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Gene: Ldlrap1 (low density lipoprotein receptor adaptor protein 1) Rattus norvegicus
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Symbol: Ldlrap1
Name: low density lipoprotein receptor adaptor protein 1
RGD ID: 1563417
Description: Predicted to have several functions, including AP-1 adaptor complex binding activity; AP-2 adaptor complex binding activity; and amyloid-beta binding activity. Predicted to be involved in several processes, including cholesterol homeostasis; low-density lipoprotein particle clearance; and receptor-mediated endocytosis. Localizes to axon. Human ortholog(s) of this gene implicated in autosomal recessive hypercholesterolemia. Orthologous to human LDLRAP1 (low density lipoprotein receptor adaptor protein 1); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: autosomal recessive hypercholesterolemia protein homolog; LOC500564; low density lipoprotein receptor adapter protein 1; RGD1563417; similar to LDL receptor adaptor protein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05152,964,294 - 152,987,286 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,966,591 - 152,987,211 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,742,863 - 156,765,855 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,504,535 - 153,527,523 (-)NCBIRGSC3.4rn4RGSC3.4
Celera5145,368,945 - 145,391,939 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ldlrap1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563417
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.