Bp359 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bp359 (Blood pressure QTL 359) Rattus norvegicus

Symbol: Bp359
Name: Blood pressure QTL 359
RGD ID: 7365049
Previously known as: BP-f1
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.05133,351,969 - 140,120,264RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05137,146,119 - 143,913,027RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45134,909,988 - 141,744,732RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.SR-(rs65785750-rs106808193)/Opaz 



Candidate Gene Status
Cyp4a1 is a candidate Gene for Bp359
EDN2 is a candidate Gene for Bp359

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Dahl (S x R) congenic strain analysis confirms and defines a chromosome 5 female-specific blood pressure quantitative trait locus to <7 Mbp. Herrera VL, etal., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30.
2. Differential genetic basis for pre-menopausal and post-menopausal salt-sensitive hypertension. Herrera VL, etal., PLoS One. 2012;7(8):e43160. doi: 10.1371/journal.pone.0043160. Epub 2012 Aug 17.
Related QTLs

Related QTL Description Reference
Bp292 sub_region RGD:7364997


Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (rs105835643)
Rat AssemblyChrPosition (strand)Source
Rnor_6.05133,351,969 - 133,351,969RGD
Rnor_5.05137,146,119 - 137,146,119RGD
RGSC_v3.45134,909,988 - 134,909,988RGD
Flank 2: (rs106808193)
Rat AssemblyChrPosition (strand)Source
Rnor_6.05140,120,264 - 140,120,264RGD
Rnor_5.05143,913,027 - 143,913,027RGD
RGSC_v3.45141,744,732 - 141,744,732RGD
Celera5133,278,847 - 133,278,847RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general measurement method: 8% NaCl diet was started at 12 weeks of age and given for 12 weeks; non-stressed blood pressure measurements were taken by intra-aortic abdominal radiotelemetric implants over 10 seconds every 5 minutes for 24 hours 7364997
qtl_general animals used: 20 animals 7364997
qtl_general software used: one-way ANOVA 7364997
qtl_general region spans <7 Mbp (134.9–141.5 Mb) 7364997