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Gene: Urod (uroporphyrinogen decarboxylase) Rattus norvegicus
Symbol: Urod
Name: uroporphyrinogen decarboxylase
RGD ID: 3946
Description: Exhibits ferrous iron binding activity and uroporphyrinogen decarboxylase activity. Involved in several processes, including porphyrin-containing compound metabolic process; response to estradiol; and response to fungicide. Localizes to cytosol. Biomarker of porphyria and porphyria cutanea tarda. Human ortholog(s) of this gene implicated in porphyria cutanea tarda. Orthologous to human UROD (uroporphyrinogen decarboxylase); PARTICIPATES IN heme biosynthetic pathway; acute intermittent porphyria pathway; erythropoietic porphyria pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: porphyrinogen carboxy-lyase; porphyrinogen carboxylase; UPD; URO-D; uroporphyrinogen III decarboxylase
Homo sapiens (human) : UROD (uroporphyrinogen decarboxylase)  HGNC  Alliance
Mus musculus (house mouse) : Urod (uroporphyrinogen decarboxylase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Urod (uroporphyrinogen decarboxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : UROD (uroporphyrinogen decarboxylase)
Canis lupus familiaris (dog) : UROD (uroporphyrinogen decarboxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Urod (uroporphyrinogen decarboxylase)
Sus scrofa (pig) : UROD (uroporphyrinogen decarboxylase)
Chlorocebus sabaeus (African green monkey) : UROD (uroporphyrinogen decarboxylase)
Heterocephalus glaber (naked mole-rat) : Urod (uroporphyrinogen decarboxylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05135,855,429 - 135,859,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,855,433 - 135,859,643 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,650,563 - 139,654,649 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,296,410 - 137,300,496 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15137,301,638 - 137,305,678 (-)NCBI
Celera5128,991,227 - 128,995,309 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Urod
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3946
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.