(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PINK1 mRNA] CTD PMID:31150632 1,1-dichloroethene decreases expression ISO RGD:1314002 6480464 vinylidene chloride results in decreased expression of PINK1 mRNA CTD PMID:26682919 1,4-benzoquinone multiple interactions ISO RGD:1314001 6480464 Acetylcysteine inhibits the reaction [quinone results in increased expression of PINK1 protein] more ... CTD PMID:29567065 1,4-benzoquinone increases expression ISO RGD:1314001 6480464 quinone results in increased expression of PINK1 mRNA, quinone results in increased expression of PINK1 protein CTD PMID:29567065 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine affects response to substance ISO RGD:1314002 6480464 PINK1 protein affects the susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:22511790 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:1314002 6480464 AM 1241 inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:22511790 , PMID:28978077 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO RGD:1314002 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:28978077 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of PINK1 mRNA CTD PMID:30723492 17alpha-ethynylestradiol affects expression ISO RGD:1314002 6480464 Ethinyl Estradiol affects the expression of PINK1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:1314002 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of PINK1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression ISO RGD:1314002 6480464 Ethinyl Estradiol results in decreased expression of PINK1 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:1314001 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of PINK1 mRNA CTD PMID:30165855 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1314002 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of PINK1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PINK1 mRNA CTD PMID:32109520 , PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1314001 6480464 Tetrachlorodibenzodioxin results in increased expression of PINK1 mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PINK1 mRNA CTD PMID:21215274 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of PINK1 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of PINK1 mRNA CTD PMID:21346803 2-hydroxypropanoic acid decreases expression ISO RGD:1314001 6480464 Lactic Acid results in decreased expression of PINK1 mRNA CTD PMID:30851411 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of PINK1 mRNA CTD PMID:30071829 4-nitrophenol increases expression ISO RGD:1314002 6480464 4-nitrophenol results in increased expression of PINK1 mRNA CTD PMID:34673133 5-aza-2'-deoxycytidine affects expression ISO RGD:1314001 6480464 Decitabine affects the expression of PINK1 mRNA CTD PMID:23300844 acetaldehyde decreases expression ISO RGD:1314001 6480464 Acetaldehyde results in decreased expression of PINK1 mRNA, Acetaldehyde results in decreased expression of PINK1 protein CTD PMID:35595033 acetaldehyde multiple interactions ISO RGD:1314001 6480464 PINK1 protein inhibits the reaction [Acetaldehyde results in decreased expression of FTH1 protein] more ... CTD PMID:35595033 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of PINK1 mRNA CTD PMID:31881176 acetylcholine multiple interactions ISO RGD:1314002 6480464 Acetylcholine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PINK1 protein] CTD PMID:34547296 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of PINK1 mRNA CTD PMID:28959563 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of PINK1 mRNA CTD PMID:33354967 aflatoxin B1 multiple interactions ISO RGD:1314002 6480464 PRKN protein affects the reaction [Aflatoxin B1 results in increased expression of PINK1 mRNA], PRKN protein affects the reaction [Aflatoxin B1 results in increased expression of PINK1 protein] CTD PMID:35304092 aflatoxin B1 increases expression ISO RGD:1314002 6480464 Aflatoxin B1 results in increased expression of PINK1 mRNA, Aflatoxin B1 results in increased expression of PINK1 protein CTD PMID:35304092 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of PINK1 protein CTD PMID:35243728 aldehydo-D-glucose multiple interactions ISO RGD:1314001 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA, Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA] CTD PMID:33962019 aldehydo-D-glucose increases expression ISO RGD:1314001 6480464 Glucose results in increased expression of PINK1 mRNA CTD PMID:33962019 aldehydo-D-glucose multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PINK1 protein] CTD PMID:35243728 aluminium atom multiple interactions ISO RGD:1314002 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PINK1 mRNA more ... CTD PMID:34547296 aluminium(0) multiple interactions ISO RGD:1314002 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PINK1 mRNA more ... CTD PMID:34547296 antimycin A multiple interactions ISO RGD:1314001 6480464 [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA more ... CTD PMID:28366621 antimycin A decreases expression ISO RGD:1314001 6480464 Antimycin A results in decreased expression of PINK1 mRNA CTD PMID:33512557 aristolochic acid A increases expression ISO RGD:1314001 6480464 aristolochic acid I results in increased expression of PINK1 mRNA CTD PMID:33212167 aristolochic acids increases expression EXP 6480464 Aristolochic Acids results in increased expression of PINK1 mRNA CTD PMID:19717638 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PINK1 protein CTD PMID:30551535 arsenous acid multiple interactions ISO RGD:1314001 6480464 3-(2 more ... CTD PMID:27318970 arsenous acid increases expression ISO RGD:1314001 6480464 Arsenic Trioxide results in increased expression of PINK1 protein CTD PMID:27318970 arsenous acid multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PINK1 protein] CTD PMID:30551535 atrazine increases expression EXP 6480464 Atrazine results in increased expression of PINK1 mRNA, Atrazine results in increased expression of PINK1 protein CTD PMID:30084861 azoxystrobin decreases expression ISO RGD:1314001 6480464 azoxystrobin results in decreased expression of PINK1 mRNA CTD PMID:33512557 benzo[a]pyrene decreases expression ISO RGD:1314002 6480464 Benzo(a)pyrene results in decreased expression of PINK1 mRNA CTD PMID:20127859 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of PINK1 protein CTD PMID:32619457 benzo[a]pyrene multiple interactions EXP 6480464 [Resveratrol co-treated with Benzo(a)pyrene] results in increased expression of PINK1 protein CTD PMID:32619457 benzo[a]pyrene decreases methylation ISO RGD:1314001 6480464 Benzo(a)pyrene results in decreased methylation of PINK1 promoter CTD PMID:27901495 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1314001 6480464 Diethylhexyl Phthalate analog results in increased expression of PINK1 mRNA more ... CTD PMID:34822940 bisphenol A increases expression ISO RGD:1314002 6480464 bisphenol A results in increased expression of PINK1 mRNA CTD PMID:26063408 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PINK1 mRNA CTD PMID:25181051 more ... bupivacaine multiple interactions ISO RGD:1314002 6480464 HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PINK1 protein] CTD PMID:34793778 bupivacaine decreases expression ISO RGD:1314002 6480464 Bupivacaine results in decreased expression of PINK1 protein CTD PMID:34793778 buspirone increases expression EXP 6480464 Buspirone results in increased expression of PINK1 mRNA CTD PMID:24136188 cadmium atom multiple interactions ISO RGD:1314002 6480464 3-(2 more ... CTD PMID:25464205 , PMID:34952138 cadmium atom increases expression ISO RGD:1314002 6480464 Cadmium results in increased expression of PINK1 CTD PMID:25464205 cadmium dichloride increases expression ISO RGD:1314002 6480464 Cadmium Chloride results in increased expression of PINK1 mRNA CTD PMID:20883709 cadmium dichloride multiple interactions ISO RGD:1314002 6480464 3-(2 more ... CTD PMID:34952138 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of PINK1 mRNA CTD PMID:33453195 calcitriol increases expression ISO RGD:1314001 6480464 Calcitriol results in increased expression of PINK1 mRNA CTD PMID:16002434 carbon nanotube decreases expression ISO RGD:1314002 6480464 Nanotubes more ... CTD PMID:25554681 carbonyl cyanide p-trifluoromethoxyphenylhydrazone multiple interactions ISO RGD:1314002 6480464 PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 carnosic acid multiple interactions ISO RGD:1314001 6480464 PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein]] more ... CTD PMID:30707903 CCCP multiple interactions ISO RGD:1314001 6480464 [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein more ... CTD PMID:28673964 more ... CCCP increases expression ISO RGD:1314001 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of PINK1 protein CTD PMID:27318970 , PMID:29371327 CCCP increases stability ISO RGD:1314001 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased stability of PINK1 protein CTD PMID:26070385 CCCP multiple interactions ISO RGD:1314002 6480464 PINK1 gene mutant form inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] CTD PMID:22872702 CCCP multiple interactions EXP 6480464 BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein], PINK1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] CTD PMID:24879156 CCCP affects localization EXP 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein CTD PMID:24879156 chloroquine multiple interactions ISO RGD:1314002 6480464 Chloroquine inhibits the reaction [Acetaminophen results in increased expression of PINK1 protein], Chloroquine inhibits the reaction [coenzyme Q10 promotes the reaction [Acetaminophen results in increased expression of PINK1 protein]] CTD PMID:33271250 chlorpyrifos increases stability ISO RGD:1314001 6480464 Chlorpyrifos results in increased stability of PINK1 protein CTD PMID:26070385 chlorpyrifos decreases expression ISO RGD:1314002 6480464 Chlorpyrifos results in decreased expression of PINK1 mRNA CTD PMID:29156651 chromium(6+) multiple interactions ISO RGD:1314001 6480464 HMGA2 protein promotes the reaction [chromium hexavalent ion results in increased expression of PINK1 protein] CTD PMID:32866567 chromium(6+) increases expression ISO RGD:1314001 6480464 chromium hexavalent ion results in increased expression of PINK1 protein CTD PMID:30715550 , PMID:32866567 chromium(6+) increases expression ISO RGD:1314002 6480464 chromium hexavalent ion results in increased expression of PINK1 protein CTD PMID:32866567 cisplatin multiple interactions ISO RGD:1314001 6480464 [Piroxicam co-treated with Cisplatin] results in increased expression of PINK1 mRNA CTD PMID:21858171 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of PINK1 protein CTD PMID:28698153 cisplatin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Cisplatin results in increased expression of PINK1 protein] CTD PMID:28698153 cisplatin affects expression ISO RGD:1314001 6480464 Cisplatin affects the expression of PINK1 mRNA CTD PMID:23300844 clofibric acid affects expression EXP 6480464 Clofibric Acid affects the expression of PINK1 mRNA CTD PMID:17602206 coenzyme Q10 multiple interactions ISO RGD:1314002 6480464 Chloroquine inhibits the reaction [coenzyme Q10 promotes the reaction [Acetaminophen results in increased expression of PINK1 protein]], coenzyme Q10 promotes the reaction [Acetaminophen results in increased expression of PINK1 protein] CTD PMID:33271250 colforsin daropate hydrochloride multiple interactions ISO RGD:1314001 6480464 PINK1 protein affects the reaction [Colforsin results in decreased expression of DNM1L protein] CTD PMID:24792327 copper atom decreases expression EXP 6480464 Copper results in decreased expression of PINK1 mRNA CTD PMID:22465980 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of PINK1 mRNA CTD PMID:22465980 coumestrol decreases expression ISO RGD:1314001 6480464 Coumestrol results in decreased expression of PINK1 mRNA CTD PMID:19167446 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Cisplatin results in increased expression of PINK1 protein] CTD PMID:28698153 cyclosporin A multiple interactions ISO RGD:1314002 6480464 Cyclosporine inhibits the reaction [Cadmium results in increased expression of PINK1] CTD PMID:25464205 cyclosporin A multiple interactions ISO RGD:1314001 6480464 Cyclosporine inhibits the reaction [arsenic trioxide results in increased expression of PINK1 protein] more ... CTD PMID:27318970 , PMID:29567065 cyclosporin A decreases expression ISO RGD:1314001 6480464 Cyclosporine results in decreased expression of PINK1 protein CTD PMID:27318970 D-glucose multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PINK1 protein] CTD PMID:35243728 D-glucose increases expression ISO RGD:1314001 6480464 Glucose results in increased expression of PINK1 mRNA CTD PMID:33962019 D-glucose multiple interactions ISO RGD:1314001 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA, Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA] CTD PMID:33962019 D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of PINK1 protein CTD PMID:35243728 decabromodiphenyl ether decreases expression ISO RGD:1314002 6480464 decabromobiphenyl ether results in decreased expression of PINK1 mRNA CTD PMID:29699156 deguelin decreases expression ISO RGD:1314001 6480464 deguelin results in decreased expression of PINK1 mRNA CTD PMID:33512557 desferrioxamine B multiple interactions ISO RGD:1314001 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA, Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA] CTD PMID:33962019 diarsenic trioxide increases expression ISO RGD:1314001 6480464 Arsenic Trioxide results in increased expression of PINK1 protein CTD PMID:27318970 diarsenic trioxide multiple interactions ISO RGD:1314001 6480464 3-(2 more ... CTD PMID:27318970 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PINK1 protein CTD PMID:30551535 diarsenic trioxide multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PINK1 protein] CTD PMID:30551535 diazinon decreases expression EXP 6480464 Diazinon results in decreased expression of PINK1 mRNA CTD PMID:21968025 dioxygen multiple interactions ISO RGD:1314002 6480464 [Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of PINK1 protein, genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of PINK1 protein] CTD PMID:28477916 dioxygen multiple interactions EXP 6480464 [Antagomirs results in decreased expression of MIR205 mRNA] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of PINK1 protein] more ... CTD PMID:21159781 more ... dithionite(2-) multiple interactions EXP 6480464 [Oxygen co-treated with Dithionite] results in decreased expression of PINK1 protein, Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in decreased expression of PINK1 protein] CTD PMID:34078833 dopamine multiple interactions ISO RGD:1314002 6480464 [PINK1 mutant form results in increased susceptibility to Paraquat] which results in decreased abundance of Dopamine, Paraquat affects the reaction [PINK1 protein affects the abundance of Dopamine] CTD PMID:22043175 dopamine affects abundance ISO RGD:1314002 6480464 PINK1 protein affects the abundance of Dopamine CTD PMID:22043175 dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [sappanone A inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of PINK1 protein]] CTD PMID:34358556 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of PINK1 protein CTD PMID:26678157 , PMID:29966675 doxorubicin multiple interactions ISO RGD:1314001 6480464 3-(2 more ... CTD PMID:29729358 doxorubicin increases expression ISO RGD:1314001 6480464 Doxorubicin results in increased expression of PINK1 protein CTD PMID:29729358 doxorubicin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Doxorubicin results in increased expression of PINK1 protein] CTD PMID:29966675 ethanol decreases expression ISO RGD:1314001 6480464 Ethanol results in decreased expression of PINK1 mRNA, Ethanol results in decreased expression of PINK1 protein CTD PMID:35595033 ethanol multiple interactions ISO RGD:1314001 6480464 PINK1 protein inhibits the reaction [Ethanol results in decreased expression of FTH1 protein] more ... CTD PMID:35595033 fenpyroximate decreases expression ISO RGD:1314001 6480464 fenpyroximate results in decreased expression of PINK1 mRNA CTD PMID:33512557 fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of PINK1 mRNA CTD PMID:31734597 furosemide multiple interactions EXP 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PINK1 protein CTD PMID:29860548 Fusaric acid increases expression ISO RGD:1314001 6480464 Fusaric Acid results in increased expression of PINK1 protein CTD PMID:30582969 Genipin multiple interactions ISO RGD:1314002 6480464 genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of PINK1 protein] CTD PMID:28477916 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of PINK1 mRNA CTD PMID:24136188 glucose decreases expression EXP 6480464 Glucose results in decreased expression of PINK1 protein CTD PMID:35243728 glucose increases expression ISO RGD:1314001 6480464 Glucose results in increased expression of PINK1 mRNA CTD PMID:33962019 glucose multiple interactions ISO RGD:1314001 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA, Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA] CTD PMID:33962019 glucose multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PINK1 protein] CTD PMID:35243728 hexadecanoic acid multiple interactions ISO RGD:1314001 6480464 3-N-1(spermine)-7 more ... CTD PMID:32369900 Honokiol multiple interactions EXP 6480464 honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of PINK1 protein], SIRT3 protein affects the reaction [honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of PINK1 protein]] CTD PMID:34752757 hydrogen peroxide multiple interactions ISO RGD:1314001 6480464 BMAL1 protein affects the reaction [Polyphenols inhibits the reaction [Hydrogen Peroxide results in decreased expression of PINK1 mRNA]] more ... CTD PMID:21366594 , PMID:30316844 hydrogen peroxide decreases expression ISO RGD:1314001 6480464 Hydrogen Peroxide results in decreased expression of PINK1 mRNA CTD PMID:30316844 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of PINK1 protein CTD PMID:21159781 hydrogen peroxide multiple interactions ISO RGD:1314002 6480464 PINK1 protein affects the reaction [Hydrogen Peroxide results in increased chemical synthesis of Reactive Oxygen Species] CTD PMID:21421046 hydrogen peroxide affects response to substance ISO RGD:1314001 6480464 PINK1 protein affects the susceptibility to Hydrogen Peroxide CTD PMID:21366594 inositol multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PINK1 protein] CTD PMID:35243728 iodixanol multiple interactions EXP 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PINK1 protein CTD PMID:29860548 lead diacetate multiple interactions ISO RGD:1314001 6480464 lead acetate promotes the reaction [PINK1 protein binds to ATM protein], lead acetate results in increased expression of and results in increased phosphorylation of PINK1 protein CTD PMID:29660402 lead(0) affects expression ISO RGD:1314001 6480464 Lead affects the expression of PINK1 mRNA CTD PMID:28903495 lead(2+) affects expression ISO RGD:1314001 6480464 Lead affects the expression of PINK1 mRNA CTD PMID:28903495 manganese(II) chloride decreases expression ISO RGD:1314001 6480464 manganese chloride results in decreased expression of PINK1 mRNA CTD PMID:27913844 manganese(II) chloride increases methylation ISO RGD:1314001 6480464 manganese chloride results in increased methylation of PINK1 gene CTD PMID:27913844 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PINK1 protein], Melatonin inhibits the reaction [Doxorubicin results in increased expression of PINK1 protein] CTD PMID:26882442 , PMID:29966675 melatonin multiple interactions ISO RGD:1314001 6480464 Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA] CTD PMID:33962019 methylmercury chloride decreases expression ISO RGD:1314001 6480464 methylmercuric chloride results in decreased expression of PINK1 mRNA CTD PMID:28001369 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide decreases expression EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of PINK1 protein CTD PMID:29870751 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of PINK1 protein] CTD PMID:29870751 N-acetyl-L-cysteine multiple interactions ISO RGD:1314002 6480464 Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PINK1 mRNA], Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PINK1] CTD PMID:25464205 , PMID:34547296 N-acetyl-L-cysteine multiple interactions ISO RGD:1314001 6480464 Acetylcysteine inhibits the reaction [quinone results in increased expression of PINK1 protein] CTD PMID:29567065 N-acetylsphingosine decreases response to substance ISO RGD:1314001 6480464 PINK1 protein results in decreased susceptibility to N-acetylsphingosine CTD PMID:24792327 N-acetylsphingosine decreases response to substance ISO RGD:1314002 6480464 PINK1 protein results in decreased susceptibility to N-acetylsphingosine CTD PMID:24792327 N-ethyl-N-nitrosourea increases mutagenesis EXP 6480464 Ethylnitrosourea results in increased mutagenesis of PINK1 gene CTD PMID:16495775 N-methyl-4-phenylpyridinium affects response to substance ISO RGD:1314001 6480464 PINK1 protein affects the susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:16226715 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PINK1 protein CTD PMID:24475098 N-methyl-4-phenylpyridinium increases response to substance ISO RGD:1314001 6480464 PINK1 gene mutant form results in increased susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:20547144 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:1314001 6480464 PINK1 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA], PINK1 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein] CTD PMID:21366594 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of PINK1 mRNA CTD PMID:24136188 O-acetyl-L-carnitine multiple interactions ISO RGD:1314002 6480464 Acetylcarnitine inhibits the reaction [Cadmium results in increased expression of PINK1] CTD PMID:25464205 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of PINK1 mRNA CTD PMID:19717638 oleanolic acid increases expression ISO RGD:1314001 6480464 Oleanolic Acid results in increased expression of PINK1 protein CTD PMID:35690101 oleic acid multiple interactions ISO RGD:1314001 6480464 3-N-1(spermine)-7 more ... CTD PMID:32369900 oligomycin A multiple interactions ISO RGD:1314001 6480464 [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA more ... CTD PMID:28366621 oxidopamine decreases expression ISO RGD:1314001 6480464 Oxidopamine results in decreased expression of PINK1 protein CTD PMID:30707903 oxidopamine multiple interactions ISO RGD:1314001 6480464 PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein]] more ... CTD PMID:30707903 ozone multiple interactions ISO RGD:1314002 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of PINK1 mRNA CTD PMID:34911549 ozone increases expression ISO RGD:1314002 6480464 Ozone results in increased expression of PINK1 protein CTD PMID:35866636 paracetamol affects expression ISO RGD:1314002 6480464 Acetaminophen affects the expression of PINK1 mRNA CTD PMID:17562736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of PINK1 mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:1314001 6480464 Acetaminophen results in increased expression of PINK1 mRNA CTD PMID:22230336 , PMID:25704631 paracetamol multiple interactions ISO RGD:1314002 6480464 Chloroquine inhibits the reaction [Acetaminophen results in increased expression of PINK1 protein] more ... CTD PMID:33271250 paracetamol increases expression ISO RGD:1314002 6480464 Acetaminophen results in increased expression of PINK1 protein CTD PMID:33271250 paraquat decreases expression ISO RGD:1314002 6480464 Paraquat results in decreased expression of PINK1 mRNA CTD PMID:22563483 paraquat affects response to substance ISO RGD:1314001 6480464 PINK1 protein affects the susceptibility to Paraquat CTD PMID:33383311 paraquat multiple interactions ISO RGD:1314001 6480464 oren gedoku to inhibits the reaction [Paraquat results in increased expression of and affects the localization of PINK1 protein] more ... CTD PMID:30144575 , PMID:33383311 paraquat increases expression ISO RGD:1314001 6480464 Paraquat results in increased expression of PINK1 protein CTD PMID:30144575 paraquat multiple interactions ISO RGD:1314002 6480464 [PINK1 mutant form results in increased susceptibility to Paraquat] which results in decreased abundance of Dopamine, Paraquat affects the reaction [PINK1 protein affects the abundance of Dopamine] CTD PMID:22043175 paraquat increases response to substance ISO RGD:1314002 6480464 PINK1 mutant form results in increased susceptibility to Paraquat CTD PMID:22043175 phlorizin increases expression ISO RGD:1314002 6480464 Phlorhizin results in increased expression of PINK1 mRNA CTD PMID:22538082 picoxystrobin decreases expression ISO RGD:1314001 6480464 picoxystrobin results in decreased expression of PINK1 mRNA CTD PMID:33512557 pirinixic acid multiple interactions ISO RGD:1314002 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PINK1 mRNA CTD PMID:19710929 piroxicam multiple interactions ISO RGD:1314001 6480464 [Piroxicam co-treated with Cisplatin] results in increased expression of PINK1 mRNA CTD PMID:21858171 poly(vinylpyrrolidone) multiple interactions ISO RGD:1314002 6480464 [Silver Compounds co-treated with Povidone] results in increased expression of PINK1 protein CTD PMID:35697184 pyrimidifen decreases expression ISO RGD:1314001 6480464 pyrimidifen results in decreased expression of PINK1 mRNA CTD PMID:33512557 rac-lactic acid decreases expression ISO RGD:1314001 6480464 Lactic Acid results in decreased expression of PINK1 mRNA CTD PMID:30851411 reactive oxygen species increases chemical synthesis ISO RGD:1314001 6480464 PINK1 gene mutant form results in increased chemical synthesis of Reactive Oxygen Species CTD PMID:20547144 reactive oxygen species decreases chemical synthesis ISO RGD:1314002 6480464 PINK1 protein results in decreased chemical synthesis of Reactive Oxygen Species CTD PMID:21421046 reactive oxygen species multiple interactions ISO RGD:1314002 6480464 PINK1 protein affects the reaction [Hydrogen Peroxide results in increased chemical synthesis of Reactive Oxygen Species] CTD PMID:21421046 remifentanil multiple interactions EXP 6480464 [Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of PINK1 protein]] more ... CTD PMID:34078833 resveratrol increases expression ISO RGD:1314002 6480464 resveratrol results in increased expression of PINK1 mRNA CTD PMID:22610192 resveratrol increases expression EXP 6480464 Resveratrol results in increased expression of PINK1 protein CTD PMID:32619457 resveratrol multiple interactions ISO RGD:1314001 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of PINK1 mRNA CTD PMID:23557933 resveratrol multiple interactions EXP 6480464 [Resveratrol co-treated with Benzo(a)pyrene] results in increased expression of PINK1 protein CTD PMID:32619457 rotenone decreases response to substance ISO RGD:1314001 6480464 PINK1 protein results in decreased susceptibility to Rotenone CTD PMID:19492085 rotenone multiple interactions ISO RGD:1314002 6480464 [Particulate Matter co-treated with Rotenone] results in decreased expression of PINK1 protein, Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of PINK1 protein] CTD PMID:33823232 rotenone multiple interactions EXP 6480464 [Particulate Matter co-treated with Rotenone] results in decreased expression of PINK1 protein, Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of PINK1 protein] CTD PMID:33823232 rotenone affects localization ISO RGD:1314001 6480464 Rotenone affects the localization of PINK1 protein CTD PMID:32001317 rotenone multiple interactions ISO RGD:1314001 6480464 DNM1L protein affects the reaction [Rotenone affects the localization of PINK1 protein] more ... CTD PMID:32001317 rotenone decreases expression ISO RGD:1314001 6480464 Rotenone results in decreased expression of PINK1 mRNA CTD PMID:33512557 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of PINK1 mRNA, Rotenone results in decreased expression of PINK1 protein CTD PMID:32392329 rotenone increases expression EXP 6480464 Rotenone results in increased expression of PINK1 mRNA CTD PMID:28374803 rotenone affects response to substance ISO RGD:1314002 6480464 PINK1 protein affects the susceptibility to Rotenone CTD PMID:21421046 , PMID:26916954 rotenone affects response to substance ISO RGD:1314001 6480464 PINK1 protein affects the susceptibility to Rotenone CTD PMID:16226715 , PMID:20940149 rotenone increases expression ISO RGD:1314002 6480464 Rotenone results in increased expression of PINK1 protein CTD PMID:20464527 silibinin multiple interactions ISO RGD:1314001 6480464 Silybin inhibits the reaction [Acetaldehyde results in decreased expression of PINK1 mRNA] more ... CTD PMID:35595033 silicon dioxide decreases expression ISO RGD:1314001 6480464 Silicon Dioxide analog results in decreased expression of PINK1 mRNA CTD PMID:25895662 silver(1+) nitrate increases expression ISO RGD:1314002 6480464 Silver Nitrate results in increased expression of PINK1 protein CTD PMID:35697184 sirolimus multiple interactions ISO RGD:1314002 6480464 Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of PINK1 protein], Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of PINK1 protein] CTD PMID:33823232 , PMID:35405287 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of PINK1 protein] CTD PMID:33823232 sodium arsenite increases expression ISO RGD:1314002 6480464 sodium arsenite results in increased expression of PINK1 mRNA CTD PMID:20883709 sodium arsenite multiple interactions EXP 6480464 Rosiglitazone inhibits the reaction [sodium arsenite results in decreased expression of PINK1 protein], Taurine inhibits the reaction [sodium arsenite results in decreased expression of PINK1 protein] CTD PMID:30551535 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of PINK1 protein CTD PMID:30551535 sodium arsenite affects methylation ISO RGD:1314001 6480464 sodium arsenite affects the methylation of PINK1 gene CTD PMID:28589171 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of PINK1 mRNA CTD PMID:25993096 sorafenib multiple interactions ISO RGD:1314001 6480464 [sorafenib co-treated with PRKN protein] results in increased expression of PINK1 protein, PINK1 protein affects the reaction [sorafenib affects the localization of PRKN protein] CTD PMID:28673964 sorafenib increases expression ISO RGD:1314002 6480464 sorafenib results in increased expression of PINK1 protein CTD PMID:28673964 sorafenib increases expression ISO RGD:1314001 6480464 sorafenib results in increased expression of PINK1 protein CTD PMID:28673964 sorafenib affects response to substance ISO RGD:1314002 6480464 PINK1 protein affects the susceptibility to sorafenib CTD PMID:28673964 streptozocin multiple interactions ISO RGD:1314002 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of PINK1 mRNA CTD PMID:33812996 succimer multiple interactions ISO RGD:1314001 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of PINK1 mRNA CTD PMID:26378955 sulforaphane increases expression ISO RGD:1314001 6480464 sulforaphane results in increased expression of PINK1 mRNA CTD PMID:26833863 sulforaphane decreases expression ISO RGD:1314001 6480464 sulforaphane results in decreased expression of PINK1 mRNA CTD PMID:31838189 superoxide affects abundance ISO RGD:1314002 6480464 PINK1 protein affects the abundance of Superoxides CTD PMID:21421046 T-2 toxin multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of PINK1 protein], NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein] CTD PMID:29870751 T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of PINK1 mRNA, T-2 Toxin results in increased expression of PINK1 protein CTD PMID:29870751 tacrolimus hydrate multiple interactions ISO RGD:1314001 6480464 PINK1 protein affects the reaction [Tacrolimus results in increased phosphorylation of DNM1L protein] CTD PMID:19492085 tamoxifen affects expression ISO RGD:1314002 6480464 Tamoxifen affects the expression of PINK1 mRNA CTD PMID:17555576 taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PINK1 protein], Taurine inhibits the reaction [sodium arsenite results in decreased expression of PINK1 protein] CTD PMID:30551535 tebufenpyrad decreases expression ISO RGD:1314001 6480464 4-chloro-N-((4-(1, 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of PINK1 mRNA CTD PMID:33512557 temozolomide decreases expression ISO RGD:1314001 6480464 Temozolomide results in decreased expression of PINK1 mRNA CTD PMID:31758290 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of PINK1 mRNA, Carbon Tetrachloride results in decreased expression of PINK1 protein CTD PMID:26882442 , PMID:31150632 tetrachloromethane multiple interactions ISO RGD:1314002 6480464 Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of PINK1 protein] CTD PMID:35405287 tetrachloromethane increases expression ISO RGD:1314002 6480464 Carbon Tetrachloride results in increased expression of PINK1 protein CTD PMID:35405287 tetrachloromethane multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PINK1 protein], schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PINK1 mRNA] CTD PMID:26882442 , PMID:31150632 thapsigargin increases expression ISO RGD:1314001 6480464 Thapsigargin results in increased expression of PINK1 mRNA CTD PMID:22378314 thifluzamide decreases expression ISO RGD:1314001 6480464 thifluzamide results in decreased expression of PINK1 mRNA CTD PMID:33512557 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of PINK1 mRNA CTD PMID:34492290 titanium dioxide decreases expression ISO RGD:1314002 6480464 titanium dioxide results in decreased expression of PINK1 mRNA CTD PMID:23557971 titanium dioxide increases expression ISO RGD:1314001 6480464 titanium dioxide results in increased expression of PINK1 mRNA CTD PMID:30273564 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of PINK1 mRNA CTD PMID:33387578 trichostatin A affects expression ISO RGD:1314001 6480464 trichostatin A affects the expression of PINK1 mRNA CTD PMID:28542535 trifloxystrobin increases expression ISO RGD:1314001 6480464 trifloxystrobin results in increased expression of PINK1 protein CTD PMID:27853101 trifloxystrobin multiple interactions ISO RGD:1314001 6480464 MitoTEMPO inhibits the reaction [trifloxystrobin results in increased expression of PINK1 protein] CTD PMID:27853101 trifluoperazine multiple interactions ISO RGD:1314001 6480464 [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA more ... CTD PMID:28366621 trovafloxacin increases expression EXP 6480464 trovafloxacin results in increased expression of PINK1 mRNA CTD PMID:24136188 tunicamycin decreases expression ISO RGD:1314002 6480464 Tunicamycin results in decreased expression of PINK1 mRNA CTD PMID:17127020 tunicamycin increases expression ISO RGD:1314001 6480464 Tunicamycin results in increased expression of PINK1 mRNA CTD PMID:22378314 urethane increases expression ISO RGD:1314001 6480464 Urethane results in increased expression of PINK1 mRNA CTD PMID:28818685 valproic acid affects expression ISO RGD:1314002 6480464 Valproic Acid affects the expression of PINK1 mRNA CTD PMID:17292431 valproic acid increases expression ISO RGD:1314001 6480464 Valproic Acid results in increased expression of PINK1 mRNA CTD PMID:23179753 more ... vancomycin increases expression ISO RGD:1314002 6480464 Vancomycin results in increased expression of PINK1 mRNA CTD PMID:18930951 vitamin E increases expression ISO RGD:1314001 6480464 Vitamin E results in increased expression of PINK1 mRNA CTD PMID:19244175
