LOC102012414 (cytochrome P450 4B1) - Rat Genome Database

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Gene: LOC102012414 (cytochrome P450 4B1) Chinchilla lanigera
Analyze
Symbol: LOC102012414 (Ensembl: CYP4B1)
Name: cytochrome P450 4B1 (Ensembl:cytochrome P450 family 4 subfamily B member 1)
RGD ID: 9052817
Description: ENCODES a protein that exhibits heterocyclic compound binding (ortholog); medium-chain fatty acid omega-1 hydroxylase activity (ortholog); medium-chain fatty acid omega-hydroxylase activity (ortholog); INVOLVED IN biphenyl metabolic process (ortholog); fatty acid oxidation (ortholog); xenobiotic metabolic process (ortholog); PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; ASSOCIATED WITH autism spectrum disorder (ortholog); Breast Cancer, Familial (ortholog); cervical cancer (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546411,378,980 - 11,556,544 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495546411,539,467 - 11,556,519 (-)NCBIChiLan1.0ChiLan1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LOC102012414
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546411,378,980 - 11,556,544 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495546411,539,467 - 11,556,519 (-)NCBIChiLan1.0ChiLan1.0
CYP4B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38146,799,046 - 46,819,413 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl146,757,838 - 46,870,221 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37147,264,718 - 47,285,085 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36147,037,257 - 47,057,608 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34146,976,761 - 46,997,105NCBI
Celera145,552,027 - 45,572,396 (+)NCBICelera
Cytogenetic Map1p33NCBI
HuRef145,380,284 - 45,400,633 (+)NCBIHuRef
CHM1_1147,381,383 - 47,401,714 (+)NCBICHM1_1
T2T-CHM13v2.0146,676,425 - 46,696,812 (+)NCBIT2T-CHM13v2.0
Cyp4b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394115,481,895 - 115,504,918 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4115,476,281 - 115,504,999 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384115,624,698 - 115,647,721 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4115,624,725 - 115,647,723 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv374115,297,333 - 115,320,310 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364115,122,660 - 115,145,637 (-)NCBIMGSCv36mm8
Celera4114,360,727 - 114,383,719 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.06NCBI
Cyp4b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,375,807 - 134,413,635 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5134,375,807 - 134,393,116 (-)EnsemblGRCr8
mRatBN7.25129,139,019 - 129,176,860 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,139,038 - 129,156,348 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5131,749,529 - 131,766,903 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05133,504,409 - 133,521,783 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05133,526,563 - 133,543,937 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd5134,033,213 - 134,050,587 (-)NCBI
Lyon_Normotensive5136,010,786 - 136,028,162 (-)NCBI
Lyon_Hypertensive5135,197,962 - 135,215,338 (-)NCBI
F344_StmMcwi5128,761,078 - 128,778,386 (-)NCBI
Rnor_6.05134,508,728 - 134,526,103 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5134,508,730 - 134,526,089 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.05138,299,551 - 138,316,860 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45135,917,327 - 135,934,636 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5127,676,727 - 127,694,036 (-)NCBICelera
RGSC_v3.15135,922,552 - 135,939,862 (-)NCBI
RH 3.4 Map5823.3RGD
Cytogenetic Map5q35NCBI
CYP4B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21179,984,908 - 180,003,684 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,126,616 - 179,145,387 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0146,107,787 - 46,127,162 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1147,462,178 - 47,481,502 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl147,462,178 - 47,481,502 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
CYP4B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11513,676,631 - 13,694,483 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1513,676,371 - 13,694,705 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1513,796,940 - 13,814,798 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01513,826,980 - 13,844,834 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1513,826,737 - 13,844,877 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11513,628,060 - 13,645,902 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01513,696,377 - 13,714,240 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01513,765,891 - 13,783,754 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cyp4b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap11134,525,421 - 34,540,432 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_02440505861,881,092 - 61,957,546 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647427,767,371 - 27,782,008 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647427,705,874 - 27,782,328 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP4B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6164,718,444 - 164,737,552 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.16164,718,393 - 164,737,693 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26152,210,031 - 152,229,243 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CYP4B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap12090,059,798 - 90,079,002 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366603330,987,875 - 31,007,108 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.12085,997,796 - 86,018,649 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2085,996,269 - 86,018,055 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
LOC101725929
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249062,664,057 - 2,683,527 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046249062,663,940 - 2,684,171 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl75,642,876 - 5,662,365 (-)Ensembl
LOC116898076
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1139,349,162 - 39,366,808 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000010783   ⟹   ENSCLAP00000010651
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546411,378,980 - 11,556,544 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000010784   ⟹   ENSCLAP00000010652
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546411,379,071 - 11,415,620 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000010785   ⟹   ENSCLAP00000010653
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546411,539,467 - 11,556,544 (-)Ensembl
RefSeq Acc Id: XM_005398649   ⟹   XP_005398706
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546411,539,467 - 11,556,519 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005398650   ⟹   XP_005398707
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546411,539,467 - 11,554,718 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005398706 (Get FASTA)   NCBI Sequence Viewer  
  XP_005398707 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010651.1
  ENSCLAP00000010653
  ENSCLAP00000010653.1
RefSeq Acc Id: XP_005398706   ⟸   XM_005398649
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V5N9 (UniProtKB/TrEMBL),   A0A8C2V802 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005398707   ⟸   XM_005398650
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V802 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000010652   ⟸   ENSCLAT00000010784
Ensembl Acc Id: ENSCLAP00000010653   ⟸   ENSCLAT00000010785
Ensembl Acc Id: ENSCLAP00000010651   ⟸   ENSCLAT00000010783


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007349 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010783.1 UniProtKB/TrEMBL
  ENSCLAT00000010785 ENTREZGENE
  ENSCLAT00000010785.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/TrEMBL
  Cytochrome_P450_Monoox UniProtKB/TrEMBL
NCBI Gene LOC102012414 ENTREZGENE
PANTHER CYTOCHROME P450 4B1 UniProtKB/TrEMBL
  CYTOCHROME P450 FAMILY 4 UniProtKB/TrEMBL
Pfam p450 UniProtKB/TrEMBL
PRINTS EP450I UniProtKB/TrEMBL
  P450 UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/TrEMBL
UniProt A0A8C2V5N9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2V802 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 LOC102012414  cytochrome P450 4B1    cytochrome P450 4B1-like  Symbol and/or name change 5135510 APPROVED