1. |
Quantitation of brain edema and localisation of aquaporin 4 expression in relation to susceptibility to experimental cerebral malaria. |
Ampawong S, etal., Int J Clin Exp Pathol. 2011 Aug 15;4(6):566-74. Epub 2011 Jul 23.
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2. |
Hypoalgesia in mice lacking aquaporin-4 water channels. |
Bao F, etal., Brain Res Bull. 2010 Nov 20;83(6):298-303. doi: 10.1016/j.brainresbull.2010.08.015. Epub 2010 Sep 22.
|
3. |
Changes in the astrocytic aquaporin-4 and inwardly rectifying potassium channel expression in the brain of the amyotrophic lateral sclerosis SOD1(G93A) rat model. |
Bataveljic D, etal., Glia. 2012 Dec;60(12):1991-2003. doi: 10.1002/glia.22414. Epub 2012 Sep 14.
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4. |
An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes. |
Benfenati V, etal., Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2563-8. doi: 10.1073/pnas.1012867108. Epub 2011 Jan 24.
|
5. |
Urinary concentrating defect in hypothyroid rats: role of sodium, potassium, 2-chloride co-transporter, and aquaporins. |
Cadnapaphornchai MA, etal., J Am Soc Nephrol 2003 Mar;14(3):566-74.
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6. |
[The effects of ketamine pretreated on cerebral edema and AQP4 expression after transient focal cerebral ischemia/reperfusion in rats]. |
Cai SN and Zhu SM, Zhonghua Yi Xue Za Zhi. 2010 Jun 15;90(23):1648-51.
|
7. |
Molecular analysis of aquaporin genes 1 to 4 in patients with Meniere's disease. |
Candreia C, etal., Cell Physiol Biochem. 2010;26(4-5):787-92. doi: 10.1159/000322346. Epub 2010 Oct 29.
|
8. |
Aquaporin-4 water channel expression by thymoma of patients with and without myasthenia gravis. |
Chan KH, etal., J Neuroimmunol. 2010 Oct 8;227(1-2):178-84. Epub 2010 Aug 21.
|
9. |
Novel role of aquaporin-4 in CD4+ CD25+ T regulatory cell development and severity of Parkinson's disease. |
Chi Y, etal., Aging Cell. 2011 Jun;10(3):368-82. doi: 10.1111/j.1474-9726.2011.00677.x. Epub 2011 Mar 22.
|
10. |
Age-related hearing loss: aquaporin 4 gene expression changes in the mouse cochlea and auditory midbrain. |
Christensen N, etal., Brain Res. 2009 Feb 9;1253:27-34. doi: 10.1016/j.brainres.2008.11.070. Epub 2008 Dec 3.
|
11. |
Aquaporin 4 knockdown exacerbates streptozotocin-induced diabetic retinopathy through aggravating inflammatory response. |
Cui B, etal., Exp Eye Res. 2012 May;98:37-43. doi: 10.1016/j.exer.2012.02.013. Epub 2012 Mar 16.
|
12. |
Alleviation of brain injury by applying TGN-020 in the supraoptic nucleus via inhibiting vasopressin neurons in rats of focal ischemic stroke. |
Cui D, etal., Life Sci. 2021 Jan 1;264:118683. doi: 10.1016/j.lfs.2020.118683. Epub 2020 Oct 28.
|
13. |
Anti-aquaporin-4 antibodies in the context of assorted immune-mediated diseases. |
Dellavance A, etal., Eur J Neurol. 2011 Jul 19. doi: 10.1111/j.1468-1331.2011.03479.x.
|
14. |
Changes in ocular aquaporin-4 (AQP4) expression following retinal injury. |
Dibas A, etal., Mol Vis. 2008 Sep 25;14:1770-83.
|
15. |
Changes in ocular aquaporin expression following optic nerve crush. |
Dibas A, etal., Mol Vis. 2010 Mar 3;16:330-40.
|
16. |
Brain expression of the water channels Aquaporin-1 and -4 in mice with acute liver injury, hyperammonemia and brain edema. |
Eefsen M, etal., Metab Brain Dis. 2010 Sep;25(3):315-23. Epub 2010 Oct 12.
|
17. |
Anti-aquaporin-4 IgG in Patients Presenting with Unilateral Optic Neuritis: A Cohort Study. |
Etemadifar M, etal., Int J Prev Med. 2012 Sep;3(9):612-5.
|
18. |
Altered expression of aquaporins 1 and 4 coincides with neurodegenerative events in retinas of spontaneously diabetic Torii rats. |
Fukuda M, etal., Exp Eye Res. 2010 Jan;90(1):17-25. Epub 2009 Sep 11.
|
19. |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. |
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
|
20. |
Rat ISS GO annotations from GOA human gene data--August 2006 |
GOA data from the GO Consortium
|
21. |
Temporal profiles of aquaporin 4 expression and astrocyte response in the process of brain damage in fat embolism model in rats. |
Gohara T, etal., J Anesth. 2010 Apr;24(2):225-33. Epub 2010 Jan 29.
|
22. |
Aquaporin-11: a channel protein lacking apparent transport function expressed in brain. |
Gorelick DA, etal., BMC Biochem. 2006 May 1;7:14.
|
23. |
Rapamycin alleviates brain edema after focal cerebral ischemia reperfusion in rats. |
Guo W, etal., Immunopharmacol Immunotoxicol. 2014 Jun;36(3):211-23. doi: 10.3109/08923973.2014.913616. Epub 2014 Apr 29.
|
24. |
Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. |
Hasegawa H, etal., J Biol Chem 1994 Feb 25;269(8):5497-500.
|
25. |
Variants of the genes encoding AQP4 and Kir4.1 are associated with subgroups of patients with temporal lobe epilepsy. |
Heuser K, etal., Epilepsy Res. 2010 Jan;88(1):55-64. Epub 2009 Oct 28.
|
26. |
Implications of the aquaporin-4 structure on array formation and cell adhesion. |
Hiroaki Y, etal., J Mol Biol. 2006 Jan 27;355(4):628-39. doi: 10.1016/j.jmb.2005.10.081. Epub 2005 Nov 17.
|
27. |
Retinal ectopias and mechanically weakened basement membrane in a mouse model of muscle-eye-brain (MEB) disease congenital muscular dystrophy. |
Hu H, etal., Mol Vis. 2010 Jul 28;16:1415-28.
|
28. |
The relationship between aquaporin-4 expression and blood-brain and spinal cord barrier permeability following experimental autoimmune encephalomyelitis in the rat. |
Huang XN, etal., Anat Rec (Hoboken). 2011 Jan;294(1):46-54. doi: 10.1002/ar.21286. Epub 2010 Nov 12.
|
29. |
Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema. |
Igarashi H, etal., Neurol Sci. 2011 Feb;32(1):113-6. Epub 2010 Oct 6.
|
30. |
Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere's disease and acoustic neuroma. |
Ishiyama G, etal., Cell Tissue Res. 2010 Jun;340(3):407-19. doi: 10.1007/s00441-010-0975-7. Epub 2010 May 12.
|
31. |
Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance. |
Jung JS, etal., Proc Natl Acad Sci U S A 1994 Dec 20;91(26):13052-6.
|
32. |
Aquaporin-4 water channel oligomers are associated with the transverse tubules of skeletal myofibers. |
Kaakinen M, etal., Exp Cell Res. 2011 Jan 1;317(1):20-8. Epub 2010 Sep 21.
|
33. |
Relationship between NMO-antibody and anti-MOG antibody in optic neuritis. |
Kezuka T, etal., J Neuroophthalmol. 2012 Jun;32(2):107-10. doi: 10.1097/WNO.0b013e31823c9b6c.
|
34. |
Decreased hemispheric Aquaporin-4 is linked to evolving brain edema following controlled cortical impact injury in rats. |
Kiening KL, etal., Neurosci Lett 2002 May 17;324(2):105-8.
|
35. |
Astroglial loss and edema formation in the rat piriform cortex and hippocampus following pilocarpine-induced status epilepticus. |
Kim JE, etal., J Comp Neurol. 2010 Nov 15;518(22):4612-28.
|
36. |
Protective role of aquaporin-4 water channels after contusion spinal cord injury. |
Kimura A, etal., Ann Neurol. 2010 Jun;67(6):794-801.
|
37. |
Longitudinally extensive transverse myelitis with and without aquaporin 4 antibodies. |
Kitley J, etal., JAMA Neurol. 2013 Nov;70(11):1375-81. doi: 10.1001/jamaneurol.2013.3890.
|
38. |
High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. |
Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
|
39. |
Aquaporins in the kidney. |
Kwon TH, etal., Handb Exp Pharmacol. 2009;(190):95-132. doi: 10.1007/978-3-540-79885-9_5.
|
40. |
Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis. |
Lee DJ, etal., Exp Neurol. 2012 May;235(1):246-55. doi: 10.1016/j.expneurol.2012.02.002. Epub 2012 Feb 14.
|
41. |
IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. |
Lennon VA, etal., J Exp Med. 2005 Aug 15;202(4):473-7. Epub 2005 Aug 8.
|
42. |
Downregulation of renal aquaporins in response to unilateral ureteral obstruction. |
Li C, etal., Am J Physiol Renal Physiol 2003 May;284(5):F1066-79.
|
43. |
Impaired hearing in mice lacking aquaporin-4 water channels. |
Li J and Verkman AS, J Biol Chem 2001 Aug 17;276(33):31233-7. Epub 2001 Jun 13.
|
44. |
Greatly attenuated experimental autoimmune encephalomyelitis in aquaporin-4 knockout mice. |
Li L, etal., BMC Neurosci. 2009 Aug 6;10:94.
|
45. |
[A aquaporin 4 expression and effects in rat hippocampus after microwave radiation]. |
Li X, etal., Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2009 Sep;27(9):534-8.
|
46. |
The Involvement of Aquaporin-4 in the Interstitial Fluid Drainage Impairment Following Subarachnoid Hemorrhage. |
Liu E, etal., Front Aging Neurosci. 2021 Jan 26;12:611494. doi: 10.3389/fnagi.2020.611494. eCollection 2020.
|
47. |
Arginine-vasopressin V1 but not V2 receptor antagonism modulates infarct volume, brain water content, and aquaporin-4 expression following experimental stroke. |
Liu X, etal., Neurocrit Care. 2010 Feb;12(1):124-31.
|
48. |
Calcitonin gene-related peptide prevents blood-brain barrier injury and brain edema induced by focal cerebral ischemia reperfusion. |
Liu Z, etal., Regul Pept. 2011 Nov 10;171(1-3):19-25. Epub 2011 Jun 28.
|
49. |
[The effect of AQP4 gene on the activation of retinal glial cells in chronic high intraocular pressure mice]. |
Luo SS, etal., Zhonghua Yan Ke Za Zhi. 2012 Jul;48(7):598-603.
|
50. |
Preliminary study on the association of AQP4 promoter polymorphism with anti-aquaporin-4 antibody positivity in southern Han Chinese patients with idiopathic demyelinating disorders of central nervous system. |
Mai W, etal., J Neuroimmunol. 2013 Feb 15;255(1-2):75-80. doi: 10.1016/j.jneuroim.2012.10.004. Epub 2012 Oct 29.
|
51. |
Sulphoraphane enhances aquaporin-4 expression and decreases spinal cord oedema following spinal cord injury. |
Mao L, etal., Brain Inj. 2011;25(3):300-6. Epub 2011 Jan 31.
|
52. |
Aquaporin 4 regulation during acute and long-term experimental Herpes simplex virus encephalitis. |
Martinez Torres FJ, etal., J Neurovirol. 2007;13(1):38-46.
|
53. |
Aquaporin-4 astrocytopathy in Balo's disease. |
Matsuoka T, etal., Acta Neuropathol. 2010 Nov;120(5):651-60. Epub 2010 Aug 3.
|
54. |
Rat ISS GO annotations from MGI mouse gene data--August 2006 |
MGD data from the GO Consortium
|
55. |
Aquaporin expression in the brains of patients with or without cerebral amyloid angiopathy. |
Moftakhar P, etal., J Neuropathol Exp Neurol. 2010 Dec;69(12):1201-9.
|
56. |
Aquaporin expression in blood-retinal barrier cells during experimental autoimmune uveitis. |
Motulsky E, etal., Mol Vis. 2010 Apr 3;16:602-10.
|
57. |
Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG. |
Musa-Aziz R, etal., Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5406-11. doi: 10.1073/pnas.0813231106. Epub 2009 Mar 9.
|
58. |
Electronic Transfer of LocusLink and RefSeq Data |
NCBI rat LocusLink and RefSeq merged data July 26, 2002
|
59. |
Compensatory increase in AQP2, p-AQP2, and AQP3 expression in rats with diabetes mellitus. |
Nejsum LN, etal., Am J Physiol Renal Physiol 2001 Apr;280(4):F715-26.
|
60. |
Functional requirement of aquaporin-5 in plasma membranes of sweat glands. |
Nejsum LN, etal., Proc Natl Acad Sci U S A 2002 Jan 8;99(1):511-516.
|
61. |
Transcriptional profiling of spinal cord injury-induced central neuropathic pain. |
Nesic O, etal., J Neurochem. 2005 Nov;95(4):998-1014. Epub 2005 Oct 10.
|
62. |
Aquaporin 1 - a novel player in spinal cord injury. |
Nesic O, etal., J Neurochem. 2008 May;105(3):628-40. Epub 2008 Jan 28.
|
63. |
Aquaporin-4 overexpression in rat ALS model. |
Nicaise C, etal., Anat Rec (Hoboken). 2009 Feb;292(2):207-13.
|
64. |
Higher order structure of aquaporin-4. |
Nicchia GP, etal., Neuroscience. 2010 Jul 28;168(4):903-14. Epub 2010 Feb 11.
|
65. |
Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis. |
Papadopoulos MC and Verkman AS, J Biol Chem. 2005 Apr 8;280(14):13906-12. Epub 2005 Feb 4.
|
66. |
Expression of aquaporin 1 and 4 in a congenital hydrocephalus rat model. |
Paul L, etal., Neurosurgery. 2011 Feb;68(2):462-73.
|
67. |
Experimental autoimmune encephalomyelitis (EAE) IN C57Bl/6 mice is not associated with astrogliosis. |
Pham H, etal., J Neuroimmunol. 2011 Mar;232(1-2):51-62. Epub 2010 Nov 6.
|
68. |
KEGG Annotation Import Pipeline |
Pipeline to import KEGG annotations from KEGG into RGD
|
69. |
Evidence of aquaporin involvement in human central pontine myelinolysis. |
Popescu BF, etal., Acta Neuropathol Commun. 2013 Jul 25;1(1):40. doi: 10.1186/2051-5960-1-40.
|
70. |
Loss of AQP4 polarized localization with loss of beta-dystroglycan immunoreactivity may induce brain edema following intracerebral hemorrhage. |
Qiu GP, etal., Neurosci Lett. 2015 Feb 19;588:42-8. doi: 10.1016/j.neulet.2014.12.053. Epub 2014 Dec 27.
|
71. |
Brain aquaporin-4 in experimental acute liver failure. |
Rama Rao KV, etal., J Neuropathol Exp Neurol. 2010 Sep;69(9):869-79.
|
72. |
Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica. |
Ratelade J, etal., Acta Neuropathol. 2013 Nov;126(5):699-709. doi: 10.1007/s00401-013-1172-z. Epub 2013 Aug 31.
|
73. |
Effects of intravitreal triamcinolone acetonide on retinal gene expression in a rat model of central retinal vein occlusion. |
Rehak M, etal., Graefes Arch Clin Exp Ophthalmol. 2011 Aug;249(8):1175-83. Epub 2011 Apr 13.
|
74. |
Data Import for Chemical-Gene Interactions |
RGD automated import pipeline for gene-chemical interactions
|
75. |
Supramolecular aggregation of aquaporin-4 is different in muscle and brain: correlation with tissue susceptibility in neuromyelitis optica. |
Rosito S, etal., J Cell Mol Med. 2018 Feb;22(2):1236-1246. doi: 10.1111/jcmm.13401. Epub 2017 Oct 20.
|
76. |
Effects of estradiol on ischemic factor-induced astrocyte swelling and AQP4 protein abundance. |
Rutkowsky JM, etal., Am J Physiol Cell Physiol. 2011 Jul;301(1):C204-12. Epub 2011 Apr 6.
|
77. |
Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. |
Saadoun S, etal., Brain. 2010 Feb;133(Pt 2):349-61. Epub 2010 Jan 4.
|
78. |
[Deficiency of water channel AQP4 aggravates NMDA-induced brain injury in mice]. |
Shi WZ, etal., Zhejiang Da Xue Xue Bao Yi Xue Ban. 2011 Mar;40(2):145-9.
|
79. |
Expression of aquaporin 1 and aquaporin 4 water channels in rat choroid plexus. |
Speake T, etal., Biochim Biophys Acta 2003 Jan 10;1609(1):80-6.
|
80. |
Intractable hiccup and nausea in neuromyelitis optica with anti-aquaporin-4 antibody: a herald of acute exacerbations. |
Takahashi T, etal., J Neurol Neurosurg Psychiatry. 2008 Sep;79(9):1075-8. doi: 10.1136/jnnp.2008.145391. Epub 2008 Apr 17.
|
81. |
Select types of supporting cell in the inner ear express aquaporin-4 water channel protein. |
Takumi Y, etal., Eur J Neurosci. 1998 Dec;10(12):3584-95.
|
82. |
Anti-aquaporin 4 antibody in selected Japanese multiple sclerosis patients with long spinal cord lesions. |
Tanaka K, etal., Mult Scler. 2007 Aug;13(7):850-5. Epub 2007 Apr 27.
|
83. |
Anti-aquaporin 4 antibody in Japanese multiple sclerosis: the presence of optic spinal multiple sclerosis without long spinal cord lesions and anti-aquaporin 4 antibody. |
Tanaka M, etal., J Neurol Neurosurg Psychiatry. 2007 Sep;78(9):990-2.
|
84. |
Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema. |
Thrane AS, etal., Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):846-51. Epub 2010 Dec 27.
|
85. |
[Changes of VEGF and AQPs gene and protein expression in rat brain tissue during hypoxic encephaledema]. |
Tian YM, etal., Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2011 Feb;27(1):7-11.
|
86. |
Expression of aquaporins 1 and 4 in the brain of spontaneously hypertensive rats. |
Tomassoni D, etal., Brain Res. 2010 Apr 14;1325:155-63. Epub 2010 Feb 12.
|
87. |
Effect of decompressive craniectomy on aquaporin-4 expression after lateral fluid percussion injury in rats. |
Tomura S, etal., J Neurotrauma. 2011 Feb;28(2):237-43.
|
88. |
Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. |
Tradtrantip L, etal., Ann Neurol. 2012 Mar;71(3):314-22. doi: 10.1002/ana.22657. Epub 2012 Jan 23.
|
89. |
Beneficial effect of agmatine on brain apoptosis, astrogliosis, and edema after rat transient cerebral ischemia. |
Wang CC, etal., BMC Pharmacol. 2010 Sep 6;10:11. doi: 10.1186/1471-2210-10-11.
|
90. |
2-Methoxyestradiol inhibits the up-regulation of AQP4 and AQP1 expression after spinal cord injury. |
Wang YF, etal., Brain Res. 2011 Jan 25;1370:220-6. Epub 2010 Nov 16.
|
91. |
Regional expression of aquaporin 1, 4, and 9 in the brain during pregnancy. |
Wiegman MJ, etal., Reprod Sci. 2008 May;15(5):506-16.
|
92. |
Role of aquaporin-4 in the development of brain oedema in liver failure. |
Wright G, etal., J Hepatol. 2010 Jul;53(1):91-7. Epub 2010 Apr 1.
|
93. |
Time course of upregulation of inflammatory mediators in the hemorrhagic brain in rats: correlation with brain edema. |
Wu H, etal., Neurochem Int. 2010 Oct;57(3):248-53. Epub 2010 Jun 10.
|
94. |
Myelin oligodendrocyte glycoprotein induces aquaporin-4 autoantibodies in mouse experimental autoimmune encephalomyelitis. |
Wu X, etal., J Neuroimmunol. 2013 Aug 15;261(1-2):1-6. doi: 10.1016/j.jneuroim.2013.03.008. Epub 2013 May 22.
|
95. |
Water permeability and characterization of aquaporin-11. |
Yakata K, etal., J Struct Biol. 2011 May;174(2):315-20. doi: 10.1016/j.jsb.2011.01.003. Epub 2011 Jan 18.
|
96. |
Clinical features and sera anti-aquaporin 4 antibody positivity in patients with demyelinating disorders of the central nervous system from Tianjin, China. |
Yang CS, etal., CNS Neurosci Ther. 2014 Jan;20(1):32-9. doi: 10.1111/cns.12156. Epub 2013 Jul 27.
|
97. |
Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia. |
Yang M, etal., Brain Res. 2009 Sep 22;1290:121-32. Epub 2009 Jul 16.
|
98. |
Differential Regulations of AQP4 and Kir4.1 by Triamcinolone Acetonide and Dexamethasone in the Healthy and Inflamed Retina. |
Zhao M, etal., Invest Ophthalmol Vis Sci. 2011 Aug 11;52(9):6340-7. Print 2011 Sep.
|
99. |
Favorable effects of MMP-9 knockdown in murine herpes simplex encephalitis using small interfering RNA. |
Zhou Y, etal., Neurol Res. 2010 Oct;32(8):801-9. doi: 10.1179/016164110X12644252260556. Epub 2010 May 18.
|