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Gene: Casp9 (caspase 9) Rattus norvegicus
Symbol: Casp9
Name: caspase 9
Description: Exhibits cysteine-type peptidase activity. Involved in several processes, including glial cell apoptotic process; response to estradiol; and response to ischemia. Localizes to cytosol; mitochondrion; and nucleus. Used to study pre-malignant neoplasm. Biomarker of several diseases, including cerebrovascular disease (multiple); heart disease (multiple); kidney disease (multiple); neurodegenerative disease (multiple); and post-traumatic stress disorder. Human ortholog(s) of this gene implicated in several diseases, including Parkinson's disease; colorectal cancer; lung non-small cell carcinoma; pancreatic cancer; and type 2 diabetes mellitus. Orthologous to human CASP9 (caspase 9); PARTICIPATES IN intrinsic apoptotic pathway; endometrial cancer pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH (+)-taxifolin; (-)-citrinin; (R)-carnitine.
Type: protein-coding
Also known as: 25 kDa caspase-9 dominant negative protein; Apaf3; apoptotic protease activating factor 3; apoptotic protease Mch-6; Casp-9-CTD; Casp9_v1; caspase 9, apoptosis-related cysteine peptidase; caspase-9; caspase-9 dominant negative form; caspase-9-carboxyl-terminal divergent; Ice-Lap6; Ice-like apoptotic protease 6; Mch6
Homo sapiens (human) : CASP9 (caspase 9)  HGNC  Alliance
Mus musculus (house mouse) : Casp9 (caspase 9)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp9 (caspase 9)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP9 (caspase 9)
Canis lupus familiaris (dog) : CASP9 (caspase 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp9 (caspase 9)
Sus scrofa (pig) : CASP9 (caspase 9)
Chlorocebus sabaeus (African green monkey) : CASP9 (caspase 9)
Heterocephalus glaber (naked mole-rat) : Casp9 (caspase 9)
more info ...
Allele / Splice: Casp9_v1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05160,356,211 - 160,373,774 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,355,833 - 160,373,778 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05164,067,734 - 164,085,297 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,704,234 - 160,721,796 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15160,714,421 - 160,731,984 (+)NCBI
Celera5152,461,154 - 152,478,717 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)