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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2324431
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prdm16
Name: PR/SET domain 16
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prdm16affects methylationISOPRDM16 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the methylation of PRDM16 genePMID:28011154
Prdm16increases expressionISOPrdm16 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PRDM16 mRNAPMID:37172768
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