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Gene: Slc2a1 (solute carrier family 2 member 1) Rattus norvegicus
Symbol: Slc2a1
Name: solute carrier family 2 member 1
RGD ID: 3704
Description: Exhibits kinase binding activity and transmembrane transporter activity. Involved in several processes, including cellular hyperosmotic response; cellular response to mechanical stimulus; and dehydroascorbic acid transport. Localizes to several cellular components, including Z disc; basolateral plasma membrane; and intercalated disc. Biomarker of hypertension; hypothyroidism; and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in brain disease (multiple); carbohydrate metabolic disorder; myelomeningocele; obesity; and type 2 diabetes mellitus. Orthologous to human SLC2A1 (solute carrier family 2 member 1); PARTICIPATES IN facilitative sugar transporter mediated glucose transport pathway; Glut1 deficiency syndrome pathway; hypoxia inducible factor pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 1-naphthyl isothiocyanate.
Type: protein-coding
Also known as: glucose transporter type 1, erythrocyte/brain; GLUT-1; Glut1; GLUTB; GTG1; Gtg3; RATGTG1; solute carrier family 2 (facilitated glucose transporter) member 1; solute carrier family 2 (facilitated glucose transporter), member 1; Solute carrier family 2 a 1 (facilitated glucose transporter) brain; solute carrier family 2, facilitated glucose transporter member 1; solute carrier family 2, member 1; solute carrier family 2,member 1
Homo sapiens (human) : SLC2A1 (solute carrier family 2 member 1)  HGNC  Alliance
Mus musculus (house mouse) : Slc2a1 (solute carrier family 2 (facilitated glucose transporter), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc2a1 (solute carrier family 2 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC2A1 (solute carrier family 2 member 1)
Canis lupus familiaris (dog) : SLC2A1 (solute carrier family 2 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc2a1 (solute carrier family 2 member 1)
Sus scrofa (pig) : SLC2A1 (solute carrier family 2 member 1)
Chlorocebus sabaeus (African green monkey) : SLC2A1 (solute carrier family 2 member 1)
Heterocephalus glaber (naked mole-rat) : Slc2a1 (solute carrier family 2 member 1)
more info ...
Is Marker For: QTLs:   Bp103  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05138,154,677 - 138,182,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5138,154,673 - 138,182,897 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05141,964,114 - 141,992,634 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45139,690,801 - 139,719,021 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15139,696,029 - 139,724,247 (+)NCBI
Celera5131,243,786 - 131,272,021 (+)NCBICelera
Cytogenetic Map5q36NCBI
RH 3.4 Map5865.0RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc2a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3704
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.