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Gene: Icmt (isoprenylcysteine carboxyl methyltransferase) Rattus norvegicus
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Symbol: Icmt
Name: isoprenylcysteine carboxyl methyltransferase
Description: Exhibits protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity. Involved in C-terminal protein methylation; S-adenosylhomocysteine metabolic process; and S-adenosylmethioninamine metabolic process. Localizes to membrane. Orthologous to human ICMT (isoprenylcysteine carboxyl methyltransferase); PARTICIPATES IN homocysteine metabolic pathway; methionine cycle/metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: farnesyl cysteine carboxyl methyltransferase; fcmt; MGC95322; pcCMT; PPMT; prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methlytransferase; prenylcysteine carboxyl methyltransferase; protein-S-isoprenylcysteine O-methyltransferase
Orthologs:
Homo sapiens (human) : ICMT (isoprenylcysteine carboxyl methyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Icmt (isoprenylcysteine carboxyl methyltransferase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Icmt (isoprenylcysteine carboxyl methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Canis lupus familiaris (dog) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Icmt (isoprenylcysteine carboxyl methyltransferase)
Sus scrofa (pig) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Chlorocebus sabaeus (African green monkey) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Heterocephalus glaber (naked mole-rat) : Icmt (isoprenylcysteine carboxyl methyltransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05169,475,270 - 169,482,031 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,475,270 - 169,482,030 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05173,027,895 - 173,035,370 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,526,961 - 169,533,722 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15169,537,360 - 169,543,425 (+)NCBI
Celera5161,035,644 - 161,042,405 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Icmt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621618
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.