089,178 - 112,301,320 (-)NCBI Archive
HuRef6109,554,123 - 109,767,060 (-)NCBI
CHM1_16112,244,349 - 112,457,405 (-)NCBI
Sequence:
RefSeq Acc Id: NM_153047   ⟹   NP_694592
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,660,332 - 111,873,071 (-)NCBI
Build 366112,089,178 - 112,147,958 (-)NCBI Archive
HuRef6109,554,123 - 109,767,060 (-)NCBI
CHM1_16112,244,349 - 112,304,097 (-)NCBI
Sequence:
RefSeq Acc Id: NM_153048   ⟹   NP_694593
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,660,332 - 111,759,081 (-)NCBI
GRCh376111,981,535 - 112,194,655 (-)NCBI
Build 366112,089,178 - 112,186,978 (-)NCBI Archive
HuRef6109,554,123 - 109,767,060 (-)NCBI
CHM1_16112,244,349 - 112,343,163 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005266892   ⟹   XP_005266949
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,660,761 - 111,873,071 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010650   ⟹   XP_016866139
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,660,761 - 111,793,886 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010651   ⟹   XP_016866140
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,660,761 - 111,844,944 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010652   ⟹   XP_016866141
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,660,761 - 111,759,081 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010653   ⟹   XP_016866142
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,660,761 - 111,759,131 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010655   ⟹   XP_016866144
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,699,914 - 111,873,071 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001357458 (Get FASTA)   NCBI Sequence Viewer  
  NP_002028 (Get FASTA)   NCBI Sequence Viewer  
  NP_694592 (Get FASTA)   NCBI Sequence Viewer  
  NP_694593 (Get FASTA)   NCBI Sequence Viewer  
  XP_005266949 (Get FASTA)   NCBI Sequence Viewer  
  XP_016866139 (Get FASTA)   NCBI Sequence Viewer  
  XP_016866140 (Get FASTA)   NCBI Sequence Viewer  
  XP_016866141 (Get FASTA)   NCBI Sequence Viewer  
  XP_016866142 (Get FASTA)   NCBI Sequence Viewer  
  XP_016866144 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA36615 (Get FASTA)   NCBI Sequence Viewer  
  AAA52491 (Get FASTA)   NCBI Sequence Viewer  
  AAA52492 (Get FASTA)   NCBI Sequence Viewer  
  AAB33113 (Get FASTA)   NCBI Sequence Viewer  
  AAC08285 (Get FASTA)   NCBI Sequence Viewer  
  AAH32496 (Get FASTA)   NCBI Sequence Viewer  
  BAG51788 (Get FASTA)   NCBI Sequence Viewer  
  BAG70107 (Get FASTA)   NCBI Sequence Viewer  
  BAG70240 (Get FASTA)   NCBI Sequence Viewer  
  EAW48278 (Get FASTA)   NCBI Sequence Viewer  
  EAW48279 (Get FASTA)   NCBI Sequence Viewer  
  EAW48280 (Get FASTA)   NCBI Sequence Viewer  
  EAW48281 (Get FASTA)   NCBI Sequence Viewer  
  EAW48282 (Get FASTA)   NCBI Sequence Viewer  
  EAW48283 (Get FASTA)   NCBI Sequence Viewer  
  EAW48284 (Get FASTA)   NCBI Sequence Viewer  
  P06241 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_002028   ⟸   NM_002037
- Peptide Label: isoform a
- UniProtKB: P06241 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_694593   ⟸   NM_153048
- Peptide Label: isoform c
- UniProtKB: P06241 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_694592   ⟸   NM_153047
- Peptide Label: isoform b
- UniProtKB: P06241 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005266949   ⟸   XM_005266892
- Peptide Label: isoform X3
- UniProtKB: P06241 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016866140   ⟸   XM_017010651
- Peptide Label: isoform X1
- UniProtKB: P06241 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016866139   ⟸   XM_017010650
- Peptide Label: isoform X1
- UniProtKB: P06241 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016866142   ⟸   XM_017010653
- Peptide Label: isoform X1
- UniProtKB: P06241 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016866141   ⟸   XM_017010652
- Peptide Label: isoform X1
- UniProtKB: P06241 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016866144   ⟸   XM_017010655
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001357458   ⟸   NM_001370529
- Peptide Label: isoform a
RefSeq Acc Id: ENSP00000427993   ⟸   ENST00000462856
RefSeq Acc Id: ENSP00000429866   ⟸   ENST00000517419
RefSeq Acc Id: ENSP00000429813   ⟸   ENST00000518630
RefSeq Acc Id: ENSP00000229471   ⟸   ENST00000229471
RefSeq Acc Id: ENSP00000428695   ⟸   ENST00000518295
RefSeq Acc Id: ENSP00000429294   ⟸   ENST00000520518
RefSeq Acc Id: ENSP00000428042   ⟸   ENST00000521062
RefSeq Acc Id: ENSP00000428045   ⟸   ENST00000523570
RefSeq Acc Id: ENSP00000429992   ⟸   ENST00000523574
RefSeq Acc Id: ENSP00000430364   ⟸   ENST00000523238
RefSeq Acc Id: ENSP00000428983   ⟸   ENST00000484067
RefSeq Acc Id: ENSP00000440646   ⟸   ENST00000538466
RefSeq Acc Id: ENSP00000428493   ⟸   ENST00000524310
RefSeq Acc Id: ENSP00000357667   ⟸   ENST00000368678
RefSeq Acc Id: ENSP00000357656   ⟸   ENST00000368667
RefSeq Acc Id: ENSP00000357671   ⟸   ENST00000368682
RefSeq Acc Id: ENSP00000346671   ⟸   ENST00000354650
RefSeq Acc Id: ENSP00000430455   ⟸   ENST00000487824
RefSeq Acc Id: ENSP00000429590   ⟸   ENST00000462598
Protein Domains
Protein kinase   SH2   SH3

Promoters
RGD ID:7208917
Promoter ID:EPDNEW_H10203
Type:initiation region
Name:FYN_1
Description:FYN proto-oncogene, Src family tyrosine kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,873,452 - 111,873,512EPDNEW
RGD ID:6804255
Promoter ID:HG_KWN:54683
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:OTTHUMT00000043661,   UC010KDY.1
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,130,721 - 112,131,272 (-)MPROMDB
RGD ID:6804254
Promoter ID:HG_KWN:54684
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Lymphoblastoid
Transcripts:OTTHUMT00000043659,   OTTHUMT00000043660
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,136,221 - 112,136,772 (-)MPROMDB
RGD ID:6804257
Promoter ID:HG_KWN:54685
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:OTTHUMT00000043670
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,137,071 - 112,137,571 (-)MPROMDB
RGD ID:6804253
Promoter ID:HG_KWN:54686
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:OTTHUMT00000043658
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,142,371 - 112,142,871 (-)MPROMDB
RGD ID:6804252
Promoter ID:HG_KWN:54687
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:NM_153047
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,147,671 - 112,148,171 (-)MPROMDB
RGD ID:6804256
Promoter ID:HG_KWN:54688
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_2Hour
Transcripts:NM_153048,   OTTHUMT00000043665
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,186,621 - 112,187,522 (-)MPROMDB
RGD ID:6803978
Promoter ID:HG_KWN:54689
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000354650,   OTTHUMT00000043664,   OTTHUMT00000043667,   UC003PVJ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,221,821 - 112,222,472 (-)MPROMDB
RGD ID:6812961
Promoter ID:HG_ACW:69662
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:FYN.RAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,272,256 - 112,272,756 (-)MPROMDB
RGD ID:6803977
Promoter ID:HG_KWN:54690
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000229470,   ENST00000356013,   OTTHUMT00000043655,   OTTHUMT00000043656,   OTTHUMT00000043666
Position:
Human AssemblyChrPosition (strand)Source
Build 366112,301,186 - 112,301,962 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6q21-23.2(chr6:108944899-132067720)x1 copy number loss See cases [RCV000051196] Chr6:108944899..132067720 [GRCh38]
Chr6:109266102..132388860 [GRCh37]
Chr6:109372795..132430553 [NCBI36]
Chr6:6q21-23.2
pathogenic
NM_002037.5(FYN):c.984G>A (p.Gln328=) single nucleotide variant not provided [RCV000084661] Chr6:111696335 [GRCh38]
Chr6:112017538 [GRCh37]
Chr6:6q21
not provided
NM_002037.5(FYN):c.862+530G>A single nucleotide variant not provided [RCV000084663] Chr6:111699574 [GRCh38]
Chr6:112020777 [GRCh37]
Chr6:6q21
not provided
NM_002037.5(FYN):c.573T>C (p.Asp191=) single nucleotide variant not provided [RCV000084664] Chr6:111703009 [GRCh38]
Chr6:112024212 [GRCh37]
Chr6:6q21
not provided
NM_002037.5(FYN):c.-81-19491A>T single nucleotide variant Lung cancer [RCV000096432] Chr6:111800126 [GRCh38]
Chr6:112121329 [GRCh37]
Chr6:6q21
uncertain significance
NM_002037.5(FYN):c.1347G>A (p.Val449=) single nucleotide variant not provided [RCV000084660] Chr6:111674557 [GRCh38]
Chr6:111995760 [GRCh37]
Chr6:6q21
not provided
NM_002037.5(FYN):c.944C>G (p.Ala315Gly) single nucleotide variant not provided [RCV000084662] Chr6:111696375 [GRCh38]
Chr6:112017578 [GRCh37]
Chr6:6q21
not provided
NM_002037.5(FYN):c.333A>G (p.Ile111Met) single nucleotide variant not provided [RCV000084665] Chr6:111714358 [GRCh38]
Chr6:112035561 [GRCh37]
Chr6:6q21
not provided
GRCh38/hg38 6q21-22.1(chr6:107370141-115827482)x1 copy number loss See cases [RCV000138006] Chr6:107370141..115827482 [GRCh38]
Chr6:107691345..116148646 [GRCh37]
Chr6:107798038..116255339 [NCBI36]
Chr6:6q21-22.1
pathogenic
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3 copy number gain See cases [RCV000139729] Chr6:74382807..142040500 [GRCh38]
Chr6:75092523..142361637 [GRCh37]
Chr6:75149243..142403330 [NCBI36]
Chr6:6q13-24.1
pathogenic
GRCh38/hg38 6q16.1-22.31(chr6:96609994-122161548)x1 copy number loss See cases [RCV000139465] Chr6:96609994..122161548 [GRCh38]
Chr6:97057870..122482694 [GRCh37]
Chr6:97164591..122524393 [NCBI36]
Chr6:6q16.1-22.31
pathogenic
GRCh38/hg38 6q21-22.31(chr6:106503719-125781219)x1 copy number loss See cases [RCV000141587] Chr6:106503719..125781219 [GRCh38]
Chr6:106951594..126102365 [GRCh37]
Chr6:107058287..126144058 [NCBI36]
Chr6:6q21-22.31
pathogenic
GRCh38/hg38 6q16.3-21(chr6:103279465-113934239)x1 copy number loss See cases [RCV000142287] Chr6:103279465..113934239 [GRCh38]
Chr6:103727340..114255403 [GRCh37]
Chr6:103834033..114362096 [NCBI36]
Chr6:6q16.3-21
pathogenic
GRCh38/hg38 6q16.3-22.31(chr6:100054889-120488154)x1 copy number loss See cases [RCV000143227] Chr6:100054889..120488154 [GRCh38]
Chr6:100502765..120809300 [GRCh37]
Chr6:100609486..120850999 [NCBI36]
Chr6:6q16.3-22.31
pathogenic
GRCh37/hg19 6q21(chr6:109564793-112223595)x1 copy number loss See cases [RCV000447293] Chr6:109564793..112223595 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q21(chr6:111876945-112035699)x3 copy number gain See cases [RCV000446558] Chr6:111876945..112035699 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q14.3-22.31(chr6:85988428-120548687)x1 copy number loss See cases [RCV000445666] Chr6:85988428..120548687 [GRCh37]
Chr6:6q14.3-22.31
pathogenic
GRCh37/hg19 6q21-q22(chr6:112069445-120994664)x1 copy number loss 6q21-6q22.1 deletion [RCV000416567] Chr6:112069445..120994664 [GRCh37]
Chr6:6q21-22.31
likely pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6q16.1-22.1(chr6:95549951-116684929)x1 copy number loss not provided [RCV000682693] Chr6:95549951..116684929 [GRCh37]
Chr6:6q16.1-22.1
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
NM_002037.5(FYN):c.1120-10G>A single nucleotide variant not provided [RCV000949720] Chr6:111694538 [GRCh38]
Chr6:112015741 [GRCh37]
Chr6:6q21
benign
NM_002037.5(FYN):c.1119+8C>A single nucleotide variant not provided [RCV000949721] Chr6:111694620 [GRCh38]
Chr6:112015823 [GRCh37]
Chr6:6q21
benign
NM_002037.5(FYN):c.1273+8C>T single nucleotide variant not provided [RCV000946967] Chr6:111694367 [GRCh38]
Chr6:112015570 [GRCh37]
Chr6:6q21
benign
NM_002037.5(FYN):c.126C>T (p.Phe42=) single nucleotide variant not provided [RCV000880404] Chr6:111719926 [GRCh38]
Chr6:112041129 [GRCh37]
Chr6:6q21
benign
NM_002037.5(FYN):c.1518C>G (p.Asp506Glu) single nucleotide variant not provided [RCV000971753] Chr6:111661835 [GRCh38]
Chr6:111983038 [GRCh37]
Chr6:6q21
benign
GRCh37/hg19 6q21-22.31(chr6:110981075-119608396)x1 copy number loss not provided [RCV000848701] Chr6:110981075..119608396 [GRCh37]
Chr6:6q21-22.31
pathogenic
NM_002037.5(FYN):c.969C>T (p.His323=) single nucleotide variant not provided [RCV000886610] Chr6:111696350 [GRCh38]
Chr6:112017553 [GRCh37]
Chr6:6q21
benign
GRCh37/hg19 6q21(chr6:109564694-112232351)x1 copy number loss not provided [RCV001007557] Chr6:109564694..112232351 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q16.3-22.1(chr6:101296547-117004249)x3 copy number gain Microcephaly [RCV001251053] Chr6:101296547..117004249 [GRCh37]
Chr6:6q16.3-22.1
pathogenic
GRCh37/hg19 6q16.1-21(chr6:98949950-114533905)x1 copy number loss Deletion 6q16 q21 [RCV001263224] Chr6:98949950..114533905 [GRCh37]
Chr6:6q16.1-21
pathogenic
NM_002037.5(FYN):c.206C>G (p.Ser69Cys) single nucleotide variant Premature ovarian failure [RCV001270202] Chr6:111719846 [GRCh38]
Chr6:112041049 [GRCh37]
Chr6:6q21
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:4037 AgrOrtholog
COSMIC FYN COSMIC
Ensembl Genes ENSG00000010810 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000229471 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000346671 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000357656 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000357667 UniProtKB/Swiss-Prot
  ENSP00000357671 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000427993 UniProtKB/TrEMBL
  ENSP00000428042 UniProtKB/TrEMBL
  ENSP00000428045 UniProtKB/TrEMBL
  ENSP00000428493 UniProtKB/TrEMBL
  ENSP00000428695 UniProtKB/TrEMBL
  ENSP00000428983 UniProtKB/TrEMBL
  ENSP00000429294 UniProtKB/TrEMBL
  ENSP00000429590 UniProtKB/TrEMBL
  ENSP00000429813 UniProtKB/TrEMBL
  ENSP00000429866 UniProtKB/TrEMBL
  ENSP00000429992 UniProtKB/TrEMBL
  ENSP00000430364 UniProtKB/TrEMBL
  ENSP00000430455 UniProtKB/TrEMBL
  ENSP00000440646 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000229471 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000354650 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000368667 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000368678 UniProtKB/Swiss-Prot
  ENST00000368682 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000462598 UniProtKB/TrEMBL
  ENST00000462856 UniProtKB/TrEMBL
  ENST00000484067 UniProtKB/TrEMBL
  ENST00000487824 UniProtKB/TrEMBL
  ENST00000517419 UniProtKB/TrEMBL
  ENST00000518295 UniProtKB/TrEMBL
  ENST00000518630 UniProtKB/TrEMBL
  ENST00000520518 UniProtKB/TrEMBL
  ENST00000521062 UniProtKB/TrEMBL
  ENST00000523238 UniProtKB/TrEMBL
  ENST00000523570 UniProtKB/TrEMBL
  ENST00000523574 UniProtKB/TrEMBL
  ENST00000524310 UniProtKB/TrEMBL
  ENST00000538466 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000010810 GTEx
HGNC ID HGNC:4037 ENTREZGENE
Human Proteome Map FYN Human Proteome Map
InterPro Fyn/Yrk_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
KEGG Report hsa:2534 UniProtKB/Swiss-Prot
NCBI Gene 2534 ENTREZGENE
OMIM 137025 OMIM
Pfam Pkinase_Tyr UniProtKB/Swiss-Prot
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA28454 PharmGKB
PRINTS SH2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYRKINASE UniProtKB/Swiss-Prot
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot
UniProt E5RFM0_HUMAN UniProtKB/TrEMBL
  E5RFM4_HUMAN UniProtKB/TrEMBL
  E5RFM6_HUMAN UniProtKB/TrEMBL
  E5RFS5_HUMAN UniProtKB/TrEMBL
  E5RGM6_HUMAN UniProtKB/TrEMBL
  E5RGT0_HUMAN UniProtKB/TrEMBL
  E5RH71_HUMAN UniProtKB/TrEMBL
  E5RHF7_HUMAN UniProtKB/TrEMBL
  E5RHX7_HUMAN UniProtKB/TrEMBL
  E5RI25_HUMAN UniProtKB/TrEMBL
  E5RIX5_HUMAN UniProtKB/TrEMBL
  E5RJX7_HUMAN UniProtKB/TrEMBL
  E5RK23_HUMAN UniProtKB/TrEMBL
  FYN_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  P78484_HUMAN UniProtKB/TrEMBL
  Q14342_HUMAN UniProtKB/TrEMBL
UniProt Secondary B5BU57 UniProtKB/Swiss-Prot
  E1P557 UniProtKB/Swiss-Prot
  H0UI48 UniProtKB/Swiss-Prot
  Q16248 UniProtKB/Swiss-Prot
  Q5R3A6 UniProtKB/Swiss-Prot
  Q5R3A7 UniProtKB/Swiss-Prot
  Q8N5D7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-01 FYN  FYN proto-oncogene, Src family tyrosine kinase    FYN oncogene related to SRC, FGR, YES  Symbol and/or name change 5135510 APPROVED
2011-08-16 FYN  FYN oncogene related to SRC, FGR, YES  FYN  FYN oncogene related to SRC, FGR, YES  Symbol and/or name change 5135510 APPROVED