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GENE - TERM ANNOTATION REPORT

RGD ID: 3215
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nudc
Name: nuclear distribution C, dynein complex regulator
Acc ID: DOID:9970
Term: obesity
Definition: An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Obesity "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nudc ISONUDC (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: NR0B2-related condition | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity due to SIM1 deficiency | ClinVar Annotator: match by term: Obesity, mild, early-onsetPMID:11136233 PMID:20233523 PMID:25741868 PMID:28492532 PMID:33094510
Nudc ISONUDC (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, mild, early-onsetPMID:11136233 PMID:25741868 PMID:28492532 PMID:33094510
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