Dnah11 (dynein, axonemal, heavy chain 11) - Rat Genome Database
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Gene: Dnah11 (dynein, axonemal, heavy chain 11) Rattus norvegicus
Analyze
Symbol: Dnah11
Name: dynein, axonemal, heavy chain 11
RGD ID: 621088
Description: Predicted to have ATP binding activity. Predicted to be involved in several processes, including determination of left/right symmetry; flagellated sperm motility; and regulation of cilium beat frequency. Predicted to localize to 9+0 motile cilium; 9+2 motile cilium; and proximal portion of axoneme. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 7. Orthologous to human DNAH11 (dynein axonemal heavy chain 11); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: MODEL
Also known as: Dnahc11; dynein heavy chain 11, axonemal; dynein, axon, heavy chain 11; dynein, axonemal, heavy polypeptide 11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Dnah11Tn(sb-T2/Bart3)2.293Mcwi  
Genetic Models: F344-Dnah11Tn(sb-T2/Bart3)2.293Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26138,839,175 - 139,155,554 (-)NCBI
Rnor_6.0 Ensembl6145,785,275 - 146,099,053 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06145,784,893 - 146,099,212 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06154,698,519 - 155,011,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46145,190,931 - 145,516,859 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16145,376,140 - 145,389,155 (-)NCBI
Celera6136,492,481 - 136,807,626 (-)NCBICelera
Cytogenetic Map6q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Additional References at PubMed
PMID:9353118   PMID:10549278   PMID:10556073   PMID:18022865   PMID:18414654   PMID:18492703   PMID:21103351   PMID:22102620   PMID:22184204   PMID:22499950   PMID:25807483   PMID:26909801  
PMID:27340223   PMID:31178125  


Genomics

Comparative Map Data
Dnah11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26138,839,175 - 139,155,554 (-)NCBI
Rnor_6.0 Ensembl6145,785,275 - 146,099,053 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06145,784,893 - 146,099,212 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06154,698,519 - 155,011,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46145,190,931 - 145,516,859 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16145,376,140 - 145,389,155 (-)NCBI
Celera6136,492,481 - 136,807,626 (-)NCBICelera
Cytogenetic Map6q33NCBI
DNAH11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl721,543,039 - 21,901,839 (+)EnsemblGRCh38hg38GRCh38
GRCh38721,543,039 - 21,901,839 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37721,582,657 - 21,941,457 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36721,549,358 - 21,907,982 (+)NCBINCBI36hg18NCBI36
Build 34721,356,072 - 21,714,701NCBI
Celera721,568,334 - 21,927,147 (+)NCBI
Cytogenetic Map7p15.3NCBI
HuRef721,468,066 - 21,826,836 (+)NCBIHuRef
CHM1_1721,583,500 - 21,941,892 (+)NCBICHM1_1
CRA_TCAGchr7v2721,634,147 - 21,992,554 (+)NCBI
Dnah11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912117,841,717 - 118,162,778 (-)NCBIGRCm39mm39
GRCm39 Ensembl12117,841,717 - 118,162,778 (-)Ensembl
GRCm3812117,877,982 - 118,199,043 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12117,877,982 - 118,199,043 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712119,116,455 - 119,437,516 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612112,081,403 - 112,243,674 (-)NCBImm8
MGSCv3612118,322,088 - 118,643,145 (-)NCBImm8
Cytogenetic Map12F2NCBI
cM Map1263.25NCBI
Dnah11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541024,044,886 - 24,352,626 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541024,045,333 - 24,352,626 (+)NCBIChiLan1.0ChiLan1.0
DNAH11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1721,540,932 - 21,897,485 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl721,540,932 - 21,897,485 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0722,228,345 - 22,585,681 (+)NCBIMhudiblu_PPA_v0panPan3
DNAH11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1435,468,154 - 35,784,806 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11435,468,080 - 35,784,621 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dnah11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365467,370,180 - 7,681,835 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAH11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl990,423,077 - 90,767,487 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1990,420,044 - 90,768,327 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2999,840,344 - 100,218,083 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNAH11
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12136,350,606 - 36,722,018 (-)NCBI
ChlSab1.1 Ensembl2136,350,707 - 36,720,511 (-)Ensembl
Dnah11
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247398,810,127 - 9,136,044 (-)NCBI

Position Markers
D6Rat3  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.06145,868,453 - 145,868,598NCBIRnor6.0
Rnor_5.06154,781,896 - 154,782,041UniSTSRnor5.0
RGSC_v3.46145,279,292 - 145,279,437UniSTSRGSC3.4
RGSC_v3.46145,279,033 - 145,279,536RGDRGSC3.4
RGSC_v3.16145,285,479 - 145,285,624RGD
Celera6136,575,859 - 136,576,004UniSTS
RH 3.4 Map6907.6RGD
RH 3.4 Map6907.6UniSTS
RH 2.0 Map61234.2RGD
SHRSP x BN Map683.9998RGD
Cytogenetic Map6q33UniSTS
RH131860  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.06145,918,851 - 145,919,048NCBIRnor6.0
Rnor_5.06154,832,365 - 154,832,562UniSTSRnor5.0
RGSC_v3.46145,330,406 - 145,330,603UniSTSRGSC3.4
Celera6136,625,801 - 136,625,998UniSTS
RH 3.4 Map6905.1UniSTS
Cytogenetic Map6q33UniSTS
AU049492  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.06145,813,312 - 145,813,537NCBIRnor6.0
Rnor_5.06154,726,555 - 154,726,780UniSTSRnor5.0
RGSC_v3.46145,218,632 - 145,218,857UniSTSRGSC3.4
Cytogenetic Map6q33UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)6101207574147991367Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6104363890147991367Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6117355600147991367Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6127286494147249902Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6127286494147991367Rat


Genetic Models
This gene Dnah11 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:28
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000007233
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 4 7
Low 29 8 17 8 11 60 23 31 4 8
Below cutoff 3 14 30 22 2 22 12 12 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007233   ⟹   ENSRNOP00000007233
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6145,785,275 - 146,099,053 (-)Ensembl
RefSeq Acc Id: XM_001061747   ⟹   XP_001061747
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6136,492,481 - 136,807,626 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594548   ⟹   XP_017450037
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06145,784,893 - 146,099,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017603318   ⟹   XP_017458807
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6136,492,481 - 136,807,626 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017603319   ⟹   XP_017458808
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6136,492,481 - 136,807,626 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017603320   ⟹   XP_017458809
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6136,492,481 - 136,758,631 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017603321   ⟹   XP_017458810
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6136,492,481 - 136,659,915 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017603322   ⟹   XP_017458811
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6136,492,481 - 136,538,482 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078091   ⟹   XP_038934019
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 139,155,553 (-)NCBI
RefSeq Acc Id: XM_039078092   ⟹   XP_038934020
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 139,155,553 (-)NCBI
RefSeq Acc Id: XM_039078093   ⟹   XP_038934021
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 139,155,553 (-)NCBI
RefSeq Acc Id: XM_039078094   ⟹   XP_038934022
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 139,155,553 (-)NCBI
RefSeq Acc Id: XM_039078095   ⟹   XP_038934023
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 139,153,214 (-)NCBI
RefSeq Acc Id: XM_039078097   ⟹   XP_038934025
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 139,147,236 (-)NCBI
RefSeq Acc Id: XM_039078098   ⟹   XP_038934026
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,877,830 - 139,155,554 (-)NCBI
RefSeq Acc Id: XM_039078099   ⟹   XP_038934027
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 139,070,703 (-)NCBI
RefSeq Acc Id: XM_039078100   ⟹   XP_038934028
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 139,057,679 (-)NCBI
RefSeq Acc Id: XM_039078101   ⟹   XP_038934029
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 139,033,329 (-)NCBI
RefSeq Acc Id: XM_039078102   ⟹   XP_038934030
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26138,839,175 - 138,981,837 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_001061747   ⟸   XM_001061747
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017458808   ⟸   XM_017603319
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017458807   ⟸   XM_017603318
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017458809   ⟸   XM_017603320
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017458810   ⟸   XM_017603321
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017458811   ⟸   XM_017603322
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017450037   ⟸   XM_017594548
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000007233   ⟸   ENSRNOT00000007233
RefSeq Acc Id: XP_038934022   ⟸   XM_039078094
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934021   ⟸   XM_039078093
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038934020   ⟸   XM_039078092
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934019   ⟸   XM_039078091
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038934023   ⟸   XM_039078095
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038934025   ⟸   XM_039078097
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038934027   ⟸   XM_039078099
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038934028   ⟸   XM_039078100
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038934029   ⟸   XM_039078101
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038934030   ⟸   XM_039078102
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038934026   ⟸   XM_039078098
- Peptide Label: isoform X7
Protein Domains
AAA

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
6 146077864 146077865 T A snv Buf/N (MCW), F344/NRrrc (MCW), M520/N (MCW), MR/N (MCW), WKY/N (MCW), WKY/NHsd (RGD), LEW/Crl (RGD), LEW/NCrlBR (RGD), WAG/Rij (RGD), WKY/NCrl (RGD), F344/NCrl (RGD)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621088 AgrOrtholog
Ensembl Genes ENSRNOG00000005451 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000007233 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007233 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.710 UniProtKB/TrEMBL
  1.10.8.720 UniProtKB/TrEMBL
  1.20.140.100 UniProtKB/TrEMBL
  3.10.490.20 UniProtKB/TrEMBL
  3.20.180.20 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_6 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  AAA_lid_11_sf UniProtKB/TrEMBL
  DHC_D5 UniProtKB/TrEMBL
  DHC_fam UniProtKB/TrEMBL
  DNAH3_AAA_lid_1 UniProtKB/TrEMBL
  Dynein_2_C UniProtKB/TrEMBL
  Dynein_2_N UniProtKB/TrEMBL
  Dynein_AAA1S UniProtKB/TrEMBL
  Dynein_AAA5_ext UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_C_barrel UniProtKB/TrEMBL
  Dynein_HC_stalk UniProtKB/TrEMBL
  Dynein_heavy_chain_D4_dom UniProtKB/TrEMBL
  Dynein_heavy_dom UniProtKB/TrEMBL
  Dynein_heavy_dom-1 UniProtKB/TrEMBL
  Dynein_heavy_dom-2 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene 117253 ENTREZGENE
PANTHER PTHR10676 UniProtKB/TrEMBL
Pfam AAA_6 UniProtKB/TrEMBL
  AAA_8 UniProtKB/TrEMBL
  AAA_9 UniProtKB/TrEMBL
  AAA_lid_1 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  DHC_N1 UniProtKB/TrEMBL
  DHC_N2 UniProtKB/TrEMBL
  Dynein_AAA_lid UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_heavy UniProtKB/TrEMBL
  PF12777 UniProtKB/TrEMBL
PhenoGen Dnah11 PhenoGen
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
Transposagen Dnah11 Transposagen
UniProt E9PU24_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Dnah11  dynein, axonemal, heavy chain 11  Dnahc11  dynein, axonemal, heavy chain 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-10 Dnahc11  dynein, axonemal, heavy chain 11  Dnah11  dynein, axonemal, heavy chain 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Dnah11  dynein, axonemal, heavy chain 11  Dnah11  dynein, axonemal, heavy polypeptide 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Dnah11  dynein, axonemal, heavy polypeptide 11  Dnahc11  dynein, axon, heavy chain 11  Symbol and Name updated 1299863 APPROVED
2002-08-07 Dnahc11  dynein, axon, heavy chain 11      Symbol and Name status set to provisional 70820 PROVISIONAL