Gene: Grik3 (glutamate ionotropic receptor kainate type subunit 3) Rattus norvegicus
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Symbol: Grik3
Name: glutamate ionotropic receptor kainate type subunit 3
Description: ENCODES a protein that exhibits glutamate receptor activity; ionotropic glutamate receptor activity; adenylate cyclase inhibiting G protein-coupled glutamate receptor activity (ortholog); INVOLVED IN negative regulation of synaptic transmission, glutamatergic; regulation of membrane potential; G protein-coupled glutamate receptor signaling pathway (ortholog); PARTICIPATES IN glutamate signaling pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); lung small cell carcinoma (ortholog); FOUND IN axon; dendrite; dendrite cytoplasm; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol
AGR Description: Exhibits ionotropic glutamate receptor activity; involved in negative regulation of glutamatergic synaptic transmission and regulation of membrane potential; localizes to the dendrite cytoplasm, perikaryon, and terminal bouton; orthologous to human GRIK3 (glutamate ionotropic receptor kainate type subunit 3).
Merged Description: Exhibits ionotropic glutamate receptor activity; involved in negative regulation of glutamatergic synaptic transmission and regulation of membrane potential; localizes to the dendrite cytoplasm, perikaryon, and terminal bouton; orthologous to human GRIK3 (glutamate ionotropic receptor kainate type subunit 3); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GluK3; gluR-7; GluR7; glutamate receptor 7; glutamate receptor ionotropic, kainate 3; glutamate receptor subunit kainate subtype; glutamate receptor, ionotropic kainate 3; glutamate receptor, ionotropic, kainate 3; kainate receptor
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05143,500,441 - 143,715,546 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05147,265,647 - 147,485,816 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45144,842,374 - 145,058,047 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15144,852,366 - 145,068,040 (+)NCBI
Celera5136,284,413 - 136,500,298 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Grik3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71027
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.