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Gene: Marcksl1 (MARCKS-like 1) Rattus norvegicus
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Symbol: Marcksl1
Name: MARCKS-like 1
RGD ID: 621197
Description: Exhibits voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels. Predicted to be involved in actin filament organization; central nervous system development; and positive regulation of cell population proliferation. Localizes to anchored component of presynaptic membrane and presynaptic cytosol. Biomarker of visual epilepsy. Orthologous to human MARCKSL1 (MARCKS like 1); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; Leishmaniasis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: brain protein F52; F52; LOC100911122; mac-MARCKS; macMARCKS; macrophage myristoylated alanine-rich C kinase substrate; MARCKS-like protein; MARCKS-like protein 1; MARCKS-related protein; MARCKS-related protein-like; MGC93399; Mlp; myristoylated alanine-rich C kinase substrate
Orthologs:
Homo sapiens (human) : MARCKSL1 (MARCKS like 1)  HGNC  Alliance
Mus musculus (house mouse) : Marcksl1 (MARCKS-like 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Marcksl1 (MARCKS like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MARCKSL1 (MARCKS like 1)
Canis lupus familiaris (dog) : MARCKSL1 (MARCKS like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101964231 (uncharacterized LOC101964231)
Sus scrofa (pig) : MARCKSL1 (MARCKS like 1)
Chlorocebus sabaeus (African green monkey) : MARCKSL1 (MARCKS like 1)
Heterocephalus glaber (naked mole-rat) : Marcksl1 (MARCKS like 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05147,714,163 - 147,716,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5147,714,163 - 147,716,485 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0186,034,161 - 86,035,603 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45148,669,499 - 148,672,337NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15148,679,537 - 148,682,375NCBI
Celera5140,326,977 - 140,329,076 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Marcksl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621197
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.