Pla2g5 (phospholipase A2, group V) - Rat Genome Database

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Gene: Pla2g5 (phospholipase A2, group V) Rattus norvegicus
Analyze
Symbol: Pla2g5
Name: phospholipase A2, group V
RGD ID: 62051
Description: Enables calcium-dependent phospholipase A2 activity and heparin binding activity. Involved in several processes, including arachidonic acid secretion; leukotriene biosynthetic process; and platelet activating factor biosynthetic process. Located in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in familial benign fleck retina. Orthologous to human PLA2G5 (phospholipase A2 group V); PARTICIPATES IN alpha-linolenic acid metabolic pathway; arachidonic acid metabolic pathway; ether lipid metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calcium-dependent phospholipase A2; group V phospholipase A2; MGC93513; phosphatidylcholine 2-acylhydrolase 5; phospholipase A2 group V; phospholipase A2, group 5; PLA2-10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,324,628 - 156,393,065 (-)NCBIGRCr8
mRatBN7.25151,041,339 - 151,109,433 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,041,340 - 151,062,658 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5153,738,735 - 153,760,037 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,513,041 - 155,534,343 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,495,070 - 155,516,077 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,247,601 - 157,268,968 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,247,781 - 157,268,903 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05160,988,968 - 161,030,066 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45157,619,703 - 157,640,971 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15157,629,741 - 157,651,010 (-)NCBI
Celera5149,429,045 - 149,450,195 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP,ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
ammonium chloride  (EXP)
arachidonic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benazepril  (EXP)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-D-glucosamine  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (EXP)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
Cuprizon  (EXP)
dibutyl phthalate  (EXP,ISO)
diiodine  (ISO)
doxorubicin  (EXP,ISO)
enzalutamide  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (EXP)
gentamycin  (EXP)
glycidol  (EXP)
hydrogen peroxide  (ISO)
icosanoid  (ISO)
isoliquiritigenin  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP)
leukotriene C4  (ISO)
lipopolysaccharide  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
N-nitrosodiethylamine  (ISO)
naphthalene  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
pentanal  (ISO)
peptidoglycan  (ISO)
piperonyl butoxide  (ISO)
progesterone  (EXP,ISO)
propanal  (ISO)
prostaglandin E2  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sarin  (ISO)
silicon dioxide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Cloning, expression and partial characterization of a novel rat phospholipase A2. Chen J, etal., Biochim Biophys Acta 1994 Nov 17;1215(1-2):115-20.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. The functions of five distinct mammalian phospholipase A2S in regulating arachidonic acid release. Type IIa and type V secretory phospholipase A2S are functionally redundant and act in concert with cytosolic phospholipase A2. Murakami M, etal., J Biol Chem. 1998 Jun 5;273(23):14411-23.
7. Distinct arachidonate-releasing functions of mammalian secreted phospholipase A2s in human embryonic kidney 293 and rat mastocytoma RBL-2H3 cells through heparan sulfate shuttling and external plasma membrane mechanisms. Murakami M, etal., J Biol Chem. 2001 Mar 30;276(13):10083-96. Epub 2000 Dec 5.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
15. Group IIA and group V secretory phospholipase A(2): quantitative analysis of expression and secretion and determination of the localization and routing in rat mesangial cells. van der Helm HA, etal., Biochim Biophys Acta. 2001 Jan 15;1530(1):86-96.
Additional References at PubMed
PMID:8943302   PMID:11830583   PMID:12477932   PMID:14962950   PMID:15003994   PMID:15489334   PMID:16407308   PMID:19342668   PMID:20432503   PMID:22837859   PMID:23533611   PMID:23567287  
PMID:24910243  


Genomics

Comparative Map Data
Pla2g5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,324,628 - 156,393,065 (-)NCBIGRCr8
mRatBN7.25151,041,339 - 151,109,433 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,041,340 - 151,062,658 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5153,738,735 - 153,760,037 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,513,041 - 155,534,343 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,495,070 - 155,516,077 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,247,601 - 157,268,968 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,247,781 - 157,268,903 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05160,988,968 - 161,030,066 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45157,619,703 - 157,640,971 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15157,629,741 - 157,651,010 (-)NCBI
Celera5149,429,045 - 149,450,195 (-)NCBICelera
Cytogenetic Map5q36NCBI
PLA2G5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38120,028,408 - 20,091,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl120,028,179 - 20,091,911 (+)EnsemblGRCh38hg38GRCh38
GRCh37120,396,687 - 20,418,404 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36120,269,288 - 20,290,981 (+)NCBINCBI36Build 36hg18NCBI36
Build 34120,142,143 - 20,162,959NCBI
Celera118,719,822 - 18,741,514 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef118,642,531 - 18,664,224 (+)NCBIHuRef
CHM1_1120,506,410 - 20,528,103 (+)NCBICHM1_1
T2T-CHM13v2.0119,852,033 - 19,915,547 (+)NCBIT2T-CHM13v2.0
Pla2g5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394138,526,558 - 138,590,784 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4138,526,555 - 138,590,793 (-)EnsemblGRCm39 Ensembl
GRCm384138,799,247 - 138,863,562 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4138,799,244 - 138,863,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv374138,355,162 - 138,419,384 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,071,333 - 138,091,286 (-)NCBIMGSCv36mm8
Celera4140,584,350 - 140,649,745 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.57NCBI
Pla2g5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955452710,271 - 723,142 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955452662,281 - 721,507 (+)NCBIChiLan1.0ChiLan1.0
PLA2G5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,027,174 - 207,048,964 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,144,002 - 206,165,768 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,983,104 - 19,046,834 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1120,026,361 - 20,089,840 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl120,068,110 - 20,089,840 (+)Ensemblpanpan1.1panPan2
PLA2G5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1278,762,851 - 78,781,642 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl278,762,852 - 78,781,983 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,276,435 - 75,295,216 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,329,011 - 79,347,745 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,329,015 - 79,347,767 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,148,347 - 76,167,055 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,154,883 - 77,173,638 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,225,847 - 78,234,080 (-)NCBIUU_Cfam_GSD_1.0
Pla2g5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505840,307,140 - 40,326,035 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364746,131,884 - 6,150,819 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364746,131,915 - 6,150,810 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA2G5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl678,302,062 - 78,376,220 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1678,365,697 - 78,376,383 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2672,541,431 - 72,565,649 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLA2G5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120112,465,341 - 112,487,082 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20112,464,033 - 112,487,089 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660333,696,670 - 3,719,131 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pla2g5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247645,196,215 - 5,207,232 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247645,196,215 - 5,207,138 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pla2g5
434 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:409
Count of miRNA genes:211
Interacting mature miRNAs:248
Transcripts:ENSRNOT00000022716
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat

Markers in Region
RH143028  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,051,526 - 151,051,656 (+)MAPPERmRatBN7.2
Rnor_6.05157,257,796 - 157,257,925NCBIRnor6.0
Rnor_5.05160,999,155 - 160,999,284UniSTSRnor5.0
RGSC_v3.45157,629,864 - 157,629,993UniSTSRGSC3.4
Celera5149,439,206 - 149,439,335UniSTS
RH 3.4 Map51034.1UniSTS
Cytogenetic Map5q36UniSTS
RH144651  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,055,414 - 151,055,607 (+)MAPPERmRatBN7.2
Rnor_6.05157,261,684 - 157,261,876NCBIRnor6.0
Rnor_5.05161,003,043 - 161,003,235UniSTSRnor5.0
RGSC_v3.45157,633,752 - 157,633,944UniSTSRGSC3.4
Celera5149,443,094 - 149,443,286UniSTS
RH 3.4 Map51033.2UniSTS
Cytogenetic Map5q36UniSTS
RH134706  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,041,368 - 151,041,585 (+)MAPPERmRatBN7.2
Rnor_6.05157,247,638 - 157,247,854NCBIRnor6.0
Rnor_5.05160,988,998 - 160,989,214UniSTSRnor5.0
RGSC_v3.45157,619,707 - 157,619,923UniSTSRGSC3.4
Celera5149,429,049 - 149,429,265UniSTS
RH 3.4 Map51033.5UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 25 14
Low 3 6 16 8 18 8 6 7 52 20 11 6
Below cutoff 8 25 17 1 17 2 4 18 27 6 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000022716   ⟹   ENSRNOP00000022715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5151,041,340 - 151,062,658 (-)Ensembl
Rnor_6.0 Ensembl5157,247,781 - 157,268,903 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098996   ⟹   ENSRNOP00000086169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5151,041,340 - 151,048,608 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113045   ⟹   ENSRNOP00000087975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5151,041,340 - 151,049,135 (-)Ensembl
RefSeq Acc Id: NM_017174   ⟹   NP_058870
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,324,654 - 156,345,922 (-)NCBI
mRatBN7.25151,041,365 - 151,062,634 (-)NCBI
Rnor_6.05157,247,634 - 157,268,903 (-)NCBI
Rnor_5.05160,988,968 - 161,030,066 (-)NCBI
RGSC_v3.45157,619,703 - 157,640,971 (-)RGD
Celera5149,429,045 - 149,450,195 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239139   ⟹   XP_006239201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,324,628 - 156,345,982 (-)NCBI
mRatBN7.25151,041,339 - 151,062,691 (-)NCBI
Rnor_6.05157,247,601 - 157,268,968 (-)NCBI
Rnor_5.05160,988,968 - 161,030,066 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764210   ⟹   XP_008762432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,324,628 - 156,338,165 (-)NCBI
mRatBN7.25151,041,339 - 151,054,290 (-)NCBI
Rnor_6.05157,247,601 - 157,260,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063287254   ⟹   XP_063143324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,324,628 - 156,393,065 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_058870   ⟸   NM_017174
- Peptide Label: precursor
- UniProtKB: Q6DQ96 (UniProtKB/Swiss-Prot),   P51433 (UniProtKB/Swiss-Prot),   A6ITI7 (UniProtKB/TrEMBL),   A0A8I6A5J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239201   ⟸   XM_006239139
- Peptide Label: isoform X1
- UniProtKB: Q6DQ96 (UniProtKB/Swiss-Prot),   P51433 (UniProtKB/Swiss-Prot),   A6ITI7 (UniProtKB/TrEMBL),   A0A8I6A5J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762432   ⟸   XM_008764210
- Peptide Label: isoform X1
- UniProtKB: Q6DQ96 (UniProtKB/Swiss-Prot),   P51433 (UniProtKB/Swiss-Prot),   A6ITI7 (UniProtKB/TrEMBL),   A0A8I6A5J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000022715   ⟸   ENSRNOT00000022716
RefSeq Acc Id: ENSRNOP00000087975   ⟸   ENSRNOT00000113045
RefSeq Acc Id: ENSRNOP00000086169   ⟸   ENSRNOT00000098996
RefSeq Acc Id: XP_063143324   ⟸   XM_063287254
- Peptide Label: isoform X1
- UniProtKB: Q6DQ96 (UniProtKB/Swiss-Prot),   P51433 (UniProtKB/Swiss-Prot),   A6ITI7 (UniProtKB/TrEMBL)
Protein Domains
Phospholipase A2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P51433-F1-model_v2 AlphaFold P51433 1-137 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62051 AgrOrtholog
BioCyc Gene G2FUF-39440 BioCyc
Ensembl Genes ENSRNOG00000016838 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055022859 UniProtKB/Swiss-Prot
  ENSRNOG00060031903 UniProtKB/Swiss-Prot
  ENSRNOG00065021857 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022716 ENTREZGENE
  ENSRNOT00000022716.6 UniProtKB/Swiss-Prot
  ENSRNOT00000098996.1 UniProtKB/TrEMBL
  ENSRNOT00000113045.1 UniProtKB/TrEMBL
  ENSRNOT00055039251 UniProtKB/Swiss-Prot
  ENSRNOT00060055322 UniProtKB/Swiss-Prot
  ENSRNOT00065037215 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.90.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7192819 IMAGE-MGC_LOAD
InterPro PLipase_A2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_A2_Asp_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_A2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_A2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_A2_His_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29354 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93513 IMAGE-MGC_LOAD
NCBI Gene 29354 ENTREZGENE
PANTHER PHOSPHOLIPASE A2 GROUP V UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11716 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Phospholip_A2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pla2g5 PhenoGen
PRINTS PHPHLIPASEA2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PA2_ASP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PA2_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016838 RatGTEx
  ENSRNOG00055022859 RatGTEx
  ENSRNOG00060031903 RatGTEx
  ENSRNOG00065021857 RatGTEx
SMART PA2c UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48619 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC210430
UniProt A0A8I6A4T3_RAT UniProtKB/TrEMBL
  A0A8I6A5J8 ENTREZGENE, UniProtKB/TrEMBL
  A6ITI7 ENTREZGENE, UniProtKB/TrEMBL
  A6ITI8_RAT UniProtKB/TrEMBL
  P51433 ENTREZGENE, UniProtKB/Swiss-Prot
  Q6DQ96 ENTREZGENE
UniProt Secondary Q6DQ96 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Pla2g5  phospholipase A2, group V    phospholipase A2, group 5  Name updated 1299863 APPROVED
2002-06-10 Pla2g5  phospholipase A2, group 5      Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference