Niddm30 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Niddm30 (Non-insulin dependent diabetes mellitus QTL 30) Rattus norvegicus

Symbol: Niddm30
Name: Non-insulin dependent diabetes mellitus QTL 30
RGD ID: 70156
Previously known as: Nidd12/of
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: blood glucose level area under curve (AUC)   (CMO:0000350)    
LOD Score: 3.98
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85134,369,218 - 156,289,444RGD_MAPPER_PIPELINE
mRatBN7.25129,132,447 - 151,006,154RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05134,502,140 - 157,212,422RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05138,292,963 - 160,953,783RGDRnor5.0
RGSC_v3.45135,910,738 - 157,584,492RGDRGSC3.4
RGSC_v3.15135,915,964 - 157,594,531RGD
Cross Type: F2
Strains Crossed: F344/DuCrlCrlj OLETF/Got 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm30Ratimpaired glucose tolerance  QTM 69696 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm30Ratblood glucose level area under curve (AUC)  IDA 69696 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm30Ratfasting  IDA 69696 RGD 
Niddm30Ratglucose solution, 2.8M  IDA 69696 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm30Ratoral glucose tolerance test  IDA 69696 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm30RatF344/DuCrlCrlj  IEA 69696 RGD 
Niddm30RatOLETF/Got  IEA 69696 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm30Ratblood glucose amount  IDA 69696 RGD 


#
Reference Title
Reference Citation
1. QTL Data Transfer QTL data import from the RatMap database
2. Identification of genetic loci involved in diabetes using a rat model of depression. Solberg Woods LC, etal., Mamm Genome. 2009 Aug 22.
3. Identification of novel non-insulin-dependent diabetes mellitus susceptibility loci in the Otsuka Long-Evans Tokushima fatty rat by MQM-mapping method. Sugiura K, etal., Mamm Genome 1999 Dec;10(12):1126-31.
4. Genetic dissection of complex genetic factor involved in NIDDM of OLETF rat. Yamada T, etal., Exp Diabetes Res. 2012;2012:582546. doi: 10.1155/2012/582546. Epub 2012 Oct 15.

Related QTL Description Reference
Gluco52 maps to same region RGD:2312611



1 to 20 of 595 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
68945Cyp4a1cytochrome P450, family 4, subfamily a, polypeptide 15129123323129137464Rat
2480Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 15129139019129176860Rat
1584916Fdps-ps2farnesyl diphosphate synthase, pseudogene 25129169497129172588Rat
1310351Efcab14EF-hand calcium binding domain 145129218139129258628Rat
1585134Tex38testis expressed 385129260652129265086Rat
1305417Atpaf1ATP synthase mitochondrial F1 complex assembly factor 15129265789129292463Rat
1307821Mob3cMOB kinase activator 3C5129306255129315264Rat
1559603Mknk1MAPK interacting serine/threonine kinase 15129318128129357641Rat
1584061Kncnkinocilin5129363464129366907Rat
41051438Tmem275transmembrane protein 2755129376602129377135Rat
1308265Dmbx1diencephalon/mesencephalon homeobox 15129394221129403040Rat
61808Faahfatty acid amide hydrolase5129479774129499018Rat
1559652Nsun4NOP2/Sun RNA methyltransferase 45129511224129532498Rat
1305987Uqcrhubiquinol-cytochrome c reductase hinge protein5129545978129554173Rat
1311221Lrrc41leucine rich repeat containing 415129554547129575450Rat
1310600Rad54lRAD54 like5129575431129605100Rat
1566001Lurap1leucine rich adaptor protein 15129618926129628651Rat
1359396Pomgnt1protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)5129634274129644150Rat
1303308Tspan1tetraspanin 15129646139129659383Rat
6491750P3r3urfPIK3R3 upstream open reading frame5129656654129673140Rat

1 to 20 of 595 rows
1 to 20 of 819 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10455D5Wox21145147939831147939945Ratregion
10490D5Uwm51715147340163147340334Ratregion
10491D5Wox142255147340196147340421Ratregion
10496D5Mco182005150175116150175316Ratregion
10860D5Wox151195141899404141899523Ratregion
34136D5Mgh212185144377876144378094Ratregion
34168D5Mgh221615151005994151006154Ratregion
34210D5Mgh141505143608201143608494Ratregion
34210D5Mgh141505143608344143608494Ratregion
34220D5Mgh131485133529271133529419Ratregion
34441D5Mgh202225133916727133916949Ratregion
34443D5Mgh81415143069996143070159Ratregion
34581D5Mgh272285129132447129132675Ratregion
34583D5Rjr11745129132428129132602Ratregion
34603D5Mit192055133752562133752767Ratregion
34706D5Mgh181075134972873134972980Ratregion
11303D5Wox111285132743341132743469Ratregion
11304D5Arb72325132744136132744368Ratregion
33680D5Mit132045131345754131345958Ratregion
33731D5Mit141735131378081131378254Ratregion
1 to 20 of 819 rows

Flank 1: (D5Mgh27)
Rat AssemblyChrPosition (strand)Source
GRCr85134,369,218 - 134,369,446 (+)Marker Load Pipeline
mRatBN7.25129,132,447 - 129,132,675 (+)MAPPER
Rnor_6.05134,502,140 - 134,502,367NCBI
Rnor_5.05138,292,963 - 138,293,190UniSTS
RGSC_v3.45135,910,738 - 135,910,966RGD
RGSC_v3.45135,910,739 - 135,910,966UniSTS
RGSC_v3.15135,915,964 - 135,916,192RGD
Celera5127,670,139 - 127,670,366UniSTS
RH 3.4 Map5839.41RGD
RH 3.4 Map5839.41UniSTS
RH 2.0 Map5820.9RGD
Cytogenetic Map5q36UniSTS
Flank 2: (D5Mgh22)
Rat AssemblyChrPosition (strand)Source
GRCr85156,289,283 - 156,289,444 (+)Marker Load Pipeline
mRatBN7.25151,005,994 - 151,006,154 (+)MAPPER
Rnor_6.05157,212,263 - 157,212,422NCBI
Rnor_5.05160,953,624 - 160,953,783UniSTS
RGSC_v3.45157,584,332 - 157,584,492RGD
RGSC_v3.45157,584,333 - 157,584,492UniSTS
RGSC_v3.15157,594,371 - 157,594,531RGD
Celera5149,394,047 - 149,394,206UniSTS
RH 3.4 Map51033.4RGD
RH 3.4 Map51033.4UniSTS
RH 2.0 Map51032.4RGD


1 to 10 of 65 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat

1 to 10 of 65 rows


Database
Acc Id
Source(s)
NCBI Gene Niddm30

Note Type Note Reference