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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2324431
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prdm16
Name: PR/SET domain 16
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prdm16multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of PRDM16 mRNAPMID:36041667
Prdm16affects methylationISOPRDM16 (Homo sapiens)6480464CTDbisphenol A affects the methylation of PRDM16 genePMID:31601247
Prdm16affects methylationISOPrdm16 (Mus musculus)6480464CTDbisphenol A affects the methylation of PRDM16 promoterPMID:27334623
Prdm16decreases expressionISOPrdm16 (Mus musculus)6480464CTDbisphenol A results in decreased expression of PRDM16 mRNAPMID:32156529
Prdm16decreases methylationISOPrdm16 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of PRDM16 promoterPMID:27312807
Prdm16multiple interactionsISOPRDM16 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of PRDM16 genePMID:31601247
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