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Gene: Yars (tyrosyl-tRNA synthetase) Rattus norvegicus
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Symbol: Yars
Name: tyrosyl-tRNA synthetase
Description: Predicted to have tRNA binding activity and tyrosine-tRNA ligase activity. Predicted to be involved in tRNA aminoacylation for protein translation. Predicted to localize to the aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; and nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate C. Orthologous to human YARS (tyrosyl-tRNA synthetase); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathway; tyrosinemia type III pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC313047; MGC112837; tyrosine--tRNA ligase, cytoplasmic; tyrosyl--tRNA ligase; tyrosyl-tRNA synthetase, cytoplasmic; tyrRS
Orthologs:
Homo sapiens (human) : YARS (tyrosyl-tRNA synthetase)  HGNC  Alliance
Mus musculus (house mouse) : Yars (tyrosyl-tRNA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Yars (tyrosyl-tRNA synthetase)
Pan paniscus (bonobo/pygmy chimpanzee) : YARS (tyrosyl-tRNA synthetase)
Canis lupus familiaris (dog) : YARS (tyrosyl-tRNA synthetase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Yars (tyrosyl-tRNA synthetase)
Sus scrofa (pig) : YARS (tyrosyl-tRNA synthetase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05147,375,350 - 147,403,578 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05151,109,967 - 151,138,479 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45148,350,363 - 148,378,989 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15148,360,401 - 148,389,028 (+)NCBI
Celera5140,015,592 - 140,043,428 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Yars
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307616
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.