Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TCEA3 mRNA] | CTD | PMID:31150632 | 1,1-dichloroethene | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of TCEA3 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | increases expression | ISO | Tcea3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of TCEA3 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of TCEA3 mRNA] | CTD | PMID:22206623 | 17beta-estradiol | affects expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Estradiol affects the expression of TCEA3 mRNA | CTD | PMID:22574217 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of TCEA3 mRNA | CTD | PMID:32145629 | 17beta-estradiol | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Estradiol results in increased expression of TCEA3 mRNA | CTD | PMID:17121429 | 17beta-estradiol | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Estradiol results in decreased expression of TCEA3 mRNA | CTD | PMID:19484750 | 17beta-estradiol | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of TCEA3 mRNA and [Estradiol co-treated with TGFB1 protein] results in decreased expression of TCEA3 mRNA | CTD | PMID:20660070 and PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TCEA3 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TCEA3 mRNA | CTD | PMID:26290441 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tcea3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TCEA3 mRNA | CTD | PMID:21570461 and PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TCEA3 mRNA | CTD | PMID:18796159 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TCEA3 mRNA | CTD | PMID:20106945 and PMID:21632981 | 2,4,6-trinitrotoluene | affects expression | EXP | | 6480464 | Trinitrotoluene affects the expression of TCEA3 mRNA | CTD | PMID:21346803 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of TCEA3 mRNA | CTD | PMID:21346803 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of TCEA3 mRNA | CTD | PMID:25172293 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Tcea3 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of TCEA3 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | Tcea3 (Mus musculus) | 6480464 | bisphenol S results in increased expression of TCEA3 mRNA | CTD | PMID:30951980 | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of TCEA3 mRNA | CTD | PMID:21346803 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TCEA3 mRNA | CTD | PMID:24780913 and PMID:30047161 | aflatoxin B1 | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of TCEA3 mRNA | CTD | PMID:27153756 | aflatoxin B1 | decreases methylation | ISO | TCEA3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TCEA3 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Tretinoin results in decreased expression of TCEA3 mRNA | CTD | PMID:16604517 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of TCEA3 mRNA | CTD | PMID:30047161 | Aroclor 1254 | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of TCEA3 mRNA | CTD | PMID:23650126 | arsane | affects methylation | ISO | TCEA3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TCEA3 gene | CTD | PMID:25304211 | arsane | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TCEA3 mRNA | CTD | PMID:32525701 | arsenic atom | affects methylation | ISO | TCEA3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TCEA3 gene | CTD | PMID:25304211 | arsenic atom | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TCEA3 mRNA | CTD | PMID:32525701 | arsenous acid | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TCEA3 mRNA | CTD | PMID:20458559 | azathioprine | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Azathioprine results in decreased expression of TCEA3 mRNA | CTD | PMID:22623647 | benzo[a]pyrene | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TCEA3 mRNA | CTD | PMID:26238291 | benzo[a]pyrene | affects methylation | ISO | TCEA3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TCEA3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | TCEA3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of TCEA3 exon | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TCEA3 mRNA | CTD | PMID:27858113 | benzo[b]fluoranthene | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TCEA3 mRNA | CTD | PMID:27858113 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TCEA3 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol A | increases expression | ISO | Tcea3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TCEA3 mRNA | CTD | PMID:32156529 | bisphenol A | affects expression | ISO | TCEA3 (Homo sapiens) | 6480464 | bisphenol A affects the expression of TCEA3 mRNA | CTD | PMID:30903817 | bisphenol A | increases methylation | ISO | Tcea3 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of TCEA3 promoter | CTD | PMID:27312807 | bisphenol A | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of TCEA3 mRNA | CTD | PMID:27685785 | bisphenol F | increases expression | ISO | Tcea3 (Mus musculus) | 6480464 | bisphenol F results in increased expression of TCEA3 mRNA | CTD | PMID:30951980 | bromobenzene | decreases expression | EXP | | 6480464 | bromobenzene results in decreased expression of TCEA3 mRNA | CTD | PMID:32479839 | Butylparaben | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | butylparaben results in increased expression of TCEA3 mRNA | CTD | PMID:17121429 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of TCEA3 mRNA | CTD | PMID:19167457 | caffeine | decreases phosphorylation | ISO | TCEA3 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of TCEA3 protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | chrysene | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TCEA3 mRNA | CTD | PMID:27858113 | cisplatin | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TCEA3 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TCEA3 mRNA | CTD | PMID:27392435 | clofibrate | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of TCEA3 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TCEA3 mRNA] | CTD | PMID:17585979 | copper atom | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TCEA3 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TCEA3 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of TCEA3 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of TCEA3 mRNA | CTD | PMID:19770486 | cyclosporin A | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TCEA3 mRNA | CTD | PMID:20106945 and PMID:25562108 | diarsenic trioxide | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TCEA3 mRNA | CTD | PMID:20458559 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of TCEA3 mRNA | CTD | PMID:21266533 | dioxygen | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of TCEA3 mRNA | CTD | PMID:26516004 | dioxygen | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TCEA3 mRNA | CTD | PMID:30529165 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of TCEA3 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | entinostat results in increased expression of TCEA3 mRNA | CTD | PMID:27188386 | folic acid | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of TCEA3 mRNA] | CTD | PMID:22206623 | FR900359 | affects phosphorylation | ISO | TCEA3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TCEA3 protein | CTD | PMID:37730182 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TCEA3 mRNA | CTD | PMID:26194646 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of TCEA3 mRNA | CTD | PMID:22061828 and PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of TCEA3 mRNA | CTD | PMID:24136188 | graphite | affects expression | EXP | | 6480464 | Graphite affects the expression of TCEA3 mRNA | CTD | PMID:29933104 | inulin | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TCEA3 mRNA | CTD | PMID:36331819 | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of TCEA3 mRNA | CTD | PMID:24136188 | lipopolysaccharide | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of TCEA3 mRNA | CTD | PMID:35811015 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of TCEA3 mRNA | CTD | PMID:30047161 | N-nitrosodiethylamine | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Diethylnitrosamine results in decreased expression of TCEA3 mRNA | CTD | PMID:21527772 | N-Nitrosopyrrolidine | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of TCEA3 mRNA | CTD | PMID:32234424 | nickel sulfate | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of TCEA3 mRNA | CTD | PMID:22714537 | p-toluidine | increases expression | EXP | | 6480464 | 4-toluidine results in increased expression of TCEA3 mRNA | CTD | PMID:27638505 | paracetamol | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of TCEA3 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TCEA3 mRNA] | CTD | PMID:17585979 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TCEA3 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TCEA3 mRNA | CTD | PMID:22230336 | paracetamol | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of TCEA3 mRNA | CTD | PMID:21420995 | paracetamol | affects expression | ISO | Tcea3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TCEA3 mRNA | CTD | PMID:17562736 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of TCEA3 mRNA | CTD | PMID:32680482 | perfluorohexanesulfonic acid | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of TCEA3 mRNA | CTD | PMID:25812627 | perfluorononanoic acid | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of TCEA3 mRNA | CTD | PMID:25812627 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TCEA3 mRNA | CTD | PMID:36331819 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of TCEA3 mRNA | CTD | PMID:25812627 | perfluorooctanoic acid | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of TCEA3 mRNA | CTD | PMID:25812627 | phenobarbital | affects expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of TCEA3 mRNA | CTD | PMID:19159669 | pirinixic acid | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TCEA3 mRNA | CTD | PMID:18445702 | pirinixic acid | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TCEA3 mRNA | CTD | PMID:19710929 | potassium dichromate | increases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of TCEA3 mRNA | CTD | PMID:23608068 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of TCEA3 mRNA | CTD | PMID:28903501 | progesterone | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of TCEA3 mRNA | CTD | PMID:20660070 | propanal | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of TCEA3 mRNA | CTD | PMID:26079696 | propiconazole | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | propiconazole results in decreased expression of TCEA3 mRNA | CTD | PMID:21278054 | rotenone | affects expression | EXP | | 6480464 | Rotenone affects the expression of TCEA3 mRNA | CTD | PMID:28374803 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of TCEA3 mRNA | CTD | PMID:35811015 | sodium arsenate | multiple interactions | ISO | TCEA3 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TCEA3 mRNA | CTD | PMID:32525701 | sodium arsenite | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TCEA3 mRNA | CTD | PMID:37682722 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of TCEA3 mRNA | CTD | PMID:30047161 | tetrachloromethane | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of TCEA3 mRNA | CTD | PMID:27339419 and PMID:31919559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TCEA3 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TCEA3 mRNA | CTD | PMID:31150632 | tetraphene | multiple interactions | ISO | Tcea3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TCEA3 mRNA | CTD | PMID:27858113 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TCEA3 mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of TCEA3 mRNA | CTD | PMID:23557971 | triclosan | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of TCEA3 mRNA | CTD | PMID:30510588 | Triptolide | decreases expression | ISO | Tcea3 (Mus musculus) | 6480464 | triptolide results in decreased expression of TCEA3 mRNA | CTD | PMID:32835833 | tunicamycin | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of TCEA3 mRNA | CTD | PMID:29453283 | urethane | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of TCEA3 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Tcea3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of TCEA3 mRNA | CTD | PMID:17292431 | valproic acid | increases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TCEA3 mRNA | CTD | PMID:23179753 | valproic acid | decreases expression | ISO | TCEA3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TCEA3 mRNA | CTD | PMID:29154799 | vancomycin | increases expression | ISO | Tcea3 (Mus musculus) | 6480464 | Vancomycin results in increased expression of TCEA3 mRNA | CTD | PMID:18930951 | |