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Gene: Urod (uroporphyrinogen decarboxylase) Rattus norvegicus
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Symbol: Urod
Name: uroporphyrinogen decarboxylase
Description: Exhibits ferrous iron binding activity and uroporphyrinogen decarboxylase activity. Involved in several processes, including porphyrin-containing compound metabolic process; response to estradiol; and response to ethanol. Localizes to the cytosol. Biomarker of porphyria cutanea tarda. Human ortholog(s) of this gene implicated in porphyria cutanea tarda. Orthologous to human UROD (uroporphyrinogen decarboxylase); PARTICIPATES IN heme biosynthetic pathway; acute intermittent porphyria pathway; erythropoietic porphyria pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: porphyrinogen carboxy-lyase; porphyrinogen carboxylase; UPD; URO-D; uroporphyrinogen III decarboxylase
Orthologs:
Homo sapiens (human) : UROD (uroporphyrinogen decarboxylase)  HGNC  Alliance
Mus musculus (house mouse) : Urod (uroporphyrinogen decarboxylase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Urod (uroporphyrinogen decarboxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : UROD (uroporphyrinogen decarboxylase)
Canis lupus familiaris (dog) : UROD (uroporphyrinogen decarboxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Urod (uroporphyrinogen decarboxylase)
Sus scrofa (pig) : UROD (uroporphyrinogen decarboxylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05135,855,429 - 135,859,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05139,650,563 - 139,654,649 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,296,410 - 137,300,496 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15137,301,638 - 137,305,678 (-)NCBI
Celera5128,991,227 - 128,995,309 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Urod
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3946
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.