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Gene: Aldh4a1 (aldehyde dehydrogenase 4 family, member A1) Rattus norvegicus

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Symbol:

Aldh4a1

Name:

aldehyde dehydrogenase 4 family, member A1

RGD ID:

1624206

Description:

Predicted to enable L-glutamate gamma-semialdehyde dehydrogenase activity; aldehyde dehydrogenase (NAD+) activity; and identical protein binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway; L-proline catabolic process to L-glutamate; and detection of chemical stimulus. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in hyperprolinemia type 2. Orthologous to human ALDH4A1 (aldehyde dehydrogenase 4 family member A1); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; AGAT deficiency pathway; arginine and proline metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

aldehyde dehydrogenase family 4 member A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; L-glutamate gamma-semialdehyde dehydrogenase; LOC641316; P5C dehydrogenase; similar to aldehyde dehydrogenase 4 family, member A1

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ALDH4A1 (aldehyde dehydrogenase 4 family member A1)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Aldh4a1 (aldehyde dehydrogenase 4 family, member A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Aldh4a1 (aldehyde dehydrogenase 4 family member A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ALDH4A1 (aldehyde dehydrogenase 4 family member A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ALDH4A1 (aldehyde dehydrogenase 4 family member A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Aldh4a1 (aldehyde dehydrogenase 4 family member A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ALDH4A1 (aldehyde dehydrogenase 4 family member A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ALDH4A1 (aldehyde dehydrogenase 4 family member A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Aldh4a1 (aldehyde dehydrogenase 4 family member A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ALDH4A1 (aldehyde dehydrogenase 4 family member A1)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Aldh4a1 (aldehyde dehydrogenase 4 family, member A1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	aldh4a1 (aldehyde dehydrogenase 4 family, member A1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	P5CDh1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PUT2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PUT2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	alh-6	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG6661	Alliance	DIOPT (OrthoFinder\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	aldh4a1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	aldh4a1	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	157,163,189 - 157,188,673 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	157,162,945 - 157,188,673 (+)	Ensembl				GRCr8
mRatBN7.2	5	151,880,002 - 151,905,491 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	151,830,701 - 151,925,345 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	154,578,425 - 154,603,973 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	156,352,798 - 156,378,348 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	156,333,760 - 156,359,284 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	158,090,238 - 158,115,725 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	158,042,587 - 158,135,733 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	161,829,323 - 161,854,796 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	158,437,691 - 158,453,827 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	150,256,652 - 150,282,086 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-hydroxy-3-methylglutaryl-CoA lyase deficiency (ISO)

autism spectrum disorder (ISO)

chromosome 1p36 deletion syndrome (ISO)

congenital disorder of glycosylation Ir (ISO)

COVID-19 (ISO)

hyperprolinemia (ISO)

hyperprolinemia type 2 (ISO)

intellectual disability (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

Parkinson's disease 6 (ISO)

pre-malignant neoplasm (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-dexrazoxane (ISO)

(+)-schisandrin B (EXP)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrabromodibenzodioxine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

8'-apo-beta,psi-caroten-8'-al (ISO)

acetamide (EXP)

acrylamide (EXP,ISO)

actinomycin D (ISO)

aflatoxin B1 (EXP,ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (EXP,ISO)

beta-carotene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

butylated hydroxyanisole (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

clofibric acid (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

ethanol (ISO)

fenamidone (ISO)

folic acid (ISO)

furan (EXP)

glafenine (EXP)

glyphosate (ISO)

hesperetin (ISO)

indometacin (EXP,ISO)

inulin (ISO)

ivermectin (ISO)

L-methionine (ISO)

manganese(II) chloride (EXP)

methapyrilene (EXP)

nitrofen (EXP)

Nutlin-3 (ISO)

O-methyleugenol (ISO)

ochratoxin A (EXP)

okadaic acid (ISO)

paracetamol (ISO)

paraquat (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phlorizin (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

propanal (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (EXP)

SB 431542 (ISO)

selenium atom (ISO)

sodium arsenite (EXP,ISO)

spironolactone (ISO)

sulforaphane (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (EXP,ISO)

tetrachloromethane (EXP,ISO)

triadimefon (EXP)

triclosan (ISO)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus (IEA)

G protein-coupled receptor signaling pathway (IEA)

L-proline catabolic process to L-glutamate (IEA)

proline metabolic process (IEA)

signal transduction (IEA)

Cellular Component

cytosol (IEA,ISO)

intermediate filament (IEA)

membrane (IEA)

mitochondrial matrix (IEA)

mitochondrion (IEA,ISO)

plasma membrane (IEA)

Molecular Function

aldehyde dehydrogenase (NAD+) activity (IEA,ISO)

G protein-coupled receptor activity (IEA)

identical protein binding (IEA,ISO)

L-glutamate gamma-semialdehyde dehydrogenase activity (IBA,IEA,ISO)

oxidoreductase activity (IEA)

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

2-hydroxyglutaric aciduria pathway (ISO)

AGAT deficiency pathway (ISO)

alanine, aspartate and glutamate metabolic pathway (IEA)

arginine and proline metabolic pathway (IEA,ISO)

glutamic acid/glutamate metabolic pathway (ISO)

guanidinoacetate methyltransferase deficiency pathway (ISO)

gyrate atrophy pathway (ISO)

homocarnosinosis pathway (ISO)

hyperprolinemia type I pathway (ISO)

hyperprolinemia type II pathway (ISO)

ornithine translocase deficiency pathway (ISO)

prolidase deficiency pathway (ISO)

succinic semialdehyde dehydrogenase deficiency pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:4015840	PMID:8621661	PMID:12477932	PMID:14651853	PMID:15057822	PMID:18614015	PMID:22516612	PMID:23928095

Genomics

Comparative Map Data

Aldh4a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	157,163,189 - 157,188,673 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	157,162,945 - 157,188,673 (+)	Ensembl				GRCr8
mRatBN7.2	5	151,880,002 - 151,905,491 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	151,830,701 - 151,925,345 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	154,578,425 - 154,603,973 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	156,352,798 - 156,378,348 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	156,333,760 - 156,359,284 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	158,090,238 - 158,115,725 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	158,042,587 - 158,135,733 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	161,829,323 - 161,854,796 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	158,437,691 - 158,453,827 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	150,256,652 - 150,282,086 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

ALDH4A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	18,871,430 - 18,902,555 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	18,871,430 - 18,902,724 (-)	Ensembl			hg38	GRCh38
GRCh37	1	19,197,924 - 19,229,049 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	19,070,513 - 19,101,659 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	18,943,231 - 18,974,378	NCBI
Celera	1	17,525,220 - 17,556,609 (-)	NCBI		Celera
Cytogenetic Map	1	p36.13	NCBI
HuRef	1	17,442,100 - 17,473,468 (-)	NCBI		HuRef
CHM1_1	1	19,307,273 - 19,338,658 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	18,691,214 - 18,722,363 (-)	NCBI		T2T-CHM13v2.0

Aldh4a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	139,348,404 - 139,377,002 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	139,350,177 - 139,377,001 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	139,622,871 - 139,649,691 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	139,622,866 - 139,649,690 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	139,178,809 - 139,205,606 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	138,895,086 - 138,921,763 (+)	NCBI		MGSCv36	mm8
Celera	4	141,417,063 - 141,444,074 (+)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	70.79	NCBI

Aldh4a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955527	338,593 - 372,872 (+)	Ensembl
ChiLan1.0	NW_004955527	338,593 - 369,528 (+)	NCBI	ChiLan1.0	ChiLan1.0

ALDH4A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	208,212,985 - 208,244,303 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	207,329,575 - 207,360,881 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	17,829,723 - 17,861,008 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	18,878,421 - 18,909,615 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	18,878,421 - 18,909,615 (-)	Ensembl			panPan2	panpan1.1

ALDH4A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	79,688,078 - 79,712,340 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	79,688,086 - 79,710,540 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	76,202,258 - 76,226,797 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	80,311,305 - 80,335,987 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	80,311,248 - 80,335,984 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	77,070,827 - 77,093,559 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	78,080,932 - 78,105,430 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	79,151,584 - 79,176,100 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Aldh4a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	39,392,819 - 39,421,970 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	5,218,686 - 5,246,664 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	5,217,601 - 5,246,718 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALDH4A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	77,374,002 - 77,404,036 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	77,373,999 - 77,404,015 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	71,494,105 - 71,512,632 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ALDH4A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	113,661,850 - 113,693,665 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666033	2,463,684 - 2,495,495 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aldh4a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	4,051,178 - 4,082,142 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624764	4,051,999 - 4,081,954 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Aldh4a1
258 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
2302369	Scl60	Serum cholesterol level QTL 60	3.13		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	143608201	161165651	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	144358090	157869054	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	151113452	164465185	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	143799107	158428037	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	151113452	166875058	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	144377876	161317411	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
1298090	Bp155	Blood pressure QTL 155	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	151006154	161165494	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat

Markers in Region

RH133354

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	151,905,182 - 151,905,385 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	158,115,417 - 158,115,619	NCBI	Rnor6.0
Rnor_5.0	5	161,854,488 - 161,854,690	UniSTS	Rnor5.0
RGSC_v3.4	5	158,453,519 - 158,453,721	UniSTS	RGSC3.4
Celera	5	150,281,778 - 150,281,980	UniSTS
RH 3.4 Map	5	1046.2	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001134698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000077863 ⟹ ENSRNOP00000072481

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,909,648 - 151,925,345 (+)	Ensembl
Rnor_6.0 Ensembl	5	158,119,894 - 158,135,733 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079516 ⟹ ENSRNOP00000069536

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,857,371 - 151,905,482 (+)	Ensembl
Rnor_6.0 Ensembl	5	158,090,238 - 158,115,725 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000080108 ⟹ ENSRNOP00000069221

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,831,503 - 151,918,134 (+)	Ensembl
Rnor_6.0 Ensembl	5	158,069,725 - 158,128,523 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000088766 ⟹ ENSRNOP00000075011

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,857,371 - 151,901,630 (+)	Ensembl
Rnor_6.0 Ensembl	5	158,090,173 - 158,115,751 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000090593 ⟹ ENSRNOP00000069936

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,830,701 - 151,873,075 (+)	Ensembl
Rnor_6.0 Ensembl	5	158,042,587 - 158,083,311 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000092026 ⟹ ENSRNOP00000069040

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,857,371 - 151,904,072 (+)	Ensembl
Rnor_6.0 Ensembl	5	158,090,268 - 158,114,306 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095029 ⟹ ENSRNOP00000077405

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,858,983 - 151,918,134 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101164 ⟹ ENSRNOP00000083484

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,858,038 - 151,876,946 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117654 ⟹ ENSRNOP00000085310

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,909,648 - 151,925,345 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000120748 ⟹ ENSRNOP00000098374

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	157,162,945 - 157,187,254 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000120749 ⟹ ENSRNOP00000098375

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	157,162,945 - 157,188,673 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000134841 ⟹ ENSRNOP00000110221

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	157,162,945 - 157,184,817 (+)	Ensembl

RefSeq Acc Id:

NM_001134698 ⟹ NP_001128170

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	157,163,189 - 157,188,673 (+)	NCBI
mRatBN7.2	5	151,880,002 - 151,905,491 (+)	NCBI
Rnor_6.0	5	158,090,238 - 158,115,725 (+)	NCBI
Rnor_5.0	5	161,829,323 - 161,854,796 (+)	NCBI
RGSC_v3.4	5	158,437,691 - 158,453,827 (+)	RGD
Celera	5	150,256,652 - 150,282,086 (+)	RGD

Sequence:

show sequence

CAACCGCTCAAGACTCTTAGAACCTCTGTGATGCTGCCGCCGGCTTTGCTTCGCCGATCCCTGC
TGTCCTACGCCTGGAGGGGCTCTGGGCTGCGGTGGAAACATGCCTCCTCTCTGAAGGTGGCCAA
TGAGCCCATCTTAGCGTTTACTCAGGGCAGCCCCGAACGGGACGCACTGCAGAAGGCTCTGAAC
GACCTGAAGGACCAGACAGAAGCCATCCCCTGCGTTGTTGGGGACGAGGAGGTGTGGACCTCTG
ATGTGCGGTACCAGCTGTCGCCTTTTAACCATGGACACAAGGTGGCCAAGTTCTGTTATGCCGA
CAAGGCCTTGCTCAACAAAGCCATCGAAGCTGCCGTGCTTGCCAGGAAAGAGTGGGACCTGAAG
CCCGTGGCAGACCGGGCCCAGATCTTCCTGAAGGCGGCAGATATGCTGAGCGGGCCCCGAAGGG
CTGAAATCCTTGCCAAGACCATGGTGGGACAGGGCAAGACCGTAATCCAAGCAGAGATTGACGC
CGCAGCCGAACTCATCGACTTCTTCAGGTTCAATGCCAAGTTCGCCGTGGAACTGGAGGGGGAA
CAACCCATCAGCGTGCCACCCAGTACCAACCACGTGGTGTACCGGGGACTGGAGGGCTTCGTGG
CGGCCATCTCTCCCTTCAACTTCACCGCGATCGGAGGCAACCTGGCAGGCGCACCGGCCTTAAT
GGGCAACGTGGTTCTCTGGAAGCCCAGTGACACTGCCATGTTGGCTAGCTATGCTGTCTACCGC
ATCCTCCGGGAGGCCGGCTTGCCCCCCAACGTAATCCAGTTTGTGCCAGCTGATGGGCCGACAT
TCGGGGACACAGTCACCAGCTCAGAGCACCTCTGTGGTATCAACTTCACAGGCAGTGTGCCCAC
CTTTAAACACCTGTGGAAGCAGGTGGCCCAGAATCTGGACCGGTTCCGTACCTTCCCACGCCTG
GCTGGAGAGTGTGGCGGGAAGAATTTCCATTTCGTGCACAGCTCGGCCGACGTGGACAGCGTGG
TGAGCGGGACGCTGCGCTCGGCCTTCGAGTATGGCGGTCAGAAGTGCTCAGCCTGCTCGCGCCT
CTACGTGCCACAGTCTCTGTGGCCACAGATCAAAGGGCGACTGCTGGAGGAGCACAGCAGGATC
AAAGTGGGCAACCCTGCAGAGGACTTTGGGACCTTCTTCTCTGCAGTGATTGATGCCAAGGCCT
TCGCCCGCATAAAGAAGTGGCTGGAGCATGCGCGTTCCTCGCCCAGCCTCAGCATCCTGGCAGG
CGGCCAGTGTAACGAGTCGGTGGGTTACTTCGTGGAGCCGTGTATCATTGAGAGCAAGGACCCA
CAGGAGCCCATCATGAAGGAGGAGATCTTCGGCCCTGTGCTGACAGTGTATGTGTACCCGGATG
AGAAATACAGAGAGACGCTGCAACTGGTCGACAGCACCACCAGCTATGGCCTCACGGGGGCAGT
GTTTGCCCAGGATAAAACAATTGTCCAAGAAGCCACGAGGATGCTGAGGAACGCTGCTGGCAAC
TTCTACATCAACGACAAGTCTACTGGATCTGTGGTGGGCCAGCAGCCCTTTGGGGGCGCCCGGG
CCTCAGGAACCAATGACAAACCAGGAGGCCCCCACTACATCTTACGCTGGACCTCACCCCAGGT
CATCAAGGAGACTCATAAGCCCCTGGGGGACTGGCGATACTCCTACATGCAGTAACCCGGCCCA
GCACCTCTGTTGTCAAACCATCTGTCCATCCAAATGACAGACATCTCTGCACTGACCCCCCTGC
TCCCCAACCAGCTCCTCCTGGACTCTCTACAGCTGAGCTGGACCCTGCCCTGGCCACTGGGTAC
CTTTCCTTGGAATCAGGTGCCCAGTCATTGGCTTTGGTCATATTGGAGAGGATGAGCCAATCTA
CCCAGAAATCTCATCTGCTGGGGAACACCCTGGTACCTGGCAGGTTCTTCCCCTGACTGCTTTT
CTTGCCTCATCCTGGACCGGGTGACTCAGAGGCCCCGAGAACAGAGAGGGATATTTTCAGGATC
TTGTCAGGGAAGGAGACAACGCTGGTGTCCTGTAGCCTCACCACTCAAAGACTCCTGACCTTAG
CCTTGTCCCCTACACATGTCCACTGAGATAAGACCTTAGCCAGATGTCTGTCCGGGCACCAGCT
GGCTTTGCCCTTGGTCTGTGCTAGCTCCTCCTGCAGGTACTTGTGTCCAGCCATATGCCTTAGA
CCCATGTGCCTTCCTCCAGGGTGCCTGTGCATCCCTGAGACTTCATCCCTCCTGGCCACCTTCT
GGGAGTGACCAGTCATGGTCACCCCATACAGTCTGAATCTGGGAAGCCTCGAGATGGGCCTCCA
TTCCATACTCTTGTGCGATGCAGCCAGCCCAGAGGTAGCCAGGGTGAGCTCCTGCTTGGGTCCC
TGATAATCAAATGTTTCCAGTGGCTTGAGAGCATGTGGGGTTTCCTTTCAAGGACATTTGCCAG
GGGTCCGCATGGAGCTGGTATAGCTGTCACCAAGGGCTACCCTCATCACTCTCAGGGGCAGGCA
CCAGTACCAGGCCGGCTCTGTCCTGCTTCCTTTCAGGGTCCATGTTGCTTCCCAGGGAGCAGGG
CTAGACTGCAAATGTCCCGATTCTGCTGGTTCTATACTGTGAGGCGCATTTACTGCCACCTGAG
AAAATGCCAGATACCTACTCAAAGTGGCCACGGAGGGAGGTGAGGGGCGCACTGGATTCTCATT
CCTAATCTAACGAACTGCCAGCGACTTGTCGCATGGTTCTGTGTGATGCCACTGGAGGGAGTAG
TGACTCCGGTGCCCAGTGGTTGGGTTTAAATGGCTTTTTGTCTCCCCCACCCCCCAAGGTGGTC
ACCCAAAAAAACCATGTAAATTCTCTAACCTTTCATGTCTAAAATGGTGACGATTCCCTCATGT
ACCCGGAGGATCATTGAGCTAATCCCTGTGGATTTCAGATAAACGATTGGAAATGTCACCTGTT
TGTTTCTCAACCCTGTGTGCTGATCTTATGTGTCAGCTTTGCTGGGCCACAGTACCCAGAGACC
TGGTCAACCATTGTGGAAGGTGCCTTGAATGAGAGTAAAGTTTAAATAAATGAGCTCTTAAATT
TTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001128170	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68153	(Get FASTA)	NCBI Sequence Viewer
	EDL80928	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000098375
GenBank Protein	P0C2X9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001128170 ⟸ NM_001134698

- UniProtKB:

B4F768 (UniProtKB/TrEMBL), A6ITM7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLPPALLRRSLLSYAWRGSGLRWKHASSLKVANEPILAFTQGSPERDALQKALNDLKDQTEAIP
CVVGDEEVWTSDVRYQLSPFNHGHKVAKFCYADKALLNKAIEAAVLARKEWDLKPVADRAQIFL
KAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTN
HVVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPN
VIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFRTFPRLAGECGGKNFH
FVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPQSLWPQIKGRLLEEHSRIKVGNPAEDFG
TFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYFVEPCIIESKDPQEPIMKEEIF
GPVLTVYVYPDEKYRETLQLVDSTTSYGLTGAVFAQDKTIVQEATRMLRNAAGNFYINDKSTGS
VVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYMQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000069040 ⟸ ENSRNOT00000092026

Ensembl Acc Id:

ENSRNOP00000069221 ⟸ ENSRNOT00000080108

Ensembl Acc Id:

ENSRNOP00000069536 ⟸ ENSRNOT00000079516

Ensembl Acc Id:

ENSRNOP00000069936 ⟸ ENSRNOT00000090593

Ensembl Acc Id:

ENSRNOP00000072481 ⟸ ENSRNOT00000077863

Ensembl Acc Id:

ENSRNOP00000075011 ⟸ ENSRNOT00000088766

Ensembl Acc Id:

ENSRNOP00000077405 ⟸ ENSRNOT00000095029

Ensembl Acc Id:

ENSRNOP00000083484 ⟸ ENSRNOT00000101164

Ensembl Acc Id:

ENSRNOP00000085310 ⟸ ENSRNOT00000117654

Ensembl Acc Id:

ENSRNOP00000098375 ⟸ ENSRNOT00000120749

Ensembl Acc Id:

ENSRNOP00000110221 ⟸ ENSRNOT00000134841

Ensembl Acc Id:

ENSRNOP00000098374 ⟸ ENSRNOT00000120748

Protein Domains

Aldehyde dehydrogenase IF rod

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P0C2X9-F1-model_v2	AlphaFold	P0C2X9	1-563	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1624206	AgrOrtholog
BioCyc Gene	G2FUF-39408	BioCyc
BioCyc Pathway	ARGASEDEG-PWY [L-arginine degradation I (arginase pathway)]	BioCyc
	PROUT-PWY [L-proline degradation I]	BioCyc
BioCyc Pathway Image	ARGASEDEG-PWY	BioCyc
	PROUT-PWY	BioCyc
Ensembl Genes	ENSRNOG00000061876	Ensembl
	ENSRNOG00000071265	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000120749	ENTREZGENE
Gene3D-CATH	Aldehyde Dehydrogenase, Chain A, domain 1	UniProtKB/Swiss-Prot
	Aldehyde Dehydrogenase, Chain A, domain 2	UniProtKB/Swiss-Prot
InterPro	Ald_DH/histidinol_DH	UniProtKB/Swiss-Prot
	Ald_DH_C	UniProtKB/Swiss-Prot
	Ald_DH_CS_CYS	UniProtKB/Swiss-Prot
	Ald_DH_CS_GLU	UniProtKB/Swiss-Prot
	Ald_DH_N	UniProtKB/Swiss-Prot
	Aldehyde_DH_dom	UniProtKB/Swiss-Prot
	P5CDH/ALDH4A1	UniProtKB/Swiss-Prot
NCBI Gene	641316	ENTREZGENE
PANTHER	1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER	UniProtKB/Swiss-Prot
	DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL	UniProtKB/Swiss-Prot
Pfam	Aldedh	UniProtKB/Swiss-Prot
PhenoGen	Aldh4a1	PhenoGen
PROSITE	ALDEHYDE_DEHYDR_CYS	UniProtKB/Swiss-Prot
	ALDEHYDE_DEHYDR_GLU	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000061876	RatGTEx
	ENSRNOG00000071265	RatGTEx
Superfamily-SCOP	SSF53720	UniProtKB/Swiss-Prot
UniProt	A0A0G2JUB9_RAT	UniProtKB/TrEMBL
	A0A0G2JUT5_RAT	UniProtKB/TrEMBL
	A0A0G2JVM0_RAT	UniProtKB/TrEMBL
	A0A0G2K9I7_RAT	UniProtKB/TrEMBL
	A0A8I5YBT1_RAT	UniProtKB/TrEMBL
	A6ITM7	ENTREZGENE, UniProtKB/TrEMBL
	AL4A1_RAT	UniProtKB/Swiss-Prot
	B4F768	ENTREZGENE, UniProtKB/TrEMBL
	P0C2X9	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-12-02	Aldh4a1	aldehyde dehydrogenase 4 family, member A1	LOC641316	similar to aldehyde dehydrogenase 4 family, member A1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2007-05-03	LOC641316	similar to aldehyde dehydrogenase 4 family, member A1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

BioCyc Pathways