Casp9 (caspase 9) - Rat Genome Database

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Gene: Casp9 (caspase 9) Rattus norvegicus
Symbol: Casp9
Name: caspase 9
RGD ID: 61867
Description: Enables cysteine-type peptidase activity. Involved in several processes, including glial cell apoptotic process; response to estradiol; and response to ischemia. Predicted to be located in cytosol and nucleus. Predicted to be part of apoptosome and caspase complex. Predicted to be active in mitochondrion. Used to study pre-malignant neoplasm. Biomarker of several diseases, including bronchopulmonary dysplasia; cerebrovascular disease (multiple); heart disease (multiple); kidney disease (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including Parkinson's disease; colorectal cancer; lung non-small cell carcinoma; pancreatic cancer; and type 2 diabetes mellitus. Orthologous to human CASP9 (caspase 9); PARTICIPATES IN intrinsic apoptotic pathway; endometrial cancer pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH (+)-taxifolin; (-)-anisomycin; (-)-citrinin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 25 kDa caspase-9 dominant negative protein; Apaf3; apoptotic protease activating factor 3; apoptotic protease Mch-6; Casp-9-CTD; Casp9_v1; caspase 9, apoptosis-related cysteine peptidase; caspase-9; caspase-9 dominant negative form; caspase-9-carboxyl-terminal divergent; Ice-Lap6; Ice-like apoptotic protease 6; Mch6
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Casp9_v1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.25154,108,872 - 154,126,628 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5154,109,046 - 154,126,626 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5156,793,940 - 156,811,532 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,567,234 - 158,584,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,556,396 - 158,573,978 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05160,356,211 - 160,373,774 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,355,833 - 160,373,778 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05164,067,734 - 164,085,297 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,704,234 - 160,721,796 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15160,714,421 - 160,731,984 (+)NCBI
Celera5152,461,154 - 152,478,717 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)