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Gene: CYP4B1 (cytochrome P450 family 4 subfamily B member 1) Homo sapiens

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Symbol:

CYP4B1

Name:

cytochrome P450 family 4 subfamily B member 1

RGD ID:

736540

HGNC Page

HGNC:2644

Description:

Predicted to enable monooxygenase activity and oxygen binding activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in endoplasmic reticulum membrane.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

CYPIVB1; cytochrome P450 4B1; cytochrome P450, family 4, subfamily B, polypeptide 1; cytochrome p450, subfamily 4b, polypeptide 1; cytochrome P450, subfamily IVB, polypeptide 1; cytochrome P450-HP; microsomal monooxygenase; P-450HP

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

NCBI Annotation Information:

Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	46,799,046 - 46,819,413 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	46,757,838 - 46,819,413 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	47,264,718 - 47,285,085 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	47,037,257 - 47,057,608 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	46,976,761 - 46,997,105	NCBI
Celera	1	45,552,027 - 45,572,396 (+)	NCBI		Celera
Cytogenetic Map	1	p33	NCBI
HuRef	1	45,380,284 - 45,400,633 (+)	NCBI		HuRef
CHM1_1	1	47,381,383 - 47,401,714 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CYP4B1	Human	chronic obstructive pulmonary disease		IAGP	RGD:156185658	8554872	ClinVar Annotator: match by term: Pulmonary disease, chronic obstructive, susceptibility to	ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CYP4B1	Human	autism spectrum disorder		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:35663546
CYP4B1	Human	urinary bladder cancer		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:18713828

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CYP4B1	Human	1,2-dimethylhydrazine	decreases expression	ISO	RGD:10457	6480464	1,2-Dimethylhydrazine results in decreased expression of CYP4B1 mRNA	CTD	PMID:22206623
CYP4B1	Human	1-naphthyl isothiocyanate	decreases expression	ISO	RGD:2480	6480464	1-Naphthylisothiocyanate results in decreased expression of CYP4B1 mRNA	CTD	PMID:30723492
CYP4B1	Human	17alpha-ethynylestradiol	decreases expression	ISO	RGD:2480	6480464	Ethinyl Estradiol results in decreased expression of CYP4B1 mRNA	CTD	PMID:16174780\|PMID:17351261
CYP4B1	Human	17alpha-ethynylestradiol	decreases expression	ISO	RGD:10457	6480464	Ethinyl Estradiol results in decreased expression of CYP4B1 mRNA	CTD	PMID:16174780\|PMID:17942748
CYP4B1	Human	17alpha-ethynylestradiol	multiple interactions	ISO	RGD:10457	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of CYP4B1 mRNA	CTD	PMID:17942748
CYP4B1	Human	17alpha-ethynylestradiol	affects expression	ISO	RGD:10457	6480464	Ethinyl Estradiol affects the expression of CYP4B1 mRNA	CTD	PMID:17555576
CYP4B1	Human	17beta-estradiol	multiple interactions	EXP		6480464	[Estradiol co-treated with TGFB1 protein] results in decreased expression of CYP4B1 mRNA; [Progesterone co-treated with more ...	CTD	PMID:17404688\|PMID:30165855
CYP4B1	Human	17beta-estradiol	decreases expression	EXP		6480464	Estradiol results in decreased expression of CYP4B1 mRNA	CTD	PMID:31614463
CYP4B1	Human	17beta-estradiol	decreases expression	ISO	RGD:2480	6480464	Estradiol results in decreased expression of CYP4B1 mRNA	CTD	PMID:26945725
CYP4B1	Human	17beta-estradiol	decreases expression	ISO	RGD:10457	6480464	Estradiol results in decreased expression of CYP4B1 mRNA	CTD	PMID:14664709\|PMID:39298647
CYP4B1	Human	2,2',4,4'-Tetrabromodiphenyl ether	increases expression	ISO	RGD:2480	6480464	2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CYP4B1 mRNA	CTD	PMID:20566336
CYP4B1	Human	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:2480	6480464	Tetrachlorodibenzodioxin results in decreased expression of CYP4B1 mRNA	CTD	PMID:21215274
CYP4B1	Human	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:2480	6480464	Tetrachlorodibenzodioxin results in increased expression of CYP4B1 mRNA	CTD	PMID:32109520
CYP4B1	Human	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:10457	6480464	Tetrachlorodibenzodioxin results in decreased expression of CYP4B1 mRNA	CTD	PMID:28213091
CYP4B1	Human	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of CYP4B1 mRNA	CTD	PMID:16985168\|PMID:20106945\|PMID:26159488
CYP4B1	Human	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	RGD:10457	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of CYP4B1 mRNA; Tetrachlorodibenzodioxin promotes the more ...	CTD	PMID:17942748\|PMID:28213091
CYP4B1	Human	2,3,7,8-Tetrachlorodibenzofuran	increases expression	ISO	RGD:2480	6480464	2,3,7,8-tetrachlorodibenzofuran results in increased expression of CYP4B1 mRNA	CTD	PMID:32109520
CYP4B1	Human	2-naphthylamine	increases metabolic processing	ISO	RGD:2480	6480464	CYP4B1 protein results in increased metabolism of 2-Naphthylamine	CTD	PMID:9310344
CYP4B1	Human	2-naphthylamine	increases metabolic processing	ISO	RGD:10457	6480464	CYP4B1 protein results in increased metabolism of 2-Naphthylamine	CTD	PMID:9310344
CYP4B1	Human	3,3',4,4',5-pentachlorobiphenyl	decreases expression	ISO	RGD:2480	6480464	3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP4B1 mRNA	CTD	PMID:23196670
CYP4B1	Human	3,3'-Dichlorobenzidine	increases metabolic processing	ISO	RGD:2480	6480464	CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine	CTD	PMID:9310344
CYP4B1	Human	3,3'-Dichlorobenzidine	increases metabolic processing	ISO	RGD:10457	6480464	CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine	CTD	PMID:9310344
CYP4B1	Human	3,3'-Dichlorobenzidine	multiple interactions	ISO	RGD:10457	6480464	lauric acid inhibits the reaction [CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine]	CTD	PMID:9310344
CYP4B1	Human	3,4-methylenedioxymethamphetamine	increases expression	ISO	RGD:10457	6480464	N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of CYP4B1 mRNA	CTD	PMID:26251327
CYP4B1	Human	3,4-methylenedioxymethamphetamine	increases methylation	ISO	RGD:10457	6480464	N-Methyl-3,4-methylenedioxyamphetamine results in increased methylation of CYP4B1 promoter	CTD	PMID:26251327
CYP4B1	Human	3-chloropropane-1,2-diol	multiple interactions	ISO	RGD:10457	6480464	[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of CYP4B1 mRNA	CTD	PMID:33187795
CYP4B1	Human	3-isobutyl-1-methyl-7H-xanthine	multiple interactions	EXP		6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...	CTD	PMID:28628672
CYP4B1	Human	3-methylbenzyl alcohol	decreases activity	ISO	RGD:2480	6480464	3-methylbenzyl alcohol results in decreased activity of CYP4B1 protein	CTD	PMID:12791539
CYP4B1	Human	3-methylcholanthrene	increases expression	ISO	RGD:2480	6480464	Methylcholanthrene results in increased expression of CYP4B1 mRNA	CTD	PMID:23273579
CYP4B1	Human	3-methyleneindolenine	multiple interactions	EXP		6480464	[CYP4B1 protein results in increased metabolism of Skatole] which results in increased chemical synthesis of more ...	CTD	PMID:20187624
CYP4B1	Human	3H-1,2-dithiole-3-thione	decreases expression	ISO	RGD:2480	6480464	1,2-dithiol-3-thione results in decreased expression of CYP4B1 mRNA	CTD	PMID:19162173
CYP4B1	Human	4,4'-sulfonyldiphenol	affects methylation	ISO	RGD:10457	6480464	bisphenol S affects the methylation of CYP4B1 gene	CTD	PMID:31683443
CYP4B1	Human	4-Ipomeanol	decreases response to substance	ISO	RGD:10457	6480464	CYP4B1 gene mutant form results in decreased susceptibility to 4-ipomeanol	CTD	PMID:23748241
CYP4B1	Human	4-Ipomeanol	affects binding	ISO	RGD:2480	1626415	4-Ipomeanol binds to Cyp4b1 protein	RGD
CYP4B1	Human	4-Ipomeanol	multiple interactions	ISO	RGD:10457	6480464	CYP4B1 protein results in increased susceptibility to and results in increased metabolism of and results more ...	CTD	PMID:23748241
CYP4B1	Human	4-Ipomeanol	affects metabolic processing	ISO	RGD:2480	6480464	CYP4B1 protein affects the metabolism of 4-ipomeanol	CTD	PMID:8248926
CYP4B1	Human	4-Ipomeanol	increases response to substance	ISO	RGD:2480	6480464	CYP4B1 protein results in increased susceptibility to 4-ipomeanol	CTD	PMID:8248926
CYP4B1	Human	6-propyl-2-thiouracil	decreases expression	ISO	RGD:2480	6480464	Propylthiouracil results in decreased expression of CYP4B1 mRNA	CTD	PMID:30047161
CYP4B1	Human	acrolein	multiple interactions	EXP		6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ...	CTD	PMID:32699268
CYP4B1	Human	aflatoxin B1	decreases expression	EXP		6480464	Aflatoxin B1 results in decreased expression of CYP4B1 mRNA	CTD	PMID:32234424
CYP4B1	Human	all-trans-retinoic acid	increases expression	EXP		6480464	Tretinoin results in increased expression of CYP4B1 mRNA	CTD	PMID:16249480
CYP4B1	Human	all-trans-retinoic acid	decreases expression	EXP		6480464	Tretinoin results in decreased expression of CYP4B1 mRNA	CTD	PMID:16985168
CYP4B1	Human	alpha-pinene	multiple interactions	EXP		6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ...	CTD	PMID:32699268
CYP4B1	Human	alpha-Zearalanol	multiple interactions	ISO	RGD:2480	6480464	[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of CYP4B1 mRNA	CTD	PMID:35163327
CYP4B1	Human	amitrole	decreases expression	ISO	RGD:2480	6480464	Amitrole results in decreased expression of CYP4B1 mRNA	CTD	PMID:30047161
CYP4B1	Human	ammonium chloride	affects expression	ISO	RGD:2480	6480464	Ammonium Chloride affects the expression of CYP4B1 mRNA	CTD	PMID:16483693
CYP4B1	Human	amphotericin B	decreases expression	EXP		6480464	Amphotericin B analog results in decreased expression of CYP4B1 mRNA	CTD	PMID:28534445
CYP4B1	Human	aristolochic acid A	multiple interactions	ISO	RGD:2480	6480464	[aristolochic acid I co-treated with aristolochic acid II] results in increased expression of CYP4B1 mRNA	CTD	PMID:23912714
CYP4B1	Human	Azoxymethane	multiple interactions	ISO	RGD:10457	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP4B1 more ...	CTD	PMID:29950665
CYP4B1	Human	benzo[a]pyrene	decreases expression	EXP		6480464	Benzo(a)pyrene results in decreased expression of CYP4B1 mRNA	CTD	PMID:20106945
CYP4B1	Human	benzo[a]pyrene	increases expression	ISO	RGD:10457	6480464	Benzo(a)pyrene results in increased expression of CYP4B1 protein	CTD	PMID:34472326
CYP4B1	Human	benzo[a]pyrene	increases methylation	EXP		6480464	Benzo(a)pyrene results in increased methylation of CYP4B1 exon	CTD	PMID:27901495
CYP4B1	Human	benzo[a]pyrene	affects methylation	EXP		6480464	Benzo(a)pyrene affects the methylation of CYP4B1 3' UTR; Benzo(a)pyrene affects the methylation of CYP4B1 promoter	CTD	PMID:27901495
CYP4B1	Human	benzo[a]pyrene	decreases expression	ISO	RGD:10457	6480464	Benzo(a)pyrene results in decreased expression of CYP4B1 mRNA	CTD	PMID:22228805\|PMID:23735875
CYP4B1	Human	benzo[b]fluoranthene	decreases expression	ISO	RGD:10457	6480464	benzo(b)fluoranthene results in decreased expression of CYP4B1 mRNA	CTD	PMID:26377693
CYP4B1	Human	Benzo[ghi]perylene	increases expression	EXP		6480464	1,12-benzoperylene results in increased expression of CYP4B1	CTD	PMID:27234499
CYP4B1	Human	Benzo[ghi]perylene	multiple interactions	EXP		6480464	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of CYP4B1]	CTD	PMID:27234499
CYP4B1	Human	beta-naphthoflavone	decreases expression	EXP		6480464	beta-Naphthoflavone results in decreased expression of CYP4B1 mRNA	CTD	PMID:16985168\|PMID:22258563
CYP4B1	Human	bezafibrate	affects expression	ISO	RGD:2480	6480464	Bezafibrate affects the expression of CYP4B1 mRNA	CTD	PMID:17719200
CYP4B1	Human	bifenthrin	decreases expression	ISO	RGD:10457	6480464	bifenthrin results in decreased expression of CYP4B1 mRNA	CTD	PMID:26071804
CYP4B1	Human	bisphenol A	multiple interactions	ISO	RGD:2480	6480464	[bisphenol A co-treated with Testosterone] results in decreased expression of CYP4B1 mRNA	CTD	PMID:26496021
CYP4B1	Human	bisphenol A	increases expression	ISO	RGD:10457	6480464	bisphenol A results in increased expression of CYP4B1 mRNA	CTD	PMID:33221593
CYP4B1	Human	bisphenol A	multiple interactions	EXP		6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...	CTD	PMID:28628672
CYP4B1	Human	buspirone	increases expression	ISO	RGD:2480	6480464	Buspirone results in increased expression of CYP4B1 mRNA	CTD	PMID:24136188
CYP4B1	Human	cadmium dichloride	affects expression	ISO	RGD:2480	6480464	Cadmium Chloride affects the expression of CYP4B1 mRNA	CTD	PMID:22110744
CYP4B1	Human	cadmium dichloride	decreases expression	EXP		6480464	Cadmium Chloride results in decreased expression of CYP4B1 mRNA	CTD	PMID:38568856
CYP4B1	Human	cadmium dichloride	decreases expression	ISO	RGD:10457	6480464	Cadmium Chloride results in decreased expression of CYP4B1 mRNA	CTD	PMID:11958953
CYP4B1	Human	cadmium dichloride	increases expression	EXP		6480464	Cadmium Chloride results in increased expression of CYP4B1 mRNA	CTD	PMID:12160620
CYP4B1	Human	caffeine	increases expression	EXP		6480464	Caffeine results in increased expression of CYP4B1 mRNA	CTD	PMID:18444173
CYP4B1	Human	calcidiol	decreases expression	ISO	RGD:2480	6480464	Calcifediol deficiency results in decreased expression of CYP4B1 mRNA	CTD	PMID:17293106
CYP4B1	Human	calcitriol	decreases expression	EXP		6480464	Calcitriol results in decreased expression of CYP4B1 mRNA	CTD	PMID:27107558
CYP4B1	Human	carbon nanotube	decreases expression	ISO	RGD:10457	6480464	Nanotubes, Carbon analog results in decreased expression of CYP4B1 mRNA; Nanotubes, Carbon results in decreased more ...	CTD	PMID:25554681\|PMID:25620056
CYP4B1	Human	chlorpyrifos	increases expression	ISO	RGD:10457	6480464	Chlorpyrifos results in increased expression of CYP4B1 mRNA	CTD	PMID:37019170
CYP4B1	Human	ciguatoxin CTX1B	affects expression	ISO	RGD:10457	6480464	Ciguatoxins affects the expression of CYP4B1 mRNA	CTD	PMID:18353800
CYP4B1	Human	cobalt atom	decreases expression	ISO	RGD:10457	6480464	Cobalt results in decreased expression of CYP4B1 mRNA	CTD	PMID:34468815
CYP4B1	Human	cobalt dichloride	increases expression	ISO	RGD:2480	6480464	cobaltous chloride results in increased expression of CYP4B1 mRNA	CTD	PMID:24386269
CYP4B1	Human	copper atom	increases expression	ISO	RGD:2480	6480464	Copper results in increased expression of CYP4B1 mRNA	CTD	PMID:22465980
CYP4B1	Human	copper(0)	increases expression	ISO	RGD:2480	6480464	Copper results in increased expression of CYP4B1 mRNA	CTD	PMID:22465980
CYP4B1	Human	copper(II) chloride	decreases expression	EXP		6480464	cupric chloride results in decreased expression of CYP4B1 mRNA	CTD	PMID:38568856
CYP4B1	Human	Cuprizon	decreases expression	ISO	RGD:2480	6480464	Cuprizone results in decreased expression of CYP4B1 mRNA	CTD	PMID:27523638
CYP4B1	Human	cyclosporin A	decreases expression	EXP		6480464	Cyclosporine results in decreased expression of CYP4B1 mRNA	CTD	PMID:20106945
CYP4B1	Human	dexamethasone	multiple interactions	EXP		6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...	CTD	PMID:28628672
CYP4B1	Human	dextran sulfate	multiple interactions	ISO	RGD:10457	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP4B1 more ...	CTD	PMID:29950665
CYP4B1	Human	dodecanoic acid	multiple interactions	ISO	RGD:10457	6480464	lauric acid inhibits the reaction [CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine]	CTD	PMID:9310344
CYP4B1	Human	elemental selenium	increases expression	ISO	RGD:2480	6480464	Selenium deficiency results in increased expression of CYP4B1 mRNA	CTD	PMID:11444866
CYP4B1	Human	epoxiconazole	increases expression	ISO	RGD:2480	6480464	epoxiconazole results in increased expression of CYP4B1 mRNA	CTD	PMID:25182419
CYP4B1	Human	ethanol	increases expression	ISO	RGD:2480	6480464	Ethanol results in increased expression of CYP4B1 mRNA	CTD	PMID:23273579
CYP4B1	Human	ethanol	decreases expression	ISO	RGD:2480	6480464	Ethanol results in decreased expression of CYP4B1 mRNA	CTD	PMID:15353170
CYP4B1	Human	ethyl methanesulfonate	increases expression	EXP		6480464	Ethyl Methanesulfonate results in increased expression of CYP4B1 mRNA	CTD	PMID:23649840
CYP4B1	Human	fenofibrate	multiple interactions	ISO	RGD:2480	6480464	[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA	CTD	PMID:18253720
CYP4B1	Human	fenthion	increases expression	ISO	RGD:10457	6480464	Fenthion results in increased expression of CYP4B1 mRNA	CTD	PMID:34813904
CYP4B1	Human	flavonoids	decreases expression	ISO	RGD:2480	6480464	Flavonoids results in decreased expression of CYP4B1 mRNA	CTD	PMID:18035473
CYP4B1	Human	flutamide	decreases expression	ISO	RGD:2480	6480464	Flutamide results in decreased expression of CYP4B1 mRNA	CTD	PMID:24136188
CYP4B1	Human	folic acid	decreases expression	ISO	RGD:10457	6480464	Folic Acid results in decreased expression of CYP4B1 mRNA	CTD	PMID:25629700
CYP4B1	Human	genistein	decreases expression	EXP		6480464	Genistein results in decreased expression of CYP4B1 mRNA	CTD	PMID:18444173
CYP4B1	Human	genistein	increases expression	ISO	RGD:10457	6480464	Genistein results in increased expression of CYP4B1 mRNA	CTD	PMID:32186404
CYP4B1	Human	glycidol	multiple interactions	ISO	RGD:10457	6480464	[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of CYP4B1 mRNA	CTD	PMID:33187795
CYP4B1	Human	indometacin	multiple interactions	EXP		6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...	CTD	PMID:28628672
CYP4B1	Human	irinotecan	affects expression	ISO	RGD:2480	6480464	Irinotecan affects the expression of CYP4B1 mRNA	CTD	PMID:20097248
CYP4B1	Human	ketoconazole	increases expression	ISO	RGD:2480	6480464	Ketoconazole results in increased expression of CYP4B1 mRNA	CTD	PMID:37077353
CYP4B1	Human	kojic acid	multiple interactions	ISO	RGD:2480	6480464	[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA	CTD	PMID:18544905
CYP4B1	Human	kojic acid	multiple interactions	ISO	RGD:10457	6480464	[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CYP4B1 mRNA	CTD	PMID:17917374
CYP4B1	Human	lead diacetate	decreases expression	EXP		6480464	lead acetate results in decreased expression of CYP4B1 mRNA	CTD	PMID:38568856
CYP4B1	Human	levofloxacin	increases expression	ISO	RGD:2480	6480464	Levofloxacin results in increased expression of CYP4B1 mRNA	CTD	PMID:24136188
CYP4B1	Human	m-tolualdehyde	affects activity	ISO	RGD:2480	6480464	3-methylbenzaldehyde affects the activity of CYP4B1 protein	CTD	PMID:12791539
CYP4B1	Human	m-xylene	affects activity	ISO	RGD:2480	6480464	3-xylene affects the activity of CYP4B1 protein	CTD	PMID:15204773
CYP4B1	Human	m-xylene	decreases activity	ISO	RGD:2480	6480464	3-xylene results in decreased activity of CYP4B1 protein	CTD	PMID:12791539\|PMID:8598570
CYP4B1	Human	methimazole	decreases expression	ISO	RGD:2480	6480464	Methimazole results in decreased expression of CYP4B1 mRNA	CTD	PMID:30047161
CYP4B1	Human	methylparaben	decreases expression	EXP		6480464	methylparaben results in decreased expression of CYP4B1 mRNA	CTD	PMID:38568856
CYP4B1	Human	mifepristone	decreases expression	EXP		6480464	Mifepristone results in decreased expression of CYP4B1 mRNA	CTD	PMID:17584828
CYP4B1	Human	Muraglitazar	increases expression	ISO	RGD:2480	6480464	muraglitazar results in increased expression of CYP4B1 mRNA	CTD	PMID:21515302
CYP4B1	Human	N-nitrosodiethylamine	multiple interactions	ISO	RGD:2480	6480464	[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA; more ...	CTD	PMID:18253720\|PMID:18544905\|PMID:18977376
CYP4B1	Human	N-nitrosodiethylamine	multiple interactions	ISO	RGD:10457	6480464	[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CYP4B1 mRNA	CTD	PMID:17917374
CYP4B1	Human	nevirapine	increases expression	ISO	RGD:2480	6480464	Nevirapine metabolite results in increased expression of CYP4B1 mRNA	CTD	PMID:23947594
CYP4B1	Human	O-methyleugenol	decreases expression	EXP		6480464	methyleugenol results in decreased expression of CYP4B1 mRNA	CTD	PMID:32234424
CYP4B1	Human	okadaic acid	decreases expression	EXP		6480464	Okadaic Acid results in decreased expression of CYP4B1 mRNA	CTD	PMID:38832940
CYP4B1	Human	orphenadrine	affects expression	ISO	RGD:2480	6480464	Orphenadrine affects the expression of CYP4B1 mRNA	CTD	PMID:23665939
CYP4B1	Human	oxycodone	increases expression	ISO	RGD:2480	6480464	Oxycodone results in increased expression of CYP4B1 mRNA	CTD	PMID:23439660
CYP4B1	Human	ozone	decreases expression	ISO	RGD:10457	6480464	Ozone results in decreased expression of CYP4B1 mRNA	CTD	PMID:16183385
CYP4B1	Human	ozone	multiple interactions	ISO	RGD:10457	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ...	CTD	PMID:34911549
CYP4B1	Human	ozone	multiple interactions	EXP		6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ...	CTD	PMID:32699268
CYP4B1	Human	paracetamol	affects expression	ISO	RGD:10457	6480464	Acetaminophen affects the expression of CYP4B1 mRNA	CTD	PMID:17562736
CYP4B1	Human	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of CYP4B1 mRNA	CTD	PMID:29067470
CYP4B1	Human	pentane-2,3-dione	decreases expression	ISO	RGD:2480	6480464	2,3-pentanedione results in decreased expression of CYP4B1 mRNA	CTD	PMID:25710175
CYP4B1	Human	perfluorooctane-1-sulfonic acid	increases expression	ISO	RGD:2480	6480464	perfluorooctane sulfonic acid results in increased expression of CYP4B1 mRNA	CTD	PMID:18692542
CYP4B1	Human	perfluorooctanoic acid	increases expression	ISO	RGD:2480	6480464	perfluorooctanoic acid results in increased expression of CYP4B1 mRNA	CTD	PMID:16221955\|PMID:28511854
CYP4B1	Human	perfluorooctanoic acid	multiple interactions	ISO	RGD:2480	6480464	[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of CYP4B1 mRNA	CTD	PMID:35163327
CYP4B1	Human	phenobarbital	increases expression	ISO	RGD:2480	6480464	Phenobarbital results in increased expression of CYP4B1 mRNA	CTD	PMID:12082028\|PMID:23273579
CYP4B1	Human	phenobarbital	decreases expression	ISO	RGD:2480	6480464	Phenobarbital results in decreased expression of CYP4B1 mRNA	CTD	PMID:30047161
CYP4B1	Human	phenobarbital	affects expression	ISO	RGD:10457	6480464	Phenobarbital affects the expression of CYP4B1 mRNA	CTD	PMID:23091169
CYP4B1	Human	pirinixic acid	decreases expression	ISO	RGD:10457	6480464	pirinixic acid results in decreased expression of CYP4B1 mRNA	CTD	PMID:18467677
CYP4B1	Human	pirinixic acid	increases expression	ISO	RGD:10457	6480464	pirinixic acid results in increased expression of CYP4B1 mRNA	CTD	PMID:17426115\|PMID:23811191
CYP4B1	Human	pirinixic acid	multiple interactions	ISO	RGD:10457	6480464	PPARA protein promotes the reaction [pirinixic acid results in decreased expression of CYP4B1 mRNA]	CTD	PMID:18467677
CYP4B1	Human	potassium dichromate	increases expression	ISO	RGD:10457	6480464	Potassium Dichromate results in increased expression of CYP4B1 mRNA	CTD	PMID:23608068
CYP4B1	Human	pregnenolone 16alpha-carbonitrile	decreases expression	ISO	RGD:2480	6480464	Pregnenolone Carbonitrile results in decreased expression of CYP4B1 mRNA	CTD	PMID:15596064
CYP4B1	Human	progesterone	multiple interactions	EXP		6480464	[Progesterone co-treated with Estradiol] results in increased expression of CYP4B1 mRNA	CTD	PMID:17404688
CYP4B1	Human	progesterone	increases expression	EXP		6480464	Progesterone results in increased expression of CYP4B1 mRNA	CTD	PMID:17404688
CYP4B1	Human	propylparaben	decreases expression	EXP		6480464	propylparaben results in decreased expression of CYP4B1 mRNA	CTD	PMID:38568856
CYP4B1	Human	resveratrol	multiple interactions	EXP		6480464	[Plant Extracts co-treated with Resveratrol] results in decreased expression of CYP4B1 mRNA	CTD	PMID:23557933
CYP4B1	Human	ritonavir	affects expression	ISO	RGD:2480	6480464	Ritonavir affects the expression of CYP4B1 mRNA	CTD	PMID:17719200
CYP4B1	Human	ritonavir	decreases expression	ISO	RGD:2480	6480464	Ritonavir results in decreased expression of CYP4B1 mRNA	CTD	PMID:17719200
CYP4B1	Human	rotenone	increases expression	ISO	RGD:2480	6480464	Rotenone results in increased expression of CYP4B1 mRNA	CTD	PMID:28374803
CYP4B1	Human	selenium atom	increases expression	ISO	RGD:2480	6480464	Selenium deficiency results in increased expression of CYP4B1 mRNA	CTD	PMID:11444866
CYP4B1	Human	silicon dioxide	decreases expression	EXP		6480464	Silicon Dioxide results in decreased expression of CYP4B1 mRNA	CTD	PMID:22300531
CYP4B1	Human	skatole	multiple interactions	EXP		6480464	[CYP4B1 protein results in increased metabolism of Skatole] which results in increased chemical synthesis of more ...	CTD	PMID:20187624
CYP4B1	Human	skatole	increases metabolic processing	EXP		6480464	CYP4B1 protein results in increased metabolism of Skatole	CTD	PMID:20187624
CYP4B1	Human	sodium arsenite	affects methylation	EXP		6480464	sodium arsenite affects the methylation of CYP4B1 gene	CTD	PMID:28589171
CYP4B1	Human	sodium arsenite	decreases expression	EXP		6480464	sodium arsenite results in decreased expression of CYP4B1 mRNA	CTD	PMID:29301061\|PMID:38568856
CYP4B1	Human	succimer	multiple interactions	ISO	RGD:10457	6480464	[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CYP4B1 mRNA	CTD	PMID:26378955
CYP4B1	Human	sulfadimethoxine	decreases expression	ISO	RGD:2480	6480464	Sulfadimethoxine results in decreased expression of CYP4B1 mRNA	CTD	PMID:30047161
CYP4B1	Human	sulindac	multiple interactions	ISO	RGD:2480	6480464	[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CYP4B1 mRNA	CTD	PMID:20371263
CYP4B1	Human	tamoxifen	affects expression	ISO	RGD:10457	6480464	Tamoxifen affects the expression of CYP4B1 mRNA	CTD	PMID:17555576
CYP4B1	Human	terephthalic acid	increases expression	ISO	RGD:2480	6480464	terephthalic acid results in increased expression of CYP4B1 mRNA	CTD	PMID:16673812
CYP4B1	Human	Tesaglitazar	increases expression	ISO	RGD:2480	6480464	tesaglitazar results in increased expression of CYP4B1 mRNA	CTD	PMID:21515302
CYP4B1	Human	testosterone	increases expression	ISO	RGD:2480	6480464	Testosterone results in increased expression of CYP4B1 mRNA	CTD	PMID:11311483
CYP4B1	Human	testosterone	multiple interactions	ISO	RGD:2480	6480464	[bisphenol A co-treated with Testosterone] results in decreased expression of CYP4B1 mRNA	CTD	PMID:26496021
CYP4B1	Human	tetrachloromethane	affects expression	ISO	RGD:2480	6480464	Carbon Tetrachloride affects the expression of CYP4B1 mRNA	CTD	PMID:16239168
CYP4B1	Human	Theaflavin 3,3'-digallate	affects expression	EXP		6480464	theaflavin-3,3'-digallate affects the expression of CYP4B1 mRNA	CTD	PMID:34925699
CYP4B1	Human	thiram	decreases expression	EXP		6480464	Thiram results in decreased expression of CYP4B1 mRNA	CTD	PMID:38568856
CYP4B1	Human	titanium dioxide	decreases expression	ISO	RGD:2480	6480464	titanium dioxide results in decreased expression of CYP4B1 mRNA	CTD	PMID:30012374
CYP4B1	Human	titanium dioxide	increases expression	ISO	RGD:10457	6480464	titanium dioxide results in increased expression of CYP4B1 mRNA	CTD	PMID:35295148
CYP4B1	Human	titanium dioxide	multiple interactions	ISO	RGD:10457	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP4B1 more ...	CTD	PMID:29950665
CYP4B1	Human	toluene	affects expression	ISO	RGD:2480	6480464	Toluene affects the expression of CYP4B1 mRNA	CTD	PMID:18653662
CYP4B1	Human	trichloroethene	decreases expression	ISO	RGD:2480	6480464	Trichloroethylene results in decreased expression of CYP4B1 mRNA	CTD	PMID:33387578
CYP4B1	Human	triclosan	increases expression	EXP		6480464	Triclosan results in increased expression of CYP4B1 mRNA	CTD	PMID:29849464
CYP4B1	Human	trimellitic anhydride	decreases expression	ISO	RGD:10457	6480464	trimellitic anhydride results in decreased expression of CYP4B1 mRNA	CTD	PMID:19042947
CYP4B1	Human	troglitazone	increases expression	ISO	RGD:2480	6480464	troglitazone results in increased expression of CYP4B1 mRNA	CTD	PMID:21515302
CYP4B1	Human	valproic acid	decreases methylation	EXP		6480464	Valproic Acid results in decreased methylation of CYP4B1 gene	CTD	PMID:29501571
CYP4B1	Human	valproic acid	decreases expression	ISO	RGD:2480	6480464	Valproic Acid results in decreased expression of CYP4B1 mRNA	CTD	PMID:35594946
CYP4B1	Human	vinclozolin	affects expression	ISO	RGD:2480	6480464	vinclozolin affects the expression of CYP4B1 mRNA	CTD	PMID:19015723
CYP4B1	Human	zinc atom	decreases expression	ISO	RGD:2480	6480464	Zinc deficiency results in decreased expression of CYP4B1 mRNA	CTD	PMID:12672911
CYP4B1	Human	zinc atom	increases expression	ISO	RGD:2480	6480464	Zinc deficiency results in increased expression of CYP4B1 mRNA; Zinc results in increased expression of more ...	CTD	PMID:11717422\|PMID:17074742
CYP4B1	Human	zinc sulfate	increases expression	ISO	RGD:2480	6480464	Zinc Sulfate results in increased expression of CYP4B1 mRNA	CTD	PMID:17074742
CYP4B1	Human	zinc(0)	decreases expression	ISO	RGD:2480	6480464	Zinc deficiency results in decreased expression of CYP4B1 mRNA	CTD	PMID:12672911
CYP4B1	Human	zinc(0)	increases expression	ISO	RGD:2480	6480464	Zinc deficiency results in increased expression of CYP4B1 mRNA; Zinc results in increased expression of more ...	CTD	PMID:11717422\|PMID:17074742
CYP4B1	Human	zoledronic acid	increases expression	EXP		6480464	zoledronic acid results in increased expression of CYP4B1 mRNA	CTD	PMID:24714768

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CYP4B1	Human	biphenyl metabolic process	involved_in	IEA	UniProtKB:P15129\|ensembl:ENSRNOP00000013321	150520179		Ensembl	GO_REF:0000107
CYP4B1	Human	biphenyl metabolic process		ISO	RGD:2480	9068941		RGD	PMID:9310344\|REF_RGD_ID:1626420
CYP4B1	Human	fatty acid metabolic process	involved_in	TAS		150520179		Reactome	Reactome:R-HSA-211935

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CYP4B1	Human	endoplasmic reticulum	located_in	IEA	UniProtKB-KW:KW-0256	150520179		UniProt	GO_REF:0000043
CYP4B1	Human	endoplasmic reticulum membrane	located_in	IEA	UniProtKB-SubCell:SL-0097	150520179		UniProt	GO_REF:0000044
CYP4B1	Human	endoplasmic reticulum membrane	located_in	TAS		150520179		Reactome	Reactome:R-HSA-211924
CYP4B1	Human	membrane	located_in	IEA	UniProtKB-KW:KW-0472	150520179		UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CYP4B1	Human	heme binding	enables	IEA	InterPro:IPR001128\|InterPro:IPR002401\|InterPro:IPR036396	150520179		InterPro	GO_REF:0000002
CYP4B1	Human	heterocyclic compound binding		ISO	CHEBI:173764	9068941		RGD	PMID:8248926\|REF_RGD_ID:1626415
CYP4B1	Human	heterocyclic compound binding	enables	IEA	UniProtKB:P15129\|ensembl:ENSRNOP00000013321	150520179		Ensembl	GO_REF:0000107
CYP4B1	Human	iron ion binding	enables	IEA	InterPro:IPR001128\|InterPro:IPR002401\|InterPro:IPR017972\|InterPro:IPR036396	150520179		InterPro	GO_REF:0000002
CYP4B1	Human	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
CYP4B1	Human	monooxygenase activity	enables	IEA	UniProtKB-KW:KW-0503	150520179		UniProt	GO_REF:0000043
CYP4B1	Human	monooxygenase activity	enables	IEA	ARBA:ARBA00028788	150520179		UniProt	GO_REF:0000117
CYP4B1	Human	monooxygenase activity	enables	TAS		150520179		Reactome	Reactome:R-HSA-211924
CYP4B1	Human	monooxygenase activity	enables	IEA	InterPro:IPR001128\|InterPro:IPR002401\|InterPro:IPR036396	150520179		InterPro	GO_REF:0000002
CYP4B1	Human	oxidoreductase activity	enables	IEA	UniProtKB-KW:KW-0560	150520179		UniProt	GO_REF:0000043
CYP4B1	Human	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	enables	IEA	InterPro:IPR001128\|InterPro:IPR002401\|InterPro:IPR017972\|InterPro:IPR036396	150520179		InterPro	GO_REF:0000002
CYP4B1	Human	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	enables	IEA	RHEA:17149	150520179		RHEA	GO_REF:0000116
CYP4B1	Human	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	enables	IEA	EC:1.14.14.1	150520179		UniProt	GO_REF:0000003
CYP4B1	Human	oxygen binding	enables	TAS		150520179	PMID:2574990	PINC	PMID:2574990

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CYP4B1	Human	phase I biotransformation pathway via cytochrome P450		ISO	RGD:2480	1626420		RGD
CYP4B1	Human	phase I biotransformation pathway via cytochrome P450		ISO	RGD:2480	1626415		RGD

#	Reference Title	Reference Citation
1.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
2.	Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4B1 in bladder mucosa.	Imaoka S, etal., Biochem Pharmacol. 1997 Sep 15;54(6):677-83.
3.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	CYP4B1 activates 4-ipomeanol in rat lung.	Verschoyle RD, etal., Toxicol Appl Pharmacol. 1993 Dec;123(2):193-8.

PMID:2298205	PMID:2574990	PMID:7894498	PMID:8125298	PMID:8313365	PMID:8694864	PMID:8889548	PMID:9202751	PMID:9364212	PMID:9493761	PMID:9498238	PMID:10768437
PMID:11062028	PMID:11669629	PMID:11737226	PMID:11767004	PMID:12142726	PMID:12477932	PMID:12837283	PMID:15006160	PMID:15028279	PMID:15128046	PMID:15499177	PMID:16344560
PMID:18660489	PMID:18713828	PMID:19040121	PMID:19074885	PMID:19343046	PMID:19898482	PMID:19913121	PMID:20379614	PMID:20628086	PMID:21873635	PMID:22675492	PMID:25247810
PMID:26252103	PMID:26355749	PMID:28514442	PMID:30803053	PMID:31801692	PMID:31862882	PMID:32054340	PMID:33592039	PMID:36307788	PMID:36768362	PMID:37950293	PMID:38041008

CYP4B1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	46,799,046 - 46,819,413 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	46,757,838 - 46,819,413 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	47,264,718 - 47,285,085 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	47,037,257 - 47,057,608 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	46,976,761 - 46,997,105	NCBI
Celera	1	45,552,027 - 45,572,396 (+)	NCBI		Celera
Cytogenetic Map	1	p33	NCBI
HuRef	1	45,380,284 - 45,400,633 (+)	NCBI		HuRef
CHM1_1	1	47,381,383 - 47,401,714 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI		T2T-CHM13v2.0

Cyp4b1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	115,481,895 - 115,504,918 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	115,481,922 - 115,504,920 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	115,624,698 - 115,647,721 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	115,624,725 - 115,647,723 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	115,297,333 - 115,320,310 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	115,122,660 - 115,145,637 (-)	NCBI		MGSCv36	mm8
Celera	4	114,360,727 - 114,383,719 (-)	NCBI		Celera
Cytogenetic Map	4	D1	NCBI
cM Map	4	53.06	NCBI

Cyp4b1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	134,375,807 - 134,413,635 (-)	NCBI		GRCr8
mRatBN7.2	5	129,139,019 - 129,176,860 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	129,139,038 - 129,156,348 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	131,749,529 - 131,766,903 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	133,504,409 - 133,521,783 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	133,526,563 - 133,543,937 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	134,508,728 - 134,526,103 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	134,508,730 - 134,526,089 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	138,299,551 - 138,316,860 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	135,917,327 - 135,934,636 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	135,922,552 - 135,939,862 (-)	NCBI
Celera	5	127,676,727 - 127,694,036 (-)	NCBI		Celera
RH 3.4 Map	5	823.3	RGD
Cytogenetic Map	5	q35	NCBI

LOC102012414
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955464	11,378,980 - 11,556,544 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955464	11,539,467 - 11,556,519 (-)	NCBI	ChiLan1.0	ChiLan1.0

CYP4B1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	179,984,908 - 180,003,684 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	179,126,616 - 179,145,387 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	46,107,787 - 46,127,162 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	47,462,178 - 47,481,502 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	47,462,178 - 47,481,502 (+)	Ensembl	panpan1.1		panPan2

CYP4B1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	13,676,631 - 13,694,483 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	13,676,371 - 13,694,705 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	13,796,940 - 13,814,798 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	13,826,980 - 13,844,834 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	13,826,737 - 13,844,877 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	13,628,060 - 13,645,902 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	13,696,377 - 13,714,240 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	13,765,891 - 13,783,754 (-)	NCBI		UU_Cfam_GSD_1.0

LOC101955242
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	61,881,092 - 61,957,546 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	27,767,371 - 27,782,008 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	27,705,874 - 27,782,328 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CYP4B1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	164,718,444 - 164,737,552 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	164,718,393 - 164,737,693 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	152,210,031 - 152,229,243 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CYP4B1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	85,997,796 - 86,018,649 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	85,996,269 - 86,018,055 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	30,987,875 - 31,007,108 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101725929
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624906	2,663,940 - 2,684,171 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624906	2,664,057 - 2,683,527 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in CYP4B1
66 total Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 1p34.3-33(chr1:39479787-47688131)x3	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051817]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051817]\|See cases [RCV000051817]	Chr1:39479787..47688131 [GRCh38] Chr1:39945459..48153803 [GRCh37] Chr1:39718046..47926390 [NCBI36] Chr1:1p34.3-33	pathogenic
NM_000779.3(CYP4B1):c.1293C>T (p.Ser431=)	single nucleotide variant	Malignant melanoma [RCV000060202]	Chr1:46818154 [GRCh38] Chr1:47283826 [GRCh37] Chr1:47056413 [NCBI36] Chr1:1p33	not provided
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3	copy number loss	not provided [RCV000762767]	Chr1:20608823..120546301 [GRCh37] Chr1:1p36.12-12	likely benign
GRCh37/hg19 1p34.1-33(chr1:46747177-47280720)x3	copy number gain	See cases [RCV000449344]	Chr1:46747177..47280720 [GRCh37] Chr1:1p34.1-33	uncertain significance
GRCh37/hg19 1p34.1-32.3(chr1:45303358-52157856)x1	copy number loss	See cases [RCV000448358]	Chr1:45303358..52157856 [GRCh37] Chr1:1p34.1-32.3	likely pathogenic
NM_001099772.2(CYP4B1):c.884_885del (p.Asp295fs)	deletion	not specified [RCV000455155]	Chr1:46815075..46815076 [GRCh38] Chr1:47280747..47280748 [GRCh37] Chr1:1p33	benign
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3	copy number gain	See cases [RCV000510383]	Chr1:849467..249224684 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)	copy number gain	See cases [RCV000510926]	Chr1:849467..249224684 [GRCh37] Chr1:1p36.33-q44	pathogenic
NM_001099772.2(CYP4B1):c.1481G>A (p.Arg494His)	single nucleotide variant	not specified [RCV004282193]	Chr1:46818756 [GRCh38] Chr1:47284428 [GRCh37] Chr1:1p33	uncertain significance
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3	copy number gain	not provided [RCV000736295]	Chr1:47851..249228449 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3	copy number gain	not provided [RCV000736305]	Chr1:82154..249218992 [GRCh37] Chr1:1p36.33-q44	pathogenic
NM_001099772.2(CYP4B1):c.804C>G (p.Ala268=)	single nucleotide variant	not provided [RCV000916640]	Chr1:46814237 [GRCh38] Chr1:47279909 [GRCh37] Chr1:1p33	likely benign
GRCh37/hg19 1p36.22-21.1(chr1:103343285-103455144)x3	copy number gain	Global developmental delay [RCV000787285]	Chr1:103343285..103455144 [GRCh37] Chr1:1p36.22-21.1	uncertain significance
NM_001099772.2(CYP4B1):c.1109G>C (p.Cys370Ser)	single nucleotide variant	not provided [RCV000883651]	Chr1:46817083 [GRCh38] Chr1:47282755 [GRCh37] Chr1:1p33	benign
NM_001099772.2(CYP4B1):c.1333A>G (p.Met445Val)	single nucleotide variant	not specified [RCV004301656]	Chr1:46818191 [GRCh38] Chr1:47283863 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.793C>T (p.Arg265Trp)	single nucleotide variant	not provided [RCV000963757]	Chr1:46814226 [GRCh38] Chr1:47279898 [GRCh37] Chr1:1p33	benign
NM_001099772.2(CYP4B1):c.739T>C (p.Phe247Leu)	single nucleotide variant	not provided [RCV000908843]	Chr1:46814027 [GRCh38] Chr1:47279699 [GRCh37] Chr1:1p33	likely benign
NM_001099772.2(CYP4B1):c.1208-10C>T	single nucleotide variant	not provided [RCV000899754]	Chr1:46817955 [GRCh38] Chr1:47283627 [GRCh37] Chr1:1p33	benign
NM_001099772.2(CYP4B1):c.147T>C (p.Pro49=)	single nucleotide variant	not provided [RCV000954367]	Chr1:46799228 [GRCh38] Chr1:47264900 [GRCh37] Chr1:1p33	benign\|likely benign
GRCh37/hg19 1p33-32.3(chr1:47272184-52505405)x1	copy number loss	not provided [RCV001005086]	Chr1:47272184..52505405 [GRCh37] Chr1:1p33-32.3	pathogenic
NM_001099772.2(CYP4B1):c.1054G>A (p.Asp352Asn)	single nucleotide variant	not specified [RCV004331863]	Chr1:46815245 [GRCh38] Chr1:47280917 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.484C>T (p.Arg162Cys)	single nucleotide variant	not specified [RCV004291701]	Chr1:46812612 [GRCh38] Chr1:47278284 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1448G>A (p.Arg483Gln)	single nucleotide variant	not provided [RCV000961882]	Chr1:46818723 [GRCh38] Chr1:47284395 [GRCh37] Chr1:1p33	benign
NM_001099772.2(CYP4B1):c.849C>T (p.His283=)	single nucleotide variant	not provided [RCV000969981]	Chr1:46814282 [GRCh38] Chr1:47279954 [GRCh37] Chr1:1p33	benign\|likely benign
NM_001099772.2(CYP4B1):c.989A>C (p.Tyr330Ser)	single nucleotide variant	not provided [RCV000974839]	Chr1:46815180 [GRCh38] Chr1:47280852 [GRCh37] Chr1:1p33	benign
NM_001099772.2(CYP4B1):c.1064T>G (p.Phe355Cys)	single nucleotide variant	not provided [RCV000974840]	Chr1:46815255 [GRCh38] Chr1:47280927 [GRCh37] Chr1:1p33	benign
NM_001099772.2(CYP4B1):c.13T>A (p.Phe5Ile)	single nucleotide variant	not provided [RCV000901930]	Chr1:46799094 [GRCh38] Chr1:47264766 [GRCh37] Chr1:1p33	benign
NM_001099772.2(CYP4B1):c.330G>A (p.Lys110=)	single nucleotide variant	not provided [RCV000955714]	Chr1:46811147 [GRCh38] Chr1:47276819 [GRCh37] Chr1:1p33	benign
NM_001099772.2(CYP4B1):c.971G>T (p.Gly324Val)	single nucleotide variant	not specified [RCV004608567]	Chr1:46815162 [GRCh38] Chr1:47280834 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1036G>A (p.Val346Ile)	single nucleotide variant	not specified [RCV004608564]	Chr1:46815227 [GRCh38] Chr1:47280899 [GRCh37] Chr1:1p33	likely benign
NM_001099772.2(CYP4B1):c.191C>T (p.Thr64Met)	single nucleotide variant	not specified [RCV004608565]	Chr1:46810818 [GRCh38] Chr1:47276490 [GRCh37] Chr1:1p33	uncertain significance
GRCh37/hg19 1p34.1-32.3(chr1:45303358-52157856)	copy number loss	not specified [RCV002053281]	Chr1:45303358..52157856 [GRCh37] Chr1:1p34.1-32.3	likely pathogenic
GRCh37/hg19 1p35.1-33(chr1:33285582-47891811)	copy number gain	not specified [RCV002052781]	Chr1:33285582..47891811 [GRCh37] Chr1:1p35.1-33	pathogenic
NM_001099772.2(CYP4B1):c.170A>G (p.His57Arg)	single nucleotide variant	not specified [RCV004608568]	Chr1:46799251 [GRCh38] Chr1:47264923 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1441C>G (p.Pro481Ala)	single nucleotide variant	not specified [RCV004608569]	Chr1:46818716 [GRCh38] Chr1:47284388 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.127A>C (p.Met43Leu)	single nucleotide variant	not specified [RCV004150839]	Chr1:46799208 [GRCh38] Chr1:47264880 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1039C>T (p.Arg347Cys)	single nucleotide variant	not specified [RCV004205619]	Chr1:46815230 [GRCh38] Chr1:47280902 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.316C>T (p.Arg106Cys)	single nucleotide variant	not specified [RCV004203336]	Chr1:46810943 [GRCh38] Chr1:47276615 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.506A>G (p.Glu169Gly)	single nucleotide variant	not specified [RCV004226351]	Chr1:46813492 [GRCh38] Chr1:47279164 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1361G>A (p.Cys454Tyr)	single nucleotide variant	not specified [RCV004077163]	Chr1:46818636 [GRCh38] Chr1:47284308 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.841C>T (p.Arg281Trp)	single nucleotide variant	not specified [RCV004208849]	Chr1:46814274 [GRCh38] Chr1:47279946 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.*437T>C	single nucleotide variant	Pulmonary disease, chronic obstructive, susceptibility to [RCV002508849]	Chr1:46819251 [GRCh38] Chr1:47284923 [GRCh37] Chr1:1p33	association
NM_001099772.2(CYP4B1):c.845G>C (p.Arg282Thr)	single nucleotide variant	not specified [RCV004224694]	Chr1:46814278 [GRCh38] Chr1:47279950 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.43C>A (p.Leu15Met)	single nucleotide variant	not specified [RCV004120683]	Chr1:46799124 [GRCh38] Chr1:47264796 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.842G>A (p.Arg281Gln)	single nucleotide variant	not specified [RCV004225862]	Chr1:46814275 [GRCh38] Chr1:47279947 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1018C>G (p.His340Asp)	single nucleotide variant	not specified [RCV004129850]	Chr1:46815209 [GRCh38] Chr1:47280881 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1300G>A (p.Glu434Lys)	single nucleotide variant	not specified [RCV004270262]	Chr1:46818158 [GRCh38] Chr1:47283830 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.256G>A (p.Gly86Arg)	single nucleotide variant	not specified [RCV004249229]	Chr1:46810883 [GRCh38] Chr1:47276555 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1057C>A (p.Gln353Lys)	single nucleotide variant	not specified [RCV004268343]	Chr1:46815248 [GRCh38] Chr1:47280920 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1348G>A (p.Gly450Arg)	single nucleotide variant	not specified [RCV004249480]	Chr1:46818206 [GRCh38] Chr1:47283878 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1364T>G (p.Ile455Ser)	single nucleotide variant	not specified [RCV004365769]	Chr1:46818639 [GRCh38] Chr1:47284311 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1040G>A (p.Arg347His)	single nucleotide variant	not specified [RCV004345077]	Chr1:46815231 [GRCh38] Chr1:47280903 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.203A>G (p.Asp68Gly)	single nucleotide variant	not specified [RCV004346659]	Chr1:46810830 [GRCh38] Chr1:47276502 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.254T>C (p.Phe85Ser)	single nucleotide variant	not specified [RCV004364148]	Chr1:46810881 [GRCh38] Chr1:47276553 [GRCh37] Chr1:1p33	uncertain significance
Single allele	inversion	Bilateral polymicrogyria [RCV003459046]	Chr1:33246132..61045156 [GRCh38] Chr1:1p35.1-31.3	likely pathogenic
NM_001099772.2(CYP4B1):c.413G>A (p.Arg138His)	single nucleotide variant	not specified [RCV004370520]	Chr1:46812541 [GRCh38] Chr1:47278213 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1420C>T (p.Arg474Cys)	single nucleotide variant	not specified [RCV004370516]	Chr1:46818695 [GRCh38] Chr1:47284367 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1253C>A (p.Ala418Asp)	single nucleotide variant	not specified [RCV004370515]	Chr1:46818010 [GRCh38] Chr1:47283682 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.734G>A (p.Arg245His)	single nucleotide variant	not specified [RCV004370525]	Chr1:46814022 [GRCh38] Chr1:47279694 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.458A>T (p.Tyr153Phe)	single nucleotide variant	not specified [RCV004370522]	Chr1:46812586 [GRCh38] Chr1:47278258 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.287A>G (p.Glu96Gly)	single nucleotide variant	not specified [RCV004370518]	Chr1:46810914 [GRCh38] Chr1:47276586 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1201C>G (p.Pro401Ala)	single nucleotide variant	not specified [RCV004370514]	Chr1:46817175 [GRCh38] Chr1:47282847 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.1441C>T (p.Pro481Ser)	single nucleotide variant	not specified [RCV004370517]	Chr1:46818716 [GRCh38] Chr1:47284388 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.733C>T (p.Arg245Cys)	single nucleotide variant	not specified [RCV004370524]	Chr1:46814021 [GRCh38] Chr1:47279693 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.341T>C (p.Val114Ala)	single nucleotide variant	not specified [RCV004370519]	Chr1:46811158 [GRCh38] Chr1:47276830 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.530C>A (p.Ser177Tyr)	single nucleotide variant	not specified [RCV004370523]	Chr1:46813516 [GRCh38] Chr1:47279188 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.994A>G (p.Met332Val)	single nucleotide variant	not specified [RCV004913384]	Chr1:46815185 [GRCh38] Chr1:47280857 [GRCh37] Chr1:1p33	uncertain significance
GRCh37/hg19 1p34.1-22.2(chr1:44475302-89585894)x3	copy number gain	not provided [RCV004819297]	Chr1:44475302..89585894 [GRCh37] Chr1:1p34.1-22.2	pathogenic
NM_001099772.2(CYP4B1):c.7C>A (p.Pro3Thr)	single nucleotide variant	not specified [RCV004913380]	Chr1:46799088 [GRCh38] Chr1:47264760 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.776A>G (p.Asp259Gly)	single nucleotide variant	not specified [RCV004913381]	Chr1:46814209 [GRCh38] Chr1:47279881 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.262T>C (p.Phe88Leu)	single nucleotide variant	not specified [RCV004913383]	Chr1:46810889 [GRCh38] Chr1:47276561 [GRCh37] Chr1:1p33	uncertain significance
NM_001099772.2(CYP4B1):c.74G>A (p.Gly25Asp)	single nucleotide variant	not specified [RCV004913382]	Chr1:46799155 [GRCh38] Chr1:47264827 [GRCh37] Chr1:1p33	uncertain significance

Predicted Target Of

	Summary Value
Count of predictions:	3951
Count of miRNA genes:	1027
Interacting mature miRNAs:	1263
Transcripts:	ENST00000271153, ENST00000371919, ENST00000371923, ENST00000413093, ENST00000452782, ENST00000464439, ENST00000468637, ENST00000481248, ENST00000497005, ENST00000526297, ENST00000529715, ENST00000534708, ENST00000546128
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
597316346	GWAS1412420_H	X-21258 measurement QTL GWAS1412420 (human)		6e-22	X-21258 measurement		1	46816108	46816109	Human
2314561	GLUCO47_H	Glucose level QTL 47 (human)	1.1		Glucose level		1	44773360	70773360	Human
597282778	GWAS1378852_H	COVID-19 QTL GWAS1378852 (human)		1e-08	COVID-19		1	46811056	46811057	Human
407027368	GWAS676344_H	testosterone measurement QTL GWAS676344 (human)		0.000008	testosterone measurement	serum testosterone level (CMO:0000568)	1	46819251	46819252	Human
597234068	GWAS1330142_H	abdominal fat cell number QTL GWAS1330142 (human)		0.000003	abdominal fat cell number		1	46799757	46799758	Human
407047629	GWAS696605_H	serum metabolite measurement QTL GWAS696605 (human)		4e-12	serum metabolite measurement		1	46816155	46816156	Human
597138648	GWAS1234722_H	10-undecenoate 11:1n1 measurement QTL GWAS1234722 (human)		5e-22	10-undecenoate 11:1n1 measurement		1	46813167	46813168	Human
597136391	GWAS1232465_H	X-24748 measurement QTL GWAS1232465 (human)		8e-17	X-24748 measurement		1	46817833	46817834	Human
597188044	GWAS1284118_H	glycine conjugate of C10H12O2 measurement QTL GWAS1284118 (human)		2e-10	glycine conjugate of C10H12O2 measurement		1	46809569	46809570	Human
597162467	GWAS1258541_H	peptide measurement QTL GWAS1258541 (human)		0.0000001	peptide metabolism trait (VT:0010634)		1	46818854	46818855	Human
596951778	GWAS1071297_H	COVID-19 QTL GWAS1071297 (human)		1e-08	COVID-19		1	46811056	46811057	Human
597141006	GWAS1237080_H	X-18899 measurement QTL GWAS1237080 (human)		2e-11	X-18899 measurement		1	46800750	46800751	Human
597264928	GWAS1361002_H	10-undecenoate 11:1n1 measurement QTL GWAS1361002 (human)		9e-12	10-undecenoate 11:1n1 measurement		1	46815630	46815631	Human
597141514	GWAS1237588_H	undecenoylcarnitine (C11:1) measurement QTL GWAS1237588 (human)		2e-21	undecenoylcarnitine (C11:1) measurement		1	46810570	46810571	Human

CYP4B1_1569

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	47,284,368 - 47,285,027	UniSTS	GRCh37
Build 36	1	47,056,955 - 47,057,614	RGD	NCBI36
Celera	1	45,571,743 - 45,572,402	RGD
HuRef	1	45,399,980 - 45,400,639	UniSTS

D1S3695

Human Assembly	Chr	Position (strand)	Source
Cytogenetic Map	X	q22.3	UniSTS
Cytogenetic Map	7	q34	UniSTS
Cytogenetic Map	19	q13.43	UniSTS
Cytogenetic Map	15	q23	UniSTS
Cytogenetic Map	22	q12.2	UniSTS
Cytogenetic Map	1	p12	UniSTS
Cytogenetic Map	12	q12	UniSTS
Cytogenetic Map	6	p21	UniSTS
Cytogenetic Map	11	p13	UniSTS
Cytogenetic Map	11	q12.3	UniSTS
Cytogenetic Map	15	q22.31	UniSTS
Cytogenetic Map	14	q23.1	UniSTS
Cytogenetic Map	1	p34-p12	UniSTS
Cytogenetic Map	6	q27	UniSTS

D1S3259

Human Assembly	Chr	Position (strand)	Source
Cytogenetic Map	1	p34-p12	UniSTS
GeneMap99-GB4 RH Map	1	145.5	UniSTS
GeneMap99-G3 RH Map	1	2378.0	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
1204	2392	2788	2227	4741	1556	2100	5	461	1404	301	2136	6518	5922	21	3625	1	804	1704	1532	172	1


RefSeq Transcripts	NG_007939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_000779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001099772	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001319161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001319162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001319163	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_135003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_178057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_178058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_178059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_178060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_178061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_946559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF491285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK225576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK225578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK300921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK300941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK307715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK313170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL356793	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL593856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY064484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY064485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY064486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY151048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY151049	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC017758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BM977596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BM982575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CD013981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA380788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DC358497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ518907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	J02871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X16699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000271153 ⟹ ENSP00000271153

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,799,046 - 46,819,413 (+)	Ensembl

Ensembl Acc Id:

ENST00000371919 ⟹ ENSP00000360987

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,799,082 - 46,818,814 (+)	Ensembl

Ensembl Acc Id:

ENST00000371923 ⟹ ENSP00000360991

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,799,046 - 46,819,413 (+)	Ensembl

Ensembl Acc Id:

ENST00000413093

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,757,878 - 46,790,499 (+)	Ensembl

Ensembl Acc Id:

ENST00000452782

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,811,073 - 46,818,842 (+)	Ensembl

Ensembl Acc Id:

ENST00000464439 ⟹ ENSP00000433068

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,799,064 - 46,819,349 (+)	Ensembl

Ensembl Acc Id:

ENST00000468637

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,811,103 - 46,817,181 (+)	Ensembl

Ensembl Acc Id:

ENST00000481248

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,815,074 - 46,817,357 (+)	Ensembl

Ensembl Acc Id:

ENST00000497005

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,817,048 - 46,819,015 (+)	Ensembl

Ensembl Acc Id:

ENST00000526297 ⟹ ENSP00000438995

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,806,807 - 46,813,988 (+)	Ensembl

Ensembl Acc Id:

ENST00000529715 ⟹ ENSP00000443212

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,799,051 - 46,815,411 (+)	Ensembl

Ensembl Acc Id:

ENST00000534708 ⟹ ENSP00000433367

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,798,998 - 46,818,670 (+)	Ensembl

Ensembl Acc Id:

ENST00000546128

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,757,838 - 46,810,850 (+)	Ensembl

Ensembl Acc Id:

ENST00000614163 ⟹ ENSP00000484629

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,799,082 - 46,818,814 (+)	Ensembl

Ensembl Acc Id:

ENST00000640628 ⟹ ENSP00000492115

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	46,798,998 - 46,814,759 (+)	Ensembl

RefSeq Acc Id:

NM_000779 ⟹ NP_000770

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	46,799,046 - 46,819,413 (+)	NCBI
GRCh37	1	47,264,670 - 47,285,021 (+)	ENTREZGENE
GRCh37	1	47,264,670 - 47,285,021 (+)	NCBI
Build 36	1	47,037,257 - 47,057,608 (+)	NCBI Archive
HuRef	1	45,380,284 - 45,400,633 (+)	ENTREZGENE
CHM1_1	1	47,381,383 - 47,401,714 (+)	NCBI
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

Sequence:

show sequence

AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCA
CCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAGATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGG
CCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGCTTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGACCCTAAGGCCCCTGATGTGTATGAC
TTCTTCCTCCAGTGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGA
GTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACA
CCGGCCTGGGCCACAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGC
CGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGA
CATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACT
GCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAG
AGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGGAAGCCTGATCTCTATGCATATCTATGCCCTCCATAGGAA
CAGTGCTGTATGGCCCGACCCTGAGGTCTTTGACTCTCTGCGCTTTTCCACTGAGAATGCATCCAAACGCCATCCCTTTGCCTTTATGCCCTTCTCTGCTGGGCCCAGGAACTGCATTGGGCAGCAGT
TTGCCATGAGTGAGATGAAGGTGGTCACAGCCATGTGCTTGCTCCGCTTTGAGTTCTCTCTGGACCCCTCACGGCTGCCCATCAAGATGCCCCAGCTTGTCCTGCGCTCCAAGAATGGCTTTCACCTC
CACCTGAAGCCACTGGGCCCTGGGTCTGGGAAGTAGCTCTGATGAGAATGGGGTCCCAGATGGCTCAGGCTGTGACCTCCCTGGGCACCACCCTCCCCAGGCTGGGTGTGGAGGAGTTGGGGCCCCCT
GCCTTCAGGAGGCTTGTAGTTTAGAAGGGAAGTAGGCATTACCATAGACGACTCCTAGAGGACAGTGCTATGTAAAAATGTGTGTCTATAAATGTTTATCATGCATGTATTCTAGAGCTCATTCATTT
ATTCAACAAACATTTGGTGAGCACCTATTTCGTTCGAGAAACTTCATTTATCTCCTATAATTGGCAAACTTAAAAATGCAGCAGAAACTTACATTCCAACCTTAGAGACTCATAGTGAGCACAAGGAA
AGTTTTGCCCTGAGATTCATGGTTATGGCTGGGTACCACCAAATAGAAGAATGGCTTAGGGGAGTGCCCCTTCACTGAGATGTGTTTCTTTGTTGAACTTTGTGTGTGTGTGTTTAGAATATAACAGA
CATAAGAAAAAATTACCTAAATGAAGACTGTACAAAATAATAAATAATTCTGAAGCAGACTCTCTTGTAACCATCACTGAAGTCAAGAAATATGGAATATGGTATCACTGATGTGTCTTCTGC

hide sequence

RefSeq Acc Id:

NM_001099772 ⟹ NP_001093242

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	46,799,046 - 46,819,413 (+)	NCBI
GRCh37	1	47,264,670 - 47,285,021 (+)	ENTREZGENE
GRCh37	1	47,264,670 - 47,285,021 (+)	NCBI
Build 36	1	47,037,257 - 47,057,608 (+)	NCBI Archive
HuRef	1	45,380,284 - 45,400,633 (+)	ENTREZGENE
CHM1_1	1	47,381,383 - 47,401,714 (+)	NCBI
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

Sequence:

show sequence

AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCA
CCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAGATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGG
CCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGCTTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGACCCTAAGGCCCCTGATGTGTATGAC
TTCTTCCTCCAGTGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGA
GTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACA
CCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGC
CGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCT
GGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCT
ACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAG
GAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGGAAGCCTGATCTCTATGCATATCTATGCCCTCCATAG
GAACAGTGCTGTATGGCCCGACCCTGAGGTCTTTGACTCTCTGCGCTTTTCCACTGAGAATGCATCCAAACGCCATCCCTTTGCCTTTATGCCCTTCTCTGCTGGGCCCAGGAACTGCATTGGGCAGC
AGTTTGCCATGAGTGAGATGAAGGTGGTCACAGCCATGTGCTTGCTCCGCTTTGAGTTCTCTCTGGACCCCTCACGGCTGCCCATCAAGATGCCCCAGCTTGTCCTGCGCTCCAAGAATGGCTTTCAC
CTCCACCTGAAGCCACTGGGCCCTGGGTCTGGGAAGTAGCTCTGATGAGAATGGGGTCCCAGATGGCTCAGGCTGTGACCTCCCTGGGCACCACCCTCCCCAGGCTGGGTGTGGAGGAGTTGGGGCCC
CCTGCCTTCAGGAGGCTTGTAGTTTAGAAGGGAAGTAGGCATTACCATAGACGACTCCTAGAGGACAGTGCTATGTAAAAATGTGTGTCTATAAATGTTTATCATGCATGTATTCTAGAGCTCATTCA
TTTATTCAACAAACATTTGGTGAGCACCTATTTCGTTCGAGAAACTTCATTTATCTCCTATAATTGGCAAACTTAAAAATGCAGCAGAAACTTACATTCCAACCTTAGAGACTCATAGTGAGCACAAG
GAAAGTTTTGCCCTGAGATTCATGGTTATGGCTGGGTACCACCAAATAGAAGAATGGCTTAGGGGAGTGCCCCTTCACTGAGATGTGTTTCTTTGTTGAACTTTGTGTGTGTGTGTTTAGAATATAAC
AGACATAAGAAAAAATTACCTAAATGAAGACTGTACAAAATAATAAATAATTCTGAAGCAGACTCTCTTGTAACCATCACTGAAGTCAAGAAATATGGAATATGGTATCACTGATGTGTCTTCTGC

hide sequence

RefSeq Acc Id:

NM_001319161 ⟹ NP_001306090

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	46,799,046 - 46,819,413 (+)	NCBI
CHM1_1	1	47,381,383 - 47,401,714 (+)	NCBI
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

Sequence:

show sequence

AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCA
CCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAGATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGG
CCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGCTTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGGGAGAGGCCTGCTGGTTCTTGAGGGG
CCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGA
GGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCA
GCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGAC
CAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTC
AGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGG
AGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAG
CTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGGAAGCCTGATCTCTATGCATATCTATGCCCTCCATAGGAACAGTGCTGTATGGCCCGACCCTGAGGTCTTTGACTCTCTGCG
CTTTTCCACTGAGAATGCATCCAAACGCCATCCCTTTGCCTTTATGCCCTTCTCTGCTGGGCCCAGGAACTGCATTGGGCAGCAGTTTGCCATGAGTGAGATGAAGGTGGTCACAGCCATGTGCTTGC
TCCGCTTTGAGTTCTCTCTGGACCCCTCACGGCTGCCCATCAAGATGCCCCAGCTTGTCCTGCGCTCCAAGAATGGCTTTCACCTCCACCTGAAGCCACTGGGCCCTGGGTCTGGGAAGTAGCTCTGA
TGAGAATGGGGTCCCAGATGGCTCAGGCTGTGACCTCCCTGGGCACCACCCTCCCCAGGCTGGGTGTGGAGGAGTTGGGGCCCCCTGCCTTCAGGAGGCTTGTAGTTTAGAAGGGAAGTAGGCATTAC
CATAGACGACTCCTAGAGGACAGTGCTATGTAAAAATGTGTGTCTATAAATGTTTATCATGCATGTATTCTAGAGCTCATTCATTTATTCAACAAACATTTGGTGAGCACCTATTTCGTTCGAGAAAC
TTCATTTATCTCCTATAATTGGCAAACTTAAAAATGCAGCAGAAACTTACATTCCAACCTTAGAGACTCATAGTGAGCACAAGGAAAGTTTTGCCCTGAGATTCATGGTTATGGCTGGGTACCACCAA
ATAGAAGAATGGCTTAGGGGAGTGCCCCTTCACTGAGATGTGTTTCTTTGTTGAACTTTGTGTGTGTGTGTTTAGAATATAACAGACATAAGAAAAAATTACCTAAATGAAGACTGTACAAAATAATA
AATAATTCTGAAGCAGACTCTCTTGTAACCATCACTGAAGTCAAGAAATATGGAATATGGTATCACTGATGTGTCTTCTGC

hide sequence

RefSeq Acc Id:

NM_001319162 ⟹ NP_001306091

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	46,799,046 - 46,819,413 (+)	NCBI
CHM1_1	1	47,381,383 - 47,401,714 (+)	NCBI
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

Sequence:

show sequence

AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCA
CCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCA
GCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTG
ACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTG
TTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGA
GCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCC
GGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATC
CTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGT
CACCTTTGTGGATGGCCGGTCTCTACCTGCAGGAAGCCTGATCTCTATGCATATCTATGCCCTCCATAGGAACAGTGCTGTATGGCCCGACCCTGAGGTCTTTGACTCTCTGCGCTTTTCCACTGAGA
ATGCATCCAAACGCCATCCCTTTGCCTTTATGCCCTTCTCTGCTGGGCCCAGGAACTGCATTGGGCAGCAGTTTGCCATGAGTGAGATGAAGGTGGTCACAGCCATGTGCTTGCTCCGCTTTGAGTTC
TCTCTGGACCCCTCACGGCTGCCCATCAAGATGCCCCAGCTTGTCCTGCGCTCCAAGAATGGCTTTCACCTCCACCTGAAGCCACTGGGCCCTGGGTCTGGGAAGTAGCTCTGATGAGAATGGGGTCC
CAGATGGCTCAGGCTGTGACCTCCCTGGGCACCACCCTCCCCAGGCTGGGTGTGGAGGAGTTGGGGCCCCCTGCCTTCAGGAGGCTTGTAGTTTAGAAGGGAAGTAGGCATTACCATAGACGACTCCT
AGAGGACAGTGCTATGTAAAAATGTGTGTCTATAAATGTTTATCATGCATGTATTCTAGAGCTCATTCATTTATTCAACAAACATTTGGTGAGCACCTATTTCGTTCGAGAAACTTCATTTATCTCCT
ATAATTGGCAAACTTAAAAATGCAGCAGAAACTTACATTCCAACCTTAGAGACTCATAGTGAGCACAAGGAAAGTTTTGCCCTGAGATTCATGGTTATGGCTGGGTACCACCAAATAGAAGAATGGCT
TAGGGGAGTGCCCCTTCACTGAGATGTGTTTCTTTGTTGAACTTTGTGTGTGTGTGTTTAGAATATAACAGACATAAGAAAAAATTACCTAAATGAAGACTGTACAAAATAATAAATAATTCTGAAGC
AGACTCTCTTGTAACCATCACTGAAGTCAAGAAATATGGAATATGGTATCACTGATGTGTCTTCTGC

hide sequence

RefSeq Acc Id:

NM_001319163 ⟹ NP_001306092

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	46,799,046 - 46,819,413 (+)	NCBI
CHM1_1	1	47,381,383 - 47,401,714 (+)	NCBI
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

Sequence:

show sequence

AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCA
CCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCA
GCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTG
ACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTG
ATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCG
GAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGG
CTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTA
GGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCAC
CTTTGTGGATGGCCGGTCTCTACCTGCAGGAAGCCTGATCTCTATGCATATCTATGCCCTCCATAGGAACAGTGCTGTATGGCCCGACCCTGAGGTCTTTGACTCTCTGCGCTTTTCCACTGAGAATG
CATCCAAACGCCATCCCTTTGCCTTTATGCCCTTCTCTGCTGGGCCCAGGAACTGCATTGGGCAGCAGTTTGCCATGAGTGAGATGAAGGTGGTCACAGCCATGTGCTTGCTCCGCTTTGAGTTCTCT
CTGGACCCCTCACGGCTGCCCATCAAGATGCCCCAGCTTGTCCTGCGCTCCAAGAATGGCTTTCACCTCCACCTGAAGCCACTGGGCCCTGGGTCTGGGAAGTAGCTCTGATGAGAATGGGGTCCCAG
ATGGCTCAGGCTGTGACCTCCCTGGGCACCACCCTCCCCAGGCTGGGTGTGGAGGAGTTGGGGCCCCCTGCCTTCAGGAGGCTTGTAGTTTAGAAGGGAAGTAGGCATTACCATAGACGACTCCTAGA
GGACAGTGCTATGTAAAAATGTGTGTCTATAAATGTTTATCATGCATGTATTCTAGAGCTCATTCATTTATTCAACAAACATTTGGTGAGCACCTATTTCGTTCGAGAAACTTCATTTATCTCCTATA
ATTGGCAAACTTAAAAATGCAGCAGAAACTTACATTCCAACCTTAGAGACTCATAGTGAGCACAAGGAAAGTTTTGCCCTGAGATTCATGGTTATGGCTGGGTACCACCAAATAGAAGAATGGCTTAG
GGGAGTGCCCCTTCACTGAGATGTGTTTCTTTGTTGAACTTTGTGTGTGTGTGTTTAGAATATAACAGACATAAGAAAAAATTACCTAAATGAAGACTGTACAAAATAATAAATAATTCTGAAGCAGA
CTCTCTTGTAACCATCACTGAAGTCAAGAAATATGGAATATGGTATCACTGATGTGTCTTCTGC

hide sequence

RefSeq Acc Id:

NR_135003

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	46,799,046 - 46,819,413 (+)	NCBI
CHM1_1	1	47,381,383 - 47,401,714 (+)	NCBI
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

Sequence:

show sequence

AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCT
TCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCAC
TGGCTTTTTGGACATGCCCTCGAGATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGCTTCCTGAACATCTA
TGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGACCCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAGTGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACC
GCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATC
TTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTC
CTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCT
CCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGG
CCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTC
CGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGGAAGCCTGATCTCTATGCATATCTATGCCCTCCATAGGAACAGTGC
TGTATGGCCCGACCCTGAGGTCTTTGACTCTCTGCGCTTTTCCACTGAGAATGCATCCAAACGCCATCCCTTTGCCTTTATGCCCTTCTCTGCTGGGCCCAGGAACTGCATTGGGCAGCAGTTTGCCA
TGAGTGAGATGAAGGTGGTCACAGCCATGTGCTTGCTCCGCTTTGAGTTCTCTCTGGACCCCTCACGGCTGCCCATCAAGATGCCCCAGCTTGTCCTGCGCTCCAAGAATGGCTTTCACCTCCACCTG
AAGCCACTGGGCCCTGGGTCTGGGAAGTAGCTCTGATGAGAATGGGGTCCCAGATGGCTCAGGCTGTGACCTCCCTGGGCACCACCCTCCCCAGGCTGGGTGTGGAGGAGTTGGGGCCCCCTGCCTTC
AGGAGGCTTGTAGTTTAGAAGGGAAGTAGGCATTACCATAGACGACTCCTAGAGGACAGTGCTATGTAAAAATGTGTGTCTATAAATGTTTATCATGCATGTATTCTAGAGCTCATTCATTTATTCAA
CAAACATTTGGTGAGCACCTATTTCGTTCGAGAAACTTCATTTATCTCCTATAATTGGCAAACTTAAAAATGCAGCAGAAACTTACATTCCAACCTTAGAGACTCATAGTGAGCACAAGGAAAGTTTT
GCCCTGAGATTCATGGTTATGGCTGGGTACCACCAAATAGAAGAATGGCTTAGGGGAGTGCCCCTTCACTGAGATGTGTTTCTTTGTTGAACTTTGTGTGTGTGTGTTTAGAATATAACAGACATAAG
AAAAAATTACCTAAATGAAGACTGTACAAAATAATAAATAATTCTGAAGCAGACTCTCTTGTAACCATCACTGAAGTCAAGAAATATGGAATATGGTATCACTGATGTGTCTTCTGC

hide sequence

RefSeq Acc Id:

NR_178057

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

RefSeq Acc Id:

NR_178058

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

RefSeq Acc Id:

NR_178059

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

RefSeq Acc Id:

NR_178060

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI

RefSeq Acc Id:

NR_178061

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	1	46,676,425 - 46,696,812 (+)	NCBI


Protein RefSeqs	NP_000770	(Get FASTA)	NCBI Sequence Viewer
	NP_001093242	(Get FASTA)	NCBI Sequence Viewer
	NP_001306090	(Get FASTA)	NCBI Sequence Viewer
	NP_001306091	(Get FASTA)	NCBI Sequence Viewer
	NP_001306092	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA35712	(Get FASTA)	NCBI Sequence Viewer
	AAH17758	(Get FASTA)	NCBI Sequence Viewer
	AAL57719	(Get FASTA)	NCBI Sequence Viewer
	AAL57720	(Get FASTA)	NCBI Sequence Viewer
	AAL57721	(Get FASTA)	NCBI Sequence Viewer
	AAM09532	(Get FASTA)	NCBI Sequence Viewer
	AAN72311	(Get FASTA)	NCBI Sequence Viewer
	AAN72312	(Get FASTA)	NCBI Sequence Viewer
	ABF47106	(Get FASTA)	NCBI Sequence Viewer
	BAG62553	(Get FASTA)	NCBI Sequence Viewer
	BAG62570	(Get FASTA)	NCBI Sequence Viewer
	CAA34672	(Get FASTA)	NCBI Sequence Viewer
	EAX06888	(Get FASTA)	NCBI Sequence Viewer
	EAX06889	(Get FASTA)	NCBI Sequence Viewer
	EAX06890	(Get FASTA)	NCBI Sequence Viewer
	EAX06891	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000271153
	ENSP00000271153.4
	ENSP00000360987
	ENSP00000360991
	ENSP00000360991.4
GenBank Protein	P13584	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001093242 ⟸ NM_001099772
- Peptide Label:	isoform a
- UniProtKB:	P13584 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLV LEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHD HTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQV YRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPLGPGSGK hide sequence

RefSeq Acc Id:	NP_000770 ⟸ NM_000779
- Peptide Label:	isoform b
- UniProtKB:	Q8WWU9 (UniProtKB/Swiss-Prot), Q8WWF2 (UniProtKB/Swiss-Prot), Q8TD85 (UniProtKB/Swiss-Prot), Q1HBI2 (UniProtKB/Swiss-Prot), Q8WWV0 (UniProtKB/Swiss-Prot), P13584 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLV LEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDH TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVY RQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPLGPGSGK hide sequence

RefSeq Acc Id:	NP_001306090 ⟸ NM_001319161
- Peptide Label:	isoform c
- UniProtKB:	Q8IZB0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGGRGLLVLEGPKWLQHRKLLTP GFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD EKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPLGPGSGK hide sequence

RefSeq Acc Id:	NP_001306091 ⟸ NM_001319162
- Peptide Label:	isoform d
- UniProtKB:	B4DV41 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILL GARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAV WPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPLGPGSGK hide sequence

RefSeq Acc Id:	NP_001306092 ⟸ NM_001319163
- Peptide Label:	isoform e
- UniProtKB:	B4DV41 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLG ARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVW PDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPLGPGSGK hide sequence

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P13584-F1-model_v2	AlphaFold	P13584	1-511	view protein structure

RGD ID:

6855446

Promoter ID:

EPDNEW_H888

Type:

multiple initiation site

Name:

CYP4B1_1

Description:

cytochrome P450 family 4 subfamily B member 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	46,799,046 - 46,799,106	EPDNEW

Database	Acc Id	Source(s)
COSMIC	CYP4B1	COSMIC
Ensembl Genes	ENSG00000142973	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000271153	ENTREZGENE
	ENST00000271153.8	UniProtKB/Swiss-Prot
	ENST00000371919	ENTREZGENE
	ENST00000371923	ENTREZGENE
	ENST00000371923.9	UniProtKB/Swiss-Prot
	ENST00000464439	ENTREZGENE
Gene3D-CATH	1.10.630.10	UniProtKB/Swiss-Prot
GTEx	ENSG00000142973	GTEx
HGNC ID	HGNC:2644	ENTREZGENE
Human Proteome Map	CYP4B1	Human Proteome Map
InterPro	Cyt_P450	UniProtKB/Swiss-Prot
	Cyt_P450_CS	UniProtKB/Swiss-Prot
	Cyt_P450_E_grp-I	UniProtKB/Swiss-Prot
	Cyt_P450_sf	UniProtKB/Swiss-Prot
	Cytochrome_P450_Monoox	UniProtKB/Swiss-Prot
KEGG Report	hsa:1580	UniProtKB/Swiss-Prot
NCBI Gene	1580	ENTREZGENE
OMIM	124075	OMIM
PANTHER	CYTOCHROME P450 4B1	UniProtKB/Swiss-Prot
	CYTOCHROME P450 FAMILY 4	UniProtKB/Swiss-Prot
Pfam	p450	UniProtKB/Swiss-Prot
PharmGKB	PA27119	PharmGKB
PRINTS	EP450I	UniProtKB/Swiss-Prot
	P450	UniProtKB/Swiss-Prot
PROSITE	CYTOCHROME_P450	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48264	UniProtKB/Swiss-Prot
UniProt	B4DV41	ENTREZGENE, UniProtKB/TrEMBL
	CP4B1_HUMAN	UniProtKB/Swiss-Prot
	E9PL36_HUMAN	UniProtKB/TrEMBL
	E9PML0_HUMAN	UniProtKB/TrEMBL
	F5H1Q8_HUMAN	UniProtKB/TrEMBL
	F5H5Q6_HUMAN	UniProtKB/TrEMBL
	P13584	ENTREZGENE
	Q1HBI2	ENTREZGENE
	Q8IZB0	ENTREZGENE, UniProtKB/TrEMBL
	Q8TD85	ENTREZGENE
	Q8WWF2	ENTREZGENE
	Q8WWU9	ENTREZGENE
	Q8WWV0	ENTREZGENE
	Q8WWV1_HUMAN	UniProtKB/TrEMBL
UniProt Secondary	Q1HBI2	UniProtKB/Swiss-Prot
	Q8TD85	UniProtKB/Swiss-Prot
	Q8WWF2	UniProtKB/Swiss-Prot
	Q8WWU9	UniProtKB/Swiss-Prot
	Q8WWV0	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-15	CYP4B1	cytochrome P450 family 4 subfamily B member 1	CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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