Aqp4 (aquaporin 4) - Rat Genome Database

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Gene: Aqp4 (aquaporin 4) Mus musculus
Analyze
Symbol: Aqp4
Name: aquaporin 4
RGD ID: 10183
MGI Page MGI
Description: Enables water channel activity. Involved in several processes, including cellular water homeostasis; cerebrospinal fluid circulation; and cerebrospinal fluid secretion. Acts upstream of or within renal water absorption and sensory perception of sound. Located in several cellular components, including astrocyte end-foot; basolateral plasma membrane; and sarcolemma. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; mammary gland; metanephros; and nasal cavity. Used to study malaria. Human ortholog(s) of this gene implicated in Meniere's disease; blindness; optic nerve disease (multiple); temporal lobe epilepsy; and transverse myelitis. Orthologous to human AQP4 (aquaporin 4).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AQP-4; aqua; aquaporin-4; mercurial-insensitive water channel; WCH4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391815,522,451 - 15,544,039 (-)NCBIGRCm39mm39
GRCm39 Ensembl1815,522,553 - 15,544,039 (-)Ensembl
GRCm381815,389,394 - 15,410,982 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1815,389,496 - 15,410,982 (-)EnsemblGRCm38mm10GRCm38
MGSCv371815,547,903 - 15,562,193 (-)NCBIGRCm37mm9NCBIm37
MGSCv361815,535,839 - 15,546,671 (-)NCBImm8
Celera1815,609,213 - 15,623,487 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map188.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(S)-nicotine  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP,ISO)
1,3-dinitrobenzene  (ISO)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxy-17beta-estradiol  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP,ISO)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (ISO)
acetic acid  (ISO)
acrylamide  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP)
alpha-D-galactose  (EXP)
ammonia  (ISO)
ammonium chloride  (ISO)
arsenous acid  (ISO)
benazepril  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[ghi]perylene  (EXP)
betamethasone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
calcidiol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
clofibrate  (EXP)
Cuprizon  (ISO)
cycloheximide  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
desferrioxamine B  (ISO)
Diallyl sulfide  (EXP)
diarsenic trioxide  (ISO)
diprotium oxide  (EXP,ISO)
doxorubicin  (ISO)
ethanol  (EXP,ISO)
folic acid  (EXP)
furan  (ISO)
galactose  (EXP)
gentamycin  (EXP,ISO)
glucose  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen chloride  (ISO)
iron atom  (EXP,ISO)
iron dichloride  (EXP)
iron(0)  (EXP,ISO)
iron(III) citrate  (ISO)
L-methionine  (EXP)
lansoprazole  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
mercury dichloride  (ISO)
methylmercury chloride  (ISO)
morphine  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nicotine  (EXP)
nitrofen  (ISO)
O-methyleugenol  (ISO)
olanzapine  (ISO)
ozone  (ISO)
palmitoyl ethanolamide  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
phenobarbital  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
rac-lactic acid  (ISO)
reactive oxygen species  (EXP)
rifampicin  (ISO)
SB 203580  (EXP)
SB-239063  (ISO)
Soman  (ISO)
sulforaphane  (EXP)
terbutaline  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (EXP)
thalidomide  (EXP)
thioacetamide  (ISO)
thiourea  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
triazines  (EXP)
trichostatin A  (ISO)
Triptolide  (EXP)
valproic acid  (ISO)
valsartan  (ISO)
vinclozolin  (ISO)
vitamin E  (EXP,ISO)
water  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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41. MGD and Homologene mouse data transfer
42. MGD data from the GO Consortium
43. MGD IEA
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Additional References at PubMed
PMID:8660998   PMID:8889548   PMID:9143504   PMID:9276712   PMID:9325187   PMID:9427293   PMID:9486146   PMID:9757370   PMID:9822113   PMID:9886922   PMID:10021464   PMID:10232700  
PMID:10349636   PMID:10400615   PMID:10613915   PMID:10655103   PMID:10662735   PMID:10673041   PMID:10737773   PMID:10788316   PMID:10795927   PMID:10837338   PMID:10856128   PMID:10870513  
PMID:10915655   PMID:10915657   PMID:10960499   PMID:11042159   PMID:11066060   PMID:11076861   PMID:11217851   PMID:11331305   PMID:11382807   PMID:11514581   PMID:11726686   PMID:11741725  
PMID:12031518   PMID:12034763   PMID:12232046   PMID:12233788   PMID:12359252   PMID:12477932   PMID:12565800   PMID:12578959   PMID:12673830   PMID:14576087   PMID:14597704   PMID:14734638  
PMID:15003543   PMID:15033928   PMID:15076748   PMID:15120852   PMID:15149973   PMID:15208268   PMID:15371505   PMID:15489334   PMID:15557457   PMID:15561413   PMID:15789430   PMID:15898955  
PMID:16079275   PMID:16103109   PMID:16141072   PMID:16141073   PMID:16181429   PMID:16203098   PMID:16237719   PMID:16303850   PMID:16470808   PMID:16511868   PMID:16564496   PMID:16582023  
PMID:16602821   PMID:16618389   PMID:16624821   PMID:16797122   PMID:16871401   PMID:16938871   PMID:17074507   PMID:17196551   PMID:17349777   PMID:17353068   PMID:17377981   PMID:17437301  
PMID:17525153   PMID:17611025   PMID:17868659   PMID:17869537   PMID:18057022   PMID:18281883   PMID:18284610   PMID:18286643   PMID:18328627   PMID:18338794   PMID:18375385   PMID:18495879  
PMID:18510734   PMID:18511552   PMID:18572411   PMID:18679005   PMID:18708067   PMID:18718702   PMID:18951529   PMID:18973795   PMID:18976758   PMID:18985050   PMID:19033383   PMID:19046364  
PMID:19203409   PMID:19237298   PMID:19258494   PMID:19303428   PMID:19345723   PMID:19367412   PMID:19373938   PMID:19393298   PMID:19416500   PMID:19428702   PMID:19429174   PMID:19449033  
PMID:19450458   PMID:19743445   PMID:19761816   PMID:19843522   PMID:19855135   PMID:19906978   PMID:20121927   PMID:20132816   PMID:20132873   PMID:20153404   PMID:20364088   PMID:20387009  
PMID:20437101   PMID:20544823   PMID:20818388   PMID:20877385   PMID:20944625   PMID:21151500   PMID:21178974   PMID:21212277   PMID:21256195   PMID:21257712   PMID:21262839   PMID:21264240  
PMID:21267068   PMID:21281561   PMID:21283711   PMID:21285396   PMID:21339176   PMID:21446052   PMID:21491501   PMID:21525279   PMID:21552523   PMID:21677750   PMID:21705333   PMID:21721139  
PMID:21873635   PMID:21990350   PMID:22020118   PMID:22069320   PMID:22076159   PMID:22128336   PMID:22131281   PMID:22173850   PMID:22193336   PMID:22233890   PMID:22237799   PMID:22365952  
PMID:22378467   PMID:22394609   PMID:22419561   PMID:22473056   PMID:22526022   PMID:22533723   PMID:22590566   PMID:22634625   PMID:22718347   PMID:22777185   PMID:22820194   PMID:22896675  
PMID:22991445   PMID:23032072   PMID:23051665   PMID:23126383   PMID:23132680   PMID:23180003   PMID:23277579   PMID:23346911   PMID:23428384   PMID:23443171   PMID:23485789   PMID:23520529  
PMID:23563310   PMID:23611872   PMID:23805198   PMID:23935196   PMID:24014171   PMID:24154525   PMID:24165567   PMID:24174672   PMID:24186965   PMID:24231830   PMID:24321433   PMID:24355496  
PMID:24368741   PMID:24390474   PMID:24422972   PMID:24515349   PMID:24717641   PMID:24744149   PMID:24792367   PMID:24915007   PMID:24952082   PMID:24952961   PMID:24978642   PMID:25013167  
PMID:25100404   PMID:25124666   PMID:25128605   PMID:25160756   PMID:25174305   PMID:25359421   PMID:25382142   PMID:25449874   PMID:25471560   PMID:25604731   PMID:25790314   PMID:25944186  
PMID:25990016   PMID:26039099   PMID:26120030   PMID:26126866   PMID:26287441   PMID:26424896   PMID:26489685   PMID:26526066   PMID:26748031   PMID:26760501   PMID:26774050   PMID:26847765  
PMID:26884844   PMID:26946517   PMID:27018215   PMID:27038751   PMID:27155358   PMID:27373674   PMID:27581370   PMID:27629271   PMID:27751903   PMID:27789520   PMID:27837334   PMID:27940915  
PMID:28058717   PMID:28078912   PMID:28215940   PMID:28222512   PMID:28317216   PMID:28365776   PMID:28402976   PMID:28427055   PMID:28461494   PMID:28551776   PMID:28627708   PMID:28645746  
PMID:28735099   PMID:28822114   PMID:28826498   PMID:28906027   PMID:28929580   PMID:28940930   PMID:29055082   PMID:29106906   PMID:29125630   PMID:29153303   PMID:29154923   PMID:29237740  
PMID:29565042   PMID:29600800   PMID:29608911   PMID:29793504   PMID:29869011   PMID:29956748   PMID:30293570   PMID:30347264   PMID:30557661   PMID:30561329   PMID:30607477   PMID:30628716  
PMID:30635555   PMID:30650354   PMID:30680924   PMID:30738082   PMID:30791140   PMID:30809535   PMID:30813473   PMID:30877104   PMID:30889310   PMID:31034776   PMID:31078684   PMID:31092872  
PMID:31097598   PMID:31190144   PMID:31220136   PMID:31364823   PMID:31644276   PMID:31709761   PMID:31814527   PMID:31927062   PMID:32033173   PMID:32046059   PMID:32102323   PMID:32133736  
PMID:32138732   PMID:32178707   PMID:32213628   PMID:32325033   PMID:32398151   PMID:32484924   PMID:32613467   PMID:32623691   PMID:32681852   PMID:32783141   PMID:32790044   PMID:32976770  
PMID:32998402   PMID:33130678   PMID:33167342   PMID:33316302   PMID:33474763   PMID:33529207   PMID:33599736   PMID:33624776   PMID:33651262   PMID:34575909  


Genomics

Comparative Map Data
Aqp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391815,522,451 - 15,544,039 (-)NCBIGRCm39mm39
GRCm39 Ensembl1815,522,553 - 15,544,039 (-)Ensembl
GRCm381815,389,394 - 15,410,982 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1815,389,496 - 15,410,982 (-)EnsemblGRCm38mm10GRCm38
MGSCv371815,547,903 - 15,562,193 (-)NCBIGRCm37mm9NCBIm37
MGSCv361815,535,839 - 15,546,671 (-)NCBImm8
Celera1815,609,213 - 15,623,487 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map188.74NCBI
AQP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1826,852,043 - 26,865,771 (-)EnsemblGRCh38hg38GRCh38
GRCh381826,852,038 - 26,865,803 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371824,432,002 - 24,445,767 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361822,686,005 - 22,699,714 (-)NCBINCBI36hg18NCBI36
Build 341822,686,007 - 22,699,714NCBI
Celera1821,242,174 - 21,255,883 (-)NCBI
Cytogenetic Map18q11.2NCBI
HuRef1821,281,696 - 21,295,401 (-)NCBIHuRef
CHM1_11824,359,750 - 24,373,454 (-)NCBICHM1_1
Aqp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2186,507,903 - 6,524,558 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl186,507,903 - 6,524,856 (-)Ensembl
Rnor_6.0186,766,009 - 6,782,757 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl186,765,945 - 6,782,996 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0186,720,759 - 6,737,703 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,626,313 - 6,642,766 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1186,628,189 - 6,642,700 (-)NCBI
Celera186,530,014 - 6,546,446 (-)NCBICelera
RH 3.4 Map1886.21RGD
RH 3.4 Map1878.3RGD
Cytogenetic Map18p13NCBI
Aqp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049557721,159 - 10,709 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049557721,160 - 10,709 (+)NCBIChiLan1.0ChiLan1.0
AQP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11823,713,141 - 23,726,919 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1823,713,146 - 23,726,919 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01820,108,607 - 20,122,381 (-)NCBIMhudiblu_PPA_v0panPan3
AQP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1761,855,617 - 61,868,953 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl761,855,744 - 61,865,089 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha761,290,817 - 61,304,150 (+)NCBI
ROS_Cfam_1.0761,906,422 - 61,919,761 (+)NCBI
UMICH_Zoey_3.1761,579,168 - 61,592,459 (+)NCBI
UNSW_CanFamBas_1.0761,591,530 - 61,604,873 (+)NCBI
UU_Cfam_GSD_1.0761,894,861 - 61,908,198 (+)NCBI
Aqp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494457,872,160 - 57,884,958 (+)NCBI
SpeTri2.0NW_0049365505,931,201 - 5,943,999 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AQP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6111,400,794 - 111,422,042 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16111,407,632 - 111,422,169 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26104,387,592 - 104,394,409 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AQP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11853,729,143 - 53,742,916 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1853,729,186 - 53,743,156 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605028,456,973 - 28,470,756 (+)NCBIVero_WHO_p1.0
Aqp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247705,581,192 - 5,593,470 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Aqp4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381815,399,594 - 15,399,824UniSTSGRCm38
MGSCv371815,558,103 - 15,558,333UniSTSGRCm37
Celera1815,619,401 - 15,619,631UniSTS
Cytogenetic Map18A1UniSTS
cM Map186.0UniSTS
cM Map186.0UniSTS
Aqp4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381815,392,844 - 15,393,397UniSTSGRCm38
MGSCv371815,551,353 - 15,551,906UniSTSGRCm37
Celera1815,612,663 - 15,613,216UniSTS
Cytogenetic Map18A1UniSTS
cM Map186.0UniSTS
Aqp4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map18A1UniSTS
cM Map186.0UniSTS
Aqp4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map18A1UniSTS
cM Map186.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961139571Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181389696666965891Mouse
1558873Hrtfm7_mheart failure modifier 7 (mouse)Not determined18795390741954049Mouse
4142127Rafaril_mRafar interacting locus (mouse)Not determined18123108555Mouse
4142250Idd21.3_minsulin dependent diabetes susceptibility 21.3 (mouse)Not determined18610840421513420Mouse
13207589Mwmlpa3_mMorris water maze latency to platform, all, 3 (mouse)18133414682Mouse
13207585Mwmlpt3_mMorris water maze latency to platform, training, 3 (mouse)18133414682Mouse
12801462Intim3_mintima modifier 3 (mouse)18131587699Mouse
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060800000Mouse
13504732Cath6_mcarotid atherosclerosis 6 (mouse)181350407347504073Mouse
14928307Manh83_mmandible shape 83 (mouse)18126902168Mouse
12801458Intmrm3_mintima/media ratio modifier 3 (mouse)18131587699Mouse
11354953Mom21_mmodifier of Min 21 (mouse)18128760766Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1051
Count of miRNA genes:614
Interacting mature miRNAs:735
Transcripts:ENSMUST00000079081
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001317729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC133525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF219992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF469168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF469169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY484964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY484965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY484966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY728055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY803942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY803943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY803944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB195919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB628835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB750519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX633380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD803766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U33012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U48397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U48398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U48399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U48400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000079081   ⟹   ENSMUSP00000078088
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,522,553 - 15,536,815 (-)Ensembl
GRCm38.p6 Ensembl1815,389,496 - 15,403,758 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234053   ⟹   ENSMUSP00000157337
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,526,448 - 15,544,039 (-)Ensembl
GRCm38.p6 Ensembl1815,393,391 - 15,410,982 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234140
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,530,250 - 15,533,059 (-)Ensembl
GRCm38.p6 Ensembl1815,397,193 - 15,400,002 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234391   ⟹   ENSMUSP00000157347
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,526,447 - 15,544,039 (-)Ensembl
GRCm38.p6 Ensembl1815,393,390 - 15,410,982 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234466   ⟹   ENSMUSP00000157324
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,526,447 - 15,541,145 (-)Ensembl
GRCm38.p6 Ensembl1815,393,390 - 15,408,088 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234473   ⟹   ENSMUSP00000157152
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,526,448 - 15,544,039 (-)Ensembl
GRCm38.p6 Ensembl1815,393,391 - 15,410,982 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234518   ⟹   ENSMUSP00000157239
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,526,447 - 15,544,039 (-)Ensembl
GRCm38.p6 Ensembl1815,393,390 - 15,410,982 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234533   ⟹   ENSMUSP00000157261
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,526,527 - 15,543,986 (-)Ensembl
GRCm38.p6 Ensembl1815,393,470 - 15,410,929 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234624
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,526,447 - 15,542,551 (-)Ensembl
GRCm38.p6 Ensembl1815,393,390 - 15,409,494 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234643   ⟹   ENSMUSP00000157060
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,526,501 - 15,536,056 (-)Ensembl
GRCm38.p6 Ensembl1815,393,444 - 15,402,999 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235044   ⟹   ENSMUSP00000157000
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,526,447 - 15,544,039 (-)Ensembl
GRCm38.p6 Ensembl1815,393,390 - 15,410,982 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238946   ⟹   ENSMUSP00000159185
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1815,522,553 - 15,533,059 (-)Ensembl
GRCm38.p6 Ensembl1815,389,496 - 15,400,002 (-)Ensembl
RefSeq Acc Id: NM_001308641   ⟹   NP_001295570
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391815,522,451 - 15,544,039 (-)NCBI
GRCm381815,389,394 - 15,410,982 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308642   ⟹   NP_001295571
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391815,522,451 - 15,544,039 (-)NCBI
GRCm381815,389,394 - 15,410,982 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308643   ⟹   NP_001295572
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391815,522,451 - 15,544,039 (-)NCBI
GRCm381815,389,394 - 15,410,982 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308644   ⟹   NP_001295573
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391815,522,451 - 15,544,039 (-)NCBI
GRCm381815,389,394 - 15,410,982 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308645   ⟹   NP_001295574
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391815,522,451 - 15,544,039 (-)NCBI
GRCm381815,389,394 - 15,410,982 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308646   ⟹   NP_001295575
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391815,522,451 - 15,544,039 (-)NCBI
GRCm381815,389,394 - 15,410,982 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308647   ⟹   NP_001295576
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391815,522,451 - 15,536,056 (-)NCBI
GRCm381815,389,394 - 15,402,999 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001317729   ⟹   NP_001304658
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391815,522,451 - 15,536,815 (-)NCBI
GRCm381815,389,394 - 15,403,758 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009700   ⟹   NP_033830
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391815,522,451 - 15,536,815 (-)NCBI
GRCm381815,389,394 - 15,403,758 (-)NCBI
MGSCv371815,547,903 - 15,562,193 (-)RGD
Celera1815,609,213 - 15,623,487 (-)RGD
cM Map18 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001295570 (Get FASTA)   NCBI Sequence Viewer  
  NP_001295571 (Get FASTA)   NCBI Sequence Viewer  
  NP_001295572 (Get FASTA)   NCBI Sequence Viewer  
  NP_001295573 (Get FASTA)   NCBI Sequence Viewer  
  NP_001295574 (Get FASTA)   NCBI Sequence Viewer  
  NP_001295575 (Get FASTA)   NCBI Sequence Viewer  
  NP_001295576 (Get FASTA)   NCBI Sequence Viewer  
  NP_001304658 (Get FASTA)   NCBI Sequence Viewer  
  NP_033830 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA84923 (Get FASTA)   NCBI Sequence Viewer  
  AAB41568 (Get FASTA)   NCBI Sequence Viewer  
  AAB41569 (Get FASTA)   NCBI Sequence Viewer  
  AAB41570 (Get FASTA)   NCBI Sequence Viewer  
  AAB41571 (Get FASTA)   NCBI Sequence Viewer  
  AAC53155 (Get FASTA)   NCBI Sequence Viewer  
  AAG44243 (Get FASTA)   NCBI Sequence Viewer  
  AAH24526 (Get FASTA)   NCBI Sequence Viewer  
  AAL73545 (Get FASTA)   NCBI Sequence Viewer  
  AAL73546 (Get FASTA)   NCBI Sequence Viewer  
  AAM81576 (Get FASTA)   NCBI Sequence Viewer  
  AAS21131 (Get FASTA)   NCBI Sequence Viewer  
  AAS21132 (Get FASTA)   NCBI Sequence Viewer  
  AAS21133 (Get FASTA)   NCBI Sequence Viewer  
  AAX07194 (Get FASTA)   NCBI Sequence Viewer  
  AAX07195 (Get FASTA)   NCBI Sequence Viewer  
  AAX07196 (Get FASTA)   NCBI Sequence Viewer  
  AAX31139 (Get FASTA)   NCBI Sequence Viewer  
  AAX31140 (Get FASTA)   NCBI Sequence Viewer  
  AAX31141 (Get FASTA)   NCBI Sequence Viewer  
  BAC32325 (Get FASTA)   NCBI Sequence Viewer  
  BAE43321 (Get FASTA)   NCBI Sequence Viewer  
  CAJ18569 (Get FASTA)   NCBI Sequence Viewer  
  EDL01600 (Get FASTA)   NCBI Sequence Viewer  
  EDL01601 (Get FASTA)   NCBI Sequence Viewer  
  EDL01602 (Get FASTA)   NCBI Sequence Viewer  
  P55088 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_033830   ⟸   NM_009700
- Peptide Label: isoform M1
- UniProtKB: P55088 (UniProtKB/Swiss-Prot),   A0A0R4J0Z3 (UniProtKB/TrEMBL),   Q8BR89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295570   ⟸   NM_001308641
- Peptide Label: isoform M23
- UniProtKB: P55088 (UniProtKB/Swiss-Prot),   Q50H70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295571   ⟸   NM_001308642
- Peptide Label: isoform M23
- UniProtKB: P55088 (UniProtKB/Swiss-Prot),   Q50H70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295573   ⟸   NM_001308644
- Peptide Label: isoform M23
- UniProtKB: P55088 (UniProtKB/Swiss-Prot),   Q50H70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295572   ⟸   NM_001308643
- Peptide Label: isoform M23
- UniProtKB: P55088 (UniProtKB/Swiss-Prot),   Q50H70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295574   ⟸   NM_001308645
- Peptide Label: isoform M23
- UniProtKB: P55088 (UniProtKB/Swiss-Prot),   Q50H70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295575   ⟸   NM_001308646
- Peptide Label: isoform M23
- UniProtKB: P55088 (UniProtKB/Swiss-Prot),   Q50H70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001304658   ⟸   NM_001317729
- Peptide Label: isoform M1x
- UniProtKB: P55088 (UniProtKB/Swiss-Prot),   Q8BR89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295576   ⟸   NM_001308647
- Peptide Label: isoform M23
- UniProtKB: P55088 (UniProtKB/Swiss-Prot),   Q50H70 (UniProtKB/TrEMBL),   Q8BR89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000078088   ⟸   ENSMUST00000079081
RefSeq Acc Id: ENSMUSP00000159185   ⟸   ENSMUST00000238946
RefSeq Acc Id: ENSMUSP00000157000   ⟸   ENSMUST00000235044
RefSeq Acc Id: ENSMUSP00000157347   ⟸   ENSMUST00000234391
RefSeq Acc Id: ENSMUSP00000157152   ⟸   ENSMUST00000234473
RefSeq Acc Id: ENSMUSP00000157324   ⟸   ENSMUST00000234466
RefSeq Acc Id: ENSMUSP00000157060   ⟸   ENSMUST00000234643
RefSeq Acc Id: ENSMUSP00000157261   ⟸   ENSMUST00000234533
RefSeq Acc Id: ENSMUSP00000157239   ⟸   ENSMUST00000234518
RefSeq Acc Id: ENSMUSP00000157337   ⟸   ENSMUST00000234053

Promoters
RGD ID:13677168
Promoter ID:EPDNEW_M22733
Type:initiation region
Name:Aqp4_1
Description:Mus musculus aquaporin 4 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22734  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381815,403,649 - 15,403,709EPDNEW
RGD ID:13677170
Promoter ID:EPDNEW_M22734
Type:single initiation site
Name:Aqp4_2
Description:Mus musculus aquaporin 4 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22733  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381815,409,412 - 15,409,472EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107387 AgrOrtholog
Ensembl Genes ENSMUSG00000024411 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000078088 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000157000 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000157060 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000157152 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000157239 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000157261 UniProtKB/TrEMBL
  ENSMUSP00000157324 UniProtKB/Swiss-Prot
  ENSMUSP00000157337 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000157347 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000159185 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000079081 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000234053 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000234391 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000234466 UniProtKB/Swiss-Prot
  ENSMUST00000234473 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000234518 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000234533 UniProtKB/TrEMBL
  ENSMUST00000234643 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000235044 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000238946 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.20.1080.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Aquaporin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aquaporin_transptr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11829 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:107387 ENTREZGENE
NCBI Gene 11829 ENTREZGENE
PANTHER PTHR19139 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aqp4 PhenoGen
PRINTS MINTRINSICP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81338 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0Z3 ENTREZGENE, UniProtKB/TrEMBL
  A0A3Q4EI78_MOUSE UniProtKB/TrEMBL
  A0A5F8MQ17_MOUSE UniProtKB/TrEMBL
  AQP4_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q50H70 ENTREZGENE, UniProtKB/TrEMBL
  Q8BR89 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary P97818 UniProtKB/Swiss-Prot
  Q4FJP1 UniProtKB/Swiss-Prot
  Q61131 UniProtKB/Swiss-Prot
  Q61132 UniProtKB/Swiss-Prot
  Q8VHE4 UniProtKB/Swiss-Prot
  Q8VHE5 UniProtKB/Swiss-Prot
  Q9EQI3 UniProtKB/Swiss-Prot