Pla2g2c (phospholipase A2, group IIC) - Rat Genome Database

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Gene: Pla2g2c (phospholipase A2, group IIC) Rattus norvegicus
Analyze
Symbol: Pla2g2c
Name: phospholipase A2, group IIC
RGD ID: 3340
Description: Enables calcium-dependent phospholipase A2 activity. Predicted to be involved in phosphatidylcholine metabolic process and phosphatidylglycerol metabolic process. Predicted to be located in extracellular region and membrane. Orthologous to human PLA2G2C (phospholipase A2 group IIC); PARTICIPATES IN alpha-linolenic acid metabolic pathway; arachidonic acid metabolic pathway; ether lipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 14 kDa phospholipase A2; GIIC sPLA2; group IIC secretory phospholipase A2; phosphatidylcholine 2-acylhydrolase 2C; phosphatidylcholine 2-acylhydrolase GIIC; phospholipase A2 group IIC; phospholipase A2, group 2C; PLA2-8; sPLA2-IIC
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,241,142 - 156,262,368 (+)NCBIGRCr8
mRatBN7.25150,959,365 - 150,981,388 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5150,959,182 - 150,981,377 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5153,657,591 - 153,676,975 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,431,891 - 155,451,281 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,413,404 - 155,432,759 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,163,672 - 157,187,654 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,165,341 - 157,187,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05160,903,738 - 160,929,464 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45157,536,546 - 157,555,895 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15157,300,874 - 157,568,245 (+)NCBI
Celera5149,347,976 - 149,367,111 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pla2g2cRat3-hydroxy-3-methylglutaryl-CoA lyase deficiency  ISOPLA2G2C (Homo sapiens)8554872ClinVar Annotator: match by term: Deficiency of hydroxymethylglutaryl-CoA lyaseClinVarPMID:28492532
Pla2g2cRatchromosome 1p36 deletion syndrome  ISOPLA2G2C (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 1p36 deletion syndromeClinVar 
Pla2g2cRatcongenital disorder of glycosylation Ir  ISOPLA2G2C (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital disorder of glycosylation type IrClinVarPMID:28492532
Pla2g2cRathyperprolinemia type 2  ISOPLA2G2C (Homo sapiens)8554872ClinVar Annotator: match by term: Hyperprolinemia type 2ClinVarPMID:28492532
Pla2g2cRatParkinson's disease 6  ISOPLA2G2C (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive early-onset Parkinson disease 6ClinVarPMID:28492532

1 to 20 of 35 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pla2g2cRat1,2-dimethylhydrazine decreases expressionISOPla2g2c (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of PLA2G2C mRNACTDPMID:22206623
Pla2g2cRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPla2g2c (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of PLA2G2C mRNACTDPMID:23994337
Pla2g2cRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PLA2G2C mRNACTDPMID:32109520
Pla2g2cRat2,3,7,8-Tetrachlorodibenzofuran increases expressionEXP 64804642 more ...CTDPMID:32109520
Pla2g2cRat3,3',4,4',5-pentachlorobiphenyl increases expressionISOPla2g2c (Mus musculus)64804643 more ...CTDPMID:23994337
Pla2g2cRat3H-1,2-dithiole-3-thione increases expressionEXP 64804641 and 2-dithiol-3-thione results in increased expression of PLA2G2C mRNACTDPMID:19162173
Pla2g2cRataflatoxin B1 increases methylationISOPLA2G2C (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of PLA2G2C geneCTDPMID:27153756
Pla2g2cRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of PLA2G2C mRNACTDPMID:16483693
Pla2g2cRatarsane increases methylationISOPLA2G2C (Homo sapiens)6480464Arsenic results in increased methylation of PLA2G2C geneCTDPMID:25325195
Pla2g2cRatarsenic atom increases methylationISOPLA2G2C (Homo sapiens)6480464Arsenic results in increased methylation of PLA2G2C geneCTDPMID:25325195
Pla2g2cRatAzoxymethane multiple interactionsISOPla2g2c (Mus musculus)6480464[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PLA2G2C mRNACTDPMID:29950665
Pla2g2cRatbenzo[a]pyrene affects methylationISOPLA2G2C (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of PLA2G2C promoterCTDPMID:27901495
Pla2g2cRatbeta-naphthoflavone increases expressionISOPla2g2c (Mus musculus)6480464beta-Naphthoflavone results in increased expression of PLA2G2C mRNACTDPMID:23994337
Pla2g2cRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of PLA2G2C mRNACTDPMID:25181051 and PMID:34947998
Pla2g2cRatbisphenol A decreases methylationISOPla2g2c (Mus musculus)6480464bisphenol A results in decreased methylation of PLA2G2C promoterCTDPMID:27312807
Pla2g2cRatcadmium dichloride decreases expressionEXP 6480464Cadmium Chloride results in decreased expression of PLA2G2C mRNACTDPMID:33453195
Pla2g2cRatCuprizon increases expressionEXP 6480464Cuprizone results in increased expression of PLA2G2C mRNACTDPMID:26577399
Pla2g2cRatdecabromodiphenyl ether decreases expressionEXP 6480464decabromobiphenyl ether results in decreased expression of PLA2G2C mRNACTDPMID:23640034
Pla2g2cRatdextran sulfate multiple interactionsISOPla2g2c (Mus musculus)6480464[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PLA2G2C mRNACTDPMID:29950665
Pla2g2cRatdichlorine multiple interactionsEXP 6480464[Ozone co-treated with Chlorine] results in increased expression of PLA2G2C mRNACTDPMID:18636392

1 to 20 of 35 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pla2g2cRatarachidonate secretion involved_inIEAInterPro:IPR016090 and InterPro:IPR0364441600115GO_REF:0000002InterProGO_REF:0000002
Pla2g2cRatlipid catabolic process involved_inIEAInterPro:IPR0012111600115GO_REF:0000002InterProGO_REF:0000002
Pla2g2cRatlipid catabolic process involved_inIEAUniProtKB-KW:KW-04421600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g2cRatlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g2cRatphosphatidylcholine metabolic process involved_inIBAMGI:1341796 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pla2g2cRatphosphatidylglycerol metabolic process involved_inIBAMGI:1341796 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pla2g2cRatphospholipid metabolic process involved_inIEAInterPro:IPR016090 and InterPro:IPR0364441600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pla2g2cRatextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Pla2g2cRatextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g2cRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pla2g2cRatcalcium ion binding enablesIEAInterPro:IPR0012111600115GO_REF:0000002InterProGO_REF:0000002
Pla2g2cRatcalcium ion binding enablesIBAMGI:1313269 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pla2g2cRatcalcium-dependent phospholipase A2 activity  IDA 69933 RGD 
Pla2g2cRatcalcium-dependent phospholipase A2 activity enablesIBAMGI:1341796 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pla2g2cRathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g2cRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g2cRatphospholipase A2 activity enablesIEAARBA:ARBA000285441600115GO_REF:0000117UniProtGO_REF:0000117
Pla2g2cRatphospholipase A2 activity enablesIEARHEA:158011600115GO_REF:0000116RHEAGO_REF:0000116
Pla2g2cRatphospholipase A2 activity enablesIEAInterPro:IPR001211 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Pla2g2cRatphospholipase A2 activity enablesIEAEC:3.1.1.41600115GO_REF:0000003UniProtGO_REF:0000003
Pla2g2cRatphospholipid binding enablesIBAPANTHER:PTN000919171 and UniProtKB:P145551600115GO_REF:0000033GO_CentralGO_REF:0000033
Pla2g2cRatsignaling receptor binding enablesIBAMGI:101842 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 12 of 12 rows

Imported Annotations - KEGG (archival)

1 to 13 of 13 rows
1 to 13 of 13 rows

1 to 9 of 9 rows
#
Reference Title
Reference Citation
1. Cloning and characterization of novel rat and mouse low molecular weight Ca(2+)-dependent phospholipase A2s containing 16 cysteines. Chen J, etal., J Biol Chem 1994 Sep 16;269(37):23018-24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
1 to 9 of 9 rows
PMID:12477932  



Pla2g2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,241,142 - 156,262,368 (+)NCBIGRCr8
mRatBN7.25150,959,365 - 150,981,388 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5150,959,182 - 150,981,377 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5153,657,591 - 153,676,975 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,431,891 - 155,451,281 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,413,404 - 155,432,759 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,163,672 - 157,187,654 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,165,341 - 157,187,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05160,903,738 - 160,929,464 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45157,536,546 - 157,555,895 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15157,300,874 - 157,568,245 (+)NCBI
Celera5149,347,976 - 149,367,111 (+)NCBICelera
Cytogenetic Map5q36NCBI
PLA2G2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38120,163,055 - 20,186,518 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl120,161,253 - 20,186,518 (-)EnsemblGRCh38hg38GRCh38
GRCh37120,489,548 - 20,513,011 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36120,363,071 - 20,374,274 (-)NCBINCBI36Build 36hg18NCBI36
Celera118,813,602 - 18,824,805 (-)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef118,736,223 - 18,747,426 (-)NCBIHuRef
CHM1_1120,600,161 - 20,611,364 (-)NCBICHM1_1
T2T-CHM13v2.0119,986,700 - 20,010,162 (-)NCBIT2T-CHM13v2.0
Pla2g2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394138,452,636 - 138,471,886 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4138,452,103 - 138,473,443 (+)EnsemblGRCm39 Ensembl
GRCm384138,725,325 - 138,744,575 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4138,724,792 - 138,746,132 (+)EnsemblGRCm38mm10GRCm38
MGSCv374138,281,240 - 138,300,490 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364137,997,817 - 138,016,649 (+)NCBIMGSCv36mm8
Celera4140,507,993 - 140,527,237 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.54NCBI
Pla2g2c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955452770,952 - 783,375 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955452771,031 - 783,323 (-)NCBIChiLan1.0ChiLan1.0
PLA2G2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21206,931,634 - 206,955,707 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,048,484 - 206,072,513 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0119,118,341 - 19,142,668 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1120,162,076 - 20,173,928 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl120,161,553 - 20,176,092 (-)Ensemblpanpan1.1panPan2
PLA2G2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1278,609,852 - 78,700,940 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,193,206 - 75,214,536 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,245,924 - 79,267,303 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,183,293 - 79,267,303 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,065,084 - 76,086,418 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,071,825 - 77,093,190 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,142,515 - 78,163,886 (+)NCBIUU_Cfam_GSD_1.0
LOC101976106
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505840,382,221 - 40,391,693 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364746,207,021 - 6,212,347 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA2G2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1678,433,168 - 78,446,562 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2672,624,176 - 72,644,067 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLA2G2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120112,365,898 - 112,389,268 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20112,375,528 - 112,389,008 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660333,795,009 - 3,887,678 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pla2g2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247645,257,955 - 5,269,744 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pla2g2c
159 total Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
5 157547442 157547443 C G snv SR/JrHsd (MCW), FHH/EurMcwi (MCW) View more Information


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
5 160918763 160918764 C G snv SR/JrHsd (MCW), FHH/EurMcwi (MCW) View more Information

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:85
Interacting mature miRNAs:95
Transcripts:ENSRNOT00000043029
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 38 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat

1 to 10 of 38 rows
RH137900  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25150,981,228 - 150,981,363 (+)MAPPERmRatBN7.2
Rnor_6.05157,187,495 - 157,187,629NCBIRnor6.0
Rnor_5.05160,929,305 - 160,929,439UniSTSRnor5.0
RGSC_v3.45157,558,047 - 157,558,181UniSTSRGSC3.4
Celera5149,369,263 - 149,369,397UniSTS
RH 3.4 Map51033.0UniSTS
Cytogenetic Map5q36UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 106 38 44 13 17 13 6 155 82 93 43 60 31



Ensembl Acc Id: ENSRNOT00000043029   ⟹   ENSRNOP00000039825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5157,165,888 - 157,185,343 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087072   ⟹   ENSRNOP00000072615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5150,959,182 - 150,981,377 (+)Ensembl
Rnor_6.0 Ensembl5157,165,341 - 157,187,643 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112153   ⟹   ENSRNOP00000097954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5150,968,433 - 150,981,377 (+)Ensembl
RefSeq Acc Id: NM_019202   ⟹   NP_062075
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,242,998 - 156,262,368 (+)NCBI
mRatBN7.25150,959,729 - 150,979,077 (+)NCBI
Rnor_6.05157,165,888 - 157,185,343 (+)NCBI
Rnor_5.05160,903,738 - 160,929,464 (+)NCBI
RGSC_v3.45157,536,546 - 157,555,895 (+)RGD
Celera5149,347,976 - 149,367,111 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239142   ⟹   XP_006239204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,242,958 - 156,262,363 (+)NCBI
mRatBN7.25150,959,723 - 150,981,388 (+)NCBI
Rnor_6.05157,165,832 - 157,187,654 (+)NCBI
Rnor_5.05160,903,738 - 160,929,464 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239143   ⟹   XP_006239205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,241,142 - 156,262,363 (+)NCBI
mRatBN7.25150,959,365 - 150,981,388 (+)NCBI
Rnor_6.05157,165,713 - 157,187,654 (+)NCBI
Rnor_5.05160,903,738 - 160,929,464 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109368   ⟹   XP_038965296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,242,984 - 156,262,363 (+)NCBI
mRatBN7.25150,959,723 - 150,981,388 (+)NCBI
RefSeq Acc Id: XM_039109369   ⟹   XP_038965297
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,242,954 - 156,262,363 (+)NCBI
mRatBN7.25150,959,685 - 150,981,388 (+)NCBI
RefSeq Acc Id: NP_062075   ⟸   NM_019202
- Peptide Label: precursor
- UniProtKB: P39878 (UniProtKB/Swiss-Prot),   Q4V8L7 (UniProtKB/TrEMBL),   A0A0G2K3F5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239205   ⟸   XM_006239143
- Peptide Label: isoform X1
- UniProtKB: P39878 (UniProtKB/Swiss-Prot),   Q4V8L7 (UniProtKB/TrEMBL),   A0A0G2K3F5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239204   ⟸   XM_006239142
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000039825   ⟸   ENSRNOT00000043029
Ensembl Acc Id: ENSRNOP00000072615   ⟸   ENSRNOT00000087072
Phospholipase A2

Name Modeler Protein Id AA Range Protein Structure
AF-P39878-F1-model_v2 AlphaFold P39878 1-150 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694191
Promoter ID:EPDNEW_R4716
Type:single initiation site
Name:Pla2g2c_1
Description:phospholipase A2, group IIC
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05157,165,869 - 157,165,929EPDNEW


1 to 28 of 28 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-39443 BioCyc
Ensembl Genes ENSRNOG00000016647 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000087072 ENTREZGENE
Gene3D-CATH 1.20.90.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7456563 IMAGE-MGC_LOAD
InterPro PLipase_A2 UniProtKB/Swiss-Prot
  PLipase_A2_Asp_AS UniProtKB/Swiss-Prot
  PLipase_A2_dom UniProtKB/Swiss-Prot
  PLipase_A2_dom_sf UniProtKB/Swiss-Prot
  PLipase_A2_His_AS UniProtKB/Swiss-Prot
KEGG Report rno:29387 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114328 IMAGE-MGC_LOAD
NCBI Gene 29387 ENTREZGENE
PANTHER INACTIVE GROUP IIC SECRETORY PHOSPHOLIPASE A2-RELATED UniProtKB/Swiss-Prot
  PTHR11716 UniProtKB/Swiss-Prot
Pfam Phospholip_A2_1 UniProtKB/Swiss-Prot
PhenoGen Pla2g2c PhenoGen
PRINTS PHPHLIPASEA2 UniProtKB/Swiss-Prot
PROSITE PA2_ASP UniProtKB/Swiss-Prot
  PA2_HIS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016647 RatGTEx
SMART PA2c UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48619 UniProtKB/Swiss-Prot
TIGR TC209648
UniProt A0A0G2K3F5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ASV9_RAT UniProtKB/TrEMBL
  P39878 ENTREZGENE, UniProtKB/Swiss-Prot
  Q4V8L7 ENTREZGENE, UniProtKB/TrEMBL
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-05-15 Pla2g2c  phospholipase A2, group IIC  Pla2g2c  phospholipase A2, group 2C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Pla2g2c  phospholipase A2, group 2C      Symbol and Name status set to approved 1299863 APPROVED
2002-06-10 Pla2g2c  phospholipase A2, group 2C      Name updated 70585 PROVISIONAL