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Gene: Slc66a1 (solute carrier family 66 member 1) Rattus norvegicus

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Symbol:

Slc66a1

Name:

solute carrier family 66 member 1

RGD ID:

1311627

Description:

Enables basic amino acid transmembrane transporter activity. Involved in intracellular amino acid homeostasis. Located in lysosomal membrane. Orthologous to human SLC66A1 (solute carrier family 66 member 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; aflatoxin B1.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC362642; lysosomal amino acid transporter 1 homolog; PQ loop repeat containing 2; PQ-loop repeat-containing protein 2; Pqlc2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC66A1 (solute carrier family 66 member 1)	HGNC	Ensembl, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Slc66a1 (solute carrier family 66 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc66a1 (solute carrier family 66 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC66A1 (solute carrier family 66 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC66A1 (solute carrier family 66 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc66a1 (solute carrier family 66 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC66A1 (solute carrier family 66 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC66A1 (solute carrier family 66 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc66a1 (solute carrier family 66 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SLC66A1 (solute carrier family 66 member 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc66a1 (solute carrier family 66 member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pqlc2 (PQ loop repeat containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	laat-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RTC2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YPQ1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YPQ2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	XB5947741 [provisional]	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	slc66a1l	Alliance	DIOPT (InParanoid\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mgc69309	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	156,821,084 - 156,835,558 (-)	NCBI		GRCr8
mRatBN7.2	5	151,537,870 - 151,552,259 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	151,542,376 - 151,552,259 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	154,240,875 - 154,250,750 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	156,015,223 - 156,025,098 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	155,996,194 - 156,006,086 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	157,744,945 - 157,759,370 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	157,745,490 - 157,759,322 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	161,485,179 - 161,499,508 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	158,087,137 - 158,097,572 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	158,097,687 - 158,106,359 (-)	NCBI
Celera	5	149,924,109 - 149,930,042 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-hydroxy-3-methylglutaryl-CoA lyase deficiency (ISO)

chromosome 1p36 deletion syndrome (ISO)

congenital disorder of glycosylation Ir (ISO)

cystinosis (ISO)

hyperprolinemia type 2 (ISO)

Parkinson's disease 6 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

(2,4,5-trichlorophenoxy)acetic acid (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (EXP,ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

clofibrate (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

indole-3-methanol (EXP)

isoflurane (ISO)

L-methionine (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methamphetamine (EXP)

methyl methanesulfonate (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

SCH 23390 (EXP)

sodium arsenite (ISO)

Soman (EXP)

testosterone (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amino acid transport (IEA)

intracellular amino acid homeostasis (IEA,IMP,ISO)

L-arginine transmembrane transport (IEA,ISO)

L-histidine transmembrane transport (IEA,ISO)

L-lysine transmembrane transport (IEA,ISO)

lysine transport (IEA,ISO)

Cellular Component

intracellular membrane-bounded organelle (IEA,ISO)

lysosomal membrane (IBA,IDA,IEA,ISO)

lysosome (IEA)

membrane (IEA)

organelle membrane (IEA,ISO)

Molecular Function

basic amino acid transmembrane transporter activity (IDA)

L-arginine transmembrane transporter activity (IEA,ISO)

L-histidine transmembrane transporter activity (IEA,ISO)

L-lysine transmembrane transporter activity (IBA,IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapy.	Jezegou A, etal., Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):E3434-43. doi: 10.1073/pnas.1211198109. Epub 2012 Nov 20.
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:22822152

Genomics

Comparative Map Data

Slc66a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	156,821,084 - 156,835,558 (-)	NCBI		GRCr8
mRatBN7.2	5	151,537,870 - 151,552,259 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	151,542,376 - 151,552,259 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	154,240,875 - 154,250,750 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	156,015,223 - 156,025,098 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	155,996,194 - 156,006,086 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	157,744,945 - 157,759,370 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	157,745,490 - 157,759,322 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	161,485,179 - 161,499,508 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	158,087,137 - 158,097,572 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	158,097,687 - 158,106,359 (-)	NCBI
Celera	5	149,924,109 - 149,930,042 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

SLC66A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	19,312,326 - 19,334,463 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	19,312,326 - 19,329,300 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	19,638,820 - 19,658,922 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	19,511,327 - 19,528,381 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	19,384,125 - 19,404,227	NCBI
Celera	1	17,965,741 - 17,982,808 (+)	NCBI		Celera
Cytogenetic Map	1	p36.13	NCBI
HuRef	1	17,885,165 - 17,902,100 (+)	NCBI		HuRef
CHM1_1	1	19,748,043 - 19,765,096 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	19,135,861 - 19,158,016 (+)	NCBI		T2T-CHM13v2.0

Slc66a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	139,021,341 - 139,038,025 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	139,021,340 - 139,038,019 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	139,294,030 - 139,310,760 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	139,294,029 - 139,310,708 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	138,853,920 - 138,866,615 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	138,570,606 - 138,582,754 (-)	NCBI		MGSCv36	mm8
Celera	4	141,084,526 - 141,097,214 (-)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	70.63	NCBI

Slc66a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	16,770 - 26,189 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	17,459 - 22,259 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC66A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	207,786,098 - 207,803,143 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	206,902,431 - 206,919,927 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	18,270,882 - 18,288,387 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	19,317,244 - 19,333,926 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	19,317,244 - 19,333,926 (+)	Ensembl	panpan1.1		panPan2

SLC66A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	79,318,200 - 79,334,047 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	79,318,345 - 79,320,885 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	75,831,339 - 75,848,952 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	79,940,414 - 79,956,745 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	79,939,336 - 79,956,723 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	76,701,369 - 76,717,652 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	77,711,001 - 77,727,285 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	78,780,655 - 78,798,382 (-)	NCBI		UU_Cfam_GSD_1.0

Slc66a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	39,748,339 - 39,763,537 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	5,576,507 - 5,590,279 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	5,573,175 - 5,588,319 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC66A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	77,761,782 - 77,778,571 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	77,761,861 - 77,778,570 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	71,823,957 - 71,840,716 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC66A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	113,217,379 - 113,234,176 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	113,216,715 - 113,233,964 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	2,925,128 - 2,941,705 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc66a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	4,457,156 - 4,465,109 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	4,455,843 - 4,466,413 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc66a1
81 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	100
Count of miRNA genes:	86
Interacting mature miRNAs:	93
Transcripts:	ENSRNOT00000023896
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
2302369	Scl60	Serum cholesterol level QTL 60	3.13		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	143608201	161165651	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	144358090	157869054	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	151113452	164465185	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	143799107	158428037	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	151113452	166875058	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	144377876	161317411	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
1298090	Bp155	Blood pressure QTL 155	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	151006154	161165494	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat

Markers in Region

AI175351

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	151,542,434 - 151,542,600 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	157,749,510 - 157,749,675	NCBI	Rnor6.0
Rnor_5.0	5	161,489,744 - 161,489,909	UniSTS	Rnor5.0
RGSC_v3.4	5	158,087,708 - 158,087,873	UniSTS	RGSC3.4
Celera	5	149,922,648 - 149,922,813	UniSTS
RH 3.4 Map	5	1036.4	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001399232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_174173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239239	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC158607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000023896 ⟹ ENSRNOP00000023896

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,542,376 - 151,552,259 (-)	Ensembl
Rnor_6.0 Ensembl	5	157,749,457 - 157,759,322 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083341 ⟹ ENSRNOP00000072028

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	157,745,490 - 157,758,084 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099105 ⟹ ENSRNOP00000077592

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,542,382 - 151,550,124 (-)	Ensembl

RefSeq Acc Id:

NM_001399232 ⟹ NP_001386161

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,825,590 - 156,835,473 (-)	NCBI
mRatBN7.2	5	151,542,376 - 151,552,259 (-)	NCBI

RefSeq Acc Id:

NM_001399233 ⟹ NP_001386162

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,825,590 - 156,835,473 (-)	NCBI
mRatBN7.2	5	151,542,376 - 151,552,259 (-)	NCBI

RefSeq Acc Id:

NM_001399234 ⟹ NP_001386163

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,825,590 - 156,835,473 (-)	NCBI
mRatBN7.2	5	151,542,376 - 151,552,259 (-)	NCBI

RefSeq Acc Id:

NR_174173

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,825,590 - 156,835,473 (-)	NCBI
mRatBN7.2	5	151,542,376 - 151,552,259 (-)	NCBI

RefSeq Acc Id:

XM_006239239 ⟹ XP_006239301

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,821,084 - 156,835,464 (-)	NCBI
mRatBN7.2	5	151,537,870 - 151,552,205 (-)	NCBI
Rnor_6.0	5	157,744,945 - 157,758,713 (-)	NCBI
Rnor_5.0	5	161,485,179 - 161,499,508 (-)	NCBI

Sequence:

show sequence

GAAACCCTGTCTCAAACAACCCCATCCCCACCGGCCCCGAAAAGAAACAAAGAAGTGTGTAGTT
TCAGGTCTTGTTCACTTCGTGTATACTCCATGCCATGTGATCCAGGGGACTACAGCAAGAACAG
ATTACTGTTGACTGTGCTAGATGGGCTTTGCTGGGAAGCACCTCCCTGGCTGTGCTTGGAGTTG
GAGAGGAAATAGGTGTTGTAGGAGATTGCCTCCCTGGTCAGCCTTTCTGGAGAATGTTATTAGC
CCCAGTTCATAGACAGGGTCAGACAGGCAGACTCGCAGAAGGAGTCCAATAGGATGTGTGTCGG
ATAAACGAGAAGGCTTCTTAGGGTACAGTCTTACCTAGACTGCAAATTGGGGTGCCAGGTATTG
CTCCCCAAATTGGCTATGCCACTATCATCCGCACCAGCCACTAAGACCAGGAAAGAACCTTCCA
TCTATCCTATGTCCCATGCTGGAGCTACCACAGTAAGCTAGCCAGTGACCGGAGGCACCCTTAC
CCCGACCCGCTGGCTGAGTCTGGGCGCCTGAGAGGCTGACTTAGGACTGAGAGTCTGGGTGTCC
TGAAGAAACGAGCTGACTTGCTTCCTCTCCCTGCCCTGCTCACTGCAAGCTCAGCAGTCCGGAT
CCAGCCTAAGCTTTGTGAAGAGTCCAGGCCTCACTGGCCTAAGTAGGAACTAAGGTTGTCACAT
ACTCAGAGTGACCACAATAGGAACTCTGTGCAGGTGGCAAGGAACTGAGAGGACCCCTTTCTTC
CTGCTCTTCCACCCAGCCATACTCTGGCTTGGGCTGTGGCTTCCTTGCAGCCATGGTCTGGAGG
ACACTGGTCGCCAGCAACTTTTCCACCTGCCCCAATGGCTCTATCCAGTGGATCTGGGATGTGT
TTGGTGAATGTGCCCAGGATGGCTGGGATGAGGCCAGCGTGGCCCTGGGCTTGGTCTCCATTTT
CTGCTTTGCTGCGTCTACCTTTCCCCAGTACATCAAAGCCTGCAAGACAGGCAACATGGACCAG
GCCCTGTCACTGTGGTTCCTGCTGGGCTGGATCGGTGGAGACTCCTGCAACCTCATTGGTTCCT
TTCTGGCAGACCAGCTACCCCTGCAGACCTACACGGCTGTGTATTATGTCCTGGCCGACCTTTT
GATGCTGACACTGTACTTCCACTACAAGTTCAAGAAGCAGCCCTCTCTGTTGTCTGCCCCAATC
AATTCTGTGCTCTTGTTCATCTTGGGGACGGTGTGCATCACACCACTGTTGAGCAGCACTGATC
CTGTGGCTGTCCCCAGGGAAGGCTTCAGGGGGCGGACGCTCCTGTCTGTGGAGCCAGGCAATAA
GCCCTTCACAAAGAAGGAGGTCGTCGGTTTTGTCATTGGCTCCGCCTCCAGCGTGCTGTACCTG
CTCTCAAGGCTGCCGCAGATTCGCACCAATTTCGTACGGCAGTCAACCCAAGGCATTTCCTACT
CGCTGTTTGCACTGGTGATGCTGGGGAACACGCTATATGGGCTCAGTGTGCTGCTCAAAAACCC
CGAGGTGGGCCAGAGTGAGGGCAGCTATCTGCTGCACCACCTGCCCTGGCTCGTGGGCAGCCTG
GGAGTGCTCCTGCTTGACACCATTATCTCCATCCAGTTCCTGGTGTACAGAAGCCATGATGCTG
ATGCTGCCTCAGAGCGAGAGCCGCTCCTCCCAAGCTGACCCCACAGCTGCCCTCCCAGGAAGGA
GTGATACTGCCGCCACTGGACTGGGCCTAGGAGGTGGCCTGGGACTCTGGGCCTGGCTGCCTCC
CCTCCACACCTGGCCTTCAGACAGGTCTAGAGTTGGCACAGGTCTGGAGTTGGCGTGTGCTATG
CCGGGACATACCTCTCAGGTATATGACAGCTGTCCGAGGAGCCTCTAGGGCACCCCAGAAGACG
GTGTGGCCTCCTCCCAATCAAACTACCTCAATCTGACTATGTACTCCTGGCTACATCATAGCTG
GGGGACCCAGGGTTGTCCCTCTGACTGGGCACAACCTAGTAAATAGTACCTTCCAGCTGGGCCT
GTTTCTGCTGCTCCTTCCCATGGTGCTTGAGGTCTAGGCAGGGATCCAGGGCAAGCCCATCCTG
ATAGGGGGGGCACGTGCAGCCTCCCTGGCCCTTGGCATCCTAACTTGTATCCTTCTGTCCTCTT
GTACACAGACCCTACCTGGTGTGGGACACCAGTGGTCTCTCTGTTCCTGGGGCTCTGGGAGAAG
CAGATAACCAAGGGCAGGCTTTGGTTGAGCATCACCAGAGGCCTGGCATGACCATGTGACCGCC
CCCTCTGTCCTTGCCCAGGCCGTGTAGGGTGAGGCAGCTAGCCCAAAGCGAGGCATGTAGTCAA
GTGTCTCATACAGTCAGAGCTCAGTGATGGTCGCTGAAGTGGAGAAGAGGGGAAGACTGGTGCC
TTTCTGAGGAAGGCAGAGACTAGAAGCACAGGTGGAAAACAAGGCCAGCAGGAGACGGGTGACG
GGGGCAGAGAGGAAGGGAGGAAGATTGGTCTCAGCGGTCTTTGTTACAACACCTTTAGGGGACA
GAGGACCAGCCTCCTCTCCTGCTAGCCTCAGCTTACTGATACATTATTGTAGGTCCAGAAAGTC
AGATGCAGGGCCAGGGGGCTGCCTGCCAGAGACAAACAGGGCAGCCGCCTCAGTGCTTTTTGTA
GCTTCTCTGTCCATAGCTGAGGAGAAGATCCTGGCACAGACCCAGGCAAGGCATATGGTGCTCC
CGGTCCCTGCTCTTAACCCACTGCTGGCTTCAGGTGATCTTTGCAGCTCATGCCGTCCTGGGAC
TTGGCTCTAGGCTAGTTTCCTAGGGCCAGATGGCACCTTTCCAAATCCTGAAGATCTGGGGCCT
CAGTGTGGTACAGGACCCCAGGTGCACGGGCAGGACAACATGAAATGCCAGCCCTGTCTGAGCT
CTCCTGGGTCTGTCAGGCGGAGCGACAACCCTTCATGGGGGAGTCGTGCTTTGCCCACAGGAAT
TCCTGTCTGACAGAGGAGGTGGTCTCAGGAAGGTTGCAGTTCCTCTAAACCTCAGTTCCTCCTC
TCTTCTGGAGGCTCGCTCCAGTACTCCAAGGAGGGGTCAGAGTAGGGAGCTTGCAGAACCTGGT
GGCCTGGTTATTTTATTTGCTAGGTGAGAGGATCGTAAGCCTGTCTCAGCTACCCTGAGCCTTG
CGACTTAGGCCAGCTCCCTAAGTCTGTTTCCCTCTCCCACACCACCAAAACCTGACCTGTATGA
GTTGTACTTTTGGTTTTATGTCCCGGCATCTGGCATATGGATGAAGAAATGGGGACTACATTAC
CGTCCCCATCTAAGGGGATGTAGCTGCCTCGTACCCGCTCGGGGACGGCTGGCTTGACTGAAAG
GACCCTGCTGTCATGATGGCCCCATTGCTGCTGAAGTCTAGAAACTCCACAGCTGGCTTCTCCT
TGGCCCCACACTTCTTGCTTTTTGCAGGTCAAGGAGTCGGGCATGGGGAGGGGGTGCGGGTTAG
CCTGAGGATACAAAAGGCTCCTTGGGCCTTTCCTCAGCCTCGTGTATGGACATTTTGGTTCAGG
CCAGGCTCAGCTGCAGAAATGGAAATACGGAAATATGTGTACAAGTCACTCATAGGGAGGAGGG
GAGGAGGCTGGACCACTCATAGGGAGGAGGTTGGACCACATGCCTGCAAGTGGTTACAGGGTCT
TACTGTAGCTCATATCAGCATGAAATTGTGGAAATCTCTTGCCTCTGCTTCTGAGTGCAGGGAC
TACATATGGGTGTATGTCGTCGTGCCTGGCTGTAAGACACCCTGTAGGAAAACCCCTCTCCCGG
TGCCTGGCCCTCTACAGTGTTCACAAGGCTTTGCCTCTTCTTAAGTCGGGAGGCAGGAGAAGCT
GGAGGCAGAAGAGCTGGGCCTGGCTAGGCTAGGGGGTCTCTGGTATTTATCAGACATGGGGATT
GATCTCTCTCGAGCCCTCGCCTTGACCCCCAACTAGGACAGTATGGCCTCCGGGTCTCATCCAG
GAAGGGGAGCAGTCCCAAATCATCCTCCTCCATCCCTTTTGTCTGAGTCAGCTTCATGGCTTCC
CAGGGAAGCAAGCAGGTGTGGGCTCTAACAGGAAGGCTTGAAGCTGCTACCTCATGGCAGGGAC
TGCCTTCCCCACAGGTTCCTTGGGCTCCGGTGGTAGGTTCCCAGCCCATCTTCCAGCCCTTCCC
AACAACTACCCCCAACTCCAAACCCCAGTTAGACAATTGGGCAAAGAGCATCAGCCCATATACC
ACTTTGTCCCCAGGATACAGTAGATGCTCTCTGGAGGCTCTGGCAGAGGTGGAGACCGTCATGT
CACTAGCAAGCACAGTAGGACTTAACAGGGTGGTGTGTGAATTAGAGCTGGCTTCATTGTTTGG
AAAGATGTCATGGTACCTGTCCAGTATTAACGTTTGAATGAGGTGTGAGAATATAAGTATCTCT
TGCACACTCCTGTGCGTGCACAAGCCAGAGTATGCAAAGGCTGACTGGGTAGGAGGGGCTGTTA
GTGAACGGCTGAAGAAAGACATCACTTGCCGGACAGCCAGAGGGATACATCTACATGGGGATAA
TACTTAACCCAGAGAGCATTTGTCCAGCCCATTTTCCAAATTGGAAAGTTTCACAAAAGAGGCA
GAGATAAGGACAGGAGAGTGTATCTACCCAGAGACATTCTAAATGACACAAAGTAACAAGTAGG
ACTTTGGGTGCAGCTCAGGGTAGAACTTGCCTAGTATGCATGAGGTCTTAGCTTCAATCTCCAG
GACGGCAAAAAATGGTGTGGTGGTGCATCCCAGCACTCAGGAGGTAGAGGCAAGAAGATGAGCT
CAAAGCTATCCTGAGCTATATTGTGAGGGTAGCCTAGGCTACATGAGTTTCTGTCTTAAAAACA
ACAAAATCCTAGAAAATAGTAAGTTGAAATAAGACTGAAAAACATCAATGTAGATAGATTCCAG
AGTTCTGTGGGTTTATATGAGATGTTTATATTCTACGTTTTATGGTTTATAAAAATAATTATTG
AAAACCAAGTTTGGTCAGGGCTGGGGATGTCTTGTTGGTTAAGAACATCTCGTTCTTGGATCTC
GTTCCCAGCACACACATCAGGCAGCTCACACAGCTGCTGGCAACTCCAGCTCTAGGTGATCTGA
GAACTGTCCTCCCCAATAAGAAAGAAATAAAAAAGAAAAGAAAACCAAGCTTGGTGGCATTGGT
GGCACAGGCCTCTGATTTCAGCATTGGGAAGGCAGAGGCAGGAAGAACACACTGAAGGATAGCC
TGGGCTACGAAGCAAGTAAAAGGCCAGCCTGGGAAACTTAGCAGACCCTTTCTCAAAGTTTACT
GAGTACAGTAAGGAGACACAAAACTTTATATAGAGCAAGAAAAAAAAAATAGCACACCTGGGCA
ACTATCTGTGCACCTCAGGCTGACCTTGAAGTCTAAGGTAGCCGAGGATGATCCTGCCTCCACC
TCCCAGGTGCTGGGATTCCAGGCTTGCACCATCATACCCCGCTCTGCAGTCTATCTTGGTGTAT
CTTGATTATTGAGAACTCTACCCTGGCACCCCACAGCGCCAGGGTAGAGCAGGCTCGGACAATT
GAGAGTTTGCTCTCTAGTGACTTAAGCATGTTACGTTGCACGTATGCCCAGGTCCCAAAGAGAG
GCAGCCCATACTGTAAAGCTTGTCCCGCAGTCAAATGAGGTGTCTTCCTAACTCACAAGTAGCC
CTACACAGATATCCCACCCATTGGGAGCTAAACAACGTGGCTGGTGTAGTGGCACAGGCCCTTA
ATCCCAGCACCCAGAGGCAGGCTGATCTCTATGAGTTCAAGGCCAGCCTGGTCTACATGGTGAG
TTCCAGACCAGCAGGGCTATGTAGTGAAACCCTGTCTTGAAAACAAACAGACAAGACATAAACA
ACTGTACGGTGGCATTGAGTGCCAGCCTGTGTAGATCCCCGGTGGGAGCCTCAGCCTGTGTAGA
TTCCCGGTGGGAGCCTCAGCCTGTGTAGGTCCCTGGTGGGAGCCTCAGCCTGTGTAGATCCCCG
GTGGGAGCCTCAGCCTGTGTAGATCCCCGGTGGGAGCCTCAGCCTGTGTAGATTCCCGGTGGGA
GCCTCAGCCTGTGTAGGTCCCTGGTGGGAGCCTCAGCCTGTGTAGATCCCCGGTGGGAGCCTCA
GCCTGTGTAGATCCCCGGTGGGAGCCTCAGCCTGTGTAGATCCCCGGTGGGAGCCTCAGCCTGT
GTAGATCCCCGGTGGGAGCCTCAGCCTGTGTAGATTCCCGGTGGGAGCCTCAGCCTGTGTAGGT
CCCCGGTGGGAGCCTCAGCCTGTGTAGATTCCCGGTGGGAGCCTCAGCCTGTGTAGGTCCCCGG
TGGGAGCCTCAGCCTGTGTAGATCCCCGGTGGGAGCCTCAGCCTGTGTAGATCCCCGGTGGGAG
CCTGTCGAGTGTTTCCTGCAGTTCTCGGCTGTCTTGCCTGCTGCTGCTGTTCCATTGTGTGTCT
AATAAACTATCTCTTGCCCTTT

hide sequence

RefSeq Acc Id:

XM_017593523 ⟹ XP_017449012

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,821,084 - 156,835,558 (-)	NCBI
mRatBN7.2	5	151,537,870 - 151,549,739 (-)	NCBI
Rnor_6.0	5	157,744,945 - 157,757,235 (-)	NCBI

Sequence:

show sequence

ACAGAGTTTAAAAAGAAAAAAAAAAAAGCCGGGGATATAGAACAGTTGCTAACCTCCTAGGCAA
TACACAAAAAGTTCTAGATCTGACCTCCAAAACAAACAAACAAAATATTCCTAAATATTTGCAC
GTTGCATCAAAAGGTGCTGTTGGCCCAACCACTTTATGTGAGAGCTCATTTACCTTGCACAGCA
GCTGTGTGACGTAGGGCCTGTTGTTATCCCCACTGTGCAGAGGACAGGACAGTAACTGACAGTC
ACAGGATCGTGAATGGGGCTAGACCTAAGGCTGAAGACCTTTTTATAGAACAAACCTTTGCCAG
CCTCTGACCCCTTGCCCATGTTCATAAACCTGCACTTTCTTCCCCGCTGGGACCCTCCCTCTGC
AGCCATGGTCTGGAGGACACTGGTCGCCAGCAACTTTTCCACCTGCCCCAATGGCTCTATCCAG
TGGATCTGGGATGTGTTTGGTGAATGTGCCCAGGATGGCTGGGATGAGGCCAGCGTGGCCCTGG
GCTTGGTCTCCATTTTCTGCTTTGCTGCGTCTACCTTTCCGTGACCAGTACATCAAAGCCTGCA
AGACAGGCAACATGGACCAGGCCCTGTCACTGTGGTTCCTGCTGGGCTGGATCGGTGGAGACTC
CTGCAACCTCATTGGTTCCTTTCTGGCAGACCAGCTACCCCTGCAGACCTACACGGCTGTGTAT
TATGTCCTGGCCGACCTTTTGATGCTGACACTGTACTTCCACTACAAGTTCAAGAAGCAGCCCT
CTCTGTTGTCTGCCCCAATCAATTCTGTGCTCTTGTTCATCTTGGGGACGGTGTGCATCACACC
ACTGTTGAGCAGCACTGATCCTGTGGCTGTCCCCAGGGAAGGCTTCAGGGGGCGGACGCTCCTG
TCTGTGGAGCCAGGCAATAAGCCCTTCACAAAGAAGGAGGTCGTCGGTTTTGTCATTGGCTCCG
CCTCCAGCGTGCTGTACCTGCTCTCAAGGCTGCCGCAGATTCGCACCAATTTCGTACGGCAGTC
AACCCAAGGCATTTCCTACTCGCTGTTTGCACTGGTGATGCTGGGGAACACGCTATATGGGCTC
AGTGTGCTGCTCAAAAACCCCGAGGTGGGCCAGAGTGAGGGCAGCTATCTGCTGCACCACCTGC
CCTGGCTCGTGGGCAGCCTGGGAGTGCTCCTGCTTGACACCATTATCTCCATCCAGTTCCTGGT
GTACAGAAGCCATGATGCTGATGCTGCCTCAGAGCGAGAGCCGCTCCTCCCAAGCTGACCCCAC
AGCTGCCCTCCCAGGAAGGAGTGATACTGCCGCCACTGGACTGGGCCTAGGAGGTGGCCTGGGA
CTCTGGGCCTGGCTGCCTCCCCTCCACACCTGGCCTTCAGACAGGTCTAGAGTTGGCACAGGTC
TGGAGTTGGCGTGTGCTATGCCGGGACATACCTCTCAGGTATATGACAGCTGTCCGAGGAGCCT
CTAGGGCACCCCAGAAGACGGTGTGGCCTCCTCCCAATCAAACTACCTCAATCTGACTATGTAC
TCCTGGCTACATCATAGCTGGGGGACCCAGGGTTGTCCCTCTGACTGGGCACAACCTAGTAAAT
AGTACCTTCCAGCTGGGCCTGTTTCTGCTGCTCCTTCCCATGGTGCTTGAGGTCTAGGCAGGGA
TCCAGGGCAAGCCCATCCTGATAGGGGGGGCACGTGCAGCCTCCCTGGCCCTTGGCATCCTAAC
TTGTATCCTTCTGTCCTCTTGTACACAGACCCTACCTGGTGTGGGACACCAGTGGTCTCTCTGT
TCCTGGGGCTCTGGGAGAAGCAGATAACCAAGGGCAGGCTTTGGTTGAGCATCACCAGAGGCCT
GGCATGACCATGTGACCGCCCCCTCTGTCCTTGCCCAGGCCGTGTAGGGTGAGGCAGCTAGCCC
AAAGCGAGGCATGTAGTCAAGTGTCTCATACAGTCAGAGCTCAGTGATGGTCGCTGAAGTGGAG
AAGAGGGGAAGACTGGTGCCTTTCTGAGGAAGGCAGAGACTAGAAGCACAGGTGGAAAACAAGG
CCAGCAGGAGACGGGTGACGGGGGCAGAGAGGAAGGGAGGAAGATTGGTCTCAGCGGTCTTTGT
TACAACACCTTTAGGGGACAGAGGACCAGCCTCCTCTCCTGCTAGCCTCAGCTTACTGATACAT
TATTGTAGGTCCAGAAAGTCAGATGCAGGGCCAGGGGGCTGCCTGCCAGAGACAAACAGGGCAG
CCGCCTCAGTGCTTTTTGTAGCTTCTCTGTCCATAGCTGAGGAGAAGATCCTGGCACAGACCCA
GGCAAGGCATATGGTGCTCCCGGTCCCTGCTCTTAACCCACTGCTGGCTTCAGGTGATCTTTGC
AGCTCATGCCGTCCTGGGACTTGGCTCTAGGCTAGTTTCCTAGGGCCAGATGGCACCTTTCCAA
ATCCTGAAGATCTGGGGCCTCAGTGTGGTACAGGACCCCAGGTGCACGGGCAGGACAACATGAA
ATGCCAGCCCTGTCTGAGCTCTCCTGGGTCTGTCAGGCGGAGCGACAACCCTTCATGGGGGAGT
CGTGCTTTGCCCACAGGAATTCCTGTCTGACAGAGGAGGTGGTCTCAGGAAGGTTGCAGTTCCT
CTAAACCTCAGTTCCTCCTCTCTTCTGGAGGCTCGCTCCAGTACTCCAAGGAGGGGTCAGAGTA
GGGAGCTTGCAGAACCTGGTGGCCTGGTTATTTTATTTGCTAGGTGAGAGGATCGTAAGCCTGT
CTCAGCTACCCTGAGCCTTGCGACTTAGGCCAGCTCCCTAAGTCTGTTTCCCTCTCCCACACCA
CCAAAACCTGACCTGTATGAGTTGTACTTTTGGTTTTATGTCCCGGCATCTGGCATATGGATGA
AGAAATGGGGACTACATTACCGTCCCCATCTAAGGGGATGTAGCTGCCTCGTACCCGCTCGGGG
ACGGCTGGCTTGACTGAAAGGACCCTGCTGTCATGATGGCCCCATTGCTGCTGAAGTCTAGAAA
CTCCACAGCTGGCTTCTCCTTGGCCCCACACTTCTTGCTTTTTGCAGGTCAAGGAGTCGGGCAT
GGGGAGGGGGTGCGGGTTAGCCTGAGGATACAAAAGGCTCCTTGGGCCTTTCCTCAGCCTCGTG
TATGGACATTTTGGTTCAGGCCAGGCTCAGCTGCAGAAATGGAAATACGGAAATATGTGTACAA
GTCACTCATAGGGAGGAGGGGAGGAGGCTGGACCACTCATAGGGAGGAGGTTGGACCACATGCC
TGCAAGTGGTTACAGGGTCTTACTGTAGCTCATATCAGCATGAAATTGTGGAAATCTCTTGCCT
CTGCTTCTGAGTGCAGGGACTACATATGGGTGTATGTCGTCGTGCCTGGCTGTAAGACACCCTG
TAGGAAAACCCCTCTCCCGGTGCCTGGCCCTCTACAGTGTTCACAAGGCTTTGCCTCTTCTTAA
GTCGGGAGGCAGGAGAAGCTGGAGGCAGAAGAGCTGGGCCTGGCTAGGCTAGGGGGTCTCTGGT
ATTTATCAGACATGGGGATTGATCTCTCTCGAGCCCTCGCCTTGACCCCCAACTAGGACAGTAT
GGCCTCCGGGTCTCATCCAGGAAGGGGAGCAGTCCCAAATCATCCTCCTCCATCCCTTTTGTCT
GAGTCAGCTTCATGGCTTCCCAGGGAAGCAAGCAGGTGTGGGCTCTAACAGGAAGGCTTGAAGC
TGCTACCTCATGGCAGGGACTGCCTTCCCCACAGGTTCCTTGGGCTCCGGTGGTAGGTTCCCAG
CCCATCTTCCAGCCCTTCCCAACAACTACCCCCAACTCCAAACCCCAGTTAGACAATTGGGCAA
AGAGCATCAGCCCATATACCACTTTGTCCCCAGGATACAGTAGATGCTCTCTGGAGGCTCTGGC
AGAGGTGGAGACCGTCATGTCACTAGCAAGCACAGTAGGACTTAACAGGGTGGTGTGTGAATTA
GAGCTGGCTTCATTGTTTGGAAAGATGTCATGGTACCTGTCCAGTATTAACGTTTGAATGAGGT
GTGAGAATATAAGTATCTCTTGCACACTCCTGTGCGTGCACAAGCCAGAGTATGCAAAGGCTGA
CTGGGTAGGAGGGGCTGTTAGTGAACGGCTGAAGAAAGACATCACTTGCCGGACAGCCAGAGGG
ATACATCTACATGGGGATAATACTTAACCCAGAGAGCATTTGTCCAGCCCATTTTCCAAATTGG
AAAGTTTCACAAAAGAGGCAGAGATAAGGACAGGAGAGTGTATCTACCCAGAGACATTCTAAAT
GACACAAAGTAACAAGTAGGACTTTGGGTGCAGCTCAGGGTAGAACTTGCCTAGTATGCATGAG
GTCTTAGCTTCAATCTCCAGGACGGCAAAAAATGGTGTGGTGGTGCATCCCAGCACTCAGGAGG
TAGAGGCAAGAAGATGAGCTCAAAGCTATCCTGAGCTATATTGTGAGGGTAGCCTAGGCTACAT
GAGTTTCTGTCTTAAAAACAACAAAATCCTAGAAAATAGTAAGTTGAAATAAGACTGAAAAACA
TCAATGTAGATAGATTCCAGAGTTCTGTGGGTTTATATGAGATGTTTATATTCTACGTTTTATG
GTTTATAAAAATAATTATTGAAAACCAAGTTTGGTCAGGGCTGGGGATGTCTTGTTGGTTAAGA
ACATCTCGTTCTTGGATCTCGTTCCCAGCACACACATCAGGCAGCTCACACAGCTGCTGGCAAC
TCCAGCTCTAGGTGATCTGAGAACTGTCCTCCCCAATAAGAAAGAAATAAAAAAGAAAAGAAAA
CCAAGCTTGGTGGCATTGGTGGCACAGGCCTCTGATTTCAGCATTGGGAAGGCAGAGGCAGGAA
GAACACACTGAAGGATAGCCTGGGCTACGAAGCAAGTAAAAGGCCAGCCTGGGAAACTTAGCAG
ACCCTTTCTCAAAGTTTACTGAGTACAGTAAGGAGACACAAAACTTTATATAGAGCAAGAAAAA
AAAAATAGCACACCTGGGCAACTATCTGTGCACCTCAGGCTGACCTTGAAGTCTAAGGTAGCCG
AGGATGATCCTGCCTCCACCTCCCAGGTGCTGGGATTCCAGGCTTGCACCATCATACCCCGCTC
TGCAGTCTATCTTGGTGTATCTTGATTATTGAGAACTCTACCCTGGCACCCCACAGCGCCAGGG
TAGAGCAGGCTCGGACAATTGAGAGTTTGCTCTCTAGTGACTTAAGCATGTTACGTTGCACGTA
TGCCCAGGTCCCAAAGAGAGGCAGCCCATACTGTAAAGCTTGTCCCGCAGTCAAATGAGGTGTC
TTCCTAACTCACAAGTAGCCCTACACAGATATCCCACCCATTGGGAGCTAAACAACGTGGCTGG
TGTAGTGGCACAGGCCCTTAATCCCAGCACCCAGAGGCAGGCTGATCTCTATGAGTTCAAGGCC
AGCCTGGTCTACATGGTGAGTTCCAGACCAGCAGGGCTATGTAGTGAAACCCTGTCTTGAAAAC
AAACAGACAAGACATAAACAACTGTACGGTGGCATTGAGTGCCAGCCTGTGTAGATCCCCGGTG
GGAGCCTCAGCCTGTGTAGATTCCCGGTGGGAGCCTCAGCCTGTGTAGGTCCCTGGTGGGAGCC
TCAGCCTGTGTAGATCCCCGGTGGGAGCCTCAGCCTGTGTAGATCCCCGGTGGGAGCCTCAGCC
TGTGTAGATTCCCGGTGGGAGCCTCAGCCTGTGTAGGTCCCTGGTGGGAGCCTCAGCCTGTGTA
GATCCCCGGTGGGAGCCTCAGCCTGTGTAGATCCCCGGTGGGAGCCTCAGCCTGTGTAGATCCC
CGGTGGGAGCCTCAGCCTGTGTAGATCCCCGGTGGGAGCCTCAGCCTGTGTAGATTCCCGGTGG
GAGCCTCAGCCTGTGTAGGTCCCCGGTGGGAGCCTCAGCCTGTGTAGATTCCCGGTGGGAGCCT
CAGCCTGTGTAGGTCCCCGGTGGGAGCCTCAGCCTGTGTAGATCCCCGGTGGGAGCCTCAGCCT
GTGTAGATCCCCGGTGGGAGCCTGTCGAGTGTTTCCTGCAGTTCTCGGCTGTCTTGCCTGCTGC
TGCTGTTCCATTGTGTGTCTAATAAACTATCTCTTGCCCTTT

hide sequence

RefSeq Acc Id:

XM_063288076 ⟹ XP_063144146

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,821,084 - 156,835,452 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001386161	(Get FASTA)	NCBI Sequence Viewer
	NP_001386162	(Get FASTA)	NCBI Sequence Viewer
	NP_001386163	(Get FASTA)	NCBI Sequence Viewer
	XP_006239301	(Get FASTA)	NCBI Sequence Viewer
	XP_017449012	(Get FASTA)	NCBI Sequence Viewer
	XP_063144146	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI58608	(Get FASTA)	NCBI Sequence Viewer
	B0BMY1	(Get FASTA)	NCBI Sequence Viewer
	EDL80912	(Get FASTA)	NCBI Sequence Viewer
	EDL80913	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000023896
	ENSRNOP00000107028

RefSeq Acc Id:	XP_006239301 ⟸ XM_006239239
- Peptide Label:	isoform X1
- UniProtKB:	F7FC79 (UniProtKB/Swiss-Prot), B0BMY1 (UniProtKB/Swiss-Prot), A0A8I5Y800 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVWRTLVASNFSTCPNGSIQWIWDVFGECAQDGWDEASVALGLVSIFCFAASTFPQYIKACKTG NMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLLMLTLYFHYKFKKQPSLL SAPINSVLLFILGTVCITPLLSSTDPVAVPREGFRGRTLLSVEPGNKPFTKKEVVGFVIGSASS VLYLLSRLPQIRTNFVRQSTQGISYSLFALVMLGNTLYGLSVLLKNPEVGQSEGSYLLHHLPWL VGSLGVLLLDTIISIQFLVYRSHDADAASEREPLLPS hide sequence

RefSeq Acc Id:

XP_017449012 ⟸ XM_017593523

- Peptide Label:

isoform X2

- Sequence:

show sequence

MALSSGSGMCLVNVPRMAGMRPAWPWAWSPFSALLRLPFRDQYIKACKTGNMDQALSLWFLLGW
IGGDSCNLIGSFLADQLPLQTYTAVYYVLADLLMLTLYFHYKFKKQPSLLSAPINSVLLFILGT
VCITPLLSSTDPVAVPREGFRGRTLLSVEPGNKPFTKKEVVGFVIGSASSVLYLLSRLPQIRTN
FVRQSTQGISYSLFALVMLGNTLYGLSVLLKNPEVGQSEGSYLLHHLPWLVGSLGVLLLDTIIS
IQFLVYRSHDADAASEREPLLPS

hide sequence

Ensembl Acc Id:

ENSRNOP00000023896 ⟸ ENSRNOT00000023896

Ensembl Acc Id:

ENSRNOP00000072028 ⟸ ENSRNOT00000083341

Ensembl Acc Id:

ENSRNOP00000077592 ⟸ ENSRNOT00000099105

RefSeq Acc Id:	NP_001386162 ⟸ NM_001399233
- Peptide Label:	isoform 2
- UniProtKB:	B0BMY1 (UniProtKB/Swiss-Prot), F7FC79 (UniProtKB/Swiss-Prot), A0A8I5Y800 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386161 ⟸ NM_001399232
- Peptide Label:	isoform 1
- UniProtKB:	A0A8L2QDE2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386163 ⟸ NM_001399234
- Peptide Label:	isoform 3

RefSeq Acc Id:	XP_063144146 ⟸ XM_063288076
- Peptide Label:	isoform X2

Protein Domains

PQ-loop

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B0BMY1-F1-model_v2	AlphaFold	B0BMY1	1-293	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694204

Promoter ID:

EPDNEW_R4727

Type:

initiation region

Name:

Pqlc2_1

Description:

PQ loop repeat containing 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	157,759,316 - 157,759,376	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311627	AgrOrtholog
BioCyc Gene	G2FUF-39421	BioCyc
Ensembl Genes	ENSRNOG00000017706	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000023896	ENTREZGENE
	ENSRNOT00000099105	ENTREZGENE
	ENSRNOT00000157253	ENTREZGENE
Gene3D-CATH	1.20.1280.290	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7192223	IMAGE-MGC_LOAD
InterPro	LAAT-1	UniProtKB/Swiss-Prot
	PQ-loop_rpt	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:187473	IMAGE-MGC_LOAD
NCBI Gene	362642	ENTREZGENE
PANTHER	LYSOSOMAL AMINO ACID TRANSPORTER 1 HOMOLOG	UniProtKB/Swiss-Prot
	SEVEN TRANSMEMBRANE PROTEIN 1-RELATED	UniProtKB/Swiss-Prot
Pfam	PQ-loop	UniProtKB/Swiss-Prot
PhenoGen	Slc66a1	PhenoGen
RatGTEx	ENSRNOG00000017706	RatGTEx
SMART	CTNS	UniProtKB/Swiss-Prot
UniProt	A0A8I5Y800	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2QDE2	ENTREZGENE, UniProtKB/TrEMBL
	B0BMY1	ENTREZGENE
	F7FC79	ENTREZGENE
	LAAT1_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	F7FC79	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-08-09	Slc66a1	solute carrier family 66 member 1	Pqlc2	PQ loop repeat containing 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Pqlc2	PQ loop repeat containing 2	Pqlc2_predicted	PQ loop repeat containing 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Pqlc2_predicted	PQ loop repeat containing 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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