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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2324431
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prdm16
Name: PR/SET domain 16
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prdm16affects methylationISOPrdm16 (Mus musculus)6480464CTDMethamphetamine affects the methylation of PRDM16 promoterPMID:26307267
Prdm16increases expressionISOPrdm16 (Mus musculus)6480464CTDMethamphetamine results in increased expression of PRDM16 mRNAPMID:26307267
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