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Gene: Isg15 (ISG15 ubiquitin-like modifier) Rattus norvegicus
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Symbol: Isg15
Name: ISG15 ubiquitin-like modifier
Description: Predicted to have integrin binding activity; protein tag; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including cellular protein metabolic process; cytokine secretion; and defense response to other organism. Predicted to localize to the cytoplasm; extracellular region; and nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human ISG15 (ISG15 ubiquitin like modifier); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: G1p2; interferon, alpha-inducible protein (clone IFI-15K); LOC298693; ubiquitin-like protein ISG15
Orthologs:
Homo sapiens (human) : ISG15 (ISG15 ubiquitin like modifier)  HGNC  Alliance
Mus musculus (house mouse) : Isg15 (ISG15 ubiquitin-like modifier)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Isg15 (ISG15 ubiquitin like modifier)
Pan paniscus (bonobo/pygmy chimpanzee) : ISG15 (ISG15 ubiquitin like modifier)
Canis lupus familiaris (dog) : ISG15 (ISG15 ubiquitin like modifier)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Isg15 (ISG15 ubiquitin like modifier)
Sus scrofa (pig) : ISG15 (ISG15 ubiquitin like modifier)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05173,624,862 - 173,629,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,624,310 - 173,626,248 (-)Ensembl
Rnor_5.05177,098,640 - 177,102,838 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45173,034,479 - 173,035,766 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15173,031,293 - 173,045,496 (-)NCBI
Celera5164,983,801 - 164,985,088 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Isg15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310312
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.