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Gene: Yars1 (tyrosyl-tRNA synthetase 1) Rattus norvegicus
Symbol: Yars1
Name: tyrosyl-tRNA synthetase 1
Description: Predicted to have tyrosine-tRNA ligase activity. Predicted to be involved in tyrosyl-tRNA aminoacylation. Predicted to localize to cytosol and nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate C. Orthologous to human YARS1 (tyrosyl-tRNA synthetase 1); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathway; tyrosinemia type III pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC313047; MGC112837; tyrosine--tRNA ligase, cytoplasmic; tyrosyl--tRNA ligase; tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase, cytoplasmic; tyrRS; Yars
Homo sapiens (human) : YARS1 (tyrosyl-tRNA synthetase 1)  HGNC  Alliance
Mus musculus (house mouse) : Yars (tyrosyl-tRNA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Yars1 (tyrosyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : YARS1 (tyrosyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : YARS1 (tyrosyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Yars1 (tyrosyl-tRNA synthetase 1)
Sus scrofa (pig) : YARS1 (tyrosyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : YARS1 (tyrosyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Yars1 (tyrosyl-tRNA synthetase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05147,375,350 - 147,403,578 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5147,375,350 - 147,403,571 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05151,109,967 - 151,138,479 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45148,350,363 - 148,378,989 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15148,360,401 - 148,389,028 (+)NCBI
Celera5140,015,592 - 140,043,428 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Yars1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307616
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.