Trim62 (tripartite motif-containing 62)

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Gene: Trim62 (tripartite motif-containing 62) Rattus norvegicus

Analyze

Symbol:

Trim62

Name:

tripartite motif-containing 62

RGD ID:

1586169

Description:

Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of viral transcription; positive regulation of NF-kappaB transcription factor activity; and positive regulation of antifungal innate immune response. Predicted to act upstream of or within negative regulation of epithelial to mesenchymal transition. Predicted to be active in cytoplasm. Orthologous to human TRIM62 (tripartite motif containing 62); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; gentamycin.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

E3 ubiquitin-protein ligase TRIM62; LOC313045; similar to tripartite motif-containing 62; tripartite motif-containing protein 62

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	141,230,830 - 141,260,629 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	141,231,523 - 141,259,915 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	5	147,068,725 - 147,099,024 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	147,069,616 - 147,095,242 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	150,799,760 - 150,830,499 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	5	139,714,974 - 139,746,021 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease dominant intermediate C (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dinitrobenzenesulfonic acid (ISO)

2-hydroxypropanoic acid (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

CGP 52608 (ISO)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

fulvestrant (ISO)

gentamycin (EXP)

hydroquinone (ISO)

leflunomide (ISO)

methapyrilene (ISO)

miconazole (ISO)

nickel sulfate (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

phenylmercury acetate (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sunitinib (ISO)

trichostatin A (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

innate immune response (IBA,ISO)

negative regulation of epithelial to mesenchymal transition (ISO)

negative regulation of viral transcription (ISO)

positive regulation of antifungal innate immune response (ISO)

positive regulation of DNA-binding transcription factor activity (ISO)

positive regulation of DNA-templated transcription (IEA)

positive regulation of I-kappaB kinase/NF-kappaB signaling (IBA,ISO)

positive regulation of NF-kappaB transcription factor activity (IBA,ISO)

protein K27-linked ubiquitination (ISO)

protein ubiquitination (IBA)

regulation of viral entry into host cell (ISO)

viral release from host cell (ISO)

Cellular Component

cytoplasm (IBA,ISO)

Molecular Function

identical protein binding (ISO)

protein binding (ISO)

transcription coactivator activity (ISO)

ubiquitin protein ligase activity (IBA)

ubiquitin-protein transferase activity (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:18248090	PMID:23077300	PMID:23402750	PMID:24890125

Genomics

Comparative Map Data

Trim62
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	141,230,830 - 141,260,629 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	141,231,523 - 141,259,915 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	5	147,068,725 - 147,099,024 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	147,069,616 - 147,095,242 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	150,799,760 - 150,830,499 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	5	139,714,974 - 139,746,021 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

TRIM62
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	33,145,399 - 33,182,043 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	1	33,145,399 - 33,182,059 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	33,611,000 - 33,647,644 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	33,383,591 - 33,419,854 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	33,280,096 - 33,316,360	NCBI
Celera	1	31,881,193 - 31,917,797 (-)	NCBI		Celera
Cytogenetic Map	1	p35.1	NCBI
HuRef	1	31,726,962 - 31,763,317 (-)	NCBI		HuRef
CHM1_1	1	33,726,505 - 33,763,168 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	33,005,274 - 33,041,915 (-)	NCBI		T2T-CHM13v2.0

Trim62
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	128,777,837 - 128,805,119 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	128,777,373 - 128,805,121 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	128,884,044 - 128,911,326 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	128,883,580 - 128,911,328 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	128,561,384 - 128,588,570 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	128,386,444 - 128,413,630 (+)	NCBI		MGSCv36	mm8
Celera	4	127,221,836 - 127,249,023 (+)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI

Trim62
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	11,347,741 - 11,378,040 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	11,348,001 - 11,377,413 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRIM62
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	33,614,555 - 33,650,859 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	33,614,555 - 33,650,859 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	32,429,824 - 32,467,185 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

TRIM62
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	68,247,138 - 68,265,530 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	68,247,139 - 68,264,754 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	64,814,365 - 64,845,785 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	68,798,384 - 68,829,793 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	68,798,365 - 68,829,788 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	65,611,056 - 65,642,474 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	66,633,570 - 66,665,005 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	67,625,508 - 67,656,947 (+)	NCBI		UU_Cfam_GSD_1.0

Trim62
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	50,174,190 - 50,204,740 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936474	15,998,996 - 16,029,555 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIM62
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	89,406,478 - 89,442,746 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	89,406,470 - 89,442,794 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	83,434,103 - 83,470,360 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRIM62
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	99,697,568 - 99,731,660 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	99,698,497 - 99,731,379 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	16,958,127 - 16,993,441 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trim62
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	16,200,539 - 16,230,780 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	16,200,539 - 16,230,713 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Trim62
155 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	69
Count of miRNA genes:	61
Interacting mature miRNAs:	67
Transcripts:	ENSRNOT00000072908
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	94858972	143070159	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	129132428	143070159	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	120740824	143608494	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat

Markers in Region

D5Rat238

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	141,235,860 - 141,236,088 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	147,072,901 - 147,073,128	NCBI	Rnor6.0
Rnor_5.0	5	150,803,306 - 150,803,533	UniSTS	Rnor5.0
Celera	5	139,718,888 - 139,719,115	UniSTS
SHRSP x BN Map	5	78.5399	RGD
SHRSP x BN Map	5	78.5399	UniSTS
Cytogenetic Map	5	q13	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			2						39		18
Low	3	39	25	13	17	13	3	6	35	35	23	11	3
Below cutoff		4	30	28	2	28	5	5					5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_001060201	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111527	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_232757	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000072908 ⟹ ENSRNOP00000066009

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	147,069,616 - 147,095,242 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000110102 ⟹ ENSRNOP00000096911

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	141,231,523 - 141,259,915 (+)	Ensembl

RefSeq Acc Id:

XM_039111527 ⟹ XP_038967455

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	141,230,830 - 141,260,629 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_038967455	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL80515	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

ENSRNOP00000066009 ⟸ ENSRNOT00000072908

RefSeq Acc Id:	XP_038967455 ⟸ XM_039111527
- UniProtKB:	M0R947 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000096911 ⟸ ENSRNOT00000110102

Protein Domains

B box-type B30.2/SPRY RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0R947-F1-model_v2	AlphaFold	M0R947	1-475	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1586169	AgrOrtholog
BioCyc Gene	G2FUF-39831	BioCyc
Ensembl Genes	ENSRNOG00000049496	Ensembl
	ENSRNOG00000067048	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000096911	ENTREZGENE
	ENSRNOP00000096911.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000110102	ENTREZGENE
	ENSRNOT00000110102.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.920	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
InterPro	B30.2/SPRY	UniProtKB/TrEMBL
	B30.2/SPRY_sf	UniProtKB/TrEMBL
	Butyrophylin	UniProtKB/TrEMBL
	ConA-like_dom	UniProtKB/TrEMBL
	PRY	UniProtKB/TrEMBL
	PRY/SPRY_TRIM62	UniProtKB/TrEMBL
	SPRY_rcpt	UniProtKB/TrEMBL
	Znf_B-box	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
NCBI Gene	313045	ENTREZGENE
Pfam	PRY	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
	zf-B_box	UniProtKB/TrEMBL
PhenoGen	Trim62	PhenoGen
PRINTS	BUTYPHLNCDUF	UniProtKB/TrEMBL
PROSITE	B302_SPRY	UniProtKB/TrEMBL
	ZF_BBOX	UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
SMART	PRY	UniProtKB/TrEMBL
	RING	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
Superfamily-SCOP	ConA_like_lec_gl	UniProtKB/TrEMBL
UniProt	M0R947	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Trim62	tripartite motif-containing 62	Trim62	tripartite motif-containing 62	Data Merged	737654	PROVISIONAL
2021-08-09	Trim62	tripartite motif-containing 62			Symbol and Name status set to provisional	45752	PROVISIONAL
2008-03-05	Trim62	tripartite motif-containing 62	LOC313045	similar to tripartite motif-containing 62	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	LOC313045	similar to tripartite motif-containing 62			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar