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Gene: Cyp4b1 (cytochrome P450, family 4, subfamily b, polypeptide 1) Rattus norvegicus
Symbol: Cyp4b1
Name: cytochrome P450, family 4, subfamily b, polypeptide 1
RGD ID: 2480
Description: Predicted to have monooxygenase activity. Involved in biphenyl metabolic process. Localizes to intracellular membrane-bounded organelle. Orthologous to human CYP4B1 (cytochrome P450 family 4 subfamily B member 1); PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
Also known as: CYPIVB1; cytochrome P450 4B1; cytochrome P450 isozyme 5; cytochrome P450 L-2; Cytochrome P450 subfamily IVB polypeptide 1; Cytochrome P450 subfamily IVB polypeptide 1 see also D5M4Rp1; cytochrome P450, subfamily 4B, polypeptide 1; Cytochrome P450, subfamily IVB, polypeptide 1; P450 L-2; P450-isozyme 5
Homo sapiens (human) : CYP4B1 (cytochrome P450 family 4 subfamily B member 1)  HGNC  Alliance
Mus musculus (house mouse) : Cyp4b1 (cytochrome P450, family 4, subfamily b, polypeptide 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102012414 (cytochrome P450 4B1)
Pan paniscus (bonobo/pygmy chimpanzee) : CYP4B1 (cytochrome P450 family 4 subfamily B member 1)
Canis lupus familiaris (dog) : CYP4B1 (cytochrome P450 family 4 subfamily B member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101955242 (cytochrome P450 4B1)
Sus scrofa (pig) : LOC100523909 (cytochrome P450 4B1)
Chlorocebus sabaeus (African green monkey) : CYP4B1 (cytochrome P450 family 4 subfamily B member 1)
Heterocephalus glaber (naked mole-rat) : LOC101725929 (cytochrome P450 4B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05134,508,728 - 134,526,103 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5134,508,730 - 134,526,089 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05138,299,551 - 138,316,860 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45135,917,327 - 135,934,636 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15135,922,552 - 135,939,862 (-)NCBI
Celera5127,676,727 - 127,694,036 (-)NCBICelera
Cytogenetic Map5q35NCBI
RH 3.4 Map5823.3RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cyp4b1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2480
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.