Acot7 (acyl-CoA thioesterase 7) - Rat Genome Database

Name: Acot7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Acot7 (acyl-CoA thioesterase 7) Rattus norvegicus

Analyze

Symbol:

Acot7

Name:

acyl-CoA thioesterase 7

RGD ID:

628856

Description:

Exhibits acyl-CoA hydrolase activity. Predicted to be involved in fatty acid metabolic process and purine nucleoside bisphosphate metabolic process. Localizes to cytosol. Orthologous to human ACOT7 (acyl-CoA thioesterase 7); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

ACH1; ACT; Bach; brain acyl-CoA hydrolase; CTE-II; CTE-IIa; CTE-IIb; cytosolic acyl coenzyme A thioester hydrolase; LACH1; long chain acyl-CoA thioester hydrolase; MGC105261; MTE-II; Rbach

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACOT7 (acyl-CoA thioesterase 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Acot7 (acyl-CoA thioesterase 7)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Acot7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACOT7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACOT7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Acot7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACOT7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	ACOT7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Acot7 (acyl-CoA thioesterase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ACOT7 (acyl-CoA thioesterase 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Acot7 (acyl-CoA thioesterase 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	acot7 (acyl-CoA thioesterase 7)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	162,686,562 - 162,779,309 (+)	NCBI
Rnor_6.0 Ensembl	5	169,357,517 - 169,450,219 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	5	169,357,582 - 169,450,215 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	169,409,306 - 169,501,907 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	169,419,590 - 169,512,094 (+)	NCBI
Celera	5	160,918,240 - 161,010,763 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP,ISO)

2,6-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

5-fluorouracil (ISO)

6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bortezomib (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

clofibric acid (EXP)

cobalt dichloride (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (EXP,ISO)

dichlorine (EXP)

endosulfan (EXP)

Enterolactone (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

finasteride (EXP)

folic acid (ISO)

GW 4064 (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

lead diacetate (ISO)

leflunomide (EXP)

N-nitrosodiethylamine (EXP)

nefazodone (EXP)

nickel atom (ISO)

nimesulide (EXP)

oleic acid (ISO)

ozone (EXP)

paracetamol (ISO)

paraquat (EXP)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

pirinixic acid (EXP,ISO)

progesterone (ISO)

quinoline (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

Tesaglitazar (EXP)

thapsigargin (ISO)

theophylline (ISO)

trichloroethene (ISO)

trimellitic anhydride (ISO)

troglitazone (EXP)

tunicamycin (ISO)

valproic acid (ISO)

zinc atom (EXP)

zinc(0) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acyl-CoA metabolic process (IBA)

coenzyme A biosynthetic process (ISO)

fatty acid catabolic process (ISO)

fatty acid metabolic process (IBA,IEA)

long-chain fatty-acyl-CoA catabolic process (ISO)

medium-chain fatty acid biosynthetic process (ISO)

medium-chain fatty-acyl-CoA catabolic process (ISO)

palmitic acid biosynthetic process (IBA,ISO)

Cellular Component

cell body (ISO)

cytoplasm (ISO)

cytosol (IBA,IDA,ISO)

neuron projection (ISO)

nucleoplasm (IBA,ISO)

Molecular Function

acyl-CoA hydrolase activity (IBA,IDA)

carboxylic ester hydrolase activity (IEA)

fatty-acyl-CoA binding (ISO)

identical protein binding (ISO)

long-chain fatty acyl-CoA binding (IBA,ISO)

myristoyl-CoA hydrolase activity (IEA)

palmitoyl-CoA hydrolase activity (IBA,ISO)

protein binding (ISO)

protein homodimerization activity (ISO)

thiolester hydrolase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

unsaturated fatty acid biosynthetic pathway (IEA)

References

References - curated


1.	Broustas CG, etal., J Biol Chem 1996 May 3;271(18):10470-6.
2.	Engberg ST, etal., Biochem J 1997 Apr 15;323 ( Pt 2):525-31.
3.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	MGD data from the GO Consortium
5.	Pipeline to import KEGG annotations from KEGG into RGD
6.	RGD automated import pipeline for gene-chemical interactions
7.	Yamada J, etal., Biochem Biophys Res Commun 1997 Mar 6;232(1):198-203.

Additional References at PubMed

PMID:7906114	PMID:10578051	PMID:11755680	PMID:11834298	PMID:12435388	PMID:12477932	PMID:15489334	PMID:16103133	PMID:17563367	PMID:18324622	PMID:19056867

Genomics

Comparative Map Data

Acot7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	162,686,562 - 162,779,309 (+)	NCBI
Rnor_6.0 Ensembl	5	169,357,517 - 169,450,219 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	5	169,357,582 - 169,450,215 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	169,409,306 - 169,501,907 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	169,419,590 - 169,512,094 (+)	NCBI
Celera	5	160,918,240 - 161,010,763 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

ACOT7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	6,264,269 - 6,393,767 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p13 Ensembl	1	6,264,269 - 6,394,391 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	6,264,272 - 6,393,767 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	6,324,332 - 6,453,827 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	6,246,919 - 6,376,413 (-)	NCBI	NCBI36		hg18	NCBI36
Celera	1	5,438,842 - 5,568,337 (-)	NCBI
Cytogenetic Map	1	p36.31	NCBI
HuRef	1	5,472,303 - 5,601,612 (-)	NCBI		HuRef
CHM1_1	1	6,312,939 - 6,442,400 (-)	NCBI		CHM1_1

Acot7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	152,258,872 - 152,356,312 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	4	152,262,591 - 152,356,312 (+)	Ensembl
GRCm38	4	152,178,100 - 152,271,855 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	152,178,134 - 152,271,855 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	151,552,209 - 151,645,964 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	4	151,021,934 - 151,115,647 (+)	NCBI			mm8
Celera	4	154,464,405 - 154,558,717 (+)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI

Acot7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	6,188,102 - 6,259,110 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955486	6,188,102 - 6,258,230 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACOT7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	6,287,177 - 6,402,767 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	1	5,030,488 - 5,154,800 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

ACOT7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	5	60,153,616 - 60,239,239 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	5	60,153,616 - 60,239,254 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Acot7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936623	1,112,021 - 1,191,190 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACOT7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	67,152,428 - 67,254,103 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	67,152,428 - 67,254,097 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	62,103,745 - 62,205,894 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACOT7
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	125,345,636 - 125,474,650 (+)	NCBI
ChlSab1.1 Ensembl	20	125,345,670 - 125,474,690 (+)	Ensembl

Acot7
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624818	5,048,410 - 5,142,135 (+)	NCBI

Position Markers

RH129039

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	5	169,449,965 - 169,450,181	NCBI	Rnor6.0
Rnor_5.0	5	173,003,304 - 173,003,520	UniSTS	Rnor5.0
RGSC_v3.4	5	169,501,657 - 169,501,873	UniSTS	RGSC3.4
Celera	5	161,010,513 - 161,010,729	UniSTS
RH 3.4 Map	5	1139.3	UniSTS
Cytogenetic Map	5	q36	UniSTS

AW557066

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	5	169,449,821 - 169,449,971	NCBI	Rnor6.0
Rnor_5.0	5	173,003,160 - 173,003,310	UniSTS	Rnor5.0
RGSC_v3.4	5	169,501,513 - 169,501,663	UniSTS	RGSC3.4
Celera	5	161,010,369 - 161,010,519	UniSTS
Cytogenetic Map	5	q36	UniSTS

D1S2335E

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	5	169,439,820 - 169,439,936	NCBI	Rnor6.0
Rnor_5.0	5	172,993,159 - 172,993,275	UniSTS	Rnor5.0
RGSC_v3.4	5	169,491,512 - 169,491,628	UniSTS	RGSC3.4
Celera	5	161,000,368 - 161,000,484	UniSTS
Cytogenetic Map	5	q36	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	142309061	173707219	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132551937	173707219	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	149029982	173687766	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	142307322	173707219	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	136354114	173707219	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	157319671	173707219	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138154677	172402610	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	84963058	173504662	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	128687766	173687766	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133943857	173707219	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133943857	173707219	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	134197905	173707219	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	157319671	171194163	Rat
1549904	Neuinf1	Neuroinflammation QTL 1	3	0	nervous system integrity trait (VT:0010566)	blood T lymphocyte count (CMO:0000110)	5	161084664	173707219	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136640731	173707219	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	134712342	173707219	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	134712342	173707219	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	131077716	173707219	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	346
Count of miRNA genes:	126
Interacting mature miRNAs:	142
Transcripts:	ENSRNOT00000000079, ENSRNOT00000014213
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	36	36	27	15	27		3	74	29	36	9
Low		7	21	14	4	14	8	8		6	5	2	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001146061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_013214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005504373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC135674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK469690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D88891	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DY317682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U49694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y09332	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000000079 ⟹ ENSRNOP00000000079

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	169,357,517 - 169,450,219 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000014213 ⟹ ENSRNOP00000014213

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	169,364,306 - 169,450,214 (+)	Ensembl

RefSeq Acc Id:

NM_001146061 ⟹ NP_001139533

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,693,400 - 162,779,309 (+)	NCBI
Rnor_6.0	5	169,364,306 - 169,450,215 (+)	NCBI
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI
RGSC_v3.4	5	169,409,306 - 169,501,907 (+)	RGD
Celera	5	160,924,964 - 161,010,763 (+)	NCBI

Sequence:

show sequence

CAGCTGCTAAGCTTGGTGCTGTGAGGGAAGAGAAAGGCTTTGTCCCATTCCTAGAATGAAGCTG
CTTGCTAGGACTCTGTACCTCTGGGAGGTGGGGAGACAGGTAGCCTCTTGGAGCCTGACGTCTG
GCCAGGAGTGTTTGGTGCTCAGGGAAACATGGTGGGCTTCGATGAGGGCTGTCAGAACCAGAGC
AGTTCATCACAAGCCTGGACATTGCATCGCCATGGGAAGGATCATGCGTCCGGATGATGCCAAC
GTGGCCGGCAATGTTCACGGAGGGACCATTCTAAAGATGATCGAGGAGGCTGGGGTCATCATCA
GCACCCGGCACTGTAACAGCCAGAATGGGGAGCGCTGTGTGGCTGCCCTGGCCCGGGTGGAGCG
CACTGACTTCCTGTCGCCCATGTGCATCGGTGAGGTGGCTCACGTCAGCGCAGAGATCACCTAT
ACTTCCAAGCACTCTGTGGAGGTCCAGGTCCACGTGTTGTCGGAGAACATCCTCACAGGTACCA
AAAAGCTGACCAATAAGGCCACCTTGTGGTATGTGCCCCTGTCATTGAAGAATGTGGACAAGGT
CCTTGAGGTGCCTCCTATTGTGTATTTACGGCAGGAACAGGAGGAGGAGGGTCGGAAACGCTAT
GAAGCCCAGAAGCTAGAACGCATGGAGACCAAGTGGAGGAACGGAGACATTGTCCAGCCCATCC
TGAACCCAGAGCCGAACACAGTGAGCTACAGCCAGTCCAGCCTGATCCACCTGGTGGGGCCCTC
AGACTGCACTCTTCATGGCTTCGTGCACGGAGGTGTCACCATGAAGCTCATGGATGAGGTGGCC
GGGATTGTGGCTGCGCGCCACTGCAAGACCAATATAGTGACTGCCTCTGTGGATGCTATTAATT
TCCATGACAAGATCCGGAAAGGCTGTGTCATCACCATCTCTGGACGCATGACCTTCACAAGCAA
TAAGTCTATGGAAATTGAGGTCCTGGTGGACGCTGACCCTGTGGTGGACAACTCACAGAAGCGC
TACCGGGCTGCCAGTGCCTTCTTCACCTACGTGTCCCTGAATCAGGAGGGCAAGCCGCTGCCTG
TGCCTCAGCTTGTGCCGGAGACGGAGGACGAGAAGAAGCGTTTTGAAGAAGGCAAAGGCCGCTA
TCTGCAGATGAAGGCGAAGCGACAGGGCCATACAGAGCCTCAGCCCTAGATGTCTTCCTCCCTC
CCATCCTGTCCCGTCCTGGGTCAGCACAGTTGTGGCAGTAGTCCTGTGTGCAGTCACTTAGAAG
TCGCCCCCTTGGCCAAACCCCGATTTCCTTTGAGAGCTGGTGTTGTGAAGTACCGTGTGGCAGT
GTTACCTGTGGCCTGTTCCCAAAACCTGTGCACCAAAGCTTTATTTATATCCCTCCAGTCCCTG
CTCCCATGTTGTCCCAAAGGCCATCGTGGACACCAGAGCACACTGACTGGCCTGGAGAAGCCAG
CACCACTAATAAAGCTGCTGTCTGGCTGGAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_013214 ⟹ NP_037346

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,686,676 - 162,779,309 (+)	NCBI
Rnor_6.0	5	169,357,582 - 169,450,215 (+)	NCBI
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI
RGSC_v3.4	5	169,409,306 - 169,501,907 (+)	RGD
Celera	5	160,918,240 - 161,010,763 (+)	RGD

Sequence:

show sequence

CTCCTCTTTTATGGCGCCTCCCAGGCTCATTCATTCGGCGCCGGGCCTGCTGGACACCTGTTCT
CAGATCCCGCCGCCGCCGTCGCCGCCGCCGCCCGCCGTCGCAGCCAAGATGTCCGGTCCCACCA
CCGACACGCCGGCCGCCATCCAGATCTGCCGGATCATGCGTCCGGATGATGCCAACGTGGCCGG
CAATGTTCACGGAGGGACCATTCTAAAGATGATCGAGGAGGCTGGGGTCATCATCAGCACCCGG
CACTGTAACAGCCAGAATGGGGAGCGCTGTGTGGCTGCCCTGGCCCGGGTGGAGCGCACTGACT
TCCTGTCGCCCATGTGCATCGGTGAGGTGGCTCACGTCAGCGCAGAGATCACCTATACTTCCAA
GCACTCTGTGGAGGTCCAGGTCCACGTGTTGTCGGAGAACATCCTCACAGGTACCAAAAAGCTG
ACCAATAAGGCCACCTTGTGGTATGTGCCCCTGTCATTGAAGAATGTGGACAAGGTCCTTGAGG
TGCCTCCTATTGTGTATTTACGGCAGGAACAGGAGGAGGAGGGTCGGAAACGCTATGAAGCCCA
GAAGCTAGAACGCATGGAGACCAAGTGGAGGAACGGAGACATTGTCCAGCCCATCCTGAACCCA
GAGCCGAACACAGTGAGCTACAGCCAGTCCAGCCTGATCCACCTGGTGGGGCCCTCAGACTGCA
CTCTTCATGGCTTCGTGCACGGAGGTGTCACCATGAAGCTCATGGATGAGGTGGCCGGGATTGT
GGCTGCGCGCCACTGCAAGACCAATATAGTGACTGCCTCTGTGGATGCTATTAATTTCCATGAC
AAGATCCGGAAAGGCTGTGTCATCACCATCTCTGGACGCATGACCTTCACAAGCAATAAGTCTA
TGGAAATTGAGGTCCTGGTGGACGCTGACCCTGTGGTGGACAACTCACAGAAGCGCTACCGGGC
TGCCAGTGCCTTCTTCACCTACGTGTCCCTGAATCAGGAGGGCAAGCCGCTGCCTGTGCCTCAG
CTTGTGCCGGAGACGGAGGACGAGAAGAAGCGTTTTGAAGAAGGCAAAGGCCGCTATCTGCAGA
TGAAGGCGAAGCGACAGGGCCATACAGAGCCTCAGCCCTAGATGTCTTCCTCCCTCCCATCCTG
TCCCGTCCTGGGTCAGCACAGTTGTGGCAGTAGTCCTGTGTGCAGTCACTTAGAAGTCGCCCCC
TTGGCCAAACCCCGATTTCCTTTGAGAGCTGGTGTTGTGAAGTACCGTGTGGCAGTGTTACCTG
TGGCCTGTTCCCAAAACCTGTGCACCAAAGCTTTATTTATATCCCTCCAGTCCCTGCTCCCATG
TTGTCCCAAAGGCCATCGTGGACACCAGAGCACACTGACTGGCCTGGAGAAGCCAGCACCACTA
ATAAAGCTGCTGTCTGGCTGGAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006239448 ⟹ XP_006239510

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,707,899 - 162,779,309 (+)	NCBI
Rnor_6.0	5	169,378,805 - 169,450,215 (+)	NCBI
Rnor_5.0	5	172,912,096 - 173,003,554 (+)	NCBI

Sequence:

show sequence

TGAGTTAGGAACTGGGCGGAGCTGGGGCTTCCCTGAGTGGGAGAAGTGTTGAGACCTGCTTTGG
TACCTGAGTGGTCAGATCTGTGGTGGTCTGACCTTGGGTGGTCTGACCTTTGGCTTGGGGTCCT
GGGATGCTTTGGTGTCCTTTCCTCTGACTTGAAGGATCATGCGTCCGGATGATGCCAACGTGGC
CGGCAATGTTCACGGAGGGACCATTCTAAAGATGATCGAGGAGGCTGGGGTCATCATCAGCACC
CGGCACTGTAACAGCCAGAATGGGGAGCGCTGTGTGGCTGCCCTGGCCCGGGTGGAGCGCACTG
ACTTCCTGTCGCCCATGTGCATCGGTGAGGTGGCTCACGTCAGCGCAGAGATCACCTATACTTC
CAAGCACTCTGTGGAGGTCCAGGTCCACGTGTTGTCGGAGAACATCCTCACAGGTACCAAAAAG
CTGACCAATAAGGCCACCTTGTGGTATGTGCCCCTGTCATTGAAGAATGTGGACAAGGTCCTTG
AGGTGCCTCCTATTGTGTATTTACGGCAGGAACAGGAGGAGGAGGGTCGGAAACGCTATGAAGC
CCAGAAGCTAGAACGCATGGAGACCAAGTGGAGGAACGGAGACATTGTCCAGCCCATCCTGAAC
CCAGAGCCGAACACAGTGAGCTACAGCCAGTCCAGCCTGATCCACCTGGTGGGGCCCTCAGACT
GCACTCTTCATGGCTTCGTGCACGGAGGTGTCACCATGAAGCTCATGGATGAGGTGGCCGGGAT
TGTGGCTGCGCGCCACTGCAAGACCAATATAGTGACTGCCTCTGTGGATGCTATTAATTTCCAT
GACAAGATCCGGAAAGGCTGTGTCATCACCATCTCTGGACGCATGACCTTCACAAGCAATAAGT
CTATGGAAATTGAGGTCCTGGTGGACGCTGACCCTGTGGTGGACAACTCACAGAAGCGCTACCG
GGCTGCCAGTGCCTTCTTCACCTACGTGTCCCTGAATCAGGAGGGCAAGCCGCTGCCTGTGCCT
CAGCTTGTGCCGGAGACGGAGGACGAGAAGAAGCGTTTTGAAGAAGGCAAAGGCCGCTATCTGC
AGATGAAGGCGAAGCGACAGGGCCATACAGAGCCTCAGCCCTAGATGTCTTCCTCCCTCCCATC
CTGTCCCGTCCTGGGTCAGCACAGTTGTGGCAGTAGTCCTGTGTGCAGTCACTTAGAAGTCGCC
CCCTTGGCCAAACCCCGATTTCCTTTGAGAGCTGGTGTTGTGAAGTACCGTGTGGCAGTGTTAC
CTGTGGCCTGTTCCCAAAACCTGTGCACCAAAGCTTTATTTATATCCCTCCAGTCCCTGCTCCC
ATGTTGTCCCAAAGGCCATCGTGGACACCAGAGCACACTGACTGGCCTGGAGAAGCCAGCACCA
CTAATAAAGCTGCTGTCTGGCTGGA

hide sequence

RefSeq Acc Id:

XM_039109339 ⟹ XP_038965267

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,693,418 - 162,779,309 (+)	NCBI

RefSeq Acc Id:

XM_039109340 ⟹ XP_038965268

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,686,562 - 162,779,309 (+)	NCBI

RefSeq Acc Id:

XM_039109341 ⟹ XP_038965269

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,710,283 - 162,779,309 (+)	NCBI

RefSeq Acc Id:

XM_039109342 ⟹ XP_038965270

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,693,066 - 162,779,309 (+)	NCBI

RefSeq Acc Id:

XM_039109343 ⟹ XP_038965271

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,733,399 - 162,779,309 (+)	NCBI

RefSeq Acc Id:

XR_005504373

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,693,409 - 162,779,309 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001139533	(Get FASTA)	NCBI Sequence Viewer
	NP_037346	(Get FASTA)	NCBI Sequence Viewer
	XP_006239510	(Get FASTA)	NCBI Sequence Viewer
	XP_038965267	(Get FASTA)	NCBI Sequence Viewer
	XP_038965268	(Get FASTA)	NCBI Sequence Viewer
	XP_038965269	(Get FASTA)	NCBI Sequence Viewer
	XP_038965270	(Get FASTA)	NCBI Sequence Viewer
	XP_038965271	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC53202	(Get FASTA)	NCBI Sequence Viewer
	AAH87716	(Get FASTA)	NCBI Sequence Viewer
	BAA19627	(Get FASTA)	NCBI Sequence Viewer
	CAA70512	(Get FASTA)	NCBI Sequence Viewer
	EDL81226	(Get FASTA)	NCBI Sequence Viewer
	EDL81227	(Get FASTA)	NCBI Sequence Viewer
	Q64559	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_037346 ⟸ NM_013214
- Peptide Label:	isoform 2
- UniProtKB:	Q64559 (UniProtKB/Swiss-Prot), F8WG67 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAPPRLIHSAPGLLDTCSQIPPPPSPPPPAVAAKMSGPTTDTPAAIQICRIMRPDDANVAGNVH GGTILKMIEEAGVIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSV EVQVHVLSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQEEEGRKRYEAQKLE RMETKWRNGDIVQPILNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMDEVAGIVAAR HCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDNSQKRYRAASA FFTYVSLNQEGKPLPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHTEPQP hide sequence

RefSeq Acc Id:	NP_001139533 ⟸ NM_001146061
- Peptide Label:	isoform 1
- UniProtKB:	Q64559 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKLLARTLYLWEVGRQVASWSLTSGQECLVLRETWWASMRAVRTRAVHHKPGHCIAMGRIMRPD DANVAGNVHGGTILKMIEEAGVIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAE ITYTSKHSVEVQVHVLSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQEEEGR KRYEAQKLERMETKWRNGDIVQPILNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMD EVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDNS QKRYRAASAFFTYVSLNQEGKPLPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHTEPQP hide sequence

RefSeq Acc Id:

XP_006239510 ⟸ XM_006239448

- Peptide Label:

isoform X3

- Sequence:

show sequence

MRPDDANVAGNVHGGTILKMIEEAGVIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAH
VSAEITYTSKHSVEVQVHVLSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQE
EEGRKRYEAQKLERMETKWRNGDIVQPILNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTM
KLMDEVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPV
VDNSQKRYRAASAFFTYVSLNQEGKPLPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHTEPQ
P

hide sequence

RefSeq Acc Id:

ENSRNOP00000000079 ⟸ ENSRNOT00000000079

RefSeq Acc Id:

ENSRNOP00000014213 ⟸ ENSRNOT00000014213

RefSeq Acc Id:	XP_038965268 ⟸ XM_039109340
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038965270 ⟸ XM_039109342
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038965267 ⟸ XM_039109339
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038965269 ⟸ XM_039109341
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038965271 ⟸ XM_039109343
- Peptide Label:	isoform X4

Protein Domains

HotDog ACOT-type

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694303

Promoter ID:

EPDNEW_R4824

Type:

initiation region

Name:

Acot7_1

Description:

acyl-CoA thioesterase 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4825

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	169,357,614 - 169,357,674	EPDNEW

RGD ID:

13694301

Promoter ID:

EPDNEW_R4825

Type:

initiation region

Name:

Acot7_2

Description:

acyl-CoA thioesterase 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4824

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	169,364,301 - 169,364,361	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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CSV

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628856	AgrOrtholog
Ensembl Genes	ENSRNOG00000010580	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000000079	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000014213	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000000079	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000014213	ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7316866	IMAGE-MGC_LOAD
InterPro	Cytosol_ACT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HOTDOG_ACOT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HotDog_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioestr_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:26759	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105261	IMAGE-MGC_LOAD
NCBI Gene	26759	ENTREZGENE
PANTHER	PTHR11049	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	4HBT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Acot7	PhenoGen
PROSITE	HOTDOG_ACOT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF54637	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	BACH_RAT	UniProtKB/Swiss-Prot
	F8WG67	ENTREZGENE, UniProtKB/TrEMBL
	Q64559	ENTREZGENE
UniProt Secondary	O08652	UniProtKB/Swiss-Prot
	O09041	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Acot7	acyl-CoA thioesterase 7	Bach	brain acyl-CoA hydrolase	Symbol and Name updated	1299863	APPROVED
2005-01-20	Bach	brain acyl-CoA hydrolase			Symbol and Name status set to approved	1299863	APPROVED
2003-02-27	Bach	brain acyl-CoA hydrolase			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)