Gene: Toe1 (target of EGR1, exonuclease) Rattus norvegicus
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Symbol: Toe1
Name: target of EGR1, exonuclease
Description: ENCODES a protein that exhibits 3'-5'-exoribonuclease activity (ortholog); poly(A)-specific ribonuclease activity (ortholog); snRNA binding (ortholog); INVOLVED IN RNA phosphodiester bond hydrolysis, exonucleolytic (ortholog); snRNA 3'-end processing (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); familial adenomatous polyposis (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN Cajal body (ortholog); cytoplasm (ortholog); nuclear body (ortholog); INTERACTS WITH acrylamide; bisphenol A; methamphetamine
AGR Description: Predicted to have poly(A)-specific ribonuclease activity and snRNA binding activity; predicted to be involved in RNA phosphodiester bond hydrolysis, exonucleolytic and snRNA 3'-end processing; predicted to localize to the Cajal body and cytoplasm; orthologous to human TOE1 (target of EGR1, exonuclease).
Merged Description: Predicted to have poly(A)-specific ribonuclease activity and snRNA binding activity; predicted to be involved in RNA phosphodiester bond hydrolysis, exonucleolytic and snRNA 3'-end processing; predicted to localize to the Cajal body and cytoplasm; orthologous to human TOE1 (target of EGR1, exonuclease); INTERACTS WITH acrylamide; bisphenol A; methamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC298443; target of EGR1 protein 1; target of EGR1, member 1 (nuclear)
Orthologs:
Homo sapiens (human) : TOE1 (target of EGR1, exonuclease)  HGNC  Alliance
Mus musculus (house mouse) : Toe1 (target of EGR1, member 1 (nuclear))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Toe1 (target of EGR1, exonuclease)
Pan paniscus (bonobo/pygmy chimpanzee) : TOE1 (target of EGR1, exonuclease)
Canis lupus familiaris (dog) : TOE1 (target of EGR1, exonuclease)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Toe1 (target of EGR1, exonuclease)
Sus scrofa (pig) : TOE1 (target of EGR1, exonuclease)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05135,659,733 - 135,663,299 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05139,456,024 - 139,459,589 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,100,321 - 137,103,886 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15137,105,561 - 137,108,984 (-)NCBI
Celera5128,797,155 - 128,800,720 (-)NCBICelera
Cytogenetic Map5q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Toe1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309094
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.