Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Yars1 (tyrosyl-tRNA synthetase 1) Rattus norvegicus
Analyze
Symbol: Yars1
Name: tyrosyl-tRNA synthetase 1
Description: Predicted to have tyrosine-tRNA ligase activity. Predicted to be involved in tyrosyl-tRNA aminoacylation. Predicted to localize to cytosol and nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate C. Orthologous to human YARS1 (tyrosyl-tRNA synthetase 1); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathway; tyrosinemia type III pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC313047; MGC112837; tyrosine--tRNA ligase, cytoplasmic; tyrosyl--tRNA ligase; tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase, cytoplasmic; tyrRS; Yars
Orthologs:
Homo sapiens (human) : YARS1 (tyrosyl-tRNA synthetase 1)  HGNC  Alliance
Mus musculus (house mouse) : Yars (tyrosyl-tRNA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Yars1 (tyrosyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : YARS1 (tyrosyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : YARS1 (tyrosyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Yars1 (tyrosyl-tRNA synthetase 1)
Sus scrofa (pig) : YARS1 (tyrosyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : YARS1 (tyrosyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Yars1 (tyrosyl-tRNA synthetase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05147,375,350 - 147,403,578 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5147,375,350 - 147,403,571 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05151,109,967 - 151,138,479 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45148,350,363 - 148,378,989 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15148,360,401 - 148,389,028 (+)NCBI
Celera5140,015,592 - 140,043,428 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Yars1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307616
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.