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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2324431
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prdm16
Name: PR/SET domain 16
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prdm16affects methylationISOPRDM16 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of PRDM16 3' UTR; Benzo(a)pyrene affects the methylation of PRDM16 intron; Benzo(a)pyrene affects the methylation of PRDM16 promoterPMID:27901495 PMID:30157460
Prdm16affects methylationISOPrdm16 (Mus musculus)6480464CTDBenzo(a)pyrene affects the methylation of PRDM16 intronPMID:27901495
Prdm16decreases expressionISOPRDM16 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of PRDM16 mRNAPMID:32234424
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