Taf12 (TATA-box binding protein associated factor 12) - Rat Genome Database

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Gene: Taf12 (TATA-box binding protein associated factor 12) Rattus norvegicus
Analyze
Symbol: Taf12
Name: TATA-box binding protein associated factor 12
RGD ID: 1592841
Description: Predicted to enable several functions, including DNA-binding transcription factor binding activity; TBP-class protein binding activity; and transcription coactivator activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly; mRNA transcription by RNA polymerase II; and positive regulation of transcription initiation by RNA polymerase II. Predicted to be part of SAGA complex; transcription factor TFIID complex; and transcription factor TFTC complex. Predicted to be active in nucleus. Orthologous to human TAF12 (TATA-box binding protein associated factor 12); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC682902; similar to Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20); TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor; transcription initiation factor TFIID subunit 12
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85149,756,826 - 149,772,886 (+)NCBIGRCr8
mRatBN7.25144,472,816 - 144,490,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5144,472,841 - 144,488,849 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5147,172,810 - 147,188,198 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05148,942,655 - 148,958,096 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05148,931,015 - 148,945,727 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05150,459,701 - 150,476,521 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5150,459,713 - 150,475,186 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05154,126,851 - 154,143,964 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5142,905,400 - 142,920,328 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Taf12Rat1,2-dimethylhydrazine multiple interactionsISOTaf12 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TAF12 mRNACTDPMID:22206623
Taf12Rat17alpha-ethynylestradiol affects expressionISOTaf12 (Mus musculus)6480464Ethinyl Estradiol affects the expression of TAF12 mRNACTDPMID:17555576
Taf12Rat17alpha-ethynylestradiol multiple interactionsISOTaf12 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TAF12 mRNACTDPMID:17942748
Taf12Rat17alpha-ethynylestradiol increases expressionISOTaf12 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of TAF12 mRNACTDPMID:17942748
Taf12Rat17beta-estradiol increases expressionISOTAF12 (Homo sapiens)6480464Estradiol results in increased expression of TAF12 mRNACTDPMID:19167446
Taf12Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOTaf12 (Mus musculus)64804642 more ...CTDPMID:30294300
Taf12Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOTaf12 (Mus musculus)64804642 more ...CTDPMID:31388691
Taf12Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOTAF12 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of TAF12 mRNACTDPMID:21496263
Taf12Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of TAF12 mRNACTDPMID:33387578
Taf12Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOTaf12 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of TAF12 mRNACTDPMID:21570461
Taf12Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOTaf12 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of TAF12 mRNACTDPMID:17942748 and PMID:21496263
Taf12Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOTaf12 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TAF12 mRNACTDPMID:17942748
Taf12Rat2-methylcholine affects expressionISOTAF12 (Homo sapiens)6480464beta-methylcholine affects the expression of TAF12 mRNACTDPMID:21179406
Taf12Rat2-palmitoylglycerol increases expressionISOTAF12 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of TAF12 mRNACTDPMID:37199045
Taf12Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOTAF12 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TAF12 mRNACTDPMID:28628672
Taf12Rat4,4'-diaminodiphenylmethane decreases expressionISOTaf12 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of TAF12 mRNACTDPMID:18648102
Taf12Rataflatoxin B1 increases expressionISOTAF12 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of TAF12 mRNACTDPMID:27153756
Taf12Rataristolochic acid A increases expressionISOTAF12 (Homo sapiens)6480464aristolochic acid I results in increased expression of TAF12 mRNACTDPMID:33212167
Taf12Ratbenzo[a]pyrene increases expressionISOTaf12 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of TAF12 mRNACTDPMID:22228805
Taf12Ratbenzo[a]pyrene affects methylationISOTAF12 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of TAF12 3' UTRCTDPMID:27901495

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Biological Process
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Object Symbol
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Evidence
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Reference
Notes
Source
Original Reference(s)
Taf12Ratbiological_process  ND 159840712/2014: no relevant rat dataRGD 
Taf12RatDNA-templated transcription initiation involved_inISOTAF12 (Homo sapiens)1624291 PMID:9603525RGDPMID:9603525
Taf12RatDNA-templated transcription initiation involved_inIEAInterPro:IPR0032281600115GO_REF:0000002InterProGO_REF:0000002
Taf12RatDNA-templated transcription initiation involved_inIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12RatmRNA transcription by RNA polymerase II involved_inISOTAF12 (Homo sapiens)1624291 PMID:17884155RGDPMID:17884155
Taf12RatmRNA transcription by RNA polymerase II involved_inIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12Ratpositive regulation of transcription by RNA polymerase II involved_inISOTAF12 (Homo sapiens)1624291 PMID:17264123RGDPMID:17264123
Taf12Ratpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12Ratpositive regulation of transcription initiation by RNA polymerase II involved_inISOTAF12 (Homo sapiens)1624291 PMID:17884155RGDPMID:17884155
Taf12Ratpositive regulation of transcription initiation by RNA polymerase II involved_inIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12Ratregulation of transcription by RNA polymerase II involved_inISOTAF12 (Homo sapiens)1624291 PMID:9603525RGDPMID:9603525
Taf12Ratregulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12RatRNA polymerase II preinitiation complex assembly involved_inISOTAF12 (Homo sapiens)1624291 PMID:27007846RGDPMID:27007846
Taf12RatRNA polymerase II preinitiation complex assembly involved_inIBAPANTHER:PTN000262707 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Taf12RatRNA polymerase II preinitiation complex assembly involved_inIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12Rattranscription initiation at RNA polymerase II promoter involved_inISOTAF12 (Homo sapiens)1624291 PMID:9603525RGDPMID:9603525
Taf12Rattranscription initiation at RNA polymerase II promoter involved_inIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Object Symbol
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Reference
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Source
Original Reference(s)
Taf12Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Taf12Ratnucleus located_inISOTaf12 (Mus musculus)1624291 PMID:18722179 and PMID:22323595RGDPMID:18722179 and PMID:22323595
Taf12Ratnucleus located_inISOTAF12 (Homo sapiens)1624291 PMID:11564863 and PMID:23332750RGDPMID:11564863 and PMID:23332750
Taf12Ratnucleus located_inIEAARBA:ARBA000263301600115GO_REF:0000117UniProtGO_REF:0000117
Taf12Ratnucleus is_active_inISOTaf12 (Mus musculus)1624291PR:P07903 PMID:22323595RGDPMID:22323595
Taf12Ratnucleus located_inIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12RatSAGA complex part_ofISOTAF12 (Homo sapiens) more ...1624291 PMID:9674425RGDPMID:9674425
Taf12RatSAGA complex part_ofISOTaf12 (Mus musculus)1624291 PMID:19103755RGDPMID:19103755
Taf12RatSAGA complex part_ofIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12RatSAGA complex part_ofIEAInterPro:IPR0377941600115GO_REF:0000002InterProGO_REF:0000002
Taf12RatSAGA complex part_ofISOTAF12 (Homo sapiens)1624291 PMID:11564863RGDPMID:11564863
Taf12Rattranscription factor TFIID complex part_ofISOTAF12 (Homo sapiens)1624291 PMID:14580349 more ...RGDPMID:14580349 more ...
Taf12Rattranscription factor TFIID complex part_ofIBAFB:FBgn0011290 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Taf12Rattranscription factor TFIID complex part_ofIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12Rattranscription factor TFIID complex part_ofIEAInterPro:IPR003228 and InterPro:IPR0377941600115GO_REF:0000002InterProGO_REF:0000002
Taf12Rattranscription factor TFTC complex part_ofISOTAF12 (Homo sapiens)1624291 PMID:9603525RGDPMID:9603525
Taf12Rattranscription factor TFTC complex part_ofIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
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Object Symbol
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Reference
Notes
Source
Original Reference(s)
Taf12RatDNA binding enablesISOTAF12 (Homo sapiens)1624291 PMID:15601843RGDPMID:15601843
Taf12RatDNA binding enablesISOTaf12 (Mus musculus)1624291 PMID:18722179RGDPMID:18722179
Taf12RatDNA binding enablesIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12RatDNA binding enablesIBAMGI:1913714 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Taf12RatDNA-binding transcription factor binding enablesISOTAF12 (Homo sapiens)1624291UniProtKB:P17544 and PMID:17264123RGDPMID:17264123
Taf12RatDNA-binding transcription factor binding enablesIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12Ratprotein binding enablesISOTAF12 (Homo sapiens) and UniProtKB:Q16514-11624291UniProtKB:O00268 and PMID:23292512RGDPMID:23292512
Taf12Ratprotein binding enablesISOTaf12 (Mus musculus)1624291PR:P07903 more ...RGDPMID:16481476 and PMID:22323595
Taf12Ratprotein binding enablesISOTAF12 (Homo sapiens)1624291UniProtKB:O00268 more ...RGDPMID:11438666 more ...
Taf12Ratprotein heterodimerization activity enablesIEAInterPro:IPR0090721600115GO_REF:0000002InterProGO_REF:0000002
Taf12RatRNA polymerase II general transcription initiation factor activity contributes_toISOTAF12 (Homo sapiens)1624291 PMID:9603525RGDPMID:9603525
Taf12RatRNA polymerase II general transcription initiation factor activity contributes_toIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
Taf12RatTBP-class protein binding enablesIBAPANTHER:PTN000262707 and SGD:S0000025521600115GO_REF:0000033GO_CentralGO_REF:0000033
Taf12Rattranscription coactivator activity enablesISOTAF12 (Homo sapiens)1624291 PMID:11564863 and PMID:17264123RGDPMID:11564863 and PMID:17264123
Taf12Rattranscription coactivator activity enablesIEAUniProtKB:Q16514 and ensembl:ENSP000003629301600115GO_REF:0000107EnsemblGO_REF:0000107
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RGD Manual Annotations


  

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. TFIIB-related factors in RNA polymerase I transcription. Knutson BA and Hahn S, Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):265-73. doi: 10.1016/j.bbagrm.2012.08.003. Epub 2012 Aug 30.
3. Structural bioinformatics of the general transcription factor TFIID. Malkowska M, etal., Biochimie. 2013 Apr;95(4):680-91. doi: 10.1016/j.biochi.2012.10.024. Epub 2012 Nov 9.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation. Schneider DA Gene. 2012 Feb 10;493(2):176-84. doi: 10.1016/j.gene.2011.08.006. Epub 2011 Aug 26.
8. ATAC-king the complexity of SAGA during evolution. Spedale G, etal., Genes Dev. 2012 Mar 15;26(6):527-41. doi: 10.1101/gad.184705.111.
PMID:9603525   PMID:9674425   PMID:11564863   PMID:12477932   PMID:14580349   PMID:15601843   PMID:15735663   PMID:17264123   PMID:18722179   PMID:19103755   PMID:22323595  



Taf12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85149,756,826 - 149,772,886 (+)NCBIGRCr8
mRatBN7.25144,472,816 - 144,490,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5144,472,841 - 144,488,849 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5147,172,810 - 147,188,198 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05148,942,655 - 148,958,096 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05148,931,015 - 148,945,727 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05150,459,701 - 150,476,521 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5150,459,713 - 150,475,186 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05154,126,851 - 154,143,964 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5142,905,400 - 142,920,328 (+)NCBICelera
Cytogenetic Map5q36NCBI
TAF12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,602,850 - 28,648,269 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,587,829 - 28,648,291 (-)EnsemblGRCh38hg38GRCh38
GRCh37128,929,362 - 28,969,579 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,802,200 - 28,842,172 (-)NCBINCBI36Build 36hg18NCBI36
Build 34128,750,228 - 28,790,201NCBI
Celera127,325,365 - 27,365,501 (-)NCBICelera
Cytogenetic Map1p35.3NCBI
HuRef127,182,618 - 27,222,688 (-)NCBIHuRef
CHM1_1129,045,214 - 29,085,178 (-)NCBICHM1_1
T2T-CHM13v2.0128,444,812 - 28,490,693 (-)NCBIT2T-CHM13v2.0
Taf12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394132,001,667 - 132,020,640 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4132,001,686 - 132,023,077 (+)EnsemblGRCm39 Ensembl
GRCm384132,274,355 - 132,293,329 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4132,274,375 - 132,295,766 (+)EnsemblGRCm38mm10GRCm38
MGSCv374131,830,290 - 131,849,244 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364131,546,489 - 131,565,403 (+)NCBIMGSCv36mm8
Celera4130,435,455 - 130,454,533 (+)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map465.09NCBI
TAF12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21198,199,107 - 198,239,106 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11197,318,260 - 197,358,257 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,874,675 - 27,914,672 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1128,907,540 - 28,948,322 (-)NCBIpanpan1.1PanPan1.1panPan2
TAF12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,865,274 - 71,898,236 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,865,289 - 71,898,236 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha268,442,106 - 68,475,051 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0272,424,252 - 72,457,215 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl272,424,264 - 72,457,215 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1269,252,893 - 69,285,838 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0270,260,614 - 70,293,571 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0271,258,668 - 71,291,609 (+)NCBIUU_Cfam_GSD_1.0
Taf12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505846,870,722 - 46,894,620 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647412,693,018 - 12,720,136 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647412,695,508 - 12,719,384 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAF12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl685,618,691 - 85,643,075 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1685,618,679 - 85,643,087 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2679,432,412 - 79,441,136 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TAF12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120104,164,912 - 104,199,925 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20104,164,907 - 104,200,272 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603312,313,419 - 12,350,679 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Taf12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476412,396,938 - 12,445,681 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476412,401,152 - 12,444,978 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Taf12
110 total Variants

Predicted Target Of
Summary Value
Count of predictions:77
Count of miRNA genes:66
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000074251
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat

1 to 10 of 42 rows
RH128062  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25144,487,461 - 144,487,668 (+)MAPPERmRatBN7.2
Rnor_6.05150,473,684 - 150,473,890NCBIRnor6.0
Rnor_5.05154,141,127 - 154,141,333UniSTSRnor5.0
Celera5142,920,008 - 142,920,214UniSTS
RH 3.4 Map5965.1UniSTS
RH139476  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map8859.2UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000074251   ⟹   ENSRNOP00000066252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5144,472,880 - 144,488,849 (+)Ensembl
Rnor_6.0 Ensembl5150,459,745 - 150,474,004 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000081681   ⟹   ENSRNOP00000070933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5144,472,841 - 144,488,849 (+)Ensembl
Rnor_6.0 Ensembl5150,459,713 - 150,475,186 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097331   ⟹   ENSRNOP00000090404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5144,473,163 - 144,488,849 (+)Ensembl
RefSeq Acc Id: NM_001115036   ⟹   NP_001108508
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,756,894 - 149,771,804 (+)NCBI
mRatBN7.25144,472,871 - 144,487,782 (+)NCBI
Rnor_6.05150,459,745 - 150,474,004 (+)NCBI
Rnor_5.05154,126,851 - 154,143,964 (+)NCBI
Celera5142,905,400 - 142,920,328 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239067   ⟹   XP_006239129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,756,826 - 149,772,886 (+)NCBI
mRatBN7.25144,472,816 - 144,490,299 (+)NCBI
Rnor_6.05150,459,701 - 150,476,521 (+)NCBI
Rnor_5.05154,126,851 - 154,143,964 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239068   ⟹   XP_006239130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,757,015 - 149,772,886 (+)NCBI
mRatBN7.25144,472,851 - 144,490,299 (+)NCBI
Rnor_6.05150,459,701 - 150,476,521 (+)NCBI
Rnor_5.05154,126,851 - 154,143,964 (+)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001108508 (Get FASTA)   NCBI Sequence Viewer  
  XP_006239129 (Get FASTA)   NCBI Sequence Viewer  
  XP_006239130 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58611 (Get FASTA)   NCBI Sequence Viewer  
  EDL80620 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066252.1
  ENSRNOP00000070933
  ENSRNOP00000070933.1
  ENSRNOP00000090404.1
1 to 9 of 9 rows
RefSeq Acc Id: NP_001108508   ⟸   NM_001115036
- UniProtKB: B0BMY3 (UniProtKB/TrEMBL),   M0R9S2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239129   ⟸   XM_006239067
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JZ70 (UniProtKB/TrEMBL),   A0A8I6ABQ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239130   ⟸   XM_006239068
- Peptide Label: isoform X2
- UniProtKB: B0BMY3 (UniProtKB/TrEMBL),   M0R9S2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070933   ⟸   ENSRNOT00000081681
Ensembl Acc Id: ENSRNOP00000066252   ⟸   ENSRNOT00000074251
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JZ70-F1-model_v2 AlphaFold A0A0G2JZ70 1-213 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694094
Promoter ID:EPDNEW_R4617
Type:initiation region
Name:Taf12_1
Description:TATA-box binding protein associated factor 12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05150,459,745 - 150,459,805EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-39708 BioCyc
Ensembl Genes ENSRNOG00000048288 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074251.2 UniProtKB/TrEMBL
  ENSRNOT00000081681 ENTREZGENE
  ENSRNOT00000081681.2 UniProtKB/TrEMBL
  ENSRNOT00000097331.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7374180 IMAGE-MGC_LOAD
InterPro Histone-fold UniProtKB/TrEMBL
  TAF12 UniProtKB/TrEMBL
  TFIID_sub UniProtKB/TrEMBL
KEGG Report rno:682902 UniProtKB/TrEMBL
MGC_CLONE MGC:187487 IMAGE-MGC_LOAD
NCBI Gene 682902 ENTREZGENE
PANTHER PTHR12264 UniProtKB/TrEMBL
  TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 UniProtKB/TrEMBL
Pfam TFIID_20kDa UniProtKB/TrEMBL
PhenoGen Taf12 PhenoGen
RatGTEx ENSRNOG00000048288 RatGTEx
Superfamily-SCOP Histone-fold UniProtKB/TrEMBL
UniProt A0A0G2JZ70 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ABQ9 ENTREZGENE, UniProtKB/TrEMBL
  B0BMY3 ENTREZGENE, UniProtKB/TrEMBL
  M0R9S2 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-14 Taf12  TATA-box binding protein associated factor 12  Taf12  TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-04-14 Taf12  TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor  LOC682902  similar to Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC682902  similar to Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20)      Symbol and Name status set to provisional 70820 PROVISIONAL