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Gene: Pafah2 (platelet-activating factor acetylhydrolase 2) Rattus norvegicus
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Symbol: Pafah2
Name: platelet-activating factor acetylhydrolase 2
Description: Exhibits 1-alkyl-2-acetylglycerophosphocholine esterase activity. Involved in negative regulation of apoptotic process. Predicted to localize to the endoplasmic reticulum membrane and mitochondrial membrane. Orthologous to human PAFAH2 (platelet activating factor acetylhydrolase 2); PARTICIPATES IN ether lipid metabolic pathway; ether lipid metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: platelet-activating factor acetylhydrolase 2 40kDa; platelet-activating factor acetylhydrolase 2, 40kDa; platelet-activating factor acetylhydrolase 2, cytoplasmic; SD-PLA2; serine-dependent phospholipase A2
Orthologs:
Homo sapiens (human) : PAFAH2 (platelet activating factor acetylhydrolase 2)  HGNC  Alliance
Mus musculus (house mouse) : Pafah2 (platelet-activating factor acetylhydrolase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pafah2 (platelet activating factor acetylhydrolase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PAFAH2 (platelet activating factor acetylhydrolase 2)
Canis lupus familiaris (dog) : PAFAH2 (platelet activating factor acetylhydrolase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pafah2 (platelet activating factor acetylhydrolase 2)
Sus scrofa (pig) : PAFAH2 (platelet activating factor acetylhydrolase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05152,606,850 - 152,635,956 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05156,390,608 - 156,419,237 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,157,638 - 153,178,179 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15153,167,676 - 153,188,218 (+)NCBI
Celera5145,029,049 - 145,049,591 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pafah2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631399
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.