Stmn1 (stathmin 1) - Rat Genome Database

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Gene: Stmn1 (stathmin 1) Rattus norvegicus
Analyze
Symbol: Stmn1 (Ensembl: LOC102551813)
Name: stathmin 1 (Ensembl:stathmin-like)
RGD ID: 2992
Description: Predicted to enable tubulin binding activity. Predicted to be involved in several processes, including establishment of skin barrier; negative regulation of signal transduction; and regulation of cytoskeleton organization. Predicted to act upstream of or within several processes, including axonogenesis; mitotic spindle organization; and negative regulation of microtubule polymerization. Predicted to be located in cytosol and membrane. Predicted to be active in cytoplasm and neuron projection. Orthologous to human STMN1 (stathmin 1); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Lap18; Leukemia-associated cytosolic phosphoprotein stathmin; leukemia-associated gene; leukemia-associated phosphoprotein p18; metablastin; MGC72884; NOT NULL; oncoprotein 18; OP18; phosphoprotein p19; PP17; PP19; PR22; prosolin; SMN; stathmin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,964,308 - 151,970,843 (+)NCBIGRCr8
mRatBN7.25146,680,757 - 146,687,154 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,681,436 - 146,687,154 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,383,560 - 149,389,224 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05151,153,616 - 151,159,276 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05151,139,803 - 151,145,467 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,680,412 - 152,686,807 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,680,407 - 152,686,806 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,466,632 - 156,472,404 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,226,420 - 153,232,084 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15153,236,461 - 153,242,123 (+)NCBI
Celera5145,096,588 - 145,102,252 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Stmn1Rathepatocellular carcinoma disease_progressionISOSTMN1 (Homo sapiens)21408578 RGD 
Object Symbol
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Reference
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Original Reference(s)
Stmn1Ratautosomal recessive hypercholesterolemia  ISOSTMN1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hypercholesterolemia more ...ClinVarPMID:11326085 more ...
Stmn1Ratretinitis pigmentosa 59  ISOSTMN1 (Homo sapiens)8554872ClinVar Annotator: match by term: Retinitis pigmentosa 59ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Stmn1RatAnimal Mammary Neoplasms  ISOSTMN1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:12376462
Stmn1Ratbasal cell carcinoma  ISOSTMN1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:36428691
Stmn1RatBreast Neoplasms  ISOSTMN1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17659439
Stmn1Ratcarcinoma  ISOSTMN1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:12376462
Stmn1RatExperimental Mammary Neoplasms  ISOSTMN1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:12376462
Stmn1Rathepatocellular carcinoma  ISOSTMN1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28284560
Stmn1Rathigh grade glioma  ISOSTMN1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17440165
Stmn1RatProstatic Neoplasms  ISOSTMN1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17455228

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Object Symbol
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Reference
Notes
Source
Original Reference(s)
Stmn1Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of STMN1 mRNA]CTDPMID:31150632
Stmn1Rat(-)-epigallocatechin 3-gallate decreases expressionISOSTMN1 (Homo sapiens)6480464epigallocatechin gallate results in decreased expression of STMN1 proteinCTDPMID:31195006
Stmn1Rat(1->4)-beta-D-glucan multiple interactionsISOStmn1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of STMN1 mRNACTDPMID:36331819
Stmn1Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expressionISOStmn1 (Mus musculus)6480464o and p'-DDT affects the expression of STMN1 mRNACTDPMID:18925944
Stmn1Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expressionEXP 6480464o and p'-DDT affects the expression of STMN1 mRNACTDPMID:17984292
Stmn1Rat1,2-dimethylhydrazine multiple interactionsISOStmn1 (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of STMN1 mRNA]CTDPMID:22206623
Stmn1Rat1,2-dimethylhydrazine increases expressionISOStmn1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of STMN1 mRNACTDPMID:22206623
Stmn1Rat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactionsISOStmn1 (Mus musculus)6480464Levodopa inhibits the reaction [1-Methyl-4-phenyl-1 more ...CTDPMID:23562983
Stmn1Rat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expressionISOStmn1 (Mus musculus)64804641-Methyl-4-phenyl-1 more ...CTDPMID:23562983
Stmn1Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of STMN1 mRNACTDPMID:30723492
Stmn1Rat17alpha-ethynylestradiol affects expressionISOStmn1 (Mus musculus)6480464Ethinyl Estradiol affects the expression of STMN1 mRNACTDPMID:17555576
Stmn1Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of STMN1 mRNACTDPMID:15834898 and PMID:29097150
Stmn1Rat17alpha-ethynylestradiol multiple interactionsISOStmn1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of STMN1 mRNACTDPMID:17942748
Stmn1Rat17alpha-ethynylestradiol increases expressionISOStmn1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of STMN1 mRNACTDPMID:17942748
Stmn1Rat17beta-estradiol increases expressionISOSTMN1 (Homo sapiens)6480464Estradiol results in increased expression of STMN1 mRNACTDPMID:16474171 more ...
Stmn1Rat17beta-estradiol decreases expressionISOStmn1 (Mus musculus)6480464Estradiol results in decreased expression of STMN1 mRNACTDPMID:39298647
Stmn1Rat17beta-estradiol affects expressionEXP 6480464Estradiol affects the expression of STMN1 mRNACTDPMID:32145629
Stmn1Rat17beta-estradiol decreases phosphorylationISOSTMN1 (Homo sapiens)6480464Estradiol results in decreased phosphorylation of STMN1 proteinCTDPMID:27026707
Stmn1Rat17beta-estradiol decreases expressionISOSTMN1 (Homo sapiens)6480464Estradiol results in decreased expression of STMN1 mRNACTDPMID:23019147 and PMID:31614463
Stmn1Rat2,2',4,4',5,5'-hexachlorobiphenyl increases expressionEXP 64804642 more ...CTDPMID:20959002

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Biological Process
1 to 20 of 36 rows

  
Object Symbol
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Original Reference(s)
Stmn1Rataxonogenesis acts_upstream_of_or_withinISOStmn1 (Mus musculus)1624291MGI:2655259 PMID:11839567RGDPMID:11839567
Stmn1Ratcell differentiation involved_inIEAUniProtKB-KW:KW-02211600115GO_REF:0000043UniProtGO_REF:0000043
Stmn1Ratestablishment of skin barrier involved_inISOSTMN1 (Homo sapiens)1624291 PMID:25198505RGDPMID:25198505
Stmn1Ratestablishment of skin barrier involved_inIEAUniProtKB:P16949 and ensembl:ENSP000003878581600115GO_REF:0000107EnsemblGO_REF:0000107
Stmn1Rathepatocyte growth factor receptor signaling pathway involved_inISOSTMN1 (Homo sapiens)1624291 PMID:25198505RGDPMID:25198505
Stmn1Rathepatocyte growth factor receptor signaling pathway involved_inIEAUniProtKB:P16949 and ensembl:ENSP000003878581600115GO_REF:0000107EnsemblGO_REF:0000107
Stmn1Ratintracellular signal transduction  TAS 61528 RGD 
Stmn1Ratmicrotubule depolymerization involved_inISOSTMN1 (Homo sapiens)1624291 PMID:10675326RGDPMID:10675326
Stmn1Ratmicrotubule depolymerization  TAS 61528 RGD 
Stmn1Ratmicrotubule depolymerization involved_inIBAPANTHER:PTN000802387 and UniProtKB:P169491600115GO_REF:0000033GO_CentralGO_REF:0000033
Stmn1Ratmicrotubule depolymerization acts_upstream_of_or_withinIEAUniProtKB:P16949 and ensembl:ENSP000003878581600115GO_REF:0000107EnsemblGO_REF:0000107
Stmn1Ratmicrotubule depolymerization acts_upstream_of_or_withinISOSTMN1 (Homo sapiens)1624291 PMID:9880330RGDPMID:9880330
Stmn1Ratmitotic cytokinesis involved_inISOSTMN1 (Homo sapiens)1624291 PMID:25122120RGDPMID:25122120
Stmn1Ratmitotic cytokinesis acts_upstream_of_or_withinISOStmn1 (Mus musculus)1624291MGI:1335094 PMID:25122120RGDPMID:25122120
Stmn1Ratmitotic cytokinesis involved_inIEAUniProtKB:P16949 and ensembl:ENSP000003878581600115GO_REF:0000107EnsemblGO_REF:0000107
Stmn1Ratmitotic spindle organization acts_upstream_of_or_withinISOSTMN1 (Homo sapiens)1624291 PMID:9271428RGDPMID:9271428
Stmn1Ratmitotic spindle organization acts_upstream_of_or_withinIEAUniProtKB:P16949 and ensembl:ENSP000003878581600115GO_REF:0000107EnsemblGO_REF:0000107
Stmn1Ratnegative regulation of guanyl-nucleotide exchange factor activity involved_inISOSTMN1 (Homo sapiens)1624291 PMID:25198505RGDPMID:25198505
Stmn1Ratnegative regulation of microtubule polymerization involved_inISOSTMN1 (Homo sapiens)1624291 PMID:25198505RGDPMID:25198505
Stmn1Ratnegative regulation of microtubule polymerization involved_inIEAUniProtKB:P16949 and ensembl:ENSP000003878581600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
1 to 11 of 11 rows

  
Object Symbol
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Evidence
With
Reference
Notes
Source
Original Reference(s)
Stmn1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Stmn1Ratcytoplasm is_active_inIBAMGI:1277137 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Stmn1Ratcytoplasm located_inISOStmn1 (Mus musculus)1624291 PMID:10369391RGDPMID:10369391
Stmn1Ratcytoskeleton located_inIEAUniProtKB-SubCell:SL-00901600115GO_REF:0000044UniProtGO_REF:0000044
Stmn1Ratcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
Stmn1Ratcytosol located_inISOSTMN1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Stmn1Ratcytosol located_inIEAUniProtKB:P16949 and ensembl:ENSP000003878581600115GO_REF:0000107EnsemblGO_REF:0000107
Stmn1Ratcytosol located_inISOStmn1 (Mus musculus)1624291 PMID:10712642RGDPMID:10712642
Stmn1Ratmembrane located_inISOStmn1 (Mus musculus)1624291 PMID:10712642RGDPMID:10712642
Stmn1Ratmicrotubule located_inIEAUniProtKB-KW:KW-04931600115GO_REF:0000043UniProtGO_REF:0000043
Stmn1Ratneuron projection is_active_inIBAMGI:98241 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
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Molecular Function

  

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Stmn1Ratmitogen activated protein kinase signaling pathway   IEA 6907045 KEGGrno:04010

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#
Reference Title
Reference Citation
1. A single cDNA encodes two isoforms of stathmin, a developmentally regulated neuron-enriched phosphoprotein. Doye V, etal., J Biol Chem 1989 Jul 25;264(21):12134-7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network. Gavet O, etal., J Cell Sci 1998 Nov;111 ( Pt 22):3333-46.
4. miR-223 and Stathmin-1 Expression in Non-tumor Liver Tissue of Patients with Hepatocellular Carcinoma. Imura S, etal., Anticancer Res. 2017 Oct;37(10):5877-5883. doi: 10.21873/anticanres.12033.
5. Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth. Kinoshita I, etal., Oncogene 2003 May 8;22(18):2710-22.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Differential, regional, and cellular expression of the stathmin family transcripts in the adult rat brain. Ozon S, etal., J Neurosci Res 1999 Jun 1;56(5):553-64.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Homology between the cDNAs encoding phosphoprotein p19 and SCG10 reveals a novel mammalian gene family preferentially expressed in developing brain. Schubart UK, etal., DNA 1989 Jul-Aug;8(6):389-98.
12. Enhanced expression of uterine stathmin during the process of implantation and decidualization in rats. Tamura K, etal., Endocrinology 2003 Apr;144(4):1464-73.
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PMID:9271428   PMID:9880330   PMID:10369391   PMID:10675326   PMID:10712642   PMID:11839567   PMID:12477932   PMID:12860982   PMID:14769823   PMID:15489334   PMID:15652749   PMID:15659612  
PMID:16110469   PMID:16401721   PMID:16548883   PMID:16982419   PMID:20458337   PMID:20569302   PMID:21625015   PMID:22535533   PMID:24302736   PMID:25122120   PMID:25198505   PMID:25285524  
PMID:26370173   PMID:31933182  



Stmn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,964,308 - 151,970,843 (+)NCBIGRCr8
mRatBN7.25146,680,757 - 146,687,154 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,681,436 - 146,687,154 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,383,560 - 149,389,224 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05151,153,616 - 151,159,276 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05151,139,803 - 151,145,467 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,680,412 - 152,686,807 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,680,407 - 152,686,806 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,466,632 - 156,472,404 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,226,420 - 153,232,084 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15153,236,461 - 153,242,123 (+)NCBI
Celera5145,096,588 - 145,102,252 (+)NCBICelera
Cytogenetic Map5q36NCBI
STMN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38125,884,179 - 25,906,880 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl125,884,181 - 25,906,991 (-)EnsemblGRCh38hg38GRCh38
GRCh37126,210,670 - 26,233,371 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,099,194 - 26,105,955 (-)NCBINCBI36Build 36hg18NCBI36
Build 34125,910,750 - 25,917,510NCBI
Celera124,606,762 - 24,629,447 (-)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,466,602 - 24,489,287 (-)NCBIHuRef
CHM1_1126,323,940 - 26,346,632 (-)NCBICHM1_1
T2T-CHM13v2.0125,721,609 - 25,744,310 (-)NCBIT2T-CHM13v2.0
Stmn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394134,195,631 - 134,201,154 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4134,195,631 - 134,201,154 (+)EnsemblGRCm39 Ensembl
GRCm384134,468,320 - 134,473,843 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,468,320 - 134,473,843 (+)EnsemblGRCm38mm10GRCm38
MGSCv374134,024,235 - 134,029,758 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364133,740,487 - 133,745,915 (+)NCBIMGSCv36mm8
Celera4132,647,807 - 132,653,538 (+)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.76NCBI
Stmn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,388,150 - 5,391,518 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,387,696 - 5,393,337 (-)NCBIChiLan1.0ChiLan1.0
STMN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21200,967,177 - 200,973,463 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11200,065,138 - 200,071,427 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,159,241 - 25,165,535 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,208,731 - 26,230,957 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,208,731 - 26,230,925 (-)Ensemblpanpan1.1panPan2
STMN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,035,462 - 74,043,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,035,457 - 74,043,349 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,610,808 - 70,618,698 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,597,990 - 74,605,869 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,599,514 - 74,605,869 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,422,689 - 71,429,324 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,428,285 - 72,436,168 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,432,116 - 73,440,006 (+)NCBIUU_Cfam_GSD_1.0
Stmn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,645,226 - 44,651,269 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,468,728 - 10,475,594 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,470,006 - 10,475,557 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STMN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,356,412 - 83,362,500 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,356,404 - 83,362,546 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2676,904,244 - 76,934,107 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STMN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,866,719 - 106,873,314 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20106,868,838 - 106,874,403 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660339,543,680 - 9,549,933 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stmn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247649,996,124 - 10,001,197 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247649,996,119 - 10,001,253 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Stmn1
28 total Variants

Predicted Target Of
Summary Value
Count of predictions:79
Count of miRNA genes:55
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000022574
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 42 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat

1 to 10 of 42 rows
RH94569  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2887,337,051 - 87,337,208 (+)MAPPERmRatBN7.2
mRatBN7.25146,686,949 - 146,687,106 (+)MAPPERmRatBN7.2
Rnor_6.0894,041,606 - 94,041,762NCBIRnor6.0
Rnor_6.05152,686,605 - 152,686,761NCBIRnor6.0
Rnor_5.0893,555,446 - 93,555,602UniSTSRnor5.0
Rnor_5.05156,472,203 - 156,472,359UniSTSRnor5.0
Cytogenetic Map8q31UniSTS
Cytogenetic Map5q36UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 26 of 26 rows
RefSeq Transcripts NM_001429881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_017166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X94914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 26 of 26 rows

Ensembl Acc Id: ENSRNOT00000022574   ⟹   ENSRNOP00000022574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5146,683,527 - 146,687,153 (+)Ensembl
Rnor_6.0 Ensembl5152,681,131 - 152,686,806 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076052   ⟹   ENSRNOP00000068006
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5146,681,436 - 146,687,153 (+)Ensembl
Rnor_6.0 Ensembl5152,681,101 - 152,686,806 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5152,681,112 - 152,684,129 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076864   ⟹   ENSRNOP00000068405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5146,681,476 - 146,687,154 (+)Ensembl
Rnor_6.0 Ensembl5152,680,407 - 152,685,974 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105029   ⟹   ENSRNOP00000083571
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5146,682,105 - 146,687,153 (+)Ensembl
RefSeq Acc Id: NM_017166   ⟹   NP_058862
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,965,179 - 151,970,839 (+)NCBI
mRatBN7.25146,681,487 - 146,687,147 (+)NCBI
Rnor_6.05152,681,142 - 152,686,806 (+)NCBI
Rnor_5.05156,466,632 - 156,472,404 (+)NCBI
RGSC_v3.45153,226,420 - 153,232,084 (+)RGD
Celera5145,096,588 - 145,102,252 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239123   ⟹   XP_006239185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,964,308 - 151,970,843 (+)NCBI
mRatBN7.25146,681,341 - 146,687,151 (+)NCBI
Rnor_6.05152,681,028 - 152,686,806 (+)NCBI
Rnor_5.05156,466,632 - 156,472,404 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593202   ⟹   XP_017448691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,964,329 - 151,970,843 (+)NCBI
mRatBN7.25146,680,757 - 146,687,154 (+)NCBI
Rnor_6.05152,680,412 - 152,686,807 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063287250   ⟹   XP_063143320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,965,143 - 151,970,843 (+)NCBI
RefSeq Acc Id: XM_063287251   ⟹   XP_063143321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,966,464 - 151,970,843 (+)NCBI
RefSeq Acc Id: XM_063287252   ⟹   XP_063143322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,965,842 - 151,970,843 (+)NCBI
RefSeq Acc Id: XM_063287253   ⟹   XP_063143323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,964,333 - 151,970,843 (+)NCBI
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: NP_058862   ⟸   NM_017166
- UniProtKB: P13668 (UniProtKB/Swiss-Prot),   A0A8I5ZX99 (UniProtKB/TrEMBL),   A0A8L2QYX2 (UniProtKB/TrEMBL),   A6IT24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239185   ⟸   XM_006239123
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017448691   ⟸   XM_017593202
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000022574   ⟸   ENSRNOT00000022574
Ensembl Acc Id: ENSRNOP00000068405   ⟸   ENSRNOT00000076864
SLD

Name Modeler Protein Id AA Range Protein Structure
AF-P13668-F1-model_v2 AlphaFold P13668 1-149 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694140
Promoter ID:EPDNEW_R4663
Type:initiation region
Name:Stmn1_1
Description:stathmin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05152,681,101 - 152,681,161EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-39568 BioCyc
Ensembl Genes ENSRNOG00000016810 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000022574 ENTREZGENE
  ENSRNOT00000125023 ENTREZGENE
Gene3D-CATH 6.10.280.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6917958 IMAGE-MGC_LOAD
InterPro Stathmin_CS UniProtKB/Swiss-Prot
  Stathmin_fam UniProtKB/Swiss-Prot
  Stathmin_sf UniProtKB/Swiss-Prot
KEGG Report rno:29332 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72884 IMAGE-MGC_LOAD
NCBI Gene Stmn1 ENTREZGENE
PANTHER PTHR10104 UniProtKB/Swiss-Prot
  STATHMIN UniProtKB/Swiss-Prot
Pfam Stathmin UniProtKB/Swiss-Prot
PhenoGen Stmn1 PhenoGen
PIRSF Stathmin UniProtKB/Swiss-Prot
PRINTS STATHMIN UniProtKB/Swiss-Prot
PROSITE STATHMIN_1 UniProtKB/Swiss-Prot
  STATHMIN_2 UniProtKB/Swiss-Prot
  STATHMIN_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016810 RatGTEx
Superfamily-SCOP SSF101494 UniProtKB/Swiss-Prot
UniProt A0A096MK73_RAT UniProtKB/TrEMBL
  A0A8I5ZX99 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QCZ4_RAT UniProtKB/TrEMBL
  A0A8L2QYX2 ENTREZGENE, UniProtKB/TrEMBL
  A6IT24 ENTREZGENE, UniProtKB/TrEMBL
  P13668 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Stmn1  stathmin 1      Symbol and Name status set to approved 625702 APPROVED
2002-06-10 Stmn1  stathmin 1      Symbol and Name updated 70585 PROVISIONAL

Note Type Note Reference
gene_disease may be involved in the development of neuroblastomas and melanomas 61521
gene_disease may be involved in the development of neuroblastomas and melanomas 61528
gene_process functions as an intracellular relay integrating regulatory signals of the cellular environment 61521
gene_process functions as an intracellular relay integrating regulatory signals of the cellular environment 61528