Prdm16 (PR/SET domain 16) - Rat Genome Database

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Gene: Prdm16 (PR/SET domain 16) Rattus norvegicus
Analyze
Symbol: Prdm16
Name: PR/SET domain 16
RGD ID: 2324431
Description: Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; histone H3K9 methyltransferase activity; and transcription coactivator activity. Predicted to be involved in several processes, including negative regulation of granulocyte differentiation; positive regulation of cold-induced thermogenesis; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of brown fat cell differentiation; and regulation of DNA-templated transcription. Predicted to be located in aggresome; cytosol; and nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1LL. Orthologous to human PRDM16 (PR/SET domain 16); PARTICIPATES IN histone modification pathway; INTERACTS WITH (S)-nicotine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: histone-lysine N-methyltransferase PRDM16; LOC100366024; LOC103692529; PR domain 16; PR domain containing 16; PR domain containing 16-like; PR domain zinc finger protein 16; PR domain zinc finger protein 16-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85170,162,275 - 170,486,371 (-)NCBIGRCr8
mRatBN7.25164,879,864 - 165,203,986 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5164,880,587 - 165,203,601 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.05171,662,277 - 171,711,561 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,662,277 - 171,710,316 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05175,133,484 - 175,180,206 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5163,089,927 - 163,303,567 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (EXP,ISO)
1,1-dichloroethene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrophenol  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buta-1,3-diene  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
daunorubicin  (ISO)
dexamethasone  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fonofos  (ISO)
fulvestrant  (ISO)
Geniposide  (ISO)
harmine  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
Licarin A  (ISO)
mangiferin  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel atom  (ISO)
nicotine  (EXP,ISO)
nitrofen  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
O-methyleugenol  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
propanal  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP)
tofacitinib  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
aggresome  (IEA,ISO)
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)
transcription repressor complex  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
2. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cohen P, etal., Cell. 2014 Jan 16;156(1-2):304-16. doi: 10.1016/j.cell.2013.12.021.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Harms MJ, etal., Cell Metab. 2014 Apr 1;19(4):593-604. doi: 10.1016/j.cmet.2014.03.007.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12816872   PMID:14656887   PMID:17467076   PMID:17618855   PMID:18483224   PMID:18719582   PMID:19049980   PMID:19050759   PMID:19379700   PMID:19641492   PMID:20007998   PMID:22939622  
PMID:25578880  


Genomics

Comparative Map Data
Prdm16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85170,162,275 - 170,486,371 (-)NCBIGRCr8
mRatBN7.25164,879,864 - 165,203,986 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5164,880,587 - 165,203,601 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.05171,662,277 - 171,711,561 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,662,277 - 171,710,316 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05175,133,484 - 175,180,206 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5163,089,927 - 163,303,567 (-)NCBICelera
Cytogenetic Map5q36NCBI
PRDM16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813,069,203 - 3,438,621 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13,069,168 - 3,438,621 (+)EnsemblGRCh38hg38GRCh38
GRCh3712,985,767 - 3,355,185 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612,975,604 - 3,345,045 (+)NCBINCBI36Build 36hg18NCBI36
Build 3413,008,900 - 3,378,340NCBI
Celera12,184,110 - 2,358,440 (+)NCBICelera
Cytogenetic Map1p36.32NCBI
HuRef12,280,175 - 2,647,923 (+)NCBIHuRef
CHM1_112,973,195 - 3,341,256 (+)NCBICHM1_1
T2T-CHM13v2.012,571,244 - 2,943,423 (+)NCBIT2T-CHM13v2.0
Prdm16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394154,400,579 - 154,721,851 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4154,400,582 - 154,721,330 (-)EnsemblGRCm39 Ensembl
GRCm384154,316,122 - 154,637,360 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4154,316,125 - 154,636,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv374153,690,234 - 154,010,982 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364153,164,092 - 153,372,731 (-)NCBIMGSCv36mm8
Celera4156,598,275 - 156,807,441 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map483.96NCBI
Prdm16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554868,137,531 - 8,327,977 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554868,139,848 - 8,327,788 (-)NCBIChiLan1.0ChiLan1.0
PRDM16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21224,877,659 - 225,250,335 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11223,521,103 - 223,895,049 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011,730,122 - 2,100,636 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112,981,854 - 3,231,741 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12,981,667 - 3,234,251 (+)Ensemblpanpan1.1panPan2
PRDM16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1557,805,951 - 58,018,817 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl557,730,370 - 58,017,976 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha557,715,820 - 58,029,862 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0557,906,183 - 58,220,251 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl557,906,344 - 58,217,945 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1557,897,209 - 58,231,011 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0557,789,743 - 58,103,696 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0558,179,637 - 58,493,763 (+)NCBIUU_Cfam_GSD_1.0
Prdm16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505828,856,802 - 29,063,356 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936737404,846 - 446,985 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936737400,819 - 446,768 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRDM16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl664,704,920 - 65,012,570 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1664,704,181 - 65,012,580 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2659,668,500 - 59,728,409 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRDM16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120128,249,894 - 128,613,842 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605432,530,345 - 32,897,713 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prdm16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248186,978,436 - 7,258,357 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248186,978,436 - 7,258,366 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Prdm16
1240 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:87
Interacting mature miRNAs:95
Transcripts:ENSRNOT00000071280, ENSRNOT00000072059
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

Markers in Region
RH138205  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25165,025,865 - 165,026,095 (+)MAPPERmRatBN7.2
Rnor_6.05171,804,565 - 171,804,794NCBIRnor6.0
Rnor_5.05175,273,064 - 175,273,293UniSTSRnor5.0
RGSC_v3.45171,225,546 - 171,225,775UniSTSRGSC3.4
Celera5163,234,767 - 163,234,996UniSTS
RH 3.4 Map51144.2UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 22 14
Low 43 15 4 13 4 2 2 52 21 41 11 2
Below cutoff 3 36 31 6 31 6 9 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000071280   ⟹   ENSRNOP00000064955
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5171,666,903 - 171,710,315 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000072059   ⟹   ENSRNOP00000067712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5171,666,907 - 171,710,315 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076044   ⟹   ENSRNOP00000068441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5164,883,817 - 165,203,470 (-)Ensembl
Rnor_6.0 Ensembl5171,666,955 - 171,710,312 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000077015   ⟹   ENSRNOP00000068014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5164,880,587 - 165,203,601 (-)Ensembl
Rnor_6.0 Ensembl5171,662,277 - 171,710,316 (-)Ensembl
RefSeq Acc Id: NM_001427303   ⟹   NP_001414232
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,485,804 (-)NCBI
RefSeq Acc Id: XM_039111362   ⟹   XP_038967290
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,369 (-)NCBI
mRatBN7.25164,879,864 - 165,203,984 (-)NCBI
RefSeq Acc Id: XM_039111363   ⟹   XP_038967291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,370 (-)NCBI
mRatBN7.25164,879,864 - 165,203,985 (-)NCBI
RefSeq Acc Id: XM_039111365   ⟹   XP_038967293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,370 (-)NCBI
mRatBN7.25164,879,864 - 165,203,985 (-)NCBI
RefSeq Acc Id: XM_039111366   ⟹   XP_038967294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,371 (-)NCBI
mRatBN7.25164,879,864 - 165,203,986 (-)NCBI
RefSeq Acc Id: XM_039111367   ⟹   XP_038967295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,370 (-)NCBI
mRatBN7.25164,879,864 - 165,203,985 (-)NCBI
RefSeq Acc Id: XM_039111368   ⟹   XP_038967296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,369 (-)NCBI
mRatBN7.25164,879,864 - 165,203,984 (-)NCBI
RefSeq Acc Id: XM_039111370   ⟹   XP_038967298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,367 (-)NCBI
mRatBN7.25164,879,864 - 165,203,983 (-)NCBI
RefSeq Acc Id: XM_063287043   ⟹   XP_063143113
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,370 (-)NCBI
RefSeq Acc Id: XM_063287044   ⟹   XP_063143114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,370 (-)NCBI
RefSeq Acc Id: XM_063287045   ⟹   XP_063143115
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,162,275 - 170,486,370 (-)NCBI
RefSeq Acc Id: ENSRNOP00000068014   ⟸   ENSRNOT00000077015
RefSeq Acc Id: ENSRNOP00000064955   ⟸   ENSRNOT00000071280
RefSeq Acc Id: ENSRNOP00000067712   ⟸   ENSRNOT00000072059
RefSeq Acc Id: ENSRNOP00000068441   ⟸   ENSRNOT00000076044
RefSeq Acc Id: XP_038967294   ⟸   XM_039111366
- Peptide Label: isoform X4
- UniProtKB: A6IUL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967295   ⟸   XM_039111367
- Peptide Label: isoform X5
- UniProtKB: A6IUL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967293   ⟸   XM_039111365
- Peptide Label: isoform X3
- UniProtKB: A6IUL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967291   ⟸   XM_039111363
- Peptide Label: isoform X2
- UniProtKB: A6IUL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967296   ⟸   XM_039111368
- Peptide Label: isoform X7
- UniProtKB: A0A096MJ70 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967290   ⟸   XM_039111362
- Peptide Label: isoform X1
- UniProtKB: A0A096MKA6 (UniProtKB/TrEMBL),   A6IUL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967298   ⟸   XM_039111370
- Peptide Label: isoform X8
- UniProtKB: A0A096MJ70 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143115   ⟸   XM_063287045
- Peptide Label: isoform X10
- UniProtKB: A6IUL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143114   ⟸   XM_063287044
- Peptide Label: isoform X9
- UniProtKB: A6IUL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143113   ⟸   XM_063287043
- Peptide Label: isoform X6
- UniProtKB: A6IUL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414232   ⟸   NM_001427303
- UniProtKB: A6IUL8 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type   SET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MJ70-F1-model_v2 AlphaFold A0A096MJ70 1-1092 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2324431 AgrOrtholog
BioCyc Gene G2FUF-38958 BioCyc
Ensembl Genes ENSRNOG00000045913 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000076044.2 UniProtKB/TrEMBL
  ENSRNOT00000077015.3 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro PRDM16_PR-SET UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
NCBI Gene 100366024 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE PRDM16 UniProtKB/TrEMBL
  PR DOMAIN ZINC FINGER PROTEIN 16 ISOFORM X1 UniProtKB/TrEMBL
  TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
Pfam PRDM2_PR UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Prdm16 PhenoGen
PROSITE SET UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000045913 RatGTEx
SMART SET UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A096MJ70 ENTREZGENE, UniProtKB/TrEMBL
  A0A096MKA6 ENTREZGENE, UniProtKB/TrEMBL
  A6IUL8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Prdm16  PR/SET domain 16  LOC103692529  PR domain zinc finger protein 16-like  Data merged from RGD:9327793 737654 PROVISIONAL
2016-07-27 Prdm16  PR/SET domain 16  Prdm16  PR domain 16  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Prdm16  PR domain 16  Prdm16  PR domain containing 16  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-08-25 LOC103692529  PR domain zinc finger protein 16-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-08-08 Prdm16  PR domain containing 16  LOC100366024  PR domain containing 16-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100366024  PR domain containing 16-like      Symbol and Name status set to provisional 70820 PROVISIONAL