Prdm2 (PR/SET domain 2) - Rat Genome Database

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Gene: Prdm2 (PR/SET domain 2) Rattus norvegicus
Analyze
Symbol: Prdm2
Name: PR/SET domain 2
RGD ID: 1594531
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in response to estradiol. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in nucleus. Orthologous to human PRDM2 (PR/SET domain 2); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: PR domain 2; PR domain containing 2, with ZNF domain; PR domain containing 2, with ZNF domain (mapped); PR domain zinc finger protein 2; PR domain-containing protein 2; Prdm2_mapped; retinoblastoma interacting zinc finger protein; retinoblastoma protein-binding zinc finger protein; retinoblastoma protein-interacting zinc finger protein; Riz; zinc finger protein RIZ
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85160,704,396 - 160,815,184 (-)NCBIGRCr8
mRatBN7.25155,421,066 - 155,531,884 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5155,422,134 - 155,531,825 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5158,106,645 - 158,216,138 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05159,879,929 - 159,989,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05159,861,245 - 159,970,147 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05161,769,587 - 161,879,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5161,770,653 - 161,879,133 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05165,468,778 - 165,578,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45161,962,929 - 162,072,519 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5153,753,320 - 153,860,334 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prdm2Ratchromosome 1p36 deletion syndrome  ISOPRDM2 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 1p36 deletion syndromeClinVar 
Prdm2RatContracture  ISOPRDM2 (Homo sapiens)8554872ClinVar Annotator: match by term: ContracturesClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prdm2Ratamphetamine abuse  ISOPRDM2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18316681
Prdm2RatThyroid Neoplasms  ISOPRDM2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17103461
Prdm2Raturinary bladder cancer  ISOPRDM2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26039340

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prdm2Rat1,2-dimethylhydrazine increases expressionISOPrdm2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of PRDM2 mRNACTDPMID:22206623
Prdm2Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactionsISOPRDM2 (Homo sapiens)6480464[Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PRDM2 protein modified form]CTDPMID:28751236
Prdm2Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOPRDM2 (Homo sapiens)64804642 more ...CTDPMID:19095052
Prdm2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPRDM2 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of PRDM2 mRNACTDPMID:19684285
Prdm2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PRDM2 mRNACTDPMID:33387578
Prdm2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PRDM2 mRNACTDPMID:34747641
Prdm2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of PRDM2 mRNACTDPMID:22298810
Prdm2Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of PRDM2 mRNACTDPMID:21346803
Prdm2Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOPRDM2 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PRDM2 mRNACTDPMID:28628672
Prdm2Rat4,4'-diaminodiphenylmethane affects expressionISOPrdm2 (Mus musculus)64804644 and 4'-diaminodiphenylmethane affects the expression of PRDM2 mRNACTDPMID:18648102
Prdm2Rat4,4'-sulfonyldiphenol multiple interactionsISOPRDM2 (Homo sapiens)6480464[bisphenol S co-treated with Fulvestrant] results in increased methylation of PRDM2 gene and bisphenol S inhibits the reaction [ESR1 protein binds to PRDM2 protein]CTDPMID:29389661 and PMID:31601247
Prdm2Rat4,4'-sulfonyldiphenol increases expressionISOPrdm2 (Mus musculus)6480464bisphenol S results in increased expression of PRDM2 mRNACTDPMID:39298647
Prdm2Rat5-aza-2'-deoxycytidine affects expressionISOPRDM2 (Homo sapiens)6480464Decitabine affects the expression of PRDM2 mRNACTDPMID:17103461
Prdm2Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of PRDM2 mRNACTDPMID:30047161
Prdm2Ratacrolein multiple interactionsISOPRDM2 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PRDM2 mRNA more ...CTDPMID:32699268 and PMID:32845096
Prdm2Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of PRDM2 mRNACTDPMID:28959563
Prdm2Rataflatoxin B1 increases expressionISOPrdm2 (Mus musculus)6480464Aflatoxin B1 results in increased expression of PRDM2 mRNACTDPMID:19770486
Prdm2Rataflatoxin B1 increases methylationISOPRDM2 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of PRDM2 geneCTDPMID:27153756
Prdm2Ratall-trans-retinoic acid affects expressionISOPRDM2 (Homo sapiens)6480464Tretinoin affects the expression of PRDM2 mRNACTDPMID:15498508
Prdm2Ratalpha-pinene multiple interactionsISOPRDM2 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PRDM2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of PRDM2 mRNACTDPMID:32699268

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prdm2Ratchromatin remodeling involved_inIEAGO:00420541600115GO_REF:0000108GOCGO_REF:0000108
Prdm2Ratchromatin remodeling involved_inIEAGO:01409491600115GO_REF:0000108GOCGO_REF:0000108
Prdm2Ratdetermination of adult lifespan acts_upstream_of_or_withinISOPrdm2 (Mus musculus)1624291MGI:2388354 PMID:11544182RGDPMID:11544182
Prdm2Ratdetermination of adult lifespan acts_upstream_of_or_withinIEAUniProtKB:A2A7B5 and ensembl:ENSMUSP000001014041600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2Ratmethylation involved_inIEAUniProtKB-KW:KW-04891600115GO_REF:0000043UniProtGO_REF:0000043
Prdm2Ratnegative regulation of transcription by RNA polymerase II involved_inISOPRDM2 (Homo sapiens)1624291 PMID:9334209RGDPMID:9334209
Prdm2Ratnegative regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q13029 and ensembl:ENSP000003123521600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2Ratpositive regulation of transcription by RNA polymerase II involved_inISOPRDM2 (Homo sapiens)1624291 PMID:8654390RGDPMID:8654390
Prdm2Ratpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q13029 and ensembl:ENSP000003123521600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2Ratregulation of transcription by RNA polymerase II involved_inIBAPANTHER:PTN008358932 and UniProtKB:Q130291600115GO_REF:0000033GO_CentralGO_REF:0000033
Prdm2Ratresponse to estradiol  IDA 2316803 RGD 
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Cellular Component
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prdm2RatGolgi apparatus located_inISOPRDM2 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Prdm2RatGolgi apparatus located_inIEAUniProtKB:Q13029 and ensembl:ENSP000003123521600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2Ratnucleoplasm located_inIEAUniProtKB:Q13029 and ensembl:ENSP000003123521600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2Ratnucleoplasm located_inISOPRDM2 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Prdm2Ratnucleus located_inISOPRDM2 (Homo sapiens)1624291 PMID:11544182RGDPMID:11544182
Prdm2Ratnucleus located_inIEAUniProtKB:Q13029 and ensembl:ENSP000003123521600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Prdm2Ratnucleus is_active_inIBAFB:FBgn0035625 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Prdm2Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
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Molecular Function
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prdm2RatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
Prdm2RatDNA-binding transcription activator activity, RNA polymerase II-specific enablesISOPRDM2 (Homo sapiens)1624291 PMID:8654390RGDPMID:8654390
Prdm2RatDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAUniProtKB:Q13029 and ensembl:ENSP000003123521600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2RatDNA-binding transcription factor activity, RNA polymerase II-specific enablesIBAPANTHER:PTN008358932 and UniProtKB:Q130291600115GO_REF:0000033GO_CentralGO_REF:0000033
Prdm2RatDNA-binding transcription repressor activity, RNA polymerase II-specific enablesISOPRDM2 (Homo sapiens)1624291 PMID:9334209RGDPMID:9334209
Prdm2RatDNA-binding transcription repressor activity, RNA polymerase II-specific enablesIEAUniProtKB:Q13029 and ensembl:ENSP000003123521600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2Rathistone H3K9 trimethyltransferase activity enablesIEARHEA:602761600115GO_REF:0000116RHEAGO_REF:0000116
Prdm2Rathistone H3K9 trimethyltransferase activity enablesIEAEC:2.1.1.3551600115GO_REF:0000003UniProtGO_REF:0000003
Prdm2Rathistone methyltransferase activity enablesIEAInterPro:IPR009170 and InterPro:IPR0444141600115GO_REF:0000002InterProGO_REF:0000002
Prdm2Rathistone methyltransferase activity enablesIEARHEA:100241600115GO_REF:0000116RHEAGO_REF:0000116
Prdm2Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Prdm2Ratmethyltransferase activity enablesIEAUniProtKB-KW:KW-04891600115GO_REF:0000043UniProtGO_REF:0000043
Prdm2Ratprotein binding enablesISOPRDM2 (Homo sapiens)1624291UniProtKB:P06400 and PMID:25640033RGDPMID:25640033
Prdm2Ratprotein binding  IPIRB1 (Homo sapiens)2316804 RGD 
Prdm2RatRNA polymerase II transcription regulatory region sequence-specific DNA binding enablesISOPRDM2 (Homo sapiens)1624291 PMID:8654390RGDPMID:8654390
Prdm2RatRNA polymerase II transcription regulatory region sequence-specific DNA binding enablesIEAUniProtKB:Q13029 and ensembl:ENSP000003123521600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2Ratsequence-specific DNA binding enablesISOPRDM2 (Homo sapiens)1624291 PMID:9334209RGDPMID:9334209
Prdm2Ratsequence-specific DNA binding enablesIEAUniProtKB:Q13029 and ensembl:ENSP000003123521600115GO_REF:0000107EnsemblGO_REF:0000107
Prdm2Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
Prdm2Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
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RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prdm2Rathistone modification pathway   ISOPRDM2 (Homo sapiens)7242632 RGD 

#
Reference Title
Reference Citation
1. The retinoblastoma-interacting zinc-finger protein RIZ is a downstream effector of estrogen action. Abbondanza C, etal., Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3130-5.
2. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
3. The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein. Buyse IM, etal., Proc Natl Acad Sci U S A. 1995 May 9;92(10):4467-71.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8654390   PMID:9334209   PMID:11544182   PMID:27573876  



Prdm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85160,704,396 - 160,815,184 (-)NCBIGRCr8
mRatBN7.25155,421,066 - 155,531,884 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5155,422,134 - 155,531,825 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5158,106,645 - 158,216,138 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05159,879,929 - 159,989,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05159,861,245 - 159,970,147 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05161,769,587 - 161,879,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5161,770,653 - 161,879,133 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05165,468,778 - 165,578,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45161,962,929 - 162,072,519 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5153,753,320 - 153,860,334 (-)NCBICelera
Cytogenetic Map5q36NCBI
PRDM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38113,700,188 - 13,825,079 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl113,700,188 - 13,825,079 (+)EnsemblGRCh38hg38GRCh38
GRCh37114,026,683 - 14,151,574 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36113,903,937 - 14,024,162 (+)NCBINCBI36Build 36hg18NCBI36
Build 34113,776,655 - 13,859,875NCBI
Celera112,508,705 - 12,633,526 (+)NCBICelera
Cytogenetic Map1p36.21NCBI
HuRef112,544,696 - 12,669,465 (+)NCBIHuRef
CHM1_1113,825,064 - 13,950,026 (+)NCBICHM1_1
T2T-CHM13v2.0113,142,270 - 13,267,189 (+)NCBIT2T-CHM13v2.0
Prdm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394142,833,961 - 142,939,560 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4142,833,961 - 142,939,565 (-)EnsemblGRCm39 Ensembl
GRCm384143,107,391 - 143,212,769 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4143,107,391 - 143,212,995 (-)EnsemblGRCm38mm10GRCm38
MGSCv374142,697,294 - 142,802,612 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364142,394,156 - 142,479,396 (-)NCBIMGSCv36mm8
Celera4144,915,482 - 145,028,265 (-)NCBICelera
Cytogenetic Map4E1NCBI
cM Map476.84NCBI
Prdm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555274,012,332 - 4,105,311 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555274,005,410 - 4,105,376 (-)NCBIChiLan1.0ChiLan1.0
PRDM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21213,094,678 - 213,224,420 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,342,327 - 212,472,168 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0112,838,201 - 12,963,735 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1113,853,829 - 13,910,800 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl113,853,895 - 13,961,610 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl113,853,895 - 13,961,610 (+)NCBIpanpan1.1panPan2
PRDM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1283,381,021 - 83,429,640 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl283,382,552 - 83,465,687 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha279,917,102 - 80,036,570 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0284,031,028 - 84,150,815 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl284,031,037 - 84,150,473 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1280,784,169 - 80,888,460 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0281,802,556 - 81,922,434 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0282,869,382 - 82,989,085 (-)NCBIUU_Cfam_GSD_1.0
Prdm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505836,081,381 - 36,129,727 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364741,862,898 - 1,949,500 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364741,910,026 - 1,924,900 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRDM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl673,118,177 - 73,239,423 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1673,135,872 - 73,240,271 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2667,387,475 - 67,455,877 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRDM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120118,437,171 - 118,565,554 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20118,436,717 - 118,550,461 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605422,166,785 - 22,295,971 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prdm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624764276,893 - 384,270 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624764261,451 - 384,270 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Prdm2
613 total Variants

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:82
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000041175
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 30 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat

1 to 10 of 30 rows
D5Got96  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25155,532,103 - 155,532,450 (+)MAPPERmRatBN7.2
Rnor_6.05161,879,412 - 161,879,758NCBIRnor6.0
Rnor_5.05165,578,603 - 165,578,949UniSTSRnor5.0
RGSC_v3.45162,072,797 - 162,073,144RGDRGSC3.4
RGSC_v3.45162,072,798 - 162,073,144UniSTSRGSC3.4
RGSC_v3.15162,082,986 - 162,083,332RGD
Celera5153,860,613 - 153,860,959UniSTS
RH 3.4 Map51058.6UniSTS
RH 3.4 Map51058.6RGD
RH 2.0 Map51091.8RGD
Cytogenetic Map5q36UniSTS
42.MMHAP20FRF12.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25155,499,161 - 155,499,335 (+)MAPPERmRatBN7.2
Rnor_6.05161,847,761 - 161,847,934NCBIRnor6.0
Rnor_5.05165,546,952 - 165,547,125UniSTSRnor5.0
RGSC_v3.45162,040,518 - 162,040,691UniSTSRGSC3.4
Celera5153,830,112 - 153,830,285UniSTS
Cytogenetic Map5q36UniSTS
BE120443  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25155,446,444 - 155,446,597 (+)MAPPERmRatBN7.2
Rnor_6.05161,794,757 - 161,794,909NCBIRnor6.0
Rnor_5.05165,493,948 - 165,494,100UniSTSRnor5.0
RGSC_v3.45161,987,221 - 161,987,373UniSTSRGSC3.4
Celera5153,777,437 - 153,777,589UniSTS
RH 3.4 Map51057.9UniSTS
Cytogenetic Map5q36UniSTS
RH135296  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25155,422,169 - 155,422,381 (+)MAPPERmRatBN7.2
Rnor_6.05161,770,689 - 161,770,900NCBIRnor6.0
Rnor_5.05165,469,880 - 165,470,091UniSTSRnor5.0
RGSC_v3.45161,962,965 - 161,963,176UniSTSRGSC3.4
Celera5153,753,356 - 153,753,567UniSTS
RH 3.4 Map51058.2UniSTS
Cytogenetic Map5q36UniSTS
ksks160  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25155,447,866 - 155,448,175 (+)MAPPERmRatBN7.2
Rnor_6.05161,796,179 - 161,796,487NCBIRnor6.0
Rnor_5.05165,495,370 - 165,495,678UniSTSRnor5.0
RGSC_v3.45161,988,643 - 161,988,951UniSTSRGSC3.4
Celera5153,778,859 - 153,779,167UniSTS
Cytogenetic Map5q36UniSTS
PMC312773P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25155,479,438 - 155,479,558 (+)MAPPERmRatBN7.2
Rnor_6.05161,827,987 - 161,828,106NCBIRnor6.0
Rnor_5.05165,527,178 - 165,527,297UniSTSRnor5.0
RGSC_v3.45162,020,799 - 162,020,918UniSTSRGSC3.4
Celera5153,810,393 - 153,810,512UniSTS
Cytogenetic Map5q36UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000041175   ⟹   ENSRNOP00000046011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5155,422,134 - 155,531,825 (-)Ensembl
Rnor_6.0 Ensembl5161,770,653 - 161,879,133 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078237   ⟹   ENSRNOP00000072686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5161,773,758 - 161,875,362 (-)Ensembl
RefSeq Acc Id: NM_001077648   ⟹   NP_001071116
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85160,705,462 - 160,815,140 (-)NCBI
mRatBN7.25155,422,134 - 155,531,825 (-)NCBI
Rnor_6.05161,770,653 - 161,879,133 (-)NCBI
Rnor_5.05165,468,778 - 165,578,775 (-)NCBI
RGSC_v3.45161,962,929 - 162,072,519 (-)RGD
Celera5153,753,320 - 153,860,334 (-)RGD
Sequence:
RefSeq Acc Id: XM_017593426   ⟹   XP_017448915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85160,708,565 - 160,815,151 (-)NCBI
mRatBN7.25155,421,066 - 155,531,852 (-)NCBI
Rnor_6.05161,769,587 - 161,879,138 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110087   ⟹   XP_038966015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85160,708,565 - 160,815,154 (-)NCBI
mRatBN7.25155,421,066 - 155,531,852 (-)NCBI
RefSeq Acc Id: XM_039110090   ⟹   XP_038966018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85160,708,565 - 160,742,653 (-)NCBI
mRatBN7.25155,421,066 - 155,459,327 (-)NCBI
RefSeq Acc Id: XM_063287820   ⟹   XP_063143890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85160,726,101 - 160,815,184 (-)NCBI
RefSeq Acc Id: XM_063287821   ⟹   XP_063143891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85160,708,565 - 160,780,912 (-)NCBI
RefSeq Acc Id: XM_063287822   ⟹   XP_063143892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85160,704,396 - 160,815,184 (-)NCBI
RefSeq Acc Id: NP_001071116   ⟸   NM_001077648
- UniProtKB: Q63755 (UniProtKB/Swiss-Prot),   F1LQ66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448915   ⟸   XM_017593426
- Peptide Label: isoform X1
- UniProtKB: Q63755 (UniProtKB/Swiss-Prot),   F1LQ66 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000046011   ⟸   ENSRNOT00000041175
Ensembl Acc Id: ENSRNOP00000072686   ⟸   ENSRNOT00000078237
RefSeq Acc Id: XP_038966015   ⟸   XM_039110087
- Peptide Label: isoform X1
- UniProtKB: Q63755 (UniProtKB/Swiss-Prot),   F1LQ66 (UniProtKB/TrEMBL)
C2H2-type   SET

Name Modeler Protein Id AA Range Protein Structure
AF-Q63755-F1-model_v2 AlphaFold Q63755 1-1706 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694240
Promoter ID:EPDNEW_R4765
Type:multiple initiation site
Name:Prdm2_1
Description:PR/SET domain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05161,879,146 - 161,879,206EPDNEW


1 to 36 of 36 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-39304 BioCyc
Ensembl Genes ENSRNOG00000033522 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000041175 ENTREZGENE
  ENSRNOT00000124287 ENTREZGENE
Gene3D-CATH 2.170.270.10 UniProtKB/Swiss-Prot
  Classic Zinc Finger UniProtKB/Swiss-Prot
InterPro PRDM2_PR-SET UniProtKB/Swiss-Prot
  RIZ_retinblastoma-bd_prot UniProtKB/Swiss-Prot
  SET_dom UniProtKB/Swiss-Prot
  SET_dom_sf UniProtKB/Swiss-Prot
  Zinc_finger UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report rno:313678 UniProtKB/Swiss-Prot
NCBI Gene 313678 ENTREZGENE
PANTHER PR DOMAIN ZINC FINGER PROTEIN UniProtKB/Swiss-Prot
  PR DOMAIN ZINC FINGER PROTEIN 2 UniProtKB/Swiss-Prot
Pfam PRDM2_PR UniProtKB/Swiss-Prot
  zf-C2H2 UniProtKB/Swiss-Prot
  zf-C2H2_6 UniProtKB/Swiss-Prot
PharmGKB PRDM2 RGD
PhenoGen Prdm2 PhenoGen
PIRSF RIZ_SET UniProtKB/Swiss-Prot
PROSITE SET UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000033522 RatGTEx
SMART SET UniProtKB/Swiss-Prot
  ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
  SSF82199 UniProtKB/Swiss-Prot
UniProt A6ITZ0_RAT UniProtKB/TrEMBL
  A6ITZ1_RAT UniProtKB/TrEMBL
  A6ITZ2_RAT UniProtKB/TrEMBL
  F1LQ66 ENTREZGENE, UniProtKB/TrEMBL
  PRDM2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 36 of 36 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-27 Prdm2  PR/SET domain 2  Prdm2  PR domain 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Prdm2  PR domain 2  Prdm2  PR domain containing 2, with ZNF domain  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   PR domain containing 2, with ZNF domain  Prdm2  PR domain containing 2, with ZNF domain (mapped)  Name updated 737654 APPROVED
2007-04-12 Prdm2  PR domain containing 2, with ZNF domain (mapped)  Prdm2_mapped  PR domain containing 2, with ZNF domain (mapped)  Data merged from RGD:3386 737654 APPROVED
2006-11-20 Prdm2  PR domain containing 2, with ZNF domain (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Prdm2_mapped  PR domain containing 2, with ZNF domain (mapped)  Prdm2  PR domain containing 2, with ZNF domain  Symbol and Name updated 1556543 APPROVED
2001-11-30 Prdm2  PR domain containing 2, with ZNF domain      Symbol and Name updated to reflect Human and Mouse nomenclature 68913 APPROVED
2001-11-30 Riz  Retinoblastoma interacting zinc finger protein      Symbol and Name withdrawn 68913 WITHDRAWN

Note Type Note Reference
gene_product member of the PR domain family, a subset of Krüppel-like zinc finger genes 1300403