Isg15 (ISG15 ubiquitin-like modifier) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Isg15 (ISG15 ubiquitin-like modifier) Rattus norvegicus
Analyze
Symbol: Isg15
Name: ISG15 ubiquitin-like modifier
RGD ID: 1310312
Description: Predicted to enable integrin binding activity; protein tag; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including ISG15-protein conjugation; defense response to other organism; and positive regulation of cytokine production. Predicted to act upstream of or within response to bacterium. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 38. Orthologous to human ISG15 (ISG15 ubiquitin like modifier); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: G1p2; interferon, alpha-inducible protein (clone IFI-15K); LOC298693; ubiquitin-like protein ISG15
RGD Orthologs
Human
Mouse
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25166,784,148 - 166,785,435 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,784,148 - 166,785,435 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5169,486,258 - 169,487,543 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05171,307,649 - 171,308,934 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05171,270,210 - 171,271,495 (-)NCBIRnor_WKY
Rnor_6.05173,624,862 - 173,629,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,624,310 - 173,626,248 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05177,098,640 - 177,102,838 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45173,034,479 - 173,035,766 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15173,031,293 - 173,045,496 (-)NCBI
Celera5164,983,801 - 164,985,088 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP,ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
Actein  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alvocidib  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroprene  (EXP)
cholesterol  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
Cuprizon  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dieldrin  (EXP)
diethyl malate  (ISO)
diethylstilbestrol  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
Genipin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
GW 4064  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
lipoteichoic acid  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metam  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mitoxantrone  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP)
nicotine  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentanal  (ISO)
phenylephrine  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
poly(I:C)  (ISO)
prednisolone  (ISO)
propanal  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
senecionine  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium aurothiomalate  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
succimer  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
testosterone enanthate  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tofacitinib  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP,ISO)
trimellitic anhydride  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
XL147  (ISO)
zidovudine  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Differential gene expression pattern of diabetic rat retinas after intravitreal injection of erythropoietin. Chu Q, etal., Clin Experiment Ophthalmol. 2011 Mar;39(2):142-51. doi: 10.1111/j.1442-9071.2010.02437.x.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Hepatic IFNL4 expression is associated with non-response to interferon-based therapy through the regulation of basal interferon-stimulated gene expression in chronic hepatitis C patients. Murakawa M, etal., J Med Virol. 2017 Jul;89(7):1241-1247. doi: 10.1002/jmv.24763. Epub 2017 Feb 27.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15485925   PMID:16122702   PMID:16139798   PMID:17227866   PMID:18305167   PMID:19357168   PMID:21402791   PMID:21543490   PMID:22022510   PMID:22859821   PMID:23012479   PMID:29100055  
PMID:30826466   PMID:31505169  


Genomics

Comparative Map Data
Isg15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25166,784,148 - 166,785,435 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,784,148 - 166,785,435 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5169,486,258 - 169,487,543 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05171,307,649 - 171,308,934 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05171,270,210 - 171,271,495 (-)NCBIRnor_WKY
Rnor_6.05173,624,862 - 173,629,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,624,310 - 173,626,248 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05177,098,640 - 177,102,838 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45173,034,479 - 173,035,766 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15173,031,293 - 173,045,496 (-)NCBI
Celera5164,983,801 - 164,985,088 (-)NCBICelera
Cytogenetic Map5q36NCBI
ISG15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,013,497 - 1,014,540 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl11,001,138 - 1,014,540 (+)EnsemblGRCh38hg38GRCh38
GRCh371948,877 - 949,920 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361938,742 - 939,782 (+)NCBINCBI36Build 36hg18NCBI36
Build 341988,945 - 989,986NCBI
Celera11,639,488 - 1,640,561 (-)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1220,321 - 221,394 (+)NCBIHuRef
CHM1_11935,863 - 936,936 (+)NCBICHM1_1
T2T-CHM13v2.01443,628 - 444,671 (+)NCBIT2T-CHM13v2.0
Isg15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394156,283,881 - 156,285,275 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4156,283,912 - 156,285,253 (-)EnsemblGRCm39 Ensembl
GRCm384156,199,424 - 156,200,818 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4156,199,455 - 156,200,796 (-)EnsemblGRCm38mm10GRCm38
MGSCv374155,573,533 - 155,574,927 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364155,573,561 - 155,574,905 (-)NCBIMGSCv36mm8
Celera4158,455,875 - 158,457,269 (-)NCBICelera
Cytogenetic Map4E2NCBI
Isg15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,706,703 - 9,707,949 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554869,706,878 - 9,707,876 (-)NCBIChiLan1.0ChiLan1.0
ISG15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,230,879 - 56,237,354 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,236,318 - 56,404,695 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,314,175 - 56,315,328 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,439,681 - 56,440,834 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,439,798 - 56,607,588 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,430,725 - 56,431,878 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,322,629 - 56,323,782 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,712,681 - 56,713,834 (+)NCBIUU_Cfam_GSD_1.0
Isg15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,421,189 - 27,422,563 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367372,043,383 - 2,044,761 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ISG15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,363,173 - 63,364,208 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,363,201 - 63,364,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ISG15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,419,909 - 130,421,409 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20130,419,782 - 130,421,380 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605435,047,518 - 35,049,231 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Isg15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248188,510,657 - 8,511,749 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Isg15
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:36
Count of miRNA genes:33
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000039263
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

Markers in Region
RH135070  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,784,161 - 166,784,343 (+)MAPPERmRatBN7.2
Rnor_6.05173,624,916 - 173,625,097NCBIRnor6.0
Rnor_5.05177,098,694 - 177,098,875UniSTSRnor5.0
RGSC_v3.45173,034,493 - 173,034,674UniSTSRGSC3.4
Celera5164,983,815 - 164,983,996UniSTS
RH 3.4 Map51171.5UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 16 5 16 5 5 6 10
Low 3 25 25 20 3 20 8 11 43 18 33 1 8
Below cutoff 16 16 16 16 31 12 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000039263   ⟹   ENSRNOP00000035405
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5173,624,310 - 173,626,248 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096620   ⟹   ENSRNOP00000090709
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5166,784,148 - 166,785,435 (-)Ensembl
RefSeq Acc Id: NM_001106700   ⟹   NP_001100170
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25166,784,148 - 166,785,435 (-)NCBI
Rnor_6.05173,624,902 - 173,626,189 (-)NCBI
Rnor_5.05177,098,640 - 177,102,838 (-)NCBI
RGSC_v3.45173,034,479 - 173,035,766 (-)RGD
Celera5164,983,801 - 164,985,088 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100170 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL81366 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001100170   ⟸   NM_001106700
- UniProtKB: D4A3X3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000035405   ⟸   ENSRNOT00000039263
RefSeq Acc Id: ENSRNOP00000090709   ⟸   ENSRNOT00000096620
Protein Domains
Ubiquitin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3X3-F1-model_v2 AlphaFold D4A3X3 1-161 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694345
Promoter ID:EPDNEW_R4869
Type:multiple initiation site
Name:Isg15_1
Description:ISG15 ubiquitin-like modifier
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05173,626,140 - 173,626,200EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310312 AgrOrtholog
BioCyc Gene G2FUF-38859 BioCyc
Ensembl Genes ENSRNOG00000021802 Ensembl
  ENSRNOG00000069527 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000090709 ENTREZGENE
  ENSRNOP00000090709.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000096620 ENTREZGENE
  ENSRNOT00000096620.1 UniProtKB/TrEMBL
InterPro Ubiquitin UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
NCBI Gene 298693 ENTREZGENE
Pfam ubiquitin UniProtKB/TrEMBL
PhenoGen Isg15 PhenoGen
PROSITE UBIQUITIN_2 UniProtKB/TrEMBL
SMART UBQ UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt D4A3X3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Isg15  ISG15 ubiquitin-like modifier  G1p2  interferon, alpha-inducible protein (clone IFI-15K)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 G1p2  interferon, alpha-inducible protein (clone IFI-15K)   G1p2_predicted  interferon, alpha-inducible protein (clone IFI-15K) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 G1p2_predicted  interferon, alpha-inducible protein (clone IFI-15K) (predicted)      Symbol and Name status set to approved 70820 APPROVED