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Gene: Grik3 (glutamate ionotropic receptor kainate type subunit 3) Ictidomys tridecemlineatus

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Symbol:

Grik3

Name:

glutamate ionotropic receptor kainate type subunit 3

RGD ID:

12493979

Description:

ENCODES a protein that exhibits glutamate receptor activity (ortholog); identical protein binding (ortholog); INVOLVED IN negative regulation of synaptic transmission, glutamatergic (ortholog); regulation of membrane potential (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); lung small cell carcinoma (ortholog); FOUND IN axon (ortholog); cochlear hair cell ribbon synapse (ortholog); dendrite (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

glutamate receptor ionotropic, kainate 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	53,325,517 - 53,538,754 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	19,156,172 - 19,363,542 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	19,151,896 - 19,363,497 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease dominant intermediate C (ISO)

lung small cell carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway (IEA)

calcium-mediated signaling (IEA)

G protein-coupled glutamate receptor signaling pathway (IEA)

glutamate receptor signaling pathway (IEA)

ionotropic glutamate receptor signaling pathway (IEA)

monoatomic ion transmembrane transport (IEA)

monoatomic ion transport (IEA)

negative regulation of synaptic transmission, glutamatergic (ISO)

regulation of membrane potential (IEA,ISO)

regulation of presynaptic membrane potential (IEA)

Cellular Component

axon (ISO)

cochlear hair cell ribbon synapse (ISO)

dendrite (ISO)

dendrite cytoplasm (ISO)

glutamatergic synapse (IEA,ISO)

membrane (IEA)

perikaryon (ISO)

plasma membrane (IEA)

postsynaptic density membrane (IEA,ISO)

postsynaptic membrane (IEA)

presynaptic membrane (ISO)

synapse (IEA)

terminal bouton (ISO)

Molecular Function

adenylate cyclase inhibiting G protein-coupled glutamate receptor activity (IEA)

glutamate receptor activity (ISO)

glutamate-gated calcium ion channel activity (IEA)

glutamate-gated receptor activity (IEA)

identical protein binding (ISO)

kainate selective glutamate receptor activity (IEA)

ligand-gated monoatomic ion channel activity (IEA)

ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (IEA)

protein binding (ISO)

signaling receptor activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Grik3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	53,325,517 - 53,538,754 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	19,156,172 - 19,363,542 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	19,151,896 - 19,363,497 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GRIK3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	36,795,527 - 37,034,515 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	36,795,527 - 37,034,515 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	37,261,128 - 37,500,116 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	37,039,201 - 37,272,431 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	36,935,706 - 37,168,937	NCBI
Celera	1	35,537,937 - 35,776,956 (-)	NCBI		Celera
Cytogenetic Map	1	p34.3	NCBI
HuRef	1	35,378,101 - 35,617,482 (-)	NCBI		HuRef
CHM1_1	1	37,377,032 - 37,615,785 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	36,659,019 - 36,898,269 (-)	NCBI		T2T-CHM13v2.0

Grik3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	125,384,025 - 125,607,966 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	125,384,493 - 125,607,966 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	125,490,259 - 125,714,173 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	125,490,700 - 125,714,173 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	125,168,075 - 125,391,417 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	124,993,135 - 125,210,652 (+)	NCBI		MGSCv36	mm8
Celera	4	123,816,415 - 124,039,344 (+)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	58.91	NCBI

Grik3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	143,052,442 - 143,268,873 (+)	NCBI		GRCr8
mRatBN7.2	5	137,767,865 - 137,989,617 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	137,767,865 - 137,984,307 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	140,472,191 - 140,689,693 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	142,242,199 - 142,459,708 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	142,249,392 - 142,466,887 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	143,500,441 - 143,715,546 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	143,500,441 - 143,715,546 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	147,265,647 - 147,485,816 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	144,842,374 - 145,058,047 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	144,852,366 - 145,068,040 (+)	NCBI
Celera	5	136,284,413 - 136,500,298 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Grik3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	14,725,097 - 14,933,658 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	14,719,072 - 14,933,613 (-)	NCBI	ChiLan1.0	ChiLan1.0

GRIK3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	189,812,527 - 190,051,624 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	188,940,771 - 189,180,310 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	36,060,594 - 36,312,781 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	37,413,660 - 37,651,769 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	37,415,254 - 37,651,705 (-)	Ensembl	panpan1.1		panPan2

GRIK3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	5,331,746 - 5,550,975 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	5,331,717 - 5,549,181 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	5,577,336 - 5,796,363 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	5,469,481 - 5,690,516 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	5,468,814 - 5,690,461 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	5,323,496 - 5,544,551 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	5,389,938 - 5,612,163 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	5,405,832 - 5,626,868 (+)	NCBI		UU_Cfam_GSD_1.0

GRIK3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	92,880,303 - 93,128,569 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	92,880,297 - 93,128,048 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	85,950,875 - 86,193,744 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GRIK3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	95,832,480 - 96,069,890 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	95,832,864 - 96,063,577 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	20,731,558 - 20,968,669 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Grik3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	19,655,782 - 19,860,119 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	19,649,780 - 19,860,077 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005317826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040288387	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040288388	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000010644 ⟹ ENSSTOP00000009556

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936474	19,156,172 - 19,363,542 (-)	Ensembl

Ensembl Acc Id:

ENSSTOT00000034861 ⟹ ENSSTOP00000027905

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936474	19,156,172 - 19,235,997 (-)	Ensembl

RefSeq Acc Id:

XM_005317826 ⟹ XP_005317883

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	53,325,517 - 53,538,754 (-)	NCBI
SpeTri2.0	NW_004936474	19,151,896 - 19,363,497 (-)	NCBI

Sequence:

show sequence

TGGCGGCGCCCAACGATGACCGCTCCCTGGCGGCGCCTCCGGAGTCTGGTTTGGGAATACTGGG
CCGGGCTCCTCGTGTGCGCCTTCTGGATCCCAGACTCGCGCGGGATGCCCCACGTCATCCGGAT
CGGAGGAATCTTTGAGTATGCGGACGGCCCCAATGCCCAGGTCATGAACGCCGAGGAGCACGCC
TTCCGATTTTCCGCCAACATCATCAACAGGAACAGAACCCTGCTGCCCAACACCACCCTGACCT
ACGACATCCAGAGGATTCACTTCCACGACAGCTTTGAGGCCACTAAGAAGGCCTGCGATCAGCT
GGCCCTGGGCGTGGTGGCCATCTTCGGGCCGTCGCAGGGCTCCTGCACCAATGCCGTCCAGTCC
ATCTGCAACGCCCTGGAGGTGCCCCACATCCAGCTGCGCTGGAAGCACCACCCGCTGGACAACA
AGGACACCTTCTACGTGAACCTCTACCCCGACTACGCCTCTCTCAGCCACGCCATCCTCGATTT
GGTCCAGTACCTCAAGTGGCGGTCGGCCACCGTGGTCTATGACGACAGCACAGGGCTCATCCGG
CTGCAGGAGCTCATCATGGCTCCTTCAAGATACAACATCCGCCTCAAGATCCGCCAGCTCCCCA
TCGACTCGGACGACGCGCGCCCCCTGCTCAAGGAGATGAAGCGCGGCCGGGAGTTCCGCATCAT
CTTCGACTGCAGCCACACCATGGCCGCCCAGATCCTCAAGCAGGCCATGGCCATGGGCATGATG
ACCGAGTACTACCACTTCATCTTCACCACGCTGGATCTCTACGCACTAGACCTGGAGCCCTACC
GCTACTCCGGGGTGAACCTGACGGGGTTCCGCATCCTCAACGTGGACAACCCCCACGTCTCAGC
CATCGTGGAGAAGTGGTCCATGGAGCGGCTGCAGGCAGCTCCCCGAGCAGAGTCTGGCCTGTTG
GATGGAGTGATGATGACCGATGCGGCCTTACTGTACGATGCTGTCCACATCGTGTCCGTGTGCT
ACCAGCGGGCCCCCCAGATGACGGTGAACTCCCTGCAGTGCCATCGGCATAAGGCCTGGCGCTT
TGGTGGCCGCTTCATGAACTTCATCAAGGAGGCTCAATGGGAAGGATTAACTGGACGGATTGTT
TTCAACAAAACCAGTGGCTTGCGGACCGATTTTGATCTGGACATCATCAGCCTGAAGGAAGATG
GCCTGGAGAAGGTGGGGGTGTGGAGCCCCGCGGATGGGCTCAATATCACGGAGGTTGCCAAAGG
CCGAGGCCCTAATGTCACCGACTCTCTGACAAACAGGTCACTCATCGTCACCACCGTGCTGGAG
GAGCCCTTCGTCATGTTCCGGAAGTCCGACAGGACCCTGTACGGGAATGACCGCTTCGAGGGCT
ACTGCATTGACCTGCTCAAGGAGCTGGCCCACATCCTGGGCTTCTCCTATGAGATCCGGTTGGT
GGAGGACGGCAAGTACGGGGCGCAGGACGACAAGGGCCAGTGGAATGGCATGGTCAAGGAGCTC
ATCGACCACAAGGCGGACCTGGCCGTGGCTCCCCTGACCATCACGCATGTCCGTGAGAAGGCCA
TCGACTTCTCCAAGCCCTTCATGACGCTCGGAGTGAGCATCCTGTATCGCAAGCCCAACGGCAC
CAACCCCAGCGTGTTCTCCTTCCTCAACCCCCTGTCCCCGGACATCTGGATGTATGTGCTCCTC
GCCTACCTGGGTGTCAGCTGCGTCCTCTTCGTCATTGCCAGGTTCAGCCCCTATGAGTGGTACG
ATGCCCACCCCTGCAACCCGGGCTCCGAGGTGGTGGAGAACAACTTCACTCTGCTCAACAGCTT
CTGGTTTGGAATGGGCTCCCTCATGCAGCAAGGGTCTGAACTGATGCCCAAAGCTCTGTCCACG
CGCATCATCGGTGGCATCTGGTGGTTCTTCACGCTCATCATCATCTCCTCCTACACGGCCAACC
TGGCTGCCTTTCTGACCGTGGAGCGCATGGAATCGCCTATCGACTCCGCCGATGACCTGGCCAA
GCAAACCAAGATCGAGTACGGGGCTGTCAAGGACGGGGCCACCATGACCTTCTTCAAGAAATCC
AAGATCTCCACCTTCGAGAAGATGTGGGCTTTCATGAGCAGCAAGCCATCGGCGCTGGTGAAGA
ACAACGAGGAGGGCATCCAGCGGACGCTGACGGCGGACTACGCGCTGCTGATGGAGTCCACCAC
CATCGAATACGTCACCCAGAGGAACTGCAACCTCACCCAGATCGGGGGCCTCATCGACTCCAAG
GGCTACGGCATCGGCACACCCATGGGCTCCCCGTACAGGGACAAGATCACCATCGCCATCCTGC
AGCTGCAGGAGGAAGACAAGCTGCACATCATGAAGGAGAAGTGGTGGCGGGGCAGCGGGTGCCC
CGAGGAGGAGAACAAGGAGGCCAGCGCCCTGGGCATCCAGAAGATTGGCGGCATCTTCATCGTC
CTGGCCGCCGGGCTGGTCCTGTCTGTGCTGGTGGCCGTGGGCGAGTTCGTGTACAAGCTCCGCA
AGACAGCAGAGAGAGAACAGCGTTCCTTCTGCAGCACTGTGGCCGATGAGATCCGTTTCTCCCT
CACCTGCCAGCGTCGGGTCAAGCACAAGCCACAGCCTCCCATGATGGTCAAGACCGACGCCGTC
ATCAACATGCACACATTCAATGACCGCCGGCTTCCGGGCAAGGACAGCATGACCTGCAGCACAT
CCTTAGCCCCTGTGTTCCCCTAGGCTCATGTGGGGTGGGGACCACAGGCCTGACGCCAGGTAAA
AGAAACTGGAAACTGGAAAGGATATCCCCATCCCCCATGCTGAGCTTGGGGACCAGAGCTACTG
CCTGCATGTGGGGCCAGGAACTCTCAGCCCCGACCCACCAGGAAACCAGCAGGCCTCAGGCCCG
CTGTGGGGGCTTCCTTCTCCTCCTGTCTCTTCTGTGGGTTTCTAAAGCTGCCAGCCAAGATAGC
CAAGGCCAAAGGAAGCACATGCCTCTCTCAGGCCAAACTCACCGCCCCCGCCCCCAACTTTCCT
CTAGAGTCAGGCCACAGGAAACGGGAAATAGATCTTCTGTTGCCACTCCTTCCCCAAGAGCCCA
AGCCTTCTTGGTCTTGACCATGAGACCAGAGATGCAAAACTGGGCACCTTGAGGATCTTGGAGT
GGGGTTGCCAATGGAAACCCAAGGATGGTCATCCCCTGCAGCTGGGTAAAAGGAAGACTTCAGC
CCCTGAGGGCGGGTCACATGGCCCTGATCTTCTAGACTTGGCTTGACCCATGGCAGCCCTTTGG
CCAAGTTGAAGGCAGAATGAAAAAGAGGAGAGAAGAGAATGCACAGATAGAAGCCGCCATTTTG
AATCCTTACGGATAATGTCCCGATGGCTCCCACTCCTCTAAAAGGGGTAATAGTCACCTCGAAT
TCAGAGGAGAGAGGACCCCATGTGTCTCTCACAAAGGATGCCCAAAGATCCATCTGATATTTGA
AGCCCAGGAGAGGAACTGTGGATTCCATGAAAAAAATCCACAAGCCCTTGAGCCACGGACCTTG
CTTTGCCGGTCACCGAGCTGTTTTCTAAACCTCGTTGGCATTTGGGAACCTGGGATCTACCGTC
TACTCATCACCCACTCCTAGCCAGTTGAACTTGGCCTTGCTTTCATCTTGAAAGAATGACCTCG
ATTGAAGTGAAAGTCAAGTTTTCCCTTCTTAAAAGAGGGGTCAGTGTCCTATTGAACGGGCTAG
CTTTGGGGTAGGTGGGAAAATCCTGAGGGGACCCAAATAACTCCTGCCCTGGAACAGAAGGTTT
TGAGGAATGGGATAGACATAGGCCCCAAGGGCAGGGAGGGAGAAGCTGCCTCCTGGAGAATTAA
CCAAAGACCCAACACAGAGACACAGGCCCTCCTGGCCCCTGGTCTCTTCTCTGGAGCAGCTACG
GCCTTGCTGGGCTTGGGGGAGAGAGCAACCTGTGGGGTGCCGGGGAGGGAGGCAGACCAGATGG
TCTGGGGGTTCCACCTTGCTATCATGGATTCTCTAGAGTCTTGGAGAAGAATGAGACATGAAGG
GTCAGGTGCAAAGTGTCCTTAAAGAGTGCATTGTGGGGCCAGCAGGCCTCCCGTGGCCAAGGGT
AGAGGATAGTTTCTGGGCAAGGTAGAGAGGGCCGGAAGTTCTGGACCGAGGACCAGGGGACAAC
AGCCACTTCTCCCCCCCTGCCCTGGTGCTCCTGGGAATCCAGTGAGAGGAGCCACAATTCTGCC
TCCAGGGCCTTGTCAATGGGGGTGAAGCACCCTCCCCGGGCACGTGAGATGGAGGCTGTCTCTC
CTCCAGACTGAGCGGGACCCCCACCCCCATGGTTCCCGGAATCACAGCAGGACGGGCTACACTG
GAGGAGGGACCCGAGGGCTAGACTGCCGCGGAGCCCAGGGCACAGATGATAGGAAAAGCCATGC
TGTCGTGAGCTCTGCGGGGTCGCGGGAGTGTGCACGTGGATTTGTCTCTGTAAGTGTGAGCTTG
GGGGTTGAGGGGGGGAAACTGATCTGGACATATAATGTCCAGGGCACACAATAATAGGTGACCT
TTTGGGATCTGGCATGTGTGTGTGTGTGTGTGTGTGCGTGCGTGCGCGCATGTGTGTGTGCACA
TAAGTGAACTGAGGACTAGGAAGACATATCTGAACCAGCAGTAGAACCCCATTTATGTAAAAAC
AGGAGAAGCCATGTTGTAACGGGGTTCTGATGAGTACACAGAGGTACGCATATAGGCACGGTGT
GTCGGCTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACGCACACATTCATACACTGAATGGC
AGAGGATGGAGGGCAGGTGAGGCCTGCAGCACAGCCAAATACGTGTAAAAGGAGAAGCCATGTC
ATCAAGGGGGCCACGTGTGAGCAGTGTGCACACGGGTAGGCTTGTGTGCCCAGCAGAGAGCAGG
GGGTGGGCAGAACCAGAGTGTCACGCAGCATGGGTCCACACATAGGGCATGCGAGGAGCATGTG
GAACTGGAGTTTGTGACTGCGTGTGTGAGTGTGCTCGTGCCCAAGTGTTTCGGATGCACATGTG
TGTTCCAGCTCACGGCAGGAGCAGAGACGGACAATCAACCAGGAAGGCGGGACATCAGGGTCTG
TTTGCAGTCCTATCACCTAGGGATTGTGTGTCACAGATATGGGGAGATGGCATGGGTGTGTGCA
CAGGTGACGTCCCCGTGGGGAATCCCTGCAGGGGCTCATGGCTGGTGACTCCTCTGCTGTAGGC
AGAGTGCCCTGTTAGAAGGGAAAACAGCTTTGTCTTTGTGATTCCTGATACCGGGATTCTAATG
AGCGCAGGTACCAATTCCCTCCCACCTTCCCCAGTCATGGACCACTGTCTCACTTTGTCAGATA
TGACTTCATAGCACATGCCACGTCCACGCTCATGGCTCACACGTGTGCTTCCGTGTAGGACGCT
GTACGTGCGTGTCGTGTTCTTCTGAGGCTACGCACCTGTGGAGATTGTGATAGACAAAAGGGAG
GTGACGTGGGGTTGGAAGTTTTTCATAAAAGGAATGAAGAATGGTTGATAAACAGGCACAATTC
AACGAGGGCAGTCCCCAAAAGGTACTGAAATGGTTTCTAGACTCTTCCGTGGAGGTGGGATGGC
ACACTTCCTGGTCTGTCCCCTCCTCGCCTGTGTCCAGAGGTGTGGCTAGTGTTCAGCCTCTGGC
TGATGTTCCAGAGACCCGCCCAACGGGCCAGGTGCACTGAGACGGCACTGCCTGGGGCCAAGCT
GTCCCTCCCAGGGTGCTGAAGGTGGCGCTCCCTCTGTGAGGCGGGAGGGGAGGAGGGTGCTGAG
GGAGGTGCTCTGGGCGAGAAGGATCAAGGGTTCTTACGGTTGGGGCCTGTGCTGCCCCCCCGGG
GGGGGGGGGTGCAGCTGAGCCGGGGCAGAGCCACGCCTGTGTGTGTGTGTCGGGGCACACGTGG
AGGGACAGGAGGCATGAAAGCTGGTGCAGATGGAGCAGAAGGTGGACGGTGCCTGAGCAGGTGC
TTAAACATCCCCATCTGGTCCCACATGCCAGCGCTGAGCAGAGGAAGGCCCTCTCCACAATGCC
TGCGTCTGTCCACGCCCTCCTGCTGGCCAAACCGAGGAGAGGCCACCCCACCCGACAGTGAGCC
CTCCTCTGCCTCTCCCTCCACCTGCTGTGGGCAGACGAGAAACCCTGAGAGCTCTGTTGGCACT
GGGGCGGCCCCACTCTGCAAGTGTCTTACAAGAGGGAAAGTGCCCCACTGGCCAGTCGGCTGGA
CTCTGCATCCCTGAGGATGGAGGACCACCCCTCCTCAGTCCAGATGCAGCCTCCAGGCTGGAAG
AGCTCAGCTGGGCTCTGCCCCAACAGCCTCACACCAGAAGATGGAAACCCTGGCCCAGGATGTG
GGAGGGGTCCAAACCGCTTCCCTCCTGGAAAGCAGAAGTCAGACCCTGGCACAGATTCACCAAG
ATGAGTCAGAAGCCCCTCCCTGCCTGCTTTTCCAAGAGGGGGTCCCGGGAGCAGCTTCAGGCTT
CCTCACTCAGCATGAAGTTGGCGCCTCCCTGAGTCACGCCGCCGTTTTGCACGAACATCAGAAA
ACAGGTTCAACTCATTGGCCCACATCTGGAGTGGCCTGCATGGATACCCATCTGGAAAGGCCTC
ATGATGTGGACAGACAGTTGTAGGAGTTTAATAACATCTGGGGCCAGCCAGTCCCATGGACAGA
TGAGAAAAGAAAAAGAAAACACTCATGGGCCCAGCTCTGTGAAGGGGTCTGTGGATTAGACACA
TCTGGAAGTTCCAGGTTGGATGGACACATCTGGAATGAGCCCAGACTCTTGCCACCGTGGAAGG
GCCCTGCCCTCTGTCCCCAGGCTGGTTGGACTCAAGACCTCATTTCAGTCCTGATTTGCCCTGA
TGTTAAAATTTTCAGAGCTGAGGTGGTACACGAAATCACCAAACAGTTTTAGGTAGAAGGTTAA
TGTTCTGTACA

hide sequence

RefSeq Acc Id:

XM_040288387 ⟹ XP_040144321

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	53,331,447 - 53,538,754 (-)	NCBI

RefSeq Acc Id:

XM_040288388 ⟹ XP_040144322

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	53,325,517 - 53,432,962 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005317883	(Get FASTA)	NCBI Sequence Viewer
	XP_040144321	(Get FASTA)	NCBI Sequence Viewer
	XP_040144322	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000009556.3
	ENSSTOP00000027905.1
GenBank Protein	KAG3282764	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005317883 ⟸ XM_005317826
- Peptide Label:	isoform X1
- UniProtKB:	I3MFW3 (UniProtKB/TrEMBL), A0A287D310 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTAPWRRLRSLVWEYWAGLLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAFRFSA NIINRNRTLLPNTTLTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNAL EVPHIQLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELI MAPSRYNIRLKIRQLPIDSDDARPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTEYYH FIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRAESGLLDGVMM TDAALLYDAVHIVSVCYQRAPQMTVNSLQCHRHKAWRFGGRFMNFIKEAQWEGLTGRIVFNKTS GLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTVLEEPFVM FRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKA DLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGV SCVLFVIARFSPYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGG IWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTF EKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYVTQRNCNLTQIGGLIDSKGYGIG TPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCPEEENKEASALGIQKIGGIFIVLAAGL VLSVLVAVGEFVYKLRKTAEREQRSFCSTVADEIRFSLTCQRRVKHKPQPPMMVKTDAVINMHT FNDRRLPGKDSMTCSTSLAPVFP hide sequence

RefSeq Acc Id:	XP_040144322 ⟸ XM_040288388
- Peptide Label:	isoform X3
- UniProtKB:	A0A287D310 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040144321 ⟸ XM_040288387
- Peptide Label:	isoform X2
- UniProtKB:	A0A287D310 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSSTOP00000009556 ⟸ ENSSTOT00000010644

Ensembl Acc Id:

ENSSTOP00000027905 ⟸ ENSSTOT00000034861

Protein Domains

Ionotropic glutamate receptor C-terminal Ionotropic glutamate receptor L-glutamate and

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000010632	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000010644.3	UniProtKB/TrEMBL
	ENSSTOT00000034861.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.70	UniProtKB/TrEMBL
	3.40.50.2300	UniProtKB/TrEMBL
	Periplasmic binding protein-like II	UniProtKB/TrEMBL
InterPro	ANF_lig-bd_rcpt	UniProtKB/TrEMBL
	Glu/Gly-bd	UniProtKB/TrEMBL
	Iono_rcpt_met	UniProtKB/TrEMBL
	Ionotropic_Glu_rcpt	UniProtKB/TrEMBL
	Iontro_rcpt	UniProtKB/TrEMBL
	Peripla_BP_I	UniProtKB/TrEMBL
NCBI Gene	Grik3	ENTREZGENE
PANTHER	IONOTROPIC GLUTAMATE RECEPTOR	UniProtKB/TrEMBL
Pfam	ANF_receptor	UniProtKB/TrEMBL
	Lig_chan	UniProtKB/TrEMBL
	Lig_chan-Glu_bd	UniProtKB/TrEMBL
PRINTS	NMDARECEPTOR	UniProtKB/TrEMBL
SMART	Lig_chan-Glu_bd	UniProtKB/TrEMBL
	PBPe	UniProtKB/TrEMBL
Superfamily-SCOP	Periplasmic binding protein-like II	UniProtKB/TrEMBL
	SSF53822	UniProtKB/TrEMBL
UniProt	A0A287D310	ENTREZGENE, UniProtKB/TrEMBL
	I3MFW3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD