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Gene: Macf1 (microtubule-actin crosslinking factor 1) Rattus norvegicus
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Symbol: Macf1
Name: microtubule-actin crosslinking factor 1
Description: Predicted to have ATPase activity; actin filament binding activity; and microtubule minus-end binding activity. Involved in positive regulation of Wnt signaling pathway. Localizes to the membrane. Predicted to colocalize with the intermediate filament. Human ortholog(s) of this gene implicated in lissencephaly. Orthologous to human MACF1 (microtubule actin crosslinking factor 1); INTERACTS WITH amphetamine; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: actin cross-linking family 7; LOC298511; LOC362587; microtubule-actin cross-linking factor 1; similar to microfilament and actin filament cross-linker protein isoform b
Orthologs:
Homo sapiens (human) : MACF1 (microtubule actin crosslinking factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Macf1 (microtubule-actin crosslinking factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Macf1 (microtubule actin crosslinking factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MACF1 (microtubule actin crosslinking factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Macf1 (microtubule actin crosslinking factor 1)
Sus scrofa (pig) : MACF1 (microtubule actin crosslinking factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05141,039,455 - 141,363,524 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5141,039,468 - 141,363,524 (-)Ensembl
Rnor_5.05144,829,588 - 145,151,477 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,659,726 - 142,986,873 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15142,667,739 - 142,701,960 (-)NCBI
Celera5134,162,059 - 134,482,913 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Macf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306057
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.