Tas1r1 (taste 1 receptor member 1)

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Gene: Tas1r1 (taste 1 receptor member 1) Rattus norvegicus

Analyze

Symbol:

Tas1r1

Name:

taste 1 receptor member 1

RGD ID:

61891

Description:

Enables taste receptor activity. Involved in sensory perception of umami taste. Predicted to be located in membrane. Orthologous to human TAS1R1 (taste 1 receptor member 1); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

G protein-coupled receptor 70; G-protein coupled receptor 70; Gpr70; taste receptor type 1 member 1; taste receptor, type 1, member 1

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TAS1R1 (taste 1 receptor member 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tas1r1 (taste receptor, type 1, member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tas1r1 (taste 1 receptor member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TAS1R1 (taste 1 receptor member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TAS1R1 (taste 1 receptor member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tas1r1 (taste 1 receptor member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TAS1R1 (taste 1 receptor member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TAS1R1 (taste 1 receptor member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tas1r1 (taste 1 receptor member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tas1r1 (taste receptor, type 1, member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TAS1R1 (taste 1 receptor member 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tas1r1 (taste receptor, type 1, member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	162,533,838 - 162,546,408 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	162,533,841 - 162,545,562 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	165,237,016 - 165,248,575 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	5	167,057,883 - 167,069,920 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	5	167,020,083 - 167,032,120 (-)	NCBI	Rnor_WKY
Rnor_6.0	5	169,200,389 - 169,212,113 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	169,200,287 - 169,212,170 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	172,758,655 - 172,770,376 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	169,256,281 - 169,268,006 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	169,266,627 - 169,278,194 (-)	NCBI
Celera	5	160,766,538 - 160,778,257 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

aldehydo-D-glucose (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

aspartame (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

crocidolite asbestos (ISO)

D-glucose (ISO)

epoxiconazole (ISO)

gentamycin (EXP)

glucose (ISO)

Licochalcone B (ISO)

methamphetamine (EXP)

methotrexate (ISO)

monosodium L-glutamate (ISO)

paracetamol (EXP)

resveratrol (ISO)

SCH 23390 (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

trichloroethene (EXP)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of taste (IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of umami taste (IBA,IDA,ISO)

Cellular Component

membrane (IC)

plasma membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IBA)

taste receptor activity (IPI,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity.	Hoon MA, etal., Cell 1999 Feb 19;96(4):541-51.
3.	Human receptors for sweet and umami taste.	Li X, etal., Proc Natl Acad Sci U S A 2002 Apr 2;99(7):4692-6.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Tas1r1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	162,533,838 - 162,546,408 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	162,533,841 - 162,545,562 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	165,237,016 - 165,248,575 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	5	167,057,883 - 167,069,920 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	5	167,020,083 - 167,032,120 (-)	NCBI	Rnor_WKY
Rnor_6.0	5	169,200,389 - 169,212,113 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	169,200,287 - 169,212,170 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	172,758,655 - 172,770,376 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	169,256,281 - 169,268,006 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	169,266,627 - 169,278,194 (-)	NCBI
Celera	5	160,766,538 - 160,778,257 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

TAS1R1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	6,555,307 - 6,579,755 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	1	6,555,307 - 6,579,755 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	6,615,367 - 6,639,815 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	6,538,021 - 6,562,404 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	6,549,699 - 6,574,082	NCBI
Celera	1	5,729,206 - 5,753,685 (+)	NCBI		Celera
Cytogenetic Map	1	p36.31	NCBI
HuRef	1	5,763,083 - 5,787,754 (+)	NCBI		HuRef
CHM1_1	1	6,604,015 - 6,628,556 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	6,080,965 - 6,105,419 (+)	NCBI		T2T-CHM13v2.0

Tas1r1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	152,112,371 - 152,122,947 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	152,112,371 - 152,123,025 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	152,027,914 - 152,038,490 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	152,027,914 - 152,038,568 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	151,402,023 - 151,412,599 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	150,871,714 - 150,882,368 (-)	NCBI		MGSCv36	mm8
Celera	4	154,314,290 - 154,324,874 (-)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	82.83	NCBI

Tas1r1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	6,056,676 - 6,066,272 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955486	6,056,501 - 6,065,038 (-)	NCBI	ChiLan1.0	ChiLan1.0

TAS1R1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	6,572,142 - 6,594,138 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	6,572,142 - 6,594,138 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	5,317,757 - 5,341,053 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

TAS1R1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	60,397,116 - 60,405,855 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	60,397,116 - 60,405,696 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	60,406,335 - 60,415,395 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	60,612,462 - 60,621,532 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	60,612,783 - 60,621,373 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	60,611,537 - 60,620,607 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	60,478,212 - 60,487,284 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	60,880,332 - 60,889,402 (+)	NCBI		UU_Cfam_GSD_1.0

Tas1r1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	30,838,918 - 30,848,558 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936623	1,325,384 - 1,333,609 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936623	1,325,384 - 1,333,609 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TAS1R1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	67,396,856 - 67,410,638 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	67,396,471 - 67,410,236 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	62,350,073 - 62,363,598 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TAS1R1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	125,167,280 - 125,188,333 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	125,167,452 - 125,187,383 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	29,212,342 - 29,221,233 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tas1r1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	4,951,359 - 4,959,503 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624818	4,951,593 - 4,959,828 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tas1r1
48 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	69
Count of miRNA genes:	61
Interacting mature miRNAs:	67
Transcripts:	ENSRNOT00000013385
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	151113452	164465185	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	151113452	166875058	Rat
1549904	Neuinf1	Neuroinflammation QTL 1	3	0	nervous system integrity trait (VT:0010566)	blood T lymphocyte count (CMO:0000110)	5	154828214	166875058	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			1							19
Low	3	33	52	37	19	37	7	10	34	16	33	11	7
Below cutoff		10	4	4		4	1	1	38		8		1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053305	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF127389	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR460546	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000013385 ⟹ ENSRNOP00000013385

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	162,533,841 - 162,545,562 (-)	Ensembl
Rnor_6.0 Ensembl	5	169,200,287 - 169,212,170 (-)	Ensembl

RefSeq Acc Id:

NM_053305 ⟹ NP_445757

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,533,841 - 162,545,562 (-)	NCBI
Rnor_6.0	5	169,200,392 - 169,212,113 (-)	NCBI
Rnor_5.0	5	172,758,655 - 172,770,376 (-)	NCBI
RGSC_v3.4	5	169,256,281 - 169,268,006 (-)	RGD
Celera	5	160,766,538 - 160,778,257 (-)	RGD

Sequence:

show sequence

ATGCTCTTCTGGGCTGCTCACCTGCTGCTCAGCCTGCAGTTGGTCTACTGCTGGGCTTTCAGCT
GCCAAAGGACAGAGTCCTCTCCAGGCTTCAGCCTTCCTGGGGACTTCCTCCTTGCAGGTCTGTT
CTCCCTCCATGGTGACTGTCTGCAGGTGAGACACAGACCTCTGGTGACAAGTTGTGACAGGCCC
GACAGCTTCAACGGCCATGGCTACCACCTCTTCCAAGCCATGCGGTTCACTGTTGAGGAGATAA
ACAACTCCTCGGCCCTGCTTCCCAACATCACCCTGGGGTATGAGCTGTACGACGTGTGCTCAGA
ATCTGCCAATGTGTATGCCACCCTGAGGGTGCTTGCCCTGCAAGGGCCCCGCCACATAGAGATA
CAGAAAGACCTTCGCAACCACTCCTCCAAGGTGGTGGCCTTCATCGGGCCTGACAACACTGACC
ACGCTGTCACTACCGCTGCCTTGCTGGGTCCTTTCCTGATGCCCCTGGTCAGCTATGAGGCAAG
CAGCGTGGTACTCAGTGCCAAGCGCAAGTTCCCGTCTTTCCTTCGTACCGTCCCCAGTGACCGG
CACCAGGTGGAGGTCATGGTGCAGCTGCTGCAGAGTTTTGGGTGGGTGTGGATCTCGCTCATTG
GCAGCTACGGTGATTACGGGCAGCTGGGTGTGCAGGCGCTGGAGGAGCTGGCCGTGCCCCGGGG
CATCTGCGTCGCCTTCAAGGACATCGTGCCTTTCTCTGCCCGGGTGGGTGACCCGAGGATGCAG
AGCATGATGCAGCATCTGGCTCAGGCCAGGACCACCGTGGTTGTGGTCTTCTCTAACCGGCACC
TGGCTAGAGTGTTCTTCAGGTCCGTGGTGCTGGCCAACCTGACTGGCAAAGTGTGGGTCGCCTC
AGAAGACTGGGCCATCTCCACGTACATCACCAGCGTGACTGGGATCCAAGGCATTGGGACGGTG
CTCGGTGTGGCCGTCCAGCAGAGACAAGTCCCTGGGCTGAAGGAGTTTGAGGAGTCTTATGTCA
GGGCTGTAACAGCTGCTCCCAGCGCTTGCCCGGAGGGGTCCTGGTGCAGCACTAACCAGCTGTG
CCGGGAGTGCCACACGTTCACGACTCGTAACATGCCCACGCTTGGAGCCTTCTCCATGAGTGCC
GCCTACAGAGTGTATGAGGCTGTGTACGCTGTGGCCCACGGCCTCCACCAGCTCCTGGGATGTA
CTTCTGAGATCTGTTCCAGAGGCCCAGTCTACCCCTGGCAGCTTCTTCAGCAGATCTACAAGGT
GAATTTTCTTCTACATGAGAATACTGTGGCATTTGATGACAACGGGGACACTCTAGGTTACTAC
GACATCATCGCCTGGGACTGGAATGGACCTGAATGGACCTTTGAGATCATTGGCTCTGCCTCAC
TGTCTCCAGTTCATCTGGACATAAATAAGACAAAAATCCAGTGGCACGGGAAGAACAATCAGGT
GCCTGTGTCAGTGTGTACCACGGACTGTCTGGCAGGGCACCACAGGGTGGTTGTGGGTTCCCAC
CACTGCTGCTTTGAGTGTGTGCCCTGCGAAGCTGGGACCTTTCTCAACATGAGTGAGCTTCACA
TCTGCCAGCCTTGTGGAACAGAAGAATGGGCACCCAAGGAGAGCACTACTTGCTTCCCACGCAC
GGTGGAGTTCTTGGCTTGGCATGAACCCATCTCTTTGGTGCTAATAGCAGCTAACACGCTATTG
CTGCTGCTGCTGGTTGGGACTGCTGGCCTGTTTGCCTGGCATTTTCACACACCTGTAGTGAGGT
CAGCTGGGGGTAGGCTGTGCTTCCTCATGCTGGGTTCCCTGGTGGCCGGAAGTTGCAGCTTCTA
TAGCTTCTTCGGGGAGCCCACGGTGCCCGCGTGCTTGCTGCGTCAGCCCCTCTTTTCTCTCGGG
TTTGCCATCTTCCTCTCCTGCCTGACAATCCGCTCCTTCCAACTGGTCATCATCTTCAAGTTTT
CTACCAAGGTGCCCACATTCTACCGTACCTGGGCCCAAAACCATGGTGCAGGTCTATTCGTCAT
TGTCAGCTCCACGGTCCATTTGCTCATCTGTCTCACATGGCTTGTAATGTGGACCCCACGACCC
ACCAGGGAATACCAGCGCTTCCCCCATCTGGTGATTCTCGAGTGCACAGAGGTCAACTCTGTAG
GCTTCCTGTTGGCTTTCACCCACAACATTCTCCTCTCCATCAGTACCTTCGTCTGCAGCTACCT
GGGTAAGGAACTGCCAGAGAACTATAATGAAGCCAAATGTGTCACCTTCAGCCTGCTCCTCAAC
TTCGTATCCTGGATCGCCTTCTTCACCATGGCCAGCATTTACCAGGGCAGCTACCTGCCTGCGG
TCAATGTGCTGGCAGGGCTGACCACACTGAGCGGCGGCTTCAGCGGTTACTTCCTCCCCAAGTG
CTATGTGATTCTCTGCCGTCCAGAACTCAACAATACAGAACACTTTCAGGCCTCCATCCAGGAC
TACACGAGGCGCTGCGGCACTACCTGATCCACTGGAAAGGTGCAGACGGGAAGGAAGCCTCTCT
TCTTGTGCTGAAGGTGGCGGGTCCAGTGGGGCCGAGAGCTTGAGGTGTCTGGGAGAGCTCCGGC
ACAGCTTACGATGTATAAGCACGCGGAAGAATCCAGTGCAATAAAGACGGGAAGT

hide sequence

RefSeq Acc Id:

XM_008764341 ⟹ XP_008762563

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,533,838 - 162,545,512 (-)	NCBI
Rnor_6.0	5	169,200,389 - 169,211,959 (-)	NCBI

Sequence:

show sequence

TGAGACACAGACCTCTGGTGACAAGTTGTGACAGGGCTTTCCCTACAGGCCCGACAGCTTCAAC
GGCCATGGCTACCACCTCTTCCAAGCCATGCGGTTCACTGTTGAGGAGATAAACAACTCCTCGG
CCCTGCTTCCCAACATCACCCTGGGGTATGAGCTGTACGACGTGTGCTCAGAATCTGCCAATGT
GTATGCCACCCTGAGGGTGCTTGCCCTGCAAGGGCCCCGCCACATAGAGATACAGAAAGACCTT
CGCAACCACTCCTCCAAGGTGGTGGCCTTCATCGGGCCTGACAACACTGACCACGCTGTCACTA
CCGCTGCCTTGCTGGGTCCTTTCCTGATGCCCCTGGTCAGCTATGAGGCAAGCAGCGTGGTACT
CAGTGCCAAGCGCAAGTTCCCGTCTTTCCTTCGTACCGTCCCCAGTGACCGGCACCAGGTGGAG
GTCATGGTGCAGCTGCTGCAGAGTTTTGGGTGGGTGTGGATCTCGCTCATTGGCAGCTACGGTG
ATTACGGGCAGCTGGGTGTGCAGGCGCTGGAGGAGCTGGCCGTGCCCCGGGGCATCTGCGTCGC
CTTCAAGGACATCGTGCCTTTCTCTGCCCGGGTGGGTGACCCGAGGATGCAGAGCATGATGCAG
CATCTGGCTCAGGCCAGGACCACCGTGGTTGTGGTCTTCTCTAACCGGCACCTGGCTAGAGTGT
TCTTCAGGTCCGTGGTGCTGGCCAACCTGACTGGCAAAGTGTGGGTCGCCTCAGAAGACTGGGC
CATCTCCACGTACATCACCAGCGTGACTGGGATCCAAGGCATTGGGACGGTGCTCGGTGTGGCC
GTCCAGCAGAGACAAGTCCCTGGGCTGAAGGAGTTTGAGGAGTCTTATGTCAGGGCTGTAACAG
CTGCTCCCAGCGCTTGCCCGGAGGGGTCCTGGTGCAGCACTAACCAGCTGTGCCGGGAGTGCCA
CACGTTCACGACTCGTAACATGCCCACGCTTGGAGCCTTCTCCATGAGTGCCGCCTACAGAGTG
TATGAGGCTGTGTACGCTGTGGCCCACGGCCTCCACCAGCTCCTGGGATGTACTTCTGAGATCT
GTTCCAGAGGCCCAGTCTACCCCTGGCAGCTTCTTCAGCAGATCTACAAGGTGAATTTTCTTCT
ACATGAGAATACTGTGGCATTTGATGACAACGGGGACACTCTAGGTTACTACGACATCATCGCC
TGGGACTGGAATGGACCTGAATGGACCTTTGAGATCATTGGCTCTGCCTCACTGTCTCCAGTTC
ATCTGGACATAAATAAGACAAAAATCCAGTGGCACGGGAAGAACAATCAGGTGCCTGTGTCAGT
GTGTACCACGGACTGTCTGGCAGGGCACCACAGGGTGGTTGTGGGTTCCCACCACTGCTGCTTT
GAGTGTGTGCCCTGCGAAGCTGGGACCTTTCTCAACATGAGTGAGCTTCACATCTGCCAGCCTT
GTGGAACAGAAGAATGGGCACCCAAGGAGAGCACTACTTGCTTCCCACGCACGGTGGAGTTCTT
GGCTTGGCATGAACCCATCTCTTTGGTGCTAATAGCAGCTAACACGCTATTGCTGCTGCTGCTG
GTTGGGACTGCTGGCCTGTTTGCCTGGCATTTTCACACACCTGTAGTGAGGTCAGCTGGGGGTA
GGCTGTGCTTCCTCATGCTGGGTTCCCTGGTGGCCGGAAGTTGCAGCTTCTATAGCTTCTTCGG
GGAGCCCACGGTGCCCGCGTGCTTGCTGCGTCAGCCCCTCTTTTCTCTCGGGTTTGCCATCTTC
CTCTCCTGCCTGACAATCCGCTCCTTCCAACTGGTCATCATCTTCAAGTTTTCTACCAAGGTGC
CCACATTCTACCGTACCTGGGCCCAAAACCATGGTGCAGGTCTATTCGTCATTGTCAGCTCCAC
GGTCCATTTGCTCATCTGTCTCACATGGCTTGTAATGTGGACCCCACGACCCACCAGGGAATAC
CAGCGCTTCCCCCATCTGGTGATTCTCGAGTGCACAGAGGTCAACTCTGTAGGCTTCCTGTTGG
CTTTCACCCACAACATTCTCCTCTCCATCAGTACCTTCGTCTGCAGCTACCTGGGTAAGGAACT
GCCAGAGAACTATAATGAAGCCAAATGTGTCACCTTCAGCCTGCTCCTCAACTTCGTATCCTGG
ATCGCCTTCTTCACCATGGCCAGCATTTACCAGGGCAGCTACCTGCCTGCGGTCAATGTGCTGG
CAGGGCTGACCACACTGAGCGGCGGCTTCAGCGGTTACTTCCTCCCCAAGTGCTATGTGATTCT
CTGCCGTCCAGAACTCAACAATACAGAACACTTTCAGGCCTCCATCCAGGACTACACGAGGCGC
TGCGGCACTACCTGATCCACTGGAAAGGTGCAGACGGGAAGGAAGCCTCTCTTCTTGTGCTGAA
GGTGGCGGGTCCAGTGGGGCCGAGAGCTTGAGGTGTCTGGGAGAGCTCCGGCACAGCTTACGAT
GTATAAGCACGCGGAAGAATCCAGTGCAATAAAGACGGGAAGTGTG

hide sequence

RefSeq Acc Id:

XM_039109370 ⟹ XP_038965298

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	162,536,579 - 162,546,408 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_445757	(Get FASTA)	NCBI Sequence Viewer
	XP_008762563	(Get FASTA)	NCBI Sequence Viewer
	XP_038965298	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD18069	(Get FASTA)	NCBI Sequence Viewer
	EDL81214	(Get FASTA)	NCBI Sequence Viewer
	EDL81215	(Get FASTA)	NCBI Sequence Viewer
	Q9Z0R8	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_445757 ⟸ NM_053305
- Peptide Label:	precursor
- UniProtKB:	Q9Z0R8 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MLFWAAHLLLSLQLVYCWAFSCQRTESSPGFSLPGDFLLAGLFSLHGDCLQVRHRPLVTSCDRP DSFNGHGYHLFQAMRFTVEEINNSSALLPNITLGYELYDVCSESANVYATLRVLALQGPRHIEI QKDLRNHSSKVVAFIGPDNTDHAVTTAALLGPFLMPLVSYEASSVVLSAKRKFPSFLRTVPSDR HQVEVMVQLLQSFGWVWISLIGSYGDYGQLGVQALEELAVPRGICVAFKDIVPFSARVGDPRMQ SMMQHLAQARTTVVVVFSNRHLARVFFRSVVLANLTGKVWVASEDWAISTYITSVTGIQGIGTV LGVAVQQRQVPGLKEFEESYVRAVTAAPSACPEGSWCSTNQLCRECHTFTTRNMPTLGAFSMSA AYRVYEAVYAVAHGLHQLLGCTSEICSRGPVYPWQLLQQIYKVNFLLHENTVAFDDNGDTLGYY DIIAWDWNGPEWTFEIIGSASLSPVHLDINKTKIQWHGKNNQVPVSVCTTDCLAGHHRVVVGSH HCCFECVPCEAGTFLNMSELHICQPCGTEEWAPKESTTCFPRTVEFLAWHEPISLVLIAANTLL LLLLVGTAGLFAWHFHTPVVRSAGGRLCFLMLGSLVAGSCSFYSFFGEPTVPACLLRQPLFSLG FAIFLSCLTIRSFQLVIIFKFSTKVPTFYRTWAQNHGAGLFVIVSSTVHLLICLTWLVMWTPRP TREYQRFPHLVILECTEVNSVGFLLAFTHNILLSISTFVCSYLGKELPENYNEAKCVTFSLLLN FVSWIAFFTMASIYQGSYLPAVNVLAGLTTLSGGFSGYFLPKCYVILCRPELNNTEHFQASIQD YTRRCGTT hide sequence

RefSeq Acc Id:

XP_008762563 ⟸ XM_008764341

- Peptide Label:

isoform X1

- Sequence:

show sequence

MRFTVEEINNSSALLPNITLGYELYDVCSESANVYATLRVLALQGPRHIEIQKDLRNHSSKVVA
FIGPDNTDHAVTTAALLGPFLMPLVSYEASSVVLSAKRKFPSFLRTVPSDRHQVEVMVQLLQSF
GWVWISLIGSYGDYGQLGVQALEELAVPRGICVAFKDIVPFSARVGDPRMQSMMQHLAQARTTV
VVVFSNRHLARVFFRSVVLANLTGKVWVASEDWAISTYITSVTGIQGIGTVLGVAVQQRQVPGL
KEFEESYVRAVTAAPSACPEGSWCSTNQLCRECHTFTTRNMPTLGAFSMSAAYRVYEAVYAVAH
GLHQLLGCTSEICSRGPVYPWQLLQQIYKVNFLLHENTVAFDDNGDTLGYYDIIAWDWNGPEWT
FEIIGSASLSPVHLDINKTKIQWHGKNNQVPVSVCTTDCLAGHHRVVVGSHHCCFECVPCEAGT
FLNMSELHICQPCGTEEWAPKESTTCFPRTVEFLAWHEPISLVLIAANTLLLLLLVGTAGLFAW
HFHTPVVRSAGGRLCFLMLGSLVAGSCSFYSFFGEPTVPACLLRQPLFSLGFAIFLSCLTIRSF
QLVIIFKFSTKVPTFYRTWAQNHGAGLFVIVSSTVHLLICLTWLVMWTPRPTREYQRFPHLVIL
ECTEVNSVGFLLAFTHNILLSISTFVCSYLGKELPENYNEAKCVTFSLLLNFVSWIAFFTMASI
YQGSYLPAVNVLAGLTTLSGGFSGYFLPKCYVILCRPELNNTEHFQASIQDYTRRCGTT

hide sequence

RefSeq Acc Id:

ENSRNOP00000013385 ⟸ ENSRNOT00000013385

RefSeq Acc Id:	XP_038965298 ⟸ XM_039109370
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9Z0R8-F1-model_v2	AlphaFold	Q9Z0R8	1-840	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694297

Promoter ID:

EPDNEW_R4820

Type:

single initiation site

Name:

Tas1r1_1

Description:

taste 1 receptor member 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	169,212,196 - 169,212,256	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61891	AgrOrtholog
BioCyc Gene	G2FUF-39026	BioCyc
Ensembl Genes	ENSRNOG00000009708	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000013385	ENTREZGENE
	ENSRNOP00000013385.3	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000013385	ENTREZGENE
	ENSRNOT00000013385.6	UniProtKB/Swiss-Prot
Gene3D-CATH	2.10.50.30	UniProtKB/Swiss-Prot
	3.40.50.2300	UniProtKB/Swiss-Prot
InterPro	ANF_lig-bd_rcpt	UniProtKB/Swiss-Prot
	GPCR_3	UniProtKB/Swiss-Prot
	GPCR_3_9-Cys_dom	UniProtKB/Swiss-Prot
	GPCR_3_9-Cys_sf	UniProtKB/Swiss-Prot
	GPCR_3_C	UniProtKB/Swiss-Prot
	GPCR_3_Ca_sens_rcpt-rel	UniProtKB/Swiss-Prot
	GPCR_3_CS	UniProtKB/Swiss-Prot
	Peripla_BP_I	UniProtKB/Swiss-Prot
KEGG Report	rno:29407	UniProtKB/Swiss-Prot
NCBI Gene	29407	ENTREZGENE
PANTHER	PTHR24061	UniProtKB/Swiss-Prot
	TASTE RECEPTOR TYPE 1 MEMBER 1	UniProtKB/Swiss-Prot
Pfam	7tm_3	UniProtKB/Swiss-Prot
	ANF_receptor	UniProtKB/Swiss-Prot
	NCD3G	UniProtKB/Swiss-Prot
PhenoGen	Tas1r1	PhenoGen
PRINTS	GPCRMGR	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F3_2	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F3_3	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F3_4	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF53822	UniProtKB/Swiss-Prot
UniProt	Q9Z0R8	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-23	Tas1r1	taste 1 receptor member 1	Tas1r1	taste receptor, type 1, member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Tas1r1	taste receptor, type 1, member 1			Name updated	70584	APPROVED
2002-02-27	Tas1r1	taste receptor, type 1, member 1			Symbol and Name updated to reflect Human and Mouse nomenclature	70292	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar