Pafah2 (platelet-activating factor acetylhydrolase 2)

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Gene: Pafah2 (platelet-activating factor acetylhydrolase 2) Rattus norvegicus

Analyze

Symbol:

Pafah2

Name:

platelet-activating factor acetylhydrolase 2

RGD ID:

631399

Description:

Exhibits 1-alkyl-2-acetylglycerophosphocholine esterase activity. Involved in negative regulation of apoptotic process. Predicted to localize to endoplasmic reticulum membrane and mitochondrial membrane. Orthologous to human PAFAH2 (platelet activating factor acetylhydrolase 2); PARTICIPATES IN ether lipid metabolic pathway; ether lipid metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; acetamide; ammonium chloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

platelet-activating factor acetylhydrolase 2 40kDa; platelet-activating factor acetylhydrolase 2, 40kDa; platelet-activating factor acetylhydrolase 2, cytoplasmic; SD-PLA2; serine-dependent phospholipase A2

Orthologs:

Homo sapiens (human) : PAFAH2 (platelet activating factor acetylhydrolase 2) HGNC Alliance
Mus musculus (house mouse) : Pafah2 (platelet-activating factor acetylhydrolase 2) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pafah2 (platelet activating factor acetylhydrolase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PAFAH2 (platelet activating factor acetylhydrolase 2)
Canis lupus familiaris (dog) : PAFAH2 (platelet activating factor acetylhydrolase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pafah2 (platelet activating factor acetylhydrolase 2)
Sus scrofa (pig) : PAFAH2 (platelet activating factor acetylhydrolase 2)
Chlorocebus sabaeus (African green monkey) : PAFAH2 (platelet activating factor acetylhydrolase 2)
Heterocephalus glaber (naked mole-rat) : Pafah2 (platelet activating factor acetylhydrolase 2)

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	5	152,606,850 - 152,635,956 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	152,606,847 - 152,634,803 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	156,390,608 - 156,419,237 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	153,157,638 - 153,178,179 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	153,167,676 - 153,188,218 (+)	NCBI
Celera	5	145,029,049 - 145,049,591 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

8-epi-prostaglandin F2alpha (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

butanal (ISO)

carbon nanotube (ISO)

choline (ISO)

clofibrate (ISO)

cocaine (EXP)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

folic acid (ISO)

indole-3-methanol (EXP)

isotretinoin (ISO)

L-methionine (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

N-methyl-N-nitrosourea (ISO)

N-nitrosodiethylamine (EXP)

paracetamol (ISO)

phosphatidylcholine (ISO)

pirinixic acid (ISO)

sodium fluoride (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid catabolic process (IEA)

negative regulation of apoptotic process (IMP)

Cellular Component

cytoplasm (ISS)

endoplasmic reticulum membrane (IEA)

mitochondrial membrane (IEA)

Molecular Function

1-alkyl-2-acetylglycerophosphocholine esterase activity (IBA,IDA,IEA,IMP,ISS)

platelet-activating factor acetyltransferase activity (IDA)

Molecular Pathway Annotations Click to see Annotation Detail View

ether lipid metabolic pathway (IEA)

References

References - curated


1.	Bonin F, etal., J Biol Chem 2004 Dec 10;279(50):52425-36. Epub 2004 Sep 28.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA data from the GO Consortium
4.	Karasawa K, etal., J Biol Chem. 1999 Mar 26;274(13):8655-61. doi: 10.1074/jbc.274.13.8655.
5.	Pipeline to import KEGG annotations from KEGG into RGD
6.	RGD automated data pipeline
7.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Pafah2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	5	152,606,850 - 152,635,956 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	152,606,847 - 152,634,803 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	156,390,608 - 156,419,237 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	153,157,638 - 153,178,179 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	153,167,676 - 153,188,218 (+)	NCBI
Celera	5	145,029,049 - 145,049,591 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

PAFAH2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	25,959,767 - 25,998,117 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	25,959,764 - 25,998,164 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	26,286,258 - 26,326,366 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	26,158,845 - 26,197,235 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	1	25,971,456 - 26,008,790	NCBI
Celera	1	24,682,324 - 24,720,714 (-)	NCBI
Cytogenetic Map	1	p36.11	NCBI
HuRef	1	24,540,816 - 24,578,700 (-)	NCBI		HuRef
CHM1_1	1	26,399,480 - 26,437,894 (-)	NCBI		CHM1_1

Pafah2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	134,123,631 - 134,154,723 (+)	NCBI
GRCm38	4	134,396,320 - 134,427,412 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	134,396,320 - 134,427,413 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	133,952,275 - 133,983,327 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	4	133,669,545 - 133,699,484 (+)	NCBI			mm8
Celera	4	132,570,680 - 132,602,137 (+)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI

Pafah2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	5,440,341 - 5,475,105 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	5,440,766 - 5,474,483 (-)	NCBI	ChiLan1.0	ChiLan1.0

PAFAH2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	26,284,649 - 26,322,693 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	26,284,649 - 26,323,031 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	25,218,632 - 25,256,751 (-)	NCBI

PAFAH2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	2	73,963,360 - 73,994,127 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	2	73,963,313 - 73,994,901 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Pafah2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936474	10,523,605 - 10,554,868 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PAFAH2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	83,411,553 - 83,446,834 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	83,413,513 - 83,446,967 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	77,049,137 - 77,082,468 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PAFAH2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	20	106,771,173 - 106,810,420 (+)	Ensembl
ChlSab1.1	20	106,771,206 - 106,833,670 (+)	NCBI

Pafah2
(Heterocephalus glaber - naked mole-rat)

No map positions available.

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40777918	154732375	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	47745646	167946134	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	61612600	168109659	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	71552569	157225114	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	84963058	173504662	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	100723739	153577831	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	102945579	154732228	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	111278451	156278451	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	112279412	157279412	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	112279412	157279412	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	112279412	157279412	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	112279412	157279412	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	112279412	157279412	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	114140832	159140832	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	114140832	159140832	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	116767924	161767924	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	116767924	161767924	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	116767924	161767924	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	116767924	161767924	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	125455818	157225114	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	128687766	173687766	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	131077716	173707219	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132551937	173707219	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133943857	173707219	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133943857	173707219	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	134197905	173707219	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	134502140	157212422	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	134712342	173707219	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	134712342	173707219	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	136354114	173707219	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136640731	173707219	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138154677	172402610	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	142307322	173707219	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	142309061	173707219	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	149029982	173687766	Rat
2302369	Scl60	Serum cholesterol level QTL 60	3.13		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	149568588	167739697	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	149832180	164807402	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	150340838	164298744	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	150360936	167946134	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	39
Count of miRNA genes:	37
Interacting mature miRNAs:	39
Transcripts:	ENSRNOT00000037097
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			5						10	35	15	11
Low	3	43	52	41	19	41	8	11	64		26		8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_177932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001837842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAHX01040183	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC099104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY225592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000037097 ⟹ ENSRNOP00000034439

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	152,613,255 - 152,633,795 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089070 ⟹ ENSRNOP00000068571

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	152,606,847 - 152,634,803 (+)	Ensembl

RefSeq Acc Id:

NM_177932 ⟹ NP_808793

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	152,613,255 - 152,633,795 (+)	NCBI
Rnor_5.0	5	156,390,608 - 156,419,237 (+)	NCBI
RGSC_v3.4	5	153,157,638 - 153,178,179 (+)	RGD
Celera	5	145,029,049 - 145,049,591 (+)	RGD

Sequence:

show sequence

CAGCTGGTGATGAGATGGGGGCCGGTCAGTCTATATGCTTCCCGCCCATCTCCGGGCCCCACCA
CATTGGCTGCACGGATGTGATGGAGGGTCACAGTCTTGAGGGGAGCCTCTTCCGACTCTTCTAC
CCCTGCGAAGCATCAGAGACGTGCGAGCAGCCCCTGTGGATTCCCCGCTATGAGTACTGCGTGG
GTCTGGCTGACTACCTGCAGTATAACAAGCGCTGGGTGGGGCTGCTGTTCAACGTGGGCATCGG
ATCCTGTCGCTTGCCTGTTAGCTGGAACGGCCCCTTTAAGACAAAGGAATCTGGATACCCTTTG
ATCATCTTGTCCCATGGCCTAGGGGGCTTCAGGGTGTCATACTCGGCCTTCTGCATGGAGCTGG
CCTCCCGTGGCTTTGTGGTTGCTGCCATAGAGCACAGGGACCAGTCAGCTGCAGCCACCTACTT
CTGCAAGCAGACCTCCCAGGAGAGTTCGCCCACTGAGTCTCTGGAGGAGGAATGGATCCCCTTC
CGTCGGATCAAGGAAGGGGAGAAGGAATTCCATGTTAGGAATCCCCAGGTGCACCAGCGGGCGA
AAGAGTGTGTGCGCGTGCTGCAGATCCTTCAGGACGCCTCTGCTGGCAAGCCTGTCATCAATGT
CTTCCCAGGAGGACTGGATCTGATGACCTTGAAGGGCAGCATCGACATGAGCCGAGTGGCTGTG
ATGGGACACTCCTTCGGAGGGGCTACGGCTATTCTTGCTTTGACCCAGGAGGCCCAGTTTCGGT
GTGCTATAGCCCTGGACGCTTGGATGTTCCCTCTGGAACACGACTTCTACCCCAAGGCCCGGGG
CCCCGTGTTCTTTATAAACGTTGAGAAATTCCAGACAGTGGAGAGCGTGAACTTGATGAAGAAG
ATATGTGCCCAGCACGAGCAATCCAGGATCGTGACTGTCCTAGGCGCTGTTCATCGGAGTCAAA
CTGACTTTGCCTTTGTCACGGGCAACATGATTGGTAAACTCTTTTCCAGCGGCACACGTGGGAC
TTTGGACCCTTATGAAGGTCAGGAAGTCATGGTGCGGGCCATGTTGGCCTTCCTGCAGAAGCAC
CTCGACCTGAAGGAGGACTATGATCAGTGGAACAGCTTCATCGAAGGCATCGGACCGTCGCTCA
TCCAAGGGGCCCCACACTATCTGTCCAGCCTCTAGGTTG

hide sequence

RefSeq Acc Id:

XM_006239127 ⟹ XP_006239189

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	152,606,852 - 152,635,956 (+)	NCBI
Rnor_5.0	5	156,390,608 - 156,419,237 (+)	NCBI

Sequence:

show sequence

AGACACCAGGGGGCGCAATCTCACCTGGTCTTGGCTGATTTCACGCCGCCCCAGGGTGTAGTCA
GGAAACCTGGGAATTGTAGTCCTGGAAATGATAAGGCGCCGCGTTGTGTCCCGGGACTTGTAGT
GTACATTTAGAGACAGGGAACGAGTTTAAGTTCGCAGGTTAAGTGAAAGAACTAGTATTCCCAG
AGGCCCACGGGCTCCTGGGCGGTGCCGGGTTTCTGTGGAGTGACCCTTCTGAGGTTGCCTTTGA
ATGATCAGCGTGACTGGCCAGCAAGTTCCTGAGCACCCGCCTTTGGTTCAGCTGGTGATGAGAT
GGGGGCCGGTCAGTCTATATGCTTCCCGCCCATCTCCGGGCCCCACCACATTGGCTGCACGGAT
GTGATGGAGGGTCACAGTCTTGAGGGGAGCCTCTTCCGACTCTTCTACCCCTGCGAAGCATCAG
AGACGTGCGAGCAGCCCCTGTGGATTCCCCGCTATGAGTACTGCGTGGGTCTGGCTGACTACCT
GCAGTATAACAAGCGCTGGGTGGGGCTGCTGTTCAACGTGGGCATCGGATCCTGTCGCTTGCCT
GTTAGCTGGAACGGCCCCTTTAAGACAAAGGAATCTGGATACCCTTTGATCATCTTGTCCCATG
GCCTAGGGGGCTTCAGGGTGTCATACTCGGCCTTCTGCATGGAGCTGGCCTCCCGTGGCTTTGT
GGTTGCTGCCATAGAGCACAGGGACCAGTCAGCTGCAGCCACCTACTTCTGCAAGCAGACCTCC
CAGGAGAGTTCGCCCACTGAGTCTCTGGAGGAGGAATGGATCCCCTTCCGTCGGATCAAGGAAG
GGGAGAAGGAATTCCATGTTAGGAATCCCCAGGTGCACCAGCGGGCGAAAGAGTGTGTGCGCGT
GCTGCAGATCCTTCAGGACGCCTCTGCTGGCAAGCCTGTCATCAATGTCTTCCCAGGAGGACTG
GATCTGATGACCTTGAAGGGCAGCATCGACATGAGCCGAGTGGCTGTGATGGGACACTCCTTCG
GAGGGGCTACGGCTATTCTTGCTTTGACCCAGGAGGCCCAGTTTCGGTGTGCTATAGCCCTGGA
CGCTTGGATGTTCCCTCTGGAACACGACTTCTACCCCAAGGCCCGGGGCCCCGTGTTCTTTATA
AACGTTGAGAAATTCCAGACAGTGGAGAGCGTGAACTTGATGAAGAAGATATGTGCCCAGCACG
AGCAATCCAGGATCGTGACTGTCCTAGGCGCTGTTCATCGGAGTCAAACTGACTTTGCCTTTGT
CACGGGCAACATGATTGGTAAACTCTTTTCCAGCGGCACACGTGGGACTTTGGACCCTTATGAA
GGTCAGGAAGTCATGGTGCGGGCCATGTTGGCCTTCCTGCAGAAGCACCTCGACCTGAAGGAGG
ACTATGATCAGTGGAACAGCTTCATCGAAGGCATCGGACCGTCGCTCATCCAAGGGGCCCCACA
CTATCTGTCCAGCCTCTAGGTTGCTTGACCTGAGTTTTCACTTAGGAGCTGCCCAGGGATACTT
GCAACCTATTGGCAGGACCTTTCTCCCCAGAATGAGAAGATATATATATAATCAGAGCGCTGAC
TGGGCAACCGGATACTCTGCCCTTGGGATTGTTGATCTTAAATGCACCTCAGAACAGATTGTGG
ATGGTCGCTGGCTGATTGGGAAGCTGATTTTTTTTTTTTAAAGTCAAGGACTCGTGACCCAGAC
TGGCTCTGAACTTACTGCATAACGAGGATGGCCTTCTTTCTGAATGACAGACATTACCACCAGG
CCTGGCTGGTATTCAGTGCTGGGGATTGGAACTGATGCGAGTCACTGTGCTGGACTAGACTTAA
AGACTACGAAGTGCTTAGGTGCTGAGGCCCTGTTCTCGGTAGTCCCCACCTCTGTCCCGGGTTT
GCCTTAAGTAAGAACAGTGTTTATCTGCTCAGCCGAGTTCTCTCTTGGCTTGGGCCATTTCTAA
TATTCCAGCCATGCAATTTATCATGTGGAACCCTTACCACTAGGTGCCATTCCCTCTGTGCCAC
CATAACCCCACGGCCAGTCTTTTTGGCATCCCAGAGCACATCTCAAGGAAAACACACTGGCCCT
GTGGCACCTACTTTGGACTGACTTTACAGTGAAGGCTGGGCAGACCACTGTACTAACTGACCAC
ATCCCCCACTCTCGGCAAGCTAACTTTCTTAGGCTGAACTGAGAGACTCAGTCATAGGCTGAGA
CTGGCTGAACCCCCCCAAGCCCCAGGCGGAGCCCCATGGAGCCTGAATATGACAACTTGGCTGG
GCGAGCCCACTCTCTCACCTTGGGCAATTGTTGCTTCCTGAAGCCAAAGGCCTGACAGACACCT
TAGGGCTTCCAGCCCTGCCTGGTGCTCTCCACATGCCCTCTCTCTCTCTCTCCAGGGCAGTCTT
CTCACTGTGTGAAATATAGTAGTGGACACTTTTTTTACTGTCATGCTTAGAAGCCCATGTAGGG
CAGACAGTATTGTCCTCAAAACACAGACACCAAGAAGCCCCTCAGAGGCTCAGTGTCTTTGAGA
TCTCCCAAGTATTTCTTGTCAGGAAACATCCTGAGTGAGTTGAGATGGGCTTGAACTATTAACA
GAGCGGAGTTGCCATTTGCACAGACCTCAGAGGGCACCGGGTTGGCCAGCTCAAATCCAGGAAT
GTTCTAGAGAAGTCTGAGGGCAGCTTGGTCTTGCCTCTTATTCCAAACCAGGGTGCTTTAGTTG
TCTGTCTTGCTTTGTTTCTGGTTTTGTTTTTCCTTTTCCTTTTTTCTTTTTTTCTTTTCTTTTT
TTTTTTTTTTTTGAGGCTATCCCCCAATTTAAGTCAAGGAACAGATCCAGCCTGTTTCATCCTG
TTTCACTGAATAGTGATGCTCATGTTGGCCTTCGGGCTCGCTGTAATTTCATCTGTTTAATTGA
CATTAGAGCGAGTTGGAGAACCATCTGGAAGTCACTTTCCTGATTCTCTTTGTTTGCTAATCGT
GTGCCCTGTGGAAAATGAAATCTTCCCAGAGTTCCAAGTCCAGTGAGAAGGCTCACCTAGGACT
GTACCTCTGCCACACAAGAGAAGTCACCTGAGTCCAAGGAGGGAAGAACCCCGGAGAGGCAAGT
ACAGAATGGAGACGTATCCCTGCACAGTAGTCCAAGGTCAGGGCCAGCAAAGCAATCCAAAGGG
ACGCGCATACATCGGGAGGCTCCTCAGGCTCCGTTCCGCAGCTGCACGACTGGGCGTGGAGTTC
TGGCTTCACCACTGCATCGATCGGAGCAAATTCTGTTGTCTTCCCAACCTCCATTACGAATGGT
CGGAATGATCGAGTGAAGAGATGGATAATCCCCGGGTTCTTAAATGAGCGTTCCCCACGCCCCA
CACATGTGCTTTCTTTTTTCTTTTTTCTTTTTTTTTTTTTTTTTGGTTCTTTTTTTCCGGAGCT
GGGGACCGAACCCAGGGCCTTGCGCTTTCTAGGTAAGCGCTCTACCACTGAGCTAAATCCCCAG
CCCCACGCATGTGCTTTCTAATTGTATGTTCAATGTTTCCCGTCAGAAAGATCTGTATGATCGC
TACACTCCAAGATTTGTTGGAACGTGATTGTTCGCCCACTCACTGTATGATTAAAAAGTATTTT
TTTCTGAA

hide sequence

RefSeq Acc Id:

XM_017593404 ⟹ XP_017448893

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	152,606,851 - 152,635,956 (+)	NCBI

Sequence:

show sequence

CAGACACCAGGGGGCGCAATCTCACCTGGTCTTGGCTGATTTCACGCCGCCCCAGGGTGTAGTC
AGGAAACCTGGGAATTGTAGTCCTGGAAATGATAAGGCGCCGCGTTGTGTCCCGGGACTTGTAG
TGTACATTTAGAGACAGGGAACGAGTTTAAGTTCGCAGGTTAAGTGAAAGAACTAGTATTCCCA
GAGGCCCACGGGCTCCTGGGCGGTGCCGGGTTTCTGTGGAGTGACCCTTCTGAGGTTGCCTTTG
AATGATCAGCGTGACTGGGTTTTGAGGGATCTGAGGCTCATCACCACCGTCTCCTCACCCCACC
AGAAGGAAATGAAGACTACAGTGCTCGGGGCTGGGAATGGAGTGGGTCACTAGCATATGTAAGG
CTCCCAGCTTCCTTCCCACCACTGCAGAAAGACAACAGAAGGATCAGCCTGTAAACGGAAAGTA
GCAAACGTAAATAATGCGTGCGCTTCAGTGAGTAGCTGGCAGGAAGGTCAGTTGGGGTGATAAG
GATGTCAGGAAGTACACAGGGTTGGCACATGACCTAGAGAAACAACAAGCGAGGAAGAGACCAG
CAGGAGGCTGTTCTGCGCTCTGCCTTCCAGCCAGCAAGTTCCTGAGCACCCGCCTTTGGTTCAG
CTGGTGATGAGATGGGGGCCGGTCAGTCTATATGCTTCCCGCCCATCTCCGGGCCCCACCACAT
TGGCTGCACGGATGTGATGGAGGGTCACAGTCTTGAGGGGAGCCTCTTCCGACTCTTCTACCCC
TGCGAAGCATCAGAGACGTGCGAGCAGCCCCTGTGGATTCCCCGCTATGAGTACTGCGTGGGTC
TGGCTGACTACCTGCAGTATAACAAGCGCTGGGTGGGGCTGCTGTTCAACGTGGGCATCGGATC
CTGTCGCTTGCCTGTTAGCTGGAACGGCCCCTTTAAGACAAAGGAATCTGGATACCCTTTGATC
ATCTTGTCCCATGGCCTAGGGGGCTTCAGGGTGTCATACTCGGCCTTCTGCATGGAGCTGGCCT
CCCGTGGCTTTGTGGTTGCTGCCATAGAGCACAGGGACCAGTCAGCTGCAGCCACCTACTTCTG
CAAGCAGACCTCCCAGGAGAGTTCGCCCACTGAGTCTCTGGAGGAGGAATGGATCCCCTTCCGT
CGGATCAAGGAAGGGGAGAAGGAATTCCATGTTAGGAATCCCCAGGTGCACCAGCGGGCGAAAG
AGTGTGTGCGCGTGCTGCAGATCCTTCAGGACGCCTCTGCTGGCAAGCCTGTCATCAATGTCTT
CCCAGGAGGACTGGATCTGATGACCTTGAAGGGCAGCATCGACATGAGCCGAGTGGCTGTGATG
GGACACTCCTTCGGAGGGGCTACGGCTATTCTTGCTTTGACCCAGGAGGCCCAGTTTCGGTGTG
CTATAGCCCTGGACGCTTGGATGTTCCCTCTGGAACACGACTTCTACCCCAAGGCCCGGGGCCC
CGTGTTCTTTATAAACGTTGAGAAATTCCAGACAGTGGAGAGCGTGAACTTGATGAAGAAGATA
TGTGCCCAGCACGAGCAATCCAGGATCGTGACTGTCCTAGGCGCTGTTCATCGGAGTCAAACTG
ACTTTGCCTTTGTCACGGGCAACATGATTGGTAAACTCTTTTCCAGCGGCACACGTGGGACTTT
GGACCCTTATGAAGGTCAGGAAGTCATGGTGCGGGCCATGTTGGCCTTCCTGCAGAAGCACCTC
GACCTGAAGGAGGACTATGATCAGTGGAACAGCTTCATCGAAGGCATCGGACCGTCGCTCATCC
AAGGGGCCCCACACTATCTGTCCAGCCTCTAGGTTGCTTGACCTGAGTTTTCACTTAGGAGCTG
CCCAGGGATACTTGCAACCTATTGGCAGGACCTTTCTCCCCAGAATGAGAAGATATATATATAA
TCAGAGCGCTGACTGGGCAACCGGATACTCTGCCCTTGGGATTGTTGATCTTAAATGCACCTCA
GAACAGATTGTGGATGGTCGCTGGCTGATTGGGAAGCTGATTTTTTTTTTTTAAAGTCAAGGAC
TCGTGACCCAGACTGGCTCTGAACTTACTGCATAACGAGGATGGCCTTCTTTCTGAATGACAGA
CATTACCACCAGGCCTGGCTGGTATTCAGTGCTGGGGATTGGAACTGATGCGAGTCACTGTGCT
GGACTAGACTTAAAGACTACGAAGTGCTTAGGTGCTGAGGCCCTGTTCTCGGTAGTCCCCACCT
CTGTCCCGGGTTTGCCTTAAGTAAGAACAGTGTTTATCTGCTCAGCCGAGTTCTCTCTTGGCTT
GGGCCATTTCTAATATTCCAGCCATGCAATTTATCATGTGGAACCCTTACCACTAGGTGCCATT
CCCTCTGTGCCACCATAACCCCACGGCCAGTCTTTTTGGCATCCCAGAGCACATCTCAAGGAAA
ACACACTGGCCCTGTGGCACCTACTTTGGACTGACTTTACAGTGAAGGCTGGGCAGACCACTGT
ACTAACTGACCACATCCCCCACTCTCGGCAAGCTAACTTTCTTAGGCTGAACTGAGAGACTCAG
TCATAGGCTGAGACTGGCTGAACCCCCCCAAGCCCCAGGCGGAGCCCCATGGAGCCTGAATATG
ACAACTTGGCTGGGCGAGCCCACTCTCTCACCTTGGGCAATTGTTGCTTCCTGAAGCCAAAGGC
CTGACAGACACCTTAGGGCTTCCAGCCCTGCCTGGTGCTCTCCACATGCCCTCTCTCTCTCTCT
CCAGGGCAGTCTTCTCACTGTGTGAAATATAGTAGTGGACACTTTTTTTACTGTCATGCTTAGA
AGCCCATGTAGGGCAGACAGTATTGTCCTCAAAACACAGACACCAAGAAGCCCCTCAGAGGCTC
AGTGTCTTTGAGATCTCCCAAGTATTTCTTGTCAGGAAACATCCTGAGTGAGTTGAGATGGGCT
TGAACTATTAACAGAGCGGAGTTGCCATTTGCACAGACCTCAGAGGGCACCGGGTTGGCCAGCT
CAAATCCAGGAATGTTCTAGAGAAGTCTGAGGGCAGCTTGGTCTTGCCTCTTATTCCAAACCAG
GGTGCTTTAGTTGTCTGTCTTGCTTTGTTTCTGGTTTTGTTTTTCCTTTTCCTTTTTTCTTTTT
TTCTTTTCTTTTTTTTTTTTTTTTTGAGGCTATCCCCCAATTTAAGTCAAGGAACAGATCCAGC
CTGTTTCATCCTGTTTCACTGAATAGTGATGCTCATGTTGGCCTTCGGGCTCGCTGTAATTTCA
TCTGTTTAATTGACATTAGAGCGAGTTGGAGAACCATCTGGAAGTCACTTTCCTGATTCTCTTT
GTTTGCTAATCGTGTGCCCTGTGGAAAATGAAATCTTCCCAGAGTTCCAAGTCCAGTGAGAAGG
CTCACCTAGGACTGTACCTCTGCCACACAAGAGAAGTCACCTGAGTCCAAGGAGGGAAGAACCC
CGGAGAGGCAAGTACAGAATGGAGACGTATCCCTGCACAGTAGTCCAAGGTCAGGGCCAGCAAA
GCAATCCAAAGGGACGCGCATACATCGGGAGGCTCCTCAGGCTCCGTTCCGCAGCTGCACGACT
GGGCGTGGAGTTCTGGCTTCACCACTGCATCGATCGGAGCAAATTCTGTTGTCTTCCCAACCTC
CATTACGAATGGTCGGAATGATCGAGTGAAGAGATGGATAATCCCCGGGTTCTTAAATGAGCGT
TCCCCACGCCCCACACATGTGCTTTCTTTTTTCTTTTTTCTTTTTTTTTTTTTTTTTGGTTCTT
TTTTTCCGGAGCTGGGGACCGAACCCAGGGCCTTGCGCTTTCTAGGTAAGCGCTCTACCACTGA
GCTAAATCCCCAGCCCCACGCATGTGCTTTCTAATTGTATGTTCAATGTTTCCCGTCAGAAAGA
TCTGTATGATCGCTACACTCCAAGATTTGTTGGAACGTGATTGTTCGCCCACTCACTGTATGAT
TAAAAAGTATTTTTTTCTGAA

hide sequence

RefSeq Acc Id:

XR_001837842

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	152,606,850 - 152,633,785 (+)	NCBI

Sequence:

show sequence

TCAGACACCAGGGGGCGCAATCTCACCTGGTCTTGGCTGATTTCACGCCGCCCCAGGGTGTAGT
CAGGAAACCTGGGAATTGTAGTCCTGGAAATGATAAGGCGCCGCGTTGTGTCCCGGGACTTGTA
GTGTACATTTAGAGACAGGGAACGAGTTTAAGTTCGCAGGTTAAGTGAAAGAACTAGTATTCCC
AGAGGCCCACGGGCTCCTGGGCGGTGCCGGGTTTCTGTGGAGTGACCCTTCTGAGGTTGCCTTT
GAATGATCAGCGTGACTGGCCAGCAAGTTCCTGAGCACCCGCCTTTGGTTCAGCTGGTGATGAG
ATGGGGGCCGGTCAGTCTATATGCTTCCCGCCCATCTCCGGGCCCCACCACATTGGCTGCACGG
ATGTGATGGAGGGTCACAGTCTTGAGGGGAGCCTCTTCCGACTCTTCTACCCCTGCGAAGCATC
AGAGACGTGCGAGCAGCCCCTGTGGATTCCCCGCTATGAGTACTGCGTGGGTCTGGCTGACTAC
CTGCAGTATAACAAGCGCTGGGTGGGGCTGCTGTTCAACGTGGGCATCGGATCCTGTCGCTTGC
CTGTTAGCTGGAACGGCCCCTTTAAGACAAAGGAATCTGGATACCCTTTGATCATCTTGTCCCA
TGGCCTAGGGGGCTTCAGGGTGTCATACTCGGCCTTCTGCATGGAGCTGGCCTCCCGTGGCTTT
GTGGTTGCTGCCATAGAGCACAGGGACCAGTCAGCTGCAGCCACCTACTTCTGCAAGCAGACCT
CCCAGGAGAGTTCGCCCACTGAGTCTCTGGAGGAGGAATGGATCCCCTTCCGTCGGATCAAGGA
AGGGGAGAAGGAATTCCATGTTAGGAATCCCCAGGTGCACCAGCGGGCGAAAGAGTGTGTGCGC
GTGCTGCAGATCCTTCAGGACGCCTCTGCTGGCAAGCCTGTCATCAATGTCTTCCCAGGAGGAC
TGGATCTGATGACCTTGAAGGGCAGCATCGACATGAGCCGAGTGGCTGTGATGGGACACTCCTT
CGGAGGGGCTACGGCTATTCTTGCTTTGACCCAGGAGGCCCAGTTTCGGTGTGCTATAGCCCTG
GACGCTTGGATGTTCCCTCTGGAACACGACTTCTACCCCAAGGCCCGGGGCCCCGTGTTCTTTA
TAAACGTTGAGAAATTCCAGACAGTGGAGAGCGTGAACTTGATGAAGAAGATATGTGCCCAGCA
CGAGCAATCCAGGATCGTGACTGTCCTAGGCGCTGTTCATCGGAGTCAAACTGACTTTGCCTTT
GTCACGGGCAACATGATTGGTAAACTCTTTTCCAGCGGCACACGTGGGACTTTGGACCCTTATG
AAGGTCAGGAAGTCATGGTGCGGGCCATGTTGGCCTTCCTGCAGAAGCACCTCGCGTCTGTTTG
TTCACTCTCTGACTCCTCAGAACTTGGCTTAGCTCCTGCCACCGATGGCTGGTTCTCTCCTTGA
GGGTCCACGTCTTCCTCTCCAGAGCCCTCTCTTCACGATGTATTTGAGGGGACCTGAAGGAGGA
CTATGATCAGTGGAACAGCTTCATCGAAGGCATCGGACCGTCGCTCATCCAAGGGGCCCCACAC
TATCTGTCCAGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_808793	(Get FASTA)	NCBI Sequence Viewer
	XP_006239189	(Get FASTA)	NCBI Sequence Viewer
	XP_017448893	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAO62314	(Get FASTA)	NCBI Sequence Viewer
	EDL80720	(Get FASTA)	NCBI Sequence Viewer
	EDL80721	(Get FASTA)	NCBI Sequence Viewer
	P83006	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_808793 ⟸ NM_177932

- UniProtKB:

P83006 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MGAGQSICFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCEASETCEQPLWIPRYEYCVGLADY
LQYNKRWVGLLFNVGIGSCRLPVSWNGPFKTKESGYPLIILSHGLGGFRVSYSAFCMELASRGF
VVAAIEHRDQSAAATYFCKQTSQESSPTESLEEEWIPFRRIKEGEKEFHVRNPQVHQRAKECVR
VLQILQDASAGKPVINVFPGGLDLMTLKGSIDMSRVAVMGHSFGGATAILALTQEAQFRCAIAL
DAWMFPLEHDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAF
VTGNMIGKLFSSGTRGTLDPYEGQEVMVRAMLAFLQKHLDLKEDYDQWNSFIEGIGPSLIQGAP
HYLSSL

hide sequence

RefSeq Acc Id:	XP_006239189 ⟸ XM_006239127
- Peptide Label:	isoform X1
- UniProtKB:	P83006 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGAGQSICFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCEASETCEQPLWIPRYEYCVGLADY LQYNKRWVGLLFNVGIGSCRLPVSWNGPFKTKESGYPLIILSHGLGGFRVSYSAFCMELASRGF VVAAIEHRDQSAAATYFCKQTSQESSPTESLEEEWIPFRRIKEGEKEFHVRNPQVHQRAKECVR VLQILQDASAGKPVINVFPGGLDLMTLKGSIDMSRVAVMGHSFGGATAILALTQEAQFRCAIAL DAWMFPLEHDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAF VTGNMIGKLFSSGTRGTLDPYEGQEVMVRAMLAFLQKHLDLKEDYDQWNSFIEGIGPSLIQGAP HYLSSL hide sequence

RefSeq Acc Id:	XP_017448893 ⟸ XM_017593404
- Peptide Label:	isoform X1
- UniProtKB:	P83006 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGAGQSICFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCEASETCEQPLWIPRYEYCVGLADY LQYNKRWVGLLFNVGIGSCRLPVSWNGPFKTKESGYPLIILSHGLGGFRVSYSAFCMELASRGF VVAAIEHRDQSAAATYFCKQTSQESSPTESLEEEWIPFRRIKEGEKEFHVRNPQVHQRAKECVR VLQILQDASAGKPVINVFPGGLDLMTLKGSIDMSRVAVMGHSFGGATAILALTQEAQFRCAIAL DAWMFPLEHDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAF VTGNMIGKLFSSGTRGTLDPYEGQEVMVRAMLAFLQKHLDLKEDYDQWNSFIEGIGPSLIQGAP HYLSSL hide sequence

RefSeq Acc Id:

ENSRNOP00000068571 ⟸ ENSRNOT00000089070

RefSeq Acc Id:

ENSRNOP00000034439 ⟸ ENSRNOT00000037097

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694137

Promoter ID:

EPDNEW_R4662

Type:

multiple initiation site

Name:

Pafah2_1

Description:

platelet-activating factor acetylhydrolase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	152,607,100 - 152,607,160	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:631399	AgrOrtholog
Ensembl Genes	ENSRNOG00000022288	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000034439	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000068571	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000037097	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000089070	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ac_Ohase_PAF	UniProtKB/Swiss-Prot
	PAF_acetylhydro-like	UniProtKB/TrEMBL
	PAF_acetylhydro_eukaryote	UniProtKB/TrEMBL
	PAF_acetylhydro_II	UniProtKB/Swiss-Prot
KEGG Report	rno:313611	UniProtKB/Swiss-Prot
NCBI Gene	313611	ENTREZGENE
PANTHER	PAF_acetylhydro_II	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	PAF-AH_p_II	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pafah2	PhenoGen
PIRSF	PAF_acetylhydrolase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	LIPASE_SER	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF53474	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene	Rn.92487	ENTREZGENE
UniProt	A0A0G2JT51_RAT	UniProtKB/TrEMBL
	P83006	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q80Z89	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-02-11	Slc1a7	platelet-activating factor acetylhydrolase 2	Pafah2	platelet-activating factor acetylhydrolase 2, 40kDa	Name updated to reflect Human and Mouse nomenclature	625702	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_product	one of three serine esterase isoenzymes that catalyze the inactivation of platelet-activating factor	1540381

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - KEGG (archival)