Bp292 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp292 (Blood pressure QTL 292) Rattus norvegicus

Symbol: Bp292
Name: Blood pressure QTL 292
RGD ID: 1598819
Previously known as: BP-f1
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: 4.3
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85133,081,618 - 172,190,305RGD_MAPPER_PIPELINE
mRatBN7.25127,798,274 - 166,875,058RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05133,943,857 - 173,707,219RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05137,693,256 - 177,180,328RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45134,356,746 - 173,096,209RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.15134,366,785 - 173,106,704RGD
Cross Type: intercross
Strains Crossed: SR/JrHsd SS/JrHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp292Rathypertension  IDA 1581737 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp292Ratincreased systemic arterial systolic blood pressure  IDA 1581737 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp292Ratsystolic blood pressure  IDA 1581737 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp292Ratcontrolled sodium content diet  IDA 1581737 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp292Ratintra-aortic abdominal radiotelemetry  IDA 1581737 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp292RatSR/JrHsd  IEA 1581737 RGD 
Bp292RatSS/JrHsd  IEA 1581737 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp292Ratarterial blood pressure trait  IDA 1581737 RGD 


#
Reference Title
Reference Citation
1. Sex-specific QTLs and interacting loci underlie salt-sensitive hypertension and target organ complications in Dahl S/jrHS hypertensive rats. Herrera VL, etal., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23.
2. Dahl (S x R) congenic strain analysis confirms and defines a chromosome 5 female-specific blood pressure quantitative trait locus to <7 Mbp. Herrera VL, etal., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30.

Related QTL Description Reference
Bp359 sub_region RGD:7364997



1 to 20 of 1002 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1587504Skint10selection and upkeep of intraepithelial T cells 105127769022127811541Rat
41385175Traf3ip2-ps1Traf3 interacting protein 2, pseudogene 15127813498127814580Rat
1584918Eef1a1-ps9eukaryotic translation elongation factor 1 alpha 1, pseudogene 95127824597127825986Rat
1586386Trabd2bTraB domain containing 2B5127941198128158946Rat
1304642Foxd2forkhead box D25128427986128430709Rat
11398866LOC108351105uncharacterized LOC1083511055128430904128442177Rat
621727Foxe3forkhead box E35128444912128446494Rat
1310116Cmpk1cytidine/uridine monophosphate kinase 15128480301128507830Rat
1304972StilSTIL, centriolar assembly protein5128520837128573732Rat
1306748Tal1TAL bHLH transcription factor 1, erythroid differentiation factor5128586776128600976Rat
41126986LOC120102952uncharacterized LOC1201029525128612314128619258Rat
620952Pdzk1ip1PDZK1 interacting protein 15128618050128623131Rat
41400278Trnap-agg66transfer RNA proline (anticodon AGG) 665128635289128635369Rat
628719Cyp4x1cytochrome P450, family 4, subfamily x, polypeptide 15128651681128683338Rat
628846Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 85128702130128733476Rat
40981232Mcts1-ps1MCTS1, re-initiation and release factor, pseudogene 15128728574128729067Rat
1562603Cyp4a8-ps1cytochrome P450, family 4, subfamily a, polypeptide 8, pseudogene 15128827304128852403Rat
41096017Pkm-ps4pyruvate kinase M1/2, pseudogene 45128906060128907436Rat
41170167H3f3cl1H3 histone, family 3C like 15128921288128921701Rat
2479Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 25128922355128934188Rat

1 to 20 of 1002 rows
1 to 20 of 1334 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
6480632D5Uwm741575127833594127833751Ratregion
38338D5Rat1081855128033842128034027Ratregion
7365009rs10583564305128071929128071929Ratregion
5026786RH1335232025128158643128158846Ratregion
5046088RH1315518955128217728128218623Ratregion
5085044AI2376341365128337806128337942Ratregion
43962D5Got501305128398386128398516Ratregion
5067068AU0479841315128425977128426108Ratregion
7206600Foxd29435128428216128429159Ratregion
7206602Foxe33905128445627128446017Ratregion
39606D5Rat1642125128477950128478162Ratregion
43964D5Got572115128486224128486435Ratregion
36187D5Rat301625128499722128499884Ratregion
5078314RH1402692035128515849128516052Ratregion
5085896AW5358801615128562572128562733Ratregion
5073012RH1371832505128573362128573612Ratregion
60490D5Got512285128579225128579453Ratregion
5081537BE1172641815128592686128592867Ratregion
5042526RH1294881655128600753128600918Ratregion
69561D5Uwm352395128627218128627457Ratregion
1 to 20 of 1334 rows

Peak: (D5Rat106)
Rat AssemblyChrPosition (strand)Source
GRCr85155,581,515 - 155,581,721 (+)Marker Load Pipeline
mRatBN7.25150,298,170 - 150,298,378 (+)MAPPER
Rnor_6.05156,443,753 - 156,443,962NCBI
Rnor_5.05160,193,152 - 160,193,361UniSTS
RGSC_v3.45156,856,641 - 156,856,851RGD
RGSC_v3.45156,856,642 - 156,856,851UniSTS
RGSC_v3.15156,866,681 - 156,866,890RGD
Celera5148,692,037 - 148,692,246UniSTS
RH 3.4 Map4952.12RGD
RH 3.4 Map4952.12UniSTS
RH 2.0 Map5976.2RGD
SHRSP x BN Map588.3499RGD
FHH x ACI Map584.2699RGD
Cytogenetic Map5q36UniSTS


1 to 10 of 73 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
1582230Bw78Body weight QTL 783.20.0016epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)5119085612128034027Rat

1 to 10 of 73 rows


Note Type Note Reference
qtl_cross_type intercross  
qtl_general 8% NaCl diet was started at 12 weeks of age and given for 12 weeks 1581737
qtl_general parental S allele was responsible for increased trait 1581737