Pabpc4 (poly(A) binding protein, cytoplasmic 4) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Pabpc4 (poly(A) binding protein, cytoplasmic 4) Rattus norvegicus
Analyze
Symbol: Pabpc4
Name: poly(A) binding protein, cytoplasmic 4
RGD ID: 1305015
Description: Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Predicted to act upstream of or within myeloid cell development and regulation of mRNA stability. Predicted to be located in cytoplasm. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasmic stress granule; cytosol; and nucleus. Orthologous to human PABPC4 (poly(A) binding protein cytoplasmic 4); PARTICIPATES IN mRNA decay pathway; RNA degradation pathway; RNA transport pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC298510; poly A binding protein, cytoplasmic 4; poly(A) binding protein, cytoplasmic 4 (inducible form); polyadenylate-binding protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Pabpc4-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85140,847,835 - 140,864,089 (+)NCBIGRCr8
mRatBN7.25135,563,142 - 135,578,985 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5135,563,562 - 135,578,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5138,269,597 - 138,284,890 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05140,039,563 - 140,054,856 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05140,046,708 - 140,062,001 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05140,978,893 - 140,994,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5140,979,435 - 140,994,732 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05144,768,558 - 144,784,395 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,599,706 - 142,615,003 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15142,604,839 - 142,620,228 (+)NCBI
Celera5134,102,156 - 134,117,452 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pabpc4RatCharcot-Marie-Tooth disease dominant intermediate C  ISORGD:13127928554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease dominant intermediate CClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pabpc4RatAnimal Disease Models  ISORGD:131279211554173CTD Direct Evidence: marker/mechanismCTDPMID:27602772
Pabpc4Ratlung adenocarcinoma  ISORGD:131279211554173CTD Direct Evidence: marker/mechanismCTDPMID:27602772

1 to 20 of 90 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pabpc4Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PABPC4 mRNA]CTDPMID:31150632
Pabpc4Rat(-)-epigallocatechin 3-gallate multiple interactionsISORGD:13127926480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PABPC4 mRNACTDPMID:22079256
Pabpc4Rat17beta-estradiol increases expressionISORGD:13127936480464Estradiol results in increased expression of PABPC4 mRNACTDPMID:39298647
Pabpc4Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISORGD:131279364804642,2',4,4'-tetrabromodiphenyl ether affects the expression of PABPC4 mRNACTDPMID:30294300
Pabpc4Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISORGD:131279264804642,2',4,4'-tetrabromodiphenyl ether results in decreased expression of PABPC4 proteinCTDPMID:31675489
Pabpc4Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:13127936480464Tetrachlorodibenzodioxin affects the expression of PABPC4 mRNACTDPMID:21570461
Pabpc4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PABPC4 mRNACTDPMID:34747641
Pabpc4Rat2,4-dinitrotoluene affects expressionEXP 64804642,4-dinitrotoluene affects the expression of PABPC4 mRNACTDPMID:21346803
Pabpc4Rat2,6-dinitrotoluene affects expressionEXP 64804642,6-dinitrotoluene affects the expression of PABPC4 mRNACTDPMID:21346803
Pabpc4Rat2-hydroxypropanoic acid increases expressionISORGD:13127926480464Lactic Acid results in increased expression of PABPC4 mRNACTDPMID:30851411
Pabpc4Rat3,4-methylenedioxymethamphetamine decreases expressionISORGD:13127936480464N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of PABPC4 mRNACTDPMID:26251327
Pabpc4Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of PABPC4 proteinCTDPMID:34915118
Pabpc4Rat4,4'-diaminodiphenylmethane increases expressionISORGD:131279364804644,4'-diaminodiphenylmethane results in increased expression of PABPC4 mRNACTDPMID:18648102
Pabpc4Rat4,4'-sulfonyldiphenol increases expressionISORGD:13127936480464bisphenol S results in increased expression of PABPC4 mRNACTDPMID:39298647
Pabpc4Rat4,4'-sulfonyldiphenol increases expressionISORGD:13127926480464bisphenol S results in increased expression of PABPC4 proteinCTDPMID:34186270
Pabpc4Rat4,4'-sulfonyldiphenol decreases methylationISORGD:13127926480464bisphenol S results in decreased methylation of PABPC4 geneCTDPMID:31601247
Pabpc4Rat4-amino-2,6-dinitrotoluene affects expressionEXP 64804644-amino-2,6-dinitrotoluene affects the expression of PABPC4 mRNACTDPMID:21346803
Pabpc4Rat5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expressionEXP 6480464Omeprazole affects the expression of PABPC4 mRNACTDPMID:19483382
Pabpc4Rat6-propyl-2-thiouracil affects expressionEXP 6480464Propylthiouracil affects the expression of PABPC4 mRNACTDPMID:19483382
Pabpc4Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PABPC4 mRNACTDPMID:24780913

1 to 20 of 90 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pabpc4Ratmyeloid cell development acts_upstream_of_or_withinISORGD:13127931624291 PMID:24469397RGDPMID:24469397
Pabpc4Ratregulation of mRNA stability acts_upstream_of_or_withinISORGD:13127931624291 PMID:24469397RGDPMID:24469397

Cellular Component
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pabpc4Ratcytoplasm located_inISORGD:13127921624291 PMID:21940797, PMID:8524242RGDPMID:21940797|PMID:8524242
Pabpc4Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Pabpc4Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Pabpc4Ratcytoplasmic stress granule located_inISORGD:13127921624291 PMID:21940797RGDPMID:21940797
Pabpc4Ratcytoplasmic stress granule is_active_inIBAPANTHER:PTN000610046|PomBase:SPAC57A7.04c|SGD:S000000967|UniProtKB:P11940|UniProtKB:Q133101600115GO_REF:0000033GO_CentralGO_REF:0000033
Pabpc4Ratcytosol is_active_inIBAPANTHER:PTN000610044|UniProtKB:P11940|UniProtKB:P29558|UniProtKB:Q13310|UniProtKB:Q96DU9|UniProtKB:Q9H3611600115GO_REF:0000033GO_CentralGO_REF:0000033
Pabpc4Ratcytosol located_inISORGD:1312792|UniProtKB:Q13310-1|UniProtKB:Q13310-2|UniProtKB:Q13310-31624291 RGDGO_REF:0000052
Pabpc4Ratnucleus is_active_inIBAFB:FBgn0264270|PANTHER:PTN000610044|PomBase:SPAC1610.03c|PomBase:SPAC57A7.04c|PomBase:SPBC29A10.02|SGD:S000000967|UniProtKB:P11940|UniProtKB:Q13310|WB:WBGene00001368|WB:WBGene000073961600115GO_REF:0000033GO_CentralGO_REF:0000033
Pabpc4Ratnucleus located_inISORGD:13127921624291 PMID:21940797RGDPMID:21940797
Pabpc4Ratribonucleoprotein complex part_ofISORGD:13127921624291 PMID:17289661RGDPMID:17289661
Pabpc4Ratribonucleoprotein complex part_ofIBAFB:FBgn0265297|PANTHER:PTN002768817|PomBase:SPAC57A7.04c|SGD:S000004881|UniProtKB:P11940|UniProtKB:Q133101600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 11 of 11 rows

Molecular Function
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pabpc4RatmRNA 3'-UTR binding enablesIBAFB:FBgn0264270|FB:FBgn0265297|MGI:2444477|PANTHER:PTN000610044|UniProtKB:P11940|UniProtKB:Q6XE24|WB:WBGene000063311600115GO_REF:0000033GO_CentralGO_REF:0000033
Pabpc4RatmRNA binding enablesISORGD:13127931624291 PMID:24469397RGDPMID:24469397
Pabpc4Ratnucleic acid binding enablesIEAInterPro:IPR003954|InterPro:IPR0359791600115GO_REF:0000002InterProGO_REF:0000002
Pabpc4Ratpoly(A) binding enablesISORGD:13127921624291 PMID:8524242RGDPMID:8524242
Pabpc4Ratpoly(A) binding enablesIBAFB:FBgn0265297|PANTHER:PTN000610044|PomBase:SPAC1610.03c|PomBase:SPAC57A7.04c|SGD:S000000967|TAIR:locus:2013011|UniProtKB:A0A1L8FTJ1|UniProtKB:A0A8J1LXZ9|UniProtKB:P11940|UniProtKB:Q13310|UniProtKB:Q6XE24|UniProtKB:Q9H3611600115GO_REF:0000033GO_CentralGO_REF:0000033
Pabpc4Ratpoly(C) RNA binding NOT|enablesISORGD:13127921624291 PMID:8524242RGDPMID:8524242
Pabpc4Ratpoly(U) RNA binding enablesISORGD:13127921624291 PMID:8524242RGDPMID:8524242
Pabpc4Ratpoly(U) RNA binding enablesIBAFB:FBgn0264270|PANTHER:PTN000610044|UniProtKB:P11940|UniProtKB:Q13310|UniProtKB:Q6XE241600115GO_REF:0000033GO_CentralGO_REF:0000033
Pabpc4Ratprotein binding enablesISORGD:13127921624291UniProtKB:O60293|UniProtKB:Q8WV24 PMID:11369516, PMID:27871484RGDPMID:11369516|PMID:27871484
Pabpc4RatRNA binding enablesIEAUniRule:UR0004146191600115GO_REF:0000104UniProtGO_REF:0000104
Pabpc4RatRNA binding enablesIEAInterPro:IPR000504|InterPro:IPR002004|InterPro:IPR006515|InterPro:IPR0360531600115GO_REF:0000002InterProGO_REF:0000002
Pabpc4RatRNA binding enablesIEAInterPro:IPR000504|InterPro:IPR0065151600115GO_REF:0000002InterProGO_REF:0000002
Pabpc4RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
1 to 13 of 13 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pabpc4RatmRNA decay pathway  IEA 6907045 KEGGrno:03015
Pabpc4RatRNA degradation pathway  IEA 6907045 KEGGrno:03018
Pabpc4RatRNA transport pathway  IEA 6907045 KEGGrno:03013

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8524242   PMID:12477932   PMID:17289661   PMID:21940797   PMID:22658674   PMID:22681889   PMID:24469397  



Pabpc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85140,847,835 - 140,864,089 (+)NCBIGRCr8
mRatBN7.25135,563,142 - 135,578,985 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5135,563,562 - 135,578,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5138,269,597 - 138,284,890 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05140,039,563 - 140,054,856 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05140,046,708 - 140,062,001 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05140,978,893 - 140,994,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5140,979,435 - 140,994,732 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05144,768,558 - 144,784,395 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,599,706 - 142,615,003 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15142,604,839 - 142,620,228 (+)NCBI
Celera5134,102,156 - 134,117,452 (+)NCBICelera
Cytogenetic Map5q36NCBI
PABPC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38139,560,816 - 39,576,790 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl139,560,709 - 39,576,790 (-)EnsemblGRCh38hg38GRCh38
GRCh37140,026,488 - 40,042,462 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36139,799,075 - 39,815,003 (-)NCBINCBI36Build 36hg18NCBI36
Build 34139,695,580 - 39,711,509NCBI
Celera138,308,199 - 38,324,232 (-)NCBICelera
Cytogenetic Map1p34.3NCBI
HuRef138,145,698 - 38,161,736 (-)NCBIHuRef
CHM1_1140,141,859 - 40,157,895 (-)NCBICHM1_1
T2T-CHM13v2.0139,429,194 - 39,445,168 (-)NCBIT2T-CHM13v2.0
Pabpc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394123,172,722 - 123,192,718 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4123,156,144 - 123,192,718 (+)EnsemblGRCm39 Ensembl
GRCm384123,282,303 - 123,298,925 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4123,262,351 - 123,298,925 (+)EnsemblGRCm38mm10GRCm38
MGSCv374122,960,154 - 122,976,075 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364122,785,214 - 122,801,135 (+)NCBIMGSCv36mm8
Celera4121,615,267 - 121,631,202 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.42NCBI
Pabpc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545217,084,805 - 17,101,026 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545217,083,679 - 17,101,436 (-)NCBIChiLan1.0ChiLan1.0
PABPC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21187,249,907 - 187,265,980 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11186,387,478 - 186,405,157 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0138,846,296 - 38,862,371 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1140,172,651 - 40,188,308 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl140,172,657 - 40,188,308 (-)Ensemblpanpan1.1panPan2
HEYL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1153,242,738 - 3,257,275 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl153,235,611 - 3,303,445 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha153,501,443 - 3,516,003 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0153,362,836 - 3,377,395 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl153,362,852 - 3,377,380 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1153,238,950 - 3,253,501 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0153,299,982 - 3,314,518 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0153,315,601 - 3,330,164 (+)NCBIUU_Cfam_GSD_1.0
Pabpc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505855,627,296 - 55,643,277 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647421,452,005 - 21,468,065 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647421,453,244 - 21,468,059 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PABPC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl695,382,302 - 95,399,080 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1695,382,295 - 95,399,452 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2688,468,836 - 88,485,979 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PABPC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12093,161,868 - 93,177,863 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2093,161,877 - 93,177,839 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603323,501,232 - 23,517,166 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pabpc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476422,069,224 - 22,087,165 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476422,069,218 - 22,086,745 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Pabpc4
34 total Variants

Predicted Target Of
Summary Value
Count of predictions:229
Count of miRNA genes:155
Interacting mature miRNAs:174
Transcripts:ENSRNOT00000056592
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 44 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5129132428143070159Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat

1 to 10 of 44 rows
A001T47  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,578,722 - 135,578,827 (+)MAPPERmRatBN7.2
mRatBN7.2123,119,189 - 3,119,294 (+)MAPPERmRatBN7.2
mRatBN7.25135,578,722 - 135,578,827 (-)MAPPERmRatBN7.2
mRatBN7.2123,119,189 - 3,119,294 (-)MAPPERmRatBN7.2
Rnor_6.05140,994,470 - 140,994,574NCBIRnor6.0
Rnor_6.0123,921,767 - 3,921,871NCBIRnor6.0
Rnor_5.05144,784,133 - 144,784,237UniSTSRnor5.0
Rnor_5.0126,052,808 - 6,052,912UniSTSRnor5.0
RGSC_v3.45142,614,741 - 142,614,845UniSTSRGSC3.4
RGSC_v3.4121,017,446 - 1,017,550UniSTSRGSC3.4
Celera124,938,060 - 4,938,164UniSTS
Celera5134,117,190 - 134,117,294UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map12p12UniSTS
UniSTS:479187  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2123,117,723 - 3,118,323 (-)MAPPERmRatBN7.2
Rnor_6.0123,922,738 - 3,923,337NCBIRnor6.0
Rnor_5.0126,053,779 - 6,054,378UniSTSRnor5.0
RGSC_v3.4121,018,417 - 1,019,016UniSTSRGSC3.4
Celera124,936,594 - 4,937,193UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map12p12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 22 of 22 rows
RefSeq Transcripts NM_001100538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC088337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC166452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 22 of 22 rows

Ensembl Acc Id: ENSRNOT00000056592   ⟹   ENSRNOP00000053432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5135,563,562 - 135,578,979 (+)Ensembl
Rnor_6.0 Ensembl5140,979,435 - 140,994,732 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106428   ⟹   ENSRNOP00000090731
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5135,563,562 - 135,578,979 (+)Ensembl
RefSeq Acc Id: NM_001100538   ⟹   NP_001094008
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,848,792 - 140,864,089 (+)NCBI
mRatBN7.25135,563,687 - 135,578,985 (+)NCBI
Rnor_6.05140,979,435 - 140,994,732 (+)NCBI
Rnor_5.05144,768,558 - 144,784,395 (+)NCBI
RGSC_v3.45142,599,706 - 142,615,003 (+)RGD
Celera5134,102,156 - 134,117,452 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238798   ⟹   XP_006238860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,847,835 - 140,863,928 (+)NCBI
mRatBN7.25135,563,143 - 135,578,985 (+)NCBI
Rnor_6.05140,978,893 - 140,994,732 (+)NCBI
Rnor_5.05144,768,558 - 144,784,395 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238799   ⟹   XP_006238861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,847,835 - 140,864,089 (+)NCBI
mRatBN7.25135,563,142 - 135,578,985 (+)NCBI
Rnor_6.05140,978,893 - 140,994,732 (+)NCBI
Rnor_5.05144,768,558 - 144,784,395 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238800   ⟹   XP_006238862
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,847,835 - 140,863,928 (+)NCBI
mRatBN7.25135,563,144 - 135,578,985 (+)NCBI
Rnor_6.05140,978,894 - 140,994,732 (+)NCBI
Rnor_5.05144,768,558 - 144,784,395 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238801   ⟹   XP_006238863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,847,835 - 140,863,928 (+)NCBI
mRatBN7.25135,563,143 - 135,578,985 (+)NCBI
Rnor_6.05140,978,894 - 140,994,732 (+)NCBI
Rnor_5.05144,768,558 - 144,784,395 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109613   ⟹   XP_038965541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,847,835 - 140,864,089 (+)NCBI
mRatBN7.25135,563,143 - 135,578,985 (+)NCBI
RefSeq Acc Id: XM_039109614   ⟹   XP_038965542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,854,787 - 140,863,928 (+)NCBI
mRatBN7.25135,569,685 - 135,578,985 (+)NCBI
RefSeq Acc Id: XM_063287433   ⟹   XP_063143503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,847,835 - 140,864,089 (+)NCBI
RefSeq Acc Id: XM_063287434   ⟹   XP_063143504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,847,835 - 140,864,089 (+)NCBI
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: NP_001094008   ⟸   NM_001100538
- UniProtKB: A0A8J8XGC4 (UniProtKB/TrEMBL),   A6IS24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238860   ⟸   XM_006238798
- Peptide Label: isoform X1
- UniProtKB: B2GUY3 (UniProtKB/TrEMBL),   G3V9N0 (UniProtKB/TrEMBL),   A6IS26 (UniProtKB/TrEMBL),   A6IS24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238861   ⟸   XM_006238799
- Peptide Label: isoform X2
- UniProtKB: A6IS25 (UniProtKB/TrEMBL),   A6IS24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238862   ⟸   XM_006238800
- Peptide Label: isoform X4
- UniProtKB: A6IS24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238863   ⟸   XM_006238801
- Peptide Label: isoform X6
- UniProtKB: A6IS24 (UniProtKB/TrEMBL)
- Sequence:
PABC   RRM

Name Modeler Protein Id AA Range Protein Structure
AF-G3V9N0-F1-model_v2 AlphaFold G3V9N0 1-644 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 44 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-40011 BioCyc
Ensembl Genes ENSRNOG00000015642 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056592 ENTREZGENE
  ENSRNOT00000056592.4 UniProtKB/TrEMBL
  ENSRNOT00000106428 ENTREZGENE
  ENSRNOT00000106428.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
  c-terminal domain of poly(a) binding protein UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7366578 IMAGE-MGC_LOAD
  IMAGE:8372968 IMAGE-MGC_LOAD
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  PABP-dom UniProtKB/TrEMBL
  PABP_1234 UniProtKB/TrEMBL
  PABP_HYD UniProtKB/TrEMBL
  PABP_RRM1 UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM2_I_PABPs UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  RRM_dom_euk UniProtKB/TrEMBL
KEGG Report rno:298510 UniProtKB/TrEMBL
MGC_CLONE MGC:109607 IMAGE-MGC_LOAD
  MGC:187687 IMAGE-MGC_LOAD
NCBI Gene 298510 ENTREZGENE
PANTHER RNA BINDING PROTEIN UniProtKB/TrEMBL
Pfam PABP UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PhenoGen Pabpc4 PhenoGen
PROSITE PABC UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015642 RatGTEx
SMART PolyA UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
Superfamily-SCOP PABP_HYD UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A8I6ACF6_RAT UniProtKB/TrEMBL
  A0A8J8XGC4 ENTREZGENE, UniProtKB/TrEMBL
  A6IS24 ENTREZGENE, UniProtKB/TrEMBL
  A6IS25 ENTREZGENE, UniProtKB/TrEMBL
  A6IS26 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 44 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-12-15 Pabpc4  poly(A) binding protein, cytoplasmic 4  Pabpc4  poly A binding protein, cytoplasmic 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Pabpc4  poly A binding protein, cytoplasmic 4  Pabpc4_predicted  poly A binding protein, cytoplasmic 4 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Pabpc4_predicted  poly A binding protein, cytoplasmic 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED