Uts2 (urotensin 2) - Rat Genome Database
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Gene: Uts2 (urotensin 2) Rattus norvegicus
Analyze
Symbol: Uts2
Name: urotensin 2
RGD ID: 3930
Description: Predicted to have hormone activity. Involved in several processes, including negative regulation of secretion; regulation of blood pressure; and regulation of heart rate. Localizes to extracellular space. Used to study hypertension. Biomarker of asthma; cardiomyopathy; endomyocardial fibrosis; myocardial infarction; and pulmonary hypertension. Human ortholog(s) of this gene implicated in gestational diabetes and type 2 diabetes mellitus. Orthologous to human UTS2 (urotensin 2); INTERACTS WITH 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: U-II; Ucn2; UII; urocortin 2; urotensin II; urotensin-2; urotensin-II
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25161,450,846 - 161,456,235 (+)NCBI
Rnor_6.0 Ensembl5168,078,748 - 168,084,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05168,078,748 - 168,084,133 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05171,655,843 - 171,661,228 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45168,143,315 - 168,148,700 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15168,153,502 - 168,158,888 (+)NCBI
Celera5159,703,053 - 159,708,438 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
1. Balat O, etal., Eur J Obstet Gynecol Reprod Biol. 2005 May 1;120(1):33-8.
2. Bousette N, etal., Atherosclerosis. 2004 Sep;176(1):117-23.
3. Cheng DY, etal., Zhonghua Jie He He Hu Xi Za Zhi. 2006 Jun;29(6):381-4.
4. Cheung BM, etal., J Hypertens. 2004 Jul;22(7):1341-4.
5. Coulouarn Y, etal., FEBS Lett 1999 Aug 20;457(1):28-32.
6. Dai HY, etal., J Diabetes Complications. 2008 Mar-Apr;22(2):137-43.
7. Diallo M, etal., Peptides. 2008 May;29(5):813-9. Epub 2007 Nov 6.
8. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. GOA data from the GO Consortium
10. Gruson D, etal., Peptides. 2006 Jun;27(6):1527-31. Epub 2005 Dec 20.
11. Huitron-Resendiz S, etal., J Neurosci. 2005 Jun 8;25(23):5465-74.
12. Johns DG, etal., Naunyn Schmiedebergs Arch Pharmacol. 2004 Oct;370(4):238-50. Epub 2004 Sep 30.
13. Langham RG, etal., Am J Kidney Dis. 2004 Nov;44(5):826-31.
14. Lin Y, etal., Hypertens Res. 2003 Oct;26(10):839-45.
15. Liou JY, etal., Clin Exp Pharmacol Physiol. 2009 Jan 17.
16. Lu Y, etal., Peptides. 2002 Sep;23(9):1631-5.
17. Marco J, etal., Peptides. 2008 May;29(5):852-8. Epub 2007 Sep 4.
18. MGD data from the GO Consortium
19. NCBI rat LocusLink and RefSeq merged data July 26, 2002
20. Pelletier G, etal., Neuroscience. 2002;115(2):525-32.
21. Prosser HC, etal., Peptides. 2006 Dec;27(12):3261-8. Epub 2006 Nov 9.
22. Prosser HC, etal., Peptides. 2008 May;29(5):770-7. Epub 2007 Aug 21.
23. Qi J, etal., Heart Vessels. 2004 Mar;19(2):81-8.
24. RGD automated data pipeline
25. RGD automated import pipeline for gene-chemical interactions
26. Russell FD, etal., Am J Physiol Heart Circ Physiol. 2003 Oct;285(4):H1576-81. Epub 2003 Jun 5.
27. Song W, etal., Kidney Int. 2006 Apr;69(8):1360-8.
28. Spinazzi R, etal., Int J Mol Med. 2006 Dec;18(6):1107-12.
29. Suguro T, etal., Clin Sci (Lond). 2008 Dec;115(11):327-34.
30. Sun DJ, etal., Zhonghua Jie He He Hu Xi Za Zhi. 2006 Mar;29(3):185-8.
31. Suzuki S, etal., Peptides. 2004 Oct;25(10):1803-8.
32. Tan YJ, etal., Zhonghua Fu Chan Ke Za Zhi. 2006 Nov;41(11):732-5.
33. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
34. Tian L, etal., Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1234-42. Epub 2008 Sep 16.
35. Totsune K, etal., Peptides. 2004 Oct;25(10):1809-14.
36. Tsai CS, etal., Atherosclerosis. 2009 Feb 20.
37. Wang HX, etal., Regul Pept. 2009 Apr 10;154(1-3):85-90. doi: 10.1016/j.regpep.2009.01.004. Epub 2009 Jan 27.
38. Watson AM, etal., Neuroscience. 2008 Jul 31;155(1):241-9. Epub 2008 Jul 1.
39. Wu XJ, etal., Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Dec;24(6):656-9.
40. Zhang YG, etal., Acta Pharmacol Sin. 2007 Jan;28(1):36-43.
41. Zhang YG, etal., J Hypertens. 2008 Jun;26(6):1119-26.
42. Zoccali C, etal., Kidney Int. 2006 Apr;69(7):1253-8.
Additional References at PubMed
PMID:15097239   PMID:16171813   PMID:16685423   PMID:16807543   PMID:18318439   PMID:18355946   PMID:18955090   PMID:19463745   PMID:19797237   PMID:19906507   PMID:19930425   PMID:20025629  
PMID:20422157   PMID:21056072   PMID:21186587   PMID:22044114   PMID:22166643   PMID:22244812   PMID:22270542   PMID:23053343   PMID:23403244   PMID:23933501   PMID:24478001   PMID:24481965  
PMID:24521102   PMID:24878476   PMID:25803040   PMID:26323194   PMID:26453012   PMID:27208703   PMID:27448985   PMID:27613164   PMID:28656205   PMID:29257277   PMID:31473519  


Genomics

Comparative Map Data
Uts2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25161,450,846 - 161,456,235 (+)NCBI
Rnor_6.0 Ensembl5168,078,748 - 168,084,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05168,078,748 - 168,084,133 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05171,655,843 - 171,661,228 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45168,143,315 - 168,148,700 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15168,153,502 - 168,158,888 (+)NCBI
Celera5159,703,053 - 159,708,438 (+)NCBICelera
Cytogenetic Map5q36NCBI
UTS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl17,843,083 - 7,853,512 (-)EnsemblGRCh38hg38GRCh38
GRCh3817,846,345 - 7,913,615 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3717,907,672 - 7,913,551 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3617,830,262 - 7,836,159 (-)NCBINCBI36hg18NCBI36
Build 3417,841,940 - 7,847,838NCBI
Celera17,015,352 - 7,021,232 (-)NCBI
Cytogenetic Map1p36.23NCBI
HuRef17,055,968 - 7,061,853 (-)NCBIHuRef
CHM1_117,895,413 - 7,901,298 (-)NCBICHM1_1
Uts2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394151,081,554 - 151,086,267 (+)NCBIGRCm39mm39
GRCm384150,997,097 - 151,001,810 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4150,997,097 - 151,001,810 (+)EnsemblGRCm38mm10GRCm38
MGSCv374150,371,206 - 150,375,919 (+)NCBIGRCm37mm9NCBIm37
MGSCv364149,840,897 - 149,845,610 (+)NCBImm8
Celera4153,272,921 - 153,277,635 (+)NCBICelera
Cytogenetic Map4E2NCBI
Uts2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554865,052,045 - 5,056,610 (+)NCBIChiLan1.0ChiLan1.0
UTS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.117,853,824 - 7,864,688 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl17,854,687 - 7,864,688 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v016,609,104 - 6,616,966 (-)NCBIMhudiblu_PPA_v0panPan3
UTS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1561,503,268 - 61,508,146 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Uts2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366232,339,259 - 2,345,717 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UTS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl668,552,887 - 68,559,687 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1668,552,889 - 68,560,827 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
UTS2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120123,903,137 - 123,910,180 (+)NCBI


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)561612600168109659Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)584963058173504662Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5128687766173687766Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5131077716173707219Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132551937173707219Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133943857173707219Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133943857173707219Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5134197905173707219Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5134712342173707219Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5134712342173707219Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5136354114173707219Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136640731173707219Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138154677172402610Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5142307322173707219Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5142309061173707219Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149029982173687766Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5157319671171194163Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5157319671173707219Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5161084664173707219Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:21
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000024798
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 2 5 6 2
Below cutoff 1 5 6 1 5 7 15 1 9 2 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024798   ⟹   ENSRNOP00000024798
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5168,078,748 - 168,084,145 (+)Ensembl
RefSeq Acc Id: NM_019160   ⟹   NP_062033
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25161,450,846 - 161,456,235 (+)NCBI
Rnor_6.05168,078,748 - 168,084,133 (+)NCBI
Rnor_5.05171,655,843 - 171,661,228 (+)NCBI
RGSC_v3.45168,143,315 - 168,148,700 (+)RGD
Celera5159,703,053 - 159,708,438 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_062033 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD55766 (Get FASTA)   NCBI Sequence Viewer  
  EDL81198 (Get FASTA)   NCBI Sequence Viewer  
  Q9QZQ4 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_062033   ⟸   NM_019160
- Peptide Label: precursor
- UniProtKB: Q9QZQ4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024798   ⟸   ENSRNOT00000024798

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3930 AgrOrtholog
Ensembl Genes ENSRNOG00000018393 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000024798 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024798 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Urotensin_II UniProtKB/Swiss-Prot
KEGG Report rno:29180 UniProtKB/Swiss-Prot
NCBI Gene 29180 ENTREZGENE
Pfam Urotensin_II UniProtKB/Swiss-Prot
PhenoGen Uts2 PhenoGen
PROSITE UROTENSIN_II UniProtKB/Swiss-Prot
TIGR TC201608
UniProt Q9QZQ4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Uts2  urotensin 2      Name updated 70584 APPROVED
2001-12-10 Uts2  urotensin 2      Symbol and Name updated to reflect Human and Mouse nomenclature 69665 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mainly expressed in motoneurons of the brainstem and spinal cord 70048