Kpna6 (karyopherin subunit alpha 6)

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Gene: Kpna6 (karyopherin subunit alpha 6) Rattus norvegicus

Analyze

Symbol:

Kpna6

Name:

karyopherin subunit alpha 6

RGD ID:

1306570

Description:

Predicted to have nuclear import signal receptor activity. Predicted to be involved in several processes, including entry of viral genome into host nucleus through nuclear pore complex via importin; positive regulation of macromolecule metabolic process; and protein import into nucleus. Predicted to localize to cytoplasm and host cell. Orthologous to human KPNA6 (karyopherin subunit alpha 6); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

importin; importin subunit alpha-7; karyopherin (importin) alpha 6; karyopherin (importin) alpha 6-like; karyopherin alpha 6; karyopherin alpha 6 (importin alpha 7); LOC362607; MGC124892

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	141,988,111 - 142,021,483 (-)	NCBI
Rnor_6.0 Ensembl	5	147,850,275 - 147,886,615 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	5	147,852,738 - 147,867,600 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	5	151,581,761 - 151,594,918 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	148,783,562 - 148,793,599 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	148,793,600 - 148,803,633 (-)	NCBI
Celera	5	140,466,074 - 140,479,954 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP,ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

chloropicrin (ISO)

cisplatin (ISO)

clothianidin (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (EXP,ISO)

dibutyl phthalate (EXP)

elemental selenium (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

indole-3-methanol (EXP)

indometacin (ISO)

lead(0) (ISO)

lead(2+) (ISO)

pentachlorophenol (ISO)

pirinixic acid (ISO)

selenium atom (ISO)

Soman (EXP)

trimellitic anhydride (ISO)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

entry of viral genome into host nucleus through nuclear pore complex via importin (ISO)

maternal process involved in female pregnancy (ISO)

mitigation of host defenses by symbiont (ISO)

NLS-bearing protein import into nucleus (IBA)

positive regulation of cytokine production involved in inflammatory response (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

positive regulation of viral life cycle (ISO)

protein import into nucleus (ISO)

viral genome replication (ISO)

Cellular Component

cytoplasm (IEA)

host cell (IEA)

nucleoplasm (IBA)

nucleus (IBA)

Molecular Function

nuclear import signal receptor activity (IBA,ISO)

nuclear localization sequence binding (IBA)

protein binding (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	MGD data from the GO Consortium
4.	RGD automated data pipeline
5.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15689618	PMID:16906019	PMID:19946888	PMID:21479251	PMID:28189564

Genomics

Comparative Map Data

Kpna6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	141,988,111 - 142,021,483 (-)	NCBI
Rnor_6.0 Ensembl	5	147,850,275 - 147,886,615 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	5	147,852,738 - 147,867,600 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	5	151,581,761 - 151,594,918 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	148,783,562 - 148,793,599 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	148,793,600 - 148,803,633 (-)	NCBI
Celera	5	140,466,074 - 140,479,954 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

KPNA6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	32,108,056 - 32,176,563 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	32,108,043 - 32,176,563 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	32,573,657 - 32,642,164 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	32,346,231 - 32,414,756 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	1	32,242,749 - 32,307,867	NCBI
Celera	1	30,843,548 - 30,912,069 (+)	NCBI
Cytogenetic Map	1	p35.2	NCBI
HuRef	1	30,689,950 - 30,758,546 (+)	NCBI		HuRef
CHM1_1	1	32,689,241 - 32,757,720 (+)	NCBI		CHM1_1

Kpna6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	129,537,772 - 129,566,560 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	4	129,537,773 - 129,566,560 (-)	Ensembl
GRCm38	4	129,643,979 - 129,672,767 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	129,643,980 - 129,672,767 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	129,321,223 - 129,350,011 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	4	129,146,288 - 129,175,055 (-)	NCBI			mm8
Celera	4	127,976,916 - 128,007,095 (-)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI

Kpna6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	10,492,653 - 10,542,898 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	10,493,025 - 10,542,898 (+)	NCBI	ChiLan1.0	ChiLan1.0

KPNA6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	32,406,326 - 32,471,488 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	32,406,326 - 32,471,488 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	31,394,159 - 31,462,821 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

KPNA6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	2	69,030,228 - 69,077,912 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	2	69,025,409 - 69,078,635 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Kpna6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936474	15,168,344 - 15,229,864 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KPNA6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	88,611,462 - 88,656,278 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	88,611,128 - 88,656,281 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	82,613,725 - 82,640,028 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KPNA6
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	100,699,653 - 100,769,787 (-)	NCBI
ChlSab1.1 Ensembl	20	100,701,947 - 100,769,766 (-)	Ensembl

Kpna6
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624764	15,374,707 - 15,405,024 (+)	NCBI

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	114140832	159140832	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	142307322	173707219	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	136354114	173707219	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	116767924	161767924	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136640731	173707219	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	134712342	173707219	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	116767924	161767924	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	116767924	161767924	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138154677	172402610	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	134197905	173707219	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	116767924	161767924	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	134712342	173707219	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	112279412	157279412	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	112279412	157279412	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	112279412	157279412	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	112279412	157279412	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	131077716	173707219	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134502121	149030144	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	84963058	173504662	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	71552569	157225114	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	112279412	157279412	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40777918	154732375	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	102945579	154732228	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125455818	149568944	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133943857	173707219	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	47745646	167946134	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	107119214	152119214	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	61612600	168109659	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	61086525	149030144	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	142309061	173707219	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	134502140	157212422	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132551937	173707219	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	111278451	156278451	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133943857	173707219	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	125455818	157225114	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	100723739	153577831	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	128687766	173687766	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	97921932	149030144	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	114140832	159140832	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	254
Count of miRNA genes:	171
Interacting mature miRNAs:	190
Transcripts:	ENSRNOT00000000139
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	42	57	41	19	41	8	11	74	35	41	11	8
Low		1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001015029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY148303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY779030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC105813	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000000139 ⟹ ENSRNOP00000000139

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	147,853,243 - 147,867,583 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000087556 ⟹ ENSRNOP00000071158

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	147,850,275 - 147,886,615 (-)	Ensembl

RefSeq Acc Id:

NM_001015029 ⟹ NP_001015029

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	141,991,566 - 142,006,407 (-)	NCBI
Rnor_6.0	5	147,852,738 - 147,867,600 (-)	NCBI
Rnor_5.0	5	151,581,761 - 151,594,918 (-)	NCBI
RGSC_v3.4	5	148,783,562 - 148,793,599 (-)	RGD
Celera	5	140,466,074 - 140,479,954 (-)	NCBI

Sequence:

show sequence

CAGCCTCTGGGACAGCACAGGCTCAATCATGAAAAACTATGTGTCAGAGACCATGGCAAGCCCA
GGGAAAGACAATTATCGAATGAAGAGCTATAAGAACAATGCCTTAAACCCTGAGGAAATGAGAC
GAAGAAGGGAGGAAGAGGGCATTCAGCTTCGGAAACAGAAGCGGGAGCAGCAACTTTTTAAACG
GAGAAATGTGGAGCTGATTAATGAAGAAGCTGCCATGTTTGACAGTCTGCTGATGGATTCCTAC
GTGAGCTCCACAACTGGGGAGAGTGTGATCACAAGGGAAATGGTGGAGATGCTCTTTTCTGACG
ATTCTGACTTACAGTTAGCAACCACACAGAAATTCCGGAAACTCCTTTCCAAAGAGCCAAGTCC
TCCAATAGATGAAGTTATTAACACTCCAGGAGTAGTTGATCGGTTTGTGGAGTTTCTGAAGAGG
AGTGAGAATTGTACATTACAGTTTGAAGCTGCCTGGGCTCTAACAAACATTGCCTCTGGAACCT
CTCAGCAGACCAAAATTGTCATTGAAGCAGGAGCTGTCCCCATTTTTATAGAGCTGCTTAACTC
AGACTTTGAAGATGTACAAGAACAGGCAGTCTGGGCTCTTGGAAACATAGCTGGAGACAGTTCA
GTCTGCAGAGACTATGTCTTGAATTGTTCCATCCTTAATCCTCTGTTAACACTCCTTACTAAGT
CCACACGACTGACGATGACACGGAATGCAGTCTGGGCCCTGTCAAACCTCTGCCGAGGGAAGAA
CCCTCCTCCAGAGTTCGCAAAGGTCTCTCCTTGTTTGCCTGTATTGTCTCGCCTACTCTTCAGC
AGCGACTCAGACTTGCTGGCAGATGCTTGCTGGGCCCTCTCTTACCTGTCTGATGGCCCCAATG
AGAAGATCCAGGCAGTCATAGACTCTGGAGTCTGCCGGAGATTGGTAGAGCTTCTGATGCACAA
CGATTACAAAGTGGCGTCTCCTGCCTTGAGAGCTGTGGGTAATATTGTCACCGGGGATGATATC
CAGACCCAGGTCATTCTTAACTGTTCAGCCCTCCCTTGCCTCCTCCACCTGCTGAGCAGCTCTA
AGGAATCAATCCGGAAGGAAGCTTGCTGGACCATTTCAAACATCACTGCTGGCAACAGGGCTCA
AATACAGGCTGTCATAGATGCAAATATCTTCCCTGTATTGATCGAAATCCTTCAGAAAGCAGAG
TTCCGTACGAGGAAAGAAGCAGCCTGGGCCATCACCAATGCAACCTCAGGAGGAACCCCTGAGC
AAATCAGGTACTTGGTATCACTGGGCTGCATTAAGCCCCTGTGTGACTTGCTGACTGTAATGGA
TTCAAAAATTGTACAAGTGGCCCTCAATGGACTAGAGAACATTCTGCGGCTCGGAGAGCAAGAG
GGCAAGCGCAGTGGCTCAGGGGTCAATCCCTACTGTGGCCTCATCGAGGAAGCCTATGGCTTGG
ATAAGATTGAGTTTCTCCAGAGCCATGAGAACCAGGAGATCTACCAGAAGGCCTTTGACCTCAT
CGAGCACTACTTTGGTGTAGAGGATGACGACAGCAGCCTGGCCCCTCAGGTGGACGAGACTCAG
CAGCAGTTCATCTTCCAGCAGCCCGAGGCCCCCATGGAGGGCTTCCAGCTATAATGTCCGCCTC
CGGGGAGGGGGCAGGGCACGGCATGCACCAGCAGCCAGCAGAGGAGCAGCCTTCTGGTGGGCAG
GAGAACAGGCCCCACCAGCCCCGCACACCTGCTGCCCTGGACACTGTGTTCGTGACCTGCTCAC
CCCTTCCCTGGAGGAGGGAGTGCCCTCGGGACAGACAGAACCATCAGAGGCTCACAGTGGGTTT
GTGACAAGAAGGGGACGTGCGGGTCTATCTTCCTTACACTTTATTTTGGCTGCACACATGTCTT
TAACCCAGGAGCCCAGGGGTAGACAAAGGAGGACTGAGGTAATCAATTTGCACCTTTAAATTTT
TTTCTTTTATTTTCTTTAGTGGTGACTTCCTTCCCAGTTATCTTTCTTCATCCATCCCAGTCCT
CTGCCCTGACATGTGTAACTCTTGGGTACTTGAGCAGATGGAATATTCCAGAGGTGGGAGGTGG
GAGGGGAGGGGAGAAGTCCGAAACAAAGTGTTCTTGCTCTGACCGAAAAAAAAAAAAAAAAAAA
AAAAA

hide sequence

RefSeq Acc Id:

XM_039110358 ⟹ XP_038966286

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	141,988,111 - 142,021,483 (-)	NCBI

RefSeq Acc Id:

XM_039110360 ⟹ XP_038966288

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	141,988,111 - 142,020,821 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001015029	(Get FASTA)	NCBI Sequence Viewer
	XP_038966286	(Get FASTA)	NCBI Sequence Viewer
	XP_038966288	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI05814	(Get FASTA)	NCBI Sequence Viewer
	AAX07457	(Get FASTA)	NCBI Sequence Viewer
	EDL80567	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001015029 ⟸ NM_001015029

- UniProtKB:

Q3KR98 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKNYVSETMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEE
AAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTP
GVVDRFVEFLKRSENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQA
VWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVS
PCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPAL
RAVGNIVTGDDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTISNITAGNRAQIQAVIDANI
FPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALN
GLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDD
DSSLAPQVDETQQQFIFQQPEAPMEGFQL

hide sequence

RefSeq Acc Id:

ENSRNOP00000000139 ⟸ ENSRNOT00000000139

RefSeq Acc Id:

ENSRNOP00000071158 ⟸ ENSRNOT00000087556

RefSeq Acc Id:	XP_038966286 ⟸ XM_039110358
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038966288 ⟸ XM_039110360
- Peptide Label:	isoform X2

Protein Domains

IBB

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306570	AgrOrtholog
Ensembl Genes	ENSRNOG00000000127	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000000139	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000071158	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000000139	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000087556	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.690	UniProtKB/TrEMBL
	1.25.10.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7112648	IMAGE-MGC_LOAD
InterPro	ARM-like	UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/TrEMBL
	Arm_3	UniProtKB/TrEMBL
	Armadillo	UniProtKB/TrEMBL
	Importin-a-like_IBB-bd_dom	UniProtKB/TrEMBL
	Importin-a_IBB_sf	UniProtKB/TrEMBL
	Importing_su_alpha	UniProtKB/TrEMBL
KEGG Report	rno:362607	UniProtKB/TrEMBL
MGC_CLONE	MGC:124892	IMAGE-MGC_LOAD
NCBI Gene	362607	ENTREZGENE
Pfam	Arm	UniProtKB/TrEMBL
	Arm_3	UniProtKB/TrEMBL
	IBB	UniProtKB/TrEMBL
PhenoGen	Kpna6	PhenoGen
PIRSF	Importin_alpha	UniProtKB/TrEMBL
PROSITE	ARM_REPEAT	UniProtKB/TrEMBL
	IBB	UniProtKB/TrEMBL
SMART	ARM	UniProtKB/TrEMBL
Superfamily-SCOP	ARM-type_fold	UniProtKB/TrEMBL
UniProt	A0A0G2JZS1_RAT	UniProtKB/TrEMBL
	F1LT58_RAT	UniProtKB/TrEMBL
	Q3KR98	ENTREZGENE, UniProtKB/TrEMBL
	Q56R15_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-11	Kpna6	karyopherin subunit alpha 6	Kpna6	karyopherin alpha 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-01-27	Kpna6	karyopherin alpha 6	Kpna6	karyopherin alpha 6 (importin alpha 7)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-05-24	Kpna6	karyopherin alpha 6 (importin alpha 7)	LOC100363922	karyopherin (importin) alpha 6-like	Data Merged	1643240	APPROVED
2010-05-06	LOC100363922	karyopherin (importin) alpha 6-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-09-09	Kpna6	karyopherin alpha 6 (importin alpha 7)	Kpna6	karyopherin (importin) alpha 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Kpna6	karyopherin (importin) alpha 6	Kpna6_predicted	karyopherin (importin) alpha 6 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Kpna6_predicted	karyopherin (importin) alpha 6 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)