Mir100 (microRNA 100) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: Mir100 (microRNA 100) Rattus norvegicus
Analyze
Symbol: Mir100
Name: microRNA 100
RGD ID: 2325389
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in miRNA-mediated gene silencing by inhibition of translation; miRNA-mediated gene silencing by mRNA destabilization; and negative regulation of vascular associated smooth muscle cell differentiation. Predicted to act upstream of or within several processes, including cellular hyperosmotic salinity response; cellular response to forskolin; and cellular response to leukemia inhibitory factor. Predicted to be located in synapse. Orthologous to human MIR100 (microRNA 100); INTERACTS WITH bleomycin A2; methapyrilene; nitrofen.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-100; Mir125b2; rno-mir-100
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2841,901,225 - 41,901,304 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl841,901,225 - 41,901,304 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx847,393,696 - 47,393,775 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0845,672,341 - 45,672,420 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0843,539,916 - 43,539,995 (+)NCBIRnor_WKY
Rnor_6.0845,746,948 - 45,747,027 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl845,746,948 - 45,747,027 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0844,222,150 - 44,222,229 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera841,500,067 - 41,500,146 (+)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14691248   PMID:16381832   PMID:17028171   PMID:17604727   PMID:20403161   PMID:20439489   PMID:20805985   PMID:21993888   PMID:22249248   PMID:22897173   PMID:23646144   PMID:25406880  
PMID:25736855   PMID:25858512   PMID:26409044   PMID:31696457   PMID:34138410   PMID:35356885   PMID:35587661  


Genomics

Comparative Map Data
Mir100
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2841,901,225 - 41,901,304 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl841,901,225 - 41,901,304 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx847,393,696 - 47,393,775 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0845,672,341 - 45,672,420 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0843,539,916 - 43,539,995 (+)NCBIRnor_WKY
Rnor_6.0845,746,948 - 45,747,027 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl845,746,948 - 45,747,027 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0844,222,150 - 44,222,229 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera841,500,067 - 41,500,146 (+)NCBICelera
Cytogenetic Map8q22NCBI
MIR100
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811122,152,229 - 122,152,308 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl11122,152,229 - 122,152,308 (-)EnsemblGRCh38hg38GRCh38
GRCh3711122,022,937 - 122,023,016 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611121,528,146 - 121,528,225 (-)NCBINCBI36Build 36hg18NCBI36
Celera11119,183,604 - 119,183,683 (-)NCBICelera
Cytogenetic Map11q24.1NCBI
HuRef11117,969,463 - 117,969,542 (-)NCBIHuRef
CHM1_111121,910,234 - 121,910,313 (-)NCBICHM1_1
T2T-CHM13v2.011122,181,220 - 122,181,299 (-)NCBIT2T-CHM13v2.0
Mir100
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39941,442,721 - 41,442,800 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl941,442,721 - 41,442,800 (+)EnsemblGRCm39 Ensembl
GRCm38941,531,425 - 41,531,504 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl941,531,425 - 41,531,504 (+)EnsemblGRCm38mm10GRCm38
MGSCv37941,339,508 - 41,339,587 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera938,770,225 - 38,770,304 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
MIR99A-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1512,047,369 - 12,047,425 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl512,047,369 - 12,047,425 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha512,102,421 - 12,102,477 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0511,996,862 - 11,996,918 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl511,996,862 - 11,996,918 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1512,100,869 - 12,100,925 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0512,040,078 - 12,040,134 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0512,078,962 - 12,079,018 (+)NCBIUU_Cfam_GSD_1.0
MIR100
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl949,157,909 - 49,157,988 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1949,157,909 - 49,157,988 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2954,383,382 - 54,383,461 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Aqp4rno-miR-100-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Targets
Summary Value
Count of predictions:4679
Count of gene targets:3328
Count of transcripts:3555
Interacting mature miRNAs:rno-miR-100-3p, rno-miR-100-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82664491246711092Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82720571554998217Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)82824291253961020Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82950266550095447Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815442692818Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815458482492Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84186687675097878Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84186701070386132Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 5
Low 1 19 14 12 7 10 58 26 31 10 7
Below cutoff 4 4 4 3 4 2 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_031858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000053625
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl841,901,225 - 41,901,304 (+)Ensembl
Rnor_6.0 Ensembl845,746,948 - 45,747,027 (+)Ensembl
RefSeq Acc Id: NR_031858
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2841,901,225 - 41,901,304 (+)NCBI
Rnor_6.0845,746,948 - 45,747,027 (+)NCBI
Rnor_5.0844,222,150 - 44,222,229 (+)NCBI
Celera841,500,067 - 41,500,146 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325389 AgrOrtholog
BioCyc Gene G2FUF-30804 BioCyc
Ensembl Genes ENSRNOG00000035502 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053625 ENTREZGENE
miRBase MI0000885 ENTREZGENE
NCBI Gene 100314234 ENTREZGENE
PhenoGen Mir100 PhenoGen
RNAcentral URS000040D674 RNACentral
  URS000075B085 RNACentral
  URS000075C55A RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-24 Mir100  microRNA 100  Mir125b2  microRNA 125b-2  Name and Symbol changed 629549 APPROVED
2014-07-29 Mir125b2  microRNA 125b-2  Mir100  microRNA 100  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-14 Mir100  microRNA 100  Mir100  microRNA mir-100  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-06-02 Mir100  microRNA mir-100      Symbol and Name status set to provisional 70820 PROVISIONAL