Nudc (nuclear distribution C, dynein complex regulator) - Rat Genome Database

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Gene: Nudc (nuclear distribution C, dynein complex regulator) Rattus norvegicus
Analyze
Symbol: Nudc
Name: nuclear distribution C, dynein complex regulator
RGD ID: 3215
Description: Predicted to enable unfolded protein binding activity. Involved in nuclear migration and response to peptide hormone. Located in Golgi apparatus. Orthologous to human NUDC (nuclear distribution C, dynein complex regulator); PARTICIPATES IN M phase pathway; INTERACTS WITH 2,6-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: c15; clone 15; LOC100911422; nuclear distribution C homolog; nuclear distribution C homolog (A. nidulans); nuclear distribution gene C homolog; nuclear distribution gene C homolog (A. nidulans); nuclear distribution gene C homolog (Aspergillus); nuclear distribution protein C homolog; nuclear migration protein nudC; nuclear migration protein nudC-like; nudC nuclear distribution protein; Silg92
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25145,758,006 - 145,771,390 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl5145,758,002 - 145,771,425 (-)Ensembl
Rnor_6.05151,754,723 - 151,768,104 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5151,754,716 - 151,768,123 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05155,443,982 - 155,457,375 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45151,535,900 - 151,550,041 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15151,545,941 - 151,560,080 (+)NCBI
Celera5144,178,324 - 144,191,960 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Lynch syndrome  (ISO)
obesity  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
cytosol  (IEA,ISO)
Golgi apparatus  (IDA)
microtubule  (IEA)
midbody  (IEA,ISO,ISS)
mitotic spindle  (ISO,ISS)
nucleus  (IEA)
spindle  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Characterization of a prolactin-inducible gene, clone 15, in T cells. Axtell SM, etal., Mol Endocrinol 1995 Mar;9(3):312-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Expression of RNUDC, a potential nuclear movement protein, in mammalian cells: localization to the Golgi apparatus. Morris SM and Yu-Lee LY, Exp Cell Res. 1998 Jan 10;238(1):23-32.
4. The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC. Morris SM, etal., Curr Biol. 1998 May 7;8(10):603-6.
5. A prolactin-inducible T cell gene product is structurally similar to the Aspergillus nidulans nuclear movement protein NUDC. Morris SM, etal., Mol Endocrinol. 1997 Feb;11(2):229-36.
6. The lissencephaly protein Lis1 is present in motile mammalian cilia and requires outer arm dynein for targeting to Chlamydomonas flagella. Pedersen LB, etal., J Cell Sci. 2007 Mar 1;120(Pt 5):858-67.
7. Reactome: A Knowledgebase of Biological Processes Reactome
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
12. Phosphorylation of Numb regulates its interaction with the clathrin-associated adaptor AP-2. Tokumitsu H, etal., FEBS Lett. 2006 Oct 16;580(24):5797-801. Epub 2006 Sep 27.
Additional References at PubMed
PMID:15489334   PMID:21771589   PMID:25002582   PMID:25468996  


Genomics

Comparative Map Data
Nudc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25145,758,006 - 145,771,390 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl5145,758,002 - 145,771,425 (-)Ensembl
Rnor_6.05151,754,723 - 151,768,104 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5151,754,716 - 151,768,123 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05155,443,982 - 155,457,375 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45151,535,900 - 151,550,041 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15151,545,941 - 151,560,080 (+)NCBI
Celera5144,178,324 - 144,191,960 (-)NCBICelera
Cytogenetic Map5q36NCBI
NUDC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,900,161 - 26,946,871 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl126,900,238 - 26,946,871 (+)EnsemblGRCh38hg38GRCh38
GRCh37127,248,234 - 27,273,362 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,120,811 - 27,145,474 (+)NCBINCBI36hg18NCBI36
Build 34126,932,365 - 26,957,029NCBI
Celera125,645,312 - 25,669,980 (+)NCBI
Cytogenetic Map1p36.11NCBI
HuRef125,501,783 - 25,526,939 (+)NCBIHuRef
CHM1_1127,361,578 - 27,386,708 (+)NCBICHM1_1
T2T-CHM13v2.0126,759,801 - 26,784,927 (+)NCBI
Nudc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394133,259,853 - 133,273,338 (-)NCBIGRCm39mm39
GRCm39 Ensembl4133,259,853 - 133,273,307 (-)Ensembl
GRCm384133,532,542 - 133,546,027 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4133,532,542 - 133,545,996 (-)EnsemblGRCm38mm10GRCm38
MGSCv374133,088,457 - 133,101,942 (-)NCBIGRCm37mm9NCBIm37
MGSCv364132,804,620 - 132,825,130 (-)NCBImm8
Celera4131,701,670 - 131,715,113 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
Nudc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554526,261,286 - 6,278,393 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554526,261,500 - 6,278,393 (+)NCBIChiLan1.0ChiLan1.0
NUDC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1127,239,780 - 27,263,952 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,239,574 - 27,267,360 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0126,184,232 - 26,207,412 (+)NCBIMhudiblu_PPA_v0panPan3
NUDC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,207,945 - 73,222,027 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,208,146 - 73,222,020 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha269,785,990 - 69,800,075 (-)NCBI
ROS_Cfam_1.0273,771,708 - 73,785,789 (-)NCBI
ROS_Cfam_1.0 Ensembl273,771,713 - 73,785,782 (-)Ensembl
UMICH_Zoey_3.1270,596,734 - 70,610,791 (-)NCBI
UNSW_CanFamBas_1.0271,602,099 - 71,616,194 (-)NCBI
UU_Cfam_GSD_1.0272,605,104 - 72,619,184 (-)NCBI
Nudc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505845,503,199 - 45,516,577 (+)NCBI
SpeTri2.0NW_00493647411,327,986 - 11,341,357 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUDC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl684,237,737 - 84,252,046 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1684,238,695 - 84,252,046 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2677,808,882 - 77,822,246 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NUDC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120105,817,738 - 105,842,188 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl20105,817,213 - 105,842,180 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603310,590,371 - 10,615,395 (+)NCBIVero_WHO_p1.0
Nudc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476410,908,956 - 10,925,547 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462476410,889,020 - 10,925,547 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH131321  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25145,758,148 - 145,758,687 (+)MAPPERmRatBN7.2
Rnor_6.05151,754,866 - 151,755,404NCBIRnor6.0
Rnor_5.05156,118,681 - 156,119,219UniSTSRnor5.0
Rnor_5.05155,444,125 - 155,444,663UniSTSRnor5.0
RGSC_v3.45151,549,360 - 151,549,898UniSTSRGSC3.4
Celera5144,178,467 - 144,179,005UniSTS
RH 3.4 Map5979.5UniSTS
Cytogenetic Map5q36UniSTS
RH125442  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25145,758,231 - 145,759,722 (+)MAPPERmRatBN7.2
mRatBN7.24165,491,162 - 165,491,423 (+)MAPPERmRatBN7.2
Rnor_6.04165,967,242 - 165,967,502NCBIRnor6.0
Rnor_6.05151,754,949 - 151,756,439NCBIRnor6.0
Rnor_5.04228,531,728 - 228,531,989NCBIRnor5.0
Rnor_5.05155,444,207 - 155,445,698NCBIRnor5.0
Rnor_5.05156,118,763 - 156,120,254NCBIRnor5.0
RGSC_v3.44169,537,403 - 169,537,663UniSTSRGSC3.4
RGSC_v3.45151,548,325 - 151,549,815UniSTSRGSC3.4
Celera5144,178,550 - 144,180,040UniSTS
Celera4154,088,559 - 154,088,819UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map5q36UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:212
Count of miRNA genes:141
Interacting mature miRNAs:157
Transcripts:ENSRNOT00000009933
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 21 19 4 19 3 64 16 35 7
Low 17 36 22 15 22 8 8 10 19 6 4 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000079380   ⟹   ENSRNOP00000073414
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5145,758,003 - 145,771,425 (-)Ensembl
Rnor_6.0 Ensembl5151,754,716 - 151,768,123 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090180   ⟹   ENSRNOP00000071599
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5145,758,003 - 145,769,987 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097974   ⟹   ENSRNOP00000087838
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5145,758,002 - 145,771,415 (-)Ensembl
RefSeq Acc Id: NM_017271   ⟹   NP_058967
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25145,758,006 - 145,771,390 (-)NCBI
Rnor_6.05151,754,723 - 151,768,104 (-)NCBI
Rnor_5.05155,443,982 - 155,457,375 (-)NCBI
RGSC_v3.45151,535,900 - 151,550,041 (+)RGD
Celera5144,178,324 - 144,191,960 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058967 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH65581 (Get FASTA)   NCBI Sequence Viewer  
  CAA57825 (Get FASTA)   NCBI Sequence Viewer  
  EDL80674 (Get FASTA)   NCBI Sequence Viewer  
  Q63525 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058967   ⟸   NM_017271
- UniProtKB: Q63525 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073414   ⟸   ENSRNOT00000079380
RefSeq Acc Id: ENSRNOP00000087838   ⟸   ENSRNOT00000097974
RefSeq Acc Id: ENSRNOP00000071599   ⟸   ENSRNOT00000090180
Protein Domains
CS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0V8-F1-model_v2 AlphaFold A0A0G2K0V8 1-279 view protein structure
AF-Q63525-F1-model_v2 AlphaFold Q63525 1-332 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694116
Promoter ID:EPDNEW_R4641
Type:initiation region
Name:Nudc_1
Description:nuclear distribution C, dynein complex regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05151,768,139 - 151,768,199EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3215 AgrOrtholog
BioCyc Gene G2FUF-39630 BioCyc
Ensembl Genes ENSRNOG00000051720 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000071599.2 UniProtKB/TrEMBL
  ENSRNOP00000073414 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000087838.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000079380 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000090180.2 UniProtKB/TrEMBL
  ENSRNOT00000097974.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.790 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5623848 IMAGE-MGC_LOAD
InterPro CS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NuDC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NudC_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NudC_N_dom UniProtKB/Swiss-Prot
KEGG Report rno:29648 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72493 IMAGE-MGC_LOAD
NCBI Gene 29648 ENTREZGENE
PANTHER PTHR12356 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NuDC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nudc_N UniProtKB/Swiss-Prot
  PF04969 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nudc PhenoGen
PROSITE PS51203 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49764 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC208127
UniProt A0A0G2K0V8_RAT UniProtKB/TrEMBL
  A0A8I6A9J2_RAT UniProtKB/TrEMBL
  NUDC_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Nudc  nuclear distribution C, dynein complex regulator  LOC100911422  nuclear migration protein nudC-like  Data Merged 737654 PROVISIONAL
2016-06-22 Nudc  nuclear distribution C, dynein complex regulator  Nudc  nudC nuclear distribution protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-14 Nudc  nudC nuclear distribution protein  Nudc  nuclear distribution C homolog (A. nidulans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-14 Nudc  nudC nuclear distribution protein  Nudc  nudC nuclear distribution protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-05 Nudc  nuclear distribution C homolog (A. nidulans)  Nudc  nuclear distribution gene C homolog (A. nidulans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911422  nuclear migration protein nudC-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-12-15 Nudc  nuclear distribution gene C homolog (A. nidulans)  Nudc  nuclear distribution gene C homolog (Aspergillus)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Nudc  nuclear distribution gene C homolog (Aspergillus)       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_homology has high similarity to the Aspergillus nidulans nuclear movement protein NUDC 69912