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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3704
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a1
Name: solute carrier family 2 member 1
Acc ID: CHEBI:16842
Term: formaldehyde
Definition: An aldehyde resulting from the formal oxidation of methanol.
Chemical ID: MESH:D005557
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a1increases expressionISOSLC2A1 (Homo sapiens)6480464CTDFormaldehyde results in increased expression of SLC2A1 mRNA; Formaldehyde results in increased expression of SLC2A1 proteinPMID:36116563
Slc2a1multiple interactionsISOSlc2a1 (Mus musculus)6480464CTD2-amino-3-(4'-N,N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide inhibits the reaction [[Formaldehyde co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC2A1 protein]; 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Formaldehyde promotes the reaction [ovalbumin-alum results in increased expression of SLC2A1 mRNA]]; [Formaldehyde co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC2A1 protein; Formaldehyde promotes the reaction [ovalbumin-alum results in increased expression of SLC2A1 mRNA]PMID:37105513
Slc2a1multiple interactionsISOSLC2A1 (Homo sapiens)6480464CTDDeferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]PMID:36116563
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