Padi4 (peptidyl arginine deiminase 4) - Rat Genome Database

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Gene: Padi4 (peptidyl arginine deiminase 4) Rattus norvegicus
Analyze
Symbol: Padi4
Name: peptidyl arginine deiminase 4
RGD ID: 3290
Description: Enables protein-arginine deiminase activity. Predicted to be involved in nucleosome assembly; post-translational protein modification; and stem cell population maintenance. Predicted to be located in nucleus. Predicted to be part of protein-containing complex. Orthologous to human PADI4 (peptidyl arginine deiminase 4); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5-triiodo-L-thyronine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: PAD-R4; Pdi4; peptidyl arginine deiminase type IV; peptidyl arginine deiminase, type 4; peptidyl arginine deiminase, type IV; peptidylarginine deiminase IV; peptidylarginine deiminase type alpha; protein-arginine deiminase type IV; protein-arginine deiminase type-4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25153,041,351 - 153,074,412 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,041,352 - 153,074,362 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,737,777 - 155,763,407 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05157,512,294 - 157,538,146 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05157,493,425 - 157,526,421 (-)NCBIRnor_WKY
Rnor_6.05159,260,675 - 159,293,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,260,675 - 159,293,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05162,967,383 - 163,001,294 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,580,718 - 159,614,628 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,590,905 - 159,624,816 (-)NCBI
Celera5151,402,208 - 151,435,173 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
nucleus  (ISO,ISS)
protein-containing complex  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin. Ishigami A, etal., Arch Biochem Biophys. 2002 Nov 1;407(1):25-31.
4. Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid-treated culture of a newborn rat keratinocyte cell line. Ishigami A, etal., FEBS Lett 1998 Aug 14;433(1-2):113-8.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
12. Cloning of cDNA encoding a novel isoform (type IV) of peptidylarginine deiminase from rat epidermis. Yamakoshi A, etal., Biochim Biophys Acta 1998 Jul 28;1386(1):227-32.
Additional References at PubMed
PMID:15247907   PMID:15339660   PMID:16567635   PMID:21584310   PMID:24463520  


Genomics

Comparative Map Data
Padi4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25153,041,351 - 153,074,412 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,041,352 - 153,074,362 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,737,777 - 155,763,407 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05157,512,294 - 157,538,146 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05157,493,425 - 157,526,421 (-)NCBIRnor_WKY
Rnor_6.05159,260,675 - 159,293,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,260,675 - 159,293,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05162,967,383 - 163,001,294 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,580,718 - 159,614,628 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,590,905 - 159,624,816 (-)NCBI
Celera5151,402,208 - 151,435,173 (-)NCBICelera
Cytogenetic Map5q36NCBI
PADI4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,308,197 - 17,364,004 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl117,308,195 - 17,364,004 (+)EnsemblGRCh38hg38GRCh38
GRCh37117,634,692 - 17,690,499 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,507,279 - 17,563,082 (+)NCBINCBI36Build 36hg18NCBI36
Build 34117,379,997 - 17,435,801NCBI
Celera115,960,064 - 16,015,550 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,880,966 - 15,936,461 (+)NCBIHuRef
CHM1_1117,743,078 - 17,796,994 (+)NCBICHM1_1
T2T-CHM13v2.0117,122,255 - 17,177,953 (+)NCBIT2T-CHM13v2.0
Padi4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,472,819 - 140,501,514 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,473,176 - 140,501,547 (-)EnsemblGRCm39 Ensembl
GRCm384140,745,508 - 140,774,239 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,745,865 - 140,774,236 (-)EnsemblGRCm38mm10GRCm38
MGSCv374140,301,423 - 140,330,118 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,017,941 - 140,046,261 (-)NCBIMGSCv36mm8
Celera4142,524,735 - 142,585,456 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map472.34NCBI
Padi4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,536,423 - 1,561,130 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,536,917 - 1,560,508 (-)NCBIChiLan1.0ChiLan1.0
PADI4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1117,311,436 - 17,365,670 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,311,436 - 17,365,426 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0116,255,680 - 16,311,256 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PADI4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1280,912,814 - 80,942,767 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl280,905,391 - 80,993,973 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,450,334 - 77,480,310 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,560,676 - 81,590,655 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,560,677 - 81,641,599 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,313,557 - 78,343,545 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,329,140 - 79,359,110 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,398,999 - 80,428,932 (-)NCBIUU_Cfam_GSD_1.0
Padi4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,394,401 - 38,414,845 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364744,221,672 - 4,238,599 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049364744,219,183 - 4,239,551 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PADI4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,935,889 - 75,966,293 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,935,909 - 75,966,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2670,279,760 - 70,310,373 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PADI4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,212,214 - 115,262,634 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,212,254 - 115,262,581 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666033849,828 - 904,511 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Padi4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,871,078 - 2,898,584 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,871,002 - 2,898,748 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Padi4
247 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:221
Count of miRNA genes:156
Interacting mature miRNAs:173
Transcripts:ENSRNOT00000009081
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 1
Low 2 6 29 22 18 22 30 37 11
Below cutoff 32 21 16 1 16 5 5 34 5 3 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000009081   ⟹   ENSRNOP00000009081
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5153,041,352 - 153,074,362 (-)Ensembl
Rnor_6.0 Ensembl5159,260,675 - 159,293,673 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107432   ⟹   ENSRNOP00000090454
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5153,041,352 - 153,074,362 (-)Ensembl
RefSeq Acc Id: NM_017227   ⟹   NP_058923
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25153,041,352 - 153,074,362 (-)NCBI
Rnor_6.05159,260,675 - 159,293,673 (-)NCBI
Rnor_5.05162,967,383 - 163,001,294 (-)NCBI
RGSC_v3.45159,580,718 - 159,614,628 (-)RGD
Celera5151,402,208 - 151,435,173 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239145   ⟹   XP_006239207
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25153,041,351 - 153,074,412 (-)NCBI
Rnor_6.05159,260,679 - 159,293,906 (-)NCBI
Rnor_5.05162,967,383 - 163,001,294 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593205   ⟹   XP_017448694
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25153,041,351 - 153,071,695 (-)NCBI
Rnor_6.05159,260,679 - 159,290,996 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593206   ⟹   XP_017448695
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25153,041,351 - 153,071,695 (-)NCBI
Rnor_6.05159,260,679 - 159,290,996 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109374   ⟹   XP_038965302
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25153,041,351 - 153,071,426 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_058923   ⟸   NM_017227
- UniProtKB: O35117 (UniProtKB/Swiss-Prot),   O88807 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006239207   ⟸   XM_006239145
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017448695   ⟸   XM_017593206
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017448694   ⟸   XM_017593205
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000009081   ⟸   ENSRNOT00000009081
RefSeq Acc Id: XP_038965302   ⟸   XM_039109374
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000090454   ⟸   ENSRNOT00000107432
Protein Domains
Protein-arginine deiminase (PAD) central   Protein-arginine deiminase (PAD) N-terminal   Protein-arginine deiminase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88807-F1-model_v2 AlphaFold O88807 1-666 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3290 AgrOrtholog
BioCyc Gene G2FUF-39386 BioCyc
BioCyc Pathway PWY-4921 [protein citrullination] BioCyc
Ensembl Genes ENSRNOG00000006855 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000009081 ENTREZGENE
  ENSRNOP00000009081.1 UniProtKB/Swiss-Prot
  ENSRNOP00000090454.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009081 ENTREZGENE
  ENSRNOT00000009081.3 UniProtKB/Swiss-Prot
  ENSRNOT00000107432.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1700 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1860 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cupredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAD_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAD_central_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAD_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAD_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_Arg_deaminase_cen_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29512 UniProtKB/Swiss-Prot
NCBI Gene 29512 ENTREZGENE
PANTHER PROTEIN-ARGININE DEIMINASE TYPE-4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10837 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAD_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAD_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Padi4 PhenoGen
PIRSF Protein-arginine_deiminase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Pentein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF110083 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49503 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC232078
UniProt A0A8I6ADU5_RAT UniProtKB/TrEMBL
  O35117 ENTREZGENE
  O88807 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O35117 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-14 Padi4  peptidyl arginine deiminase 4  Padi4  peptidyl arginine deiminase, type IV  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Padi4  peptidyl arginine deiminase, type IV  Pdi4  peptidyl arginine deiminase, type 4  Symbol and Name updated 1299863 APPROVED
2002-06-10 Pdi4  peptidyl arginine deiminase, type 4      Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein 666 amino acids; 74.5 kDa 69924