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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3704
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a1
Name: solute carrier family 2 member 1
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a1decreases expressionEXP 6480464CTDmethylmercuric chloride results in decreased expression of SLC2A1 proteinPMID:31850806
Slc2a1multiple interactionsEXP 6480464CTD2-Methoxyestradiol promotes the reaction [methylmercuric chloride results in decreased expression of SLC2A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of SLC2A1 protein]; cobaltous chloride inhibits the reaction [methylmercuric chloride results in decreased expression of SLC2A1 protein]; protocatechuic acid inhibits the reaction [methylmercuric chloride results in decreased expression of SLC2A1 protein]PMID:31850806
Slc2a1decreases expressionISOSLC2A1 (Homo sapiens)6480464CTDmethylmercuric chloride results in decreased expression of SLC2A1 mRNAPMID:23179753 PMID:27188386
Slc2a1increases expressionISOSlc2a1 (Mus musculus)6480464CTDmethylmercuric chloride results in increased expression of SLC2A1 proteinPMID:15649634
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