Gene: Plod1 (procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1) Rattus norvegicus
Symbol: Plod1
Name: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
Description: ENCODES a protein that exhibits ferrous iron binding; L-ascorbic acid binding; peptide binding; INVOLVED IN cellular response to hormone stimulus; peptidyl-lysine hydroxylation; response to hypoxia; PARTICIPATES IN lysine degradation pathway; ASSOCIATED WITH Hypothyroidism; Aortic Aneurysm, Thoracic (ortholog); Charcot-Marie-Tooth Disease (ortholog); FOUND IN catalytic complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LH1; lysyl hydroxylase 1; Plod; procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1; procollagen-lysine 2-oxoglutarate 5-dioxygenase (lysine hydroxylase Ehlers-Danlos syndrome type VI); procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI); procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Homo sapiens (human) : PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1)  HGNC  AGR
Mus musculus (house mouse) : Plod1 (procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Plod1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1)
Canis lupus familiaris (dog) : PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plod1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1)
more info ...
Allele / Splice: Plod1em1Mcwi  
Genetic Models: SS-Plod1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05164,720,629 - 164,747,071 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05168,379,092 - 168,405,534 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45164,987,252 - 165,012,581 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15164,997,439 - 165,022,772 (-)NCBI
Celera5156,623,980 - 156,649,807 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Plod1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621382
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE